Immunological Aspects of Polymer Microsphere Vaccine Delivery Systems

References

• Almeida, A.J. and Alpar, H.O. (1996) “Nasal delivery of vaccines”, Journal of Drug Targeting 3, 455–467.
   PubMed Web of Science ®Google Scholar
• Alpar, H.O., Eyles, J.E. and Williamson, E.D. (1998) “Oral and nasal immunization with microencapsulated clinically relevant proteins”, STP Pharma Sciences 8, 31–39.
   Google Scholar
• Alpar, H.O., Eyles, J.E., Williamson, E.D. and Somavarapu, S. (2001) “Intranasal vaccination against plague, tetanus and diphtheria”, Advanced Drug Delivery Reviews 51, 173–201.
   PubMed Web of Science ®Google Scholar
• Audran, R., Peter, K., Dannull, J., Men, Y., Scandella, E., Groettrup, M., Gander, B. and Corradin, G. (2003) “Encapsulation of peptides in biodegradable microspheres prolongs their MHC class– I presentation by dendritic cells and macrophages in vitro”, Vaccine 21, 1250–1255.
   PubMed Web of Science ®Google Scholar
• Bienstock, J. (1984) “The lung as an immunologic organ”, Annual Review of Medicine 35, 49–62.
   PubMed Web of Science ®Google Scholar
• Brandtzaeg, P. (1992) “Humoral immune– response patterns of human mucosae—induction and relation to bacterial respiratory– tract infections”, Journal of Infectious Diseases 165, S167–S176.
   PubMed Web of Science ®Google Scholar
• Breiman, R.F., Butler, J.C. and McInnes, P.M. (1999) “Vaccines to prevent respiratory infection: opportunities on the near and far horizon”, Current Opinion in Infectious Diseases 12, 145–152.
   PubMed Web of Science ®Google Scholar
• Byersdorfer, C.A. and Chaplin, D.D. (2001) “Visualization of early APC/T cell interactions in the mouse lung following intranasal challenge”, Journal of Immunology 167, 6756–6764.
   PubMed Web of Science ®Google Scholar
• Chelen, C.J., Fang, Y., Freeman, G.J., Secrist, H., Marshall, J.D., Hwang, P.T., Frankel, L.R., Dekruyff, R.H. and Umetsu, D.T. (1995) “Human alveolar macrophages present antigen ineffectively due to defective expression of B7 costimulatory cell– surface molecules”, Journal of Clinical Investigation 95, 1415–1421.
   PubMed Web of Science ®Google Scholar
• Davis, S.S. (2001) “Nasal vaccines”, Advanced Drug Delivery Reviews 51, 21–42.
   PubMed Web of Science ®Google Scholar
• Eldridge, J.H., Staas, J.K., Chen, D.X., Marx, P.A., Tice, T.R. and Gilley, R.M. (1993) “New advances in vaccine delivery systems”, Seminars in Hematology 30, 16–25.
   Google Scholar
• Eyles, J.E., Bramwell, V.W., Williamson, E.D. and Alpar, H.O. (2001) “Microsphere translocation and immunopotentiation in systemic tissues following intranasal administration”, Vaccine 19, 4732–4742.
   PubMed Web of Science ®Google Scholar
• Flick– Smith, H.C., Eyles, J.E., Hebdon, R., Waters, E.L., Beedham, R.J., Stagg, T.J., Miller, J., Alpar, H.O., Baillie, L.W.J. and Williamson, E.D. (2002) “Mucosal or parenteral administration of microsphere– associated Bacillus anthracis protective antigen protects against anthrax infection in mice”, Infection and Immunity 70, 2022–2028.
   PubMed Web of Science ®Google Scholar
• Florence, A.T., Hillery, A.M., Hussain, N. and Jani, P.U. (1995) “Factors affecting the oral uptake and translocation of polystyrene nanoparticles—histological and analytical evidence”, Journal of Drug Targeting 3, 65–70.
   PubMed Web of Science ®Google Scholar
• Gebert, A. and Pabst, R. (1999) “M cells at locations outside the gut”, Seminars in Immunology 11, 165–170.
   Google Scholar
• Giannasca, P.J., Boden, J.A. and Monath, T.P. (1997) “Targeted delivery of antigen to hamster nasal lymphoid tissue with M– cell– directed lectins”, Infection and Immunity 65, 4288–4298.
   PubMed Web of Science ®Google Scholar
• Hacker, G., Redecke, V. and Hacker, H. (2002) “Activation of the immune system by bacterial CpG– DNA”, Immunology 105, 245–251. Harmsen, A.G., Muggenburg, B.A., Snipes, M.B. and Bice, D.E. (1985) “The role of macrophages in particle translocation from lungs to lymph nodes”, Science 230, 1277–1280.
   Google Scholar
• Hemmi, H., Takeuchi, O., Kawai, T., Kaisho, T., Sato, S., Sanjo, H., Matsumoto, M., Hoshino, K., Wagner, H., Takeda, K. and Akira, S. (2000) “A Toll– like receptor recognizes bacterial DNA”, Nature 408, 740–745.
   PubMed Web of Science ®Google Scholar
• Heritage, P.L., Underdown, B.J., Arsenault, A.L., Snider, D.P. and McDermott, M.R. (1997) “Comparison of murine nasal– associated lymphoid tissue and Peyer’s patches”, American Journal of Respiratory and Critical Care Medicine 156, 1256–1262.
   PubMed Web of Science ®Google Scholar
• Holt, P.G. (1986) “Down– regulation of immune– responses in the lower respiratory– tract—the role of alveolar macrophages”, Clinical and Experimental Immunology 63, 261–270.
   PubMed Web of Science ®Google Scholar
• Holt, P.G. and Schonhegrad, M.A. (1987) “Localization of T– cells, macrophages and dendritic cells in rat respiratory– tract tissue— implications for immune function studies”, Immunology 62, 349–356.
   PubMed Web of Science ®Google Scholar
• Holt, P.G., Degebrodt, A., Venaille, T., Oleary, C., Krska, K., Flexman, J., Farrell, H., Shellam, G., Young, P., Penhale, J., Robertson, T. and Papadimitrious, J.M. (1985) “Preparation of interstitial lung– cells by enzymatic digestion of tissue– slices—preliminary characterization by morphology and performance in functional assays”, Immunology 54, 139–147.
   PubMed Web of Science ®Google Scholar
• Janeway, C.A. and Medzhitov, R. (1998) “Introduction: the role of innate immunity in the adaptive immune response”, Seminars in Immunology 10, 349–350.
   Google Scholar
• McGhee, J.R., Mestecky, J., Dertzbaugh, M.T., Eldridge, J.H., Hirasawa, M. and Kiyono, H. (1992) “The mucosal immune– system—from fundamental– concepts to vaccine develop– ment”, Vaccine 10, 75–88.
   PubMed Web of Science ®Google Scholar
• Miller, J., McBride, B.W., Manchee, R.J., Moore, P. and Baillie, L.W.J. (1998) “Production and purification of recombinant protective antigen and protective efficacy against Bacillus anthracis”, Letters in Applied Microbiology 26, 56–60.
   PubMed Web of Science ®Google Scholar
• Mueller, D.L., Jenkins, M.K. and Schwartz, R.H. (1989) “Clonal expansion versus functional clonal inactivation—a costimulatory signaling pathway determines the outcome of T– cell antigen receptor occupancy”, Annual Review of Immunology 7, 445–480.
   PubMed Web of Science ®Google Scholar
• Newman, K.D., Elamanchili, P., Kwon, G.S. and Samuel, J. (2002) “Uptake of poly(D,L– lactic– co– glycolic acid) microspheres by antigen– presenting cells in vivo”, Journal of Biomedical Materials Research 60, 480–486.
   PubMed Web of Science ®Google Scholar
• Nugent, J., Po, A.L.W. and Scott, E.M. (1998) “Design and delivery of non– parenteral vaccines”, Journal of Clinical Pharmacy and Therapeutics 23, 257–285.
   PubMed Web of Science ®Google Scholar
• Ogra, P.L., Faden, H. and Welliver, R.C. (2001) “Vaccination strategies for mucosal immune responses”, Clinical Microbiology Reviews 14, 641-641, Vol. 14, p. 430, 2001.
   Google Scholar
• O’Hagan, D.T. (1998) “Recent advances in vaccine adjuvants for systemic and mucosal administration”, Journal of Pharmacy and Pharmacology 50, 1–10.
   PubMed Web of Science ®Google Scholar
• O’Hagan, D.T., McGee, J.P., Holmgren, J., Mowat, A., Donachie, A.M., Mills, K.H.G., Gaisford, W., Rahman, D. and Challacombe, S.J. (1993) “Biodegradable microparticles for oral immunization”, Vaccine 11, 149–154.
   PubMed Web of Science ®Google Scholar
• Poltorak, A., He, X.L., Smirnova, I., Liu, M.Y., Van Huffel, C., Du, X., Birdwell, D., Alejos, E., Silva, M., Galanos, C., Freudenberg, M., Ricciardi– Castagnoli, P., Layton, B. and Beutler, B. (1998) “Defective LPS signaling in C3H/HeJ and C57BL/10ScCr mice: mutations in Tlr4 gene”, Science 282, 2085–2088.
   PubMed Web of Science ®Google Scholar
• Raychaudhuri, S. and Rock, K.L. (1998) “Fully mobilizing host defense: building better vaccines”, Nature Biotechnology 16, 1025–1031.
   PubMed Web of Science ®Google Scholar
• Reyes, V.E., Ye, G., Ogra, P.L. and Garofalo, R. (1997) “Antigen presentation of mucosal pathogens: the players and the rules”, International Archives of Allergy and Immunology 112, 103–114.
   PubMed Web of Science ®Google Scholar
• Reynolds, H.Y. (1987) “Bronchoalveolar lavage”, American Review of Respiratory Disease 135, 250–263.
   PubMed Web of Science ®Google Scholar
• Schijns, V. (2000) “Immunological concepts of vaccine adjuvant activity—commentary”, Current Opinion in Immunology 12, 456–463.
   PubMed Web of Science ®Google Scholar
• Sun, H.F., Pollock, K.G.J. and Brewer, J.M. (2003) “Analysis of the role of vaccine adjuvants in modulating dendritic cell activation and antigen presentation in vitro”, Vaccine 21, 849–855.
   Google Scholar
• Tschernig, T. and Pabst, R. (2000) “Bronchus– associated lymphoid tissue (BALT) is not present in the normal adult lung but in different diseases”, Pathobiology 68, 1–8.
   PubMed Web of Science ®Google Scholar
• Vajdy, M. and O’Hagan, D.T. (2001) “Microparticles for intranasal immunization”, Advanced Drug Delivery Reviews 51, 127–141.
   PubMed Web of Science ®Google Scholar
• Vermaelen, K.Y., Carro– Muino, I., Lambrecht, B.N. and Pauwels, R.A. (2001) “Specific migratory dendritic cells rapidly transport antigen from the airways to the thoracic lymph nodes”, Journal of Experimental Medicine 193, 51–60.
   PubMed Web of Science ®Google Scholar
• Westwood, A., Healey, G.D., W.E., D. and Eyles, J.E. (2003) “Activation of dendritic cells after microparticulate uptake”, Proceedings of the 30th Annual Meeting of the Controlled Release Society 30, 4. Zinkernagel, R.M., Ehl, S., Aichele, P., Oehen, S., Kundig, T. and Hengartner, H. (1997) “Antigen localisation regulates immune responses in a dose– and time– dependent fashion: a geographical view of immune reactivity”, Immunological Reviews 156, 199–209.
   Google Scholar