Archaeosomes as Self-adjuvanting Delivery Systems for Cancer Vaccines_*

References

• Berzofsky, J.A., Ahlers, J.D. and Belyakov, I.M. (2001) “Strategies for designing and optimizing new generation vaccines”, Nat. Rev. Immunol. 1, 209–219.
   Google Scholar
• Beveridge, T.J., Choquet, C.G., Patel, G.B. and Sprott, G.D. (1993) “Freeze-fracture planes of methanogen membranes correlate with the content of tetraether lipids”, J. Bacteriol. 175, 1191–1197.
   PubMed Web of Science ®Google Scholar
• Bhardwaj, N. (2001) “Processing and presentation of antigens by dendritic cells: implications for vaccines”, Trends Mol. Med. 7, 388–394.
   Web of Science ®Google Scholar
• Bloom, M.B., Perry-Lalley, D., Robbins, P.F., Li, Y., El-Gamil, M., Rosenberg, S.A. and Yang, J.C. (1997) “Identification of tyrosinase- related protein 2 as a tumor rejection antigen for the B16 melanoma”, J. Exp. Med. 185, 453–459.
   PubMed Web of Science ®Google Scholar
• Brewer, J.M., Conacher, M., Hunter, C.A., Mohrs, M., Brombacher, F. and Alexander, J. (1999) “Aluminium hydroxide adjuvant initiates strong antigen-specific Th2 responses in the absence of IL-4- or IL-13-mediated signaling”, J. Immunol. 163, 6448–6454.
   Web of Science ®Google Scholar
• Chang, J.S., Choi, M.J., Cheong, H.S. and Kim, K. (2001) “Development of Th1-mediated CD8+ effector T cells by vaccination with epitope peptides encapsulated in pH-sensitive liposomes”, Vaccine 19, 3608–3614.
   PubMed Web of Science ®Google Scholar
• Cippitelli, M. and Santoni, A. (1998) “Vitamin D3: a transcriptional modulator of the interferon-gamma gene”, Eur. J. Immunol. 28, 3017–3030.
   Web of Science ®Google Scholar
• Cirillo, J.D., Stover, C.K., Bloom, B.R., Jacobs-WR, J. and Barletta, R.G. (1995) “Bacterial vaccine vectors and bacillus Calmette-Guerin”, Clin. Infect. Dis. 20, 1001–1009.
   Google Scholar
• Clavreul, A., D’hellencourt, C.L., Montero Menei, C., Potron, G. and Couez, D. (1998) “Vitamin D differentially regulates B7.1 and B7.2 expression on human peripheral blood monocytes”, Immunology 95, 272–277.
   PubMed Web of Science ®Google Scholar
• Dallal, R.M. and Lotze, M.T. (2000) “The dendritic cell and human cancer vaccines”, Curr. Opin. Immunol. 12, 583–588.
   PubMed Web of Science ®Google Scholar
• East, L. and Isacke, C.M. (2002) “The mannose receptor family”, Biochim. Biophys. Acta 1572, 364–386.
   PubMed Web of Science ®Google Scholar
• Fadok, V.A., Bratton, D.L., Rose, D.M., Pearson, A., Ezekewitz, R.A. and Henson, P.M. (2000) “A receptor for phosphatidylserine-specific clearance of apoptotic cells”, Nature 405, 85–90.
   PubMed Web of Science ®Google Scholar
• Fernandez, N.C., Lozier, A., Flament, C., Ricciardi, C.P., Bellet, D., Suter, M., Perricaudet, M., Tursz, T., Maraskovsky, E. and Zitvogel, L. (1999) “Dendritic cells directly trigger NK cell functions: cross-talk relevant in innate anti-tumor immune responses in vivo”, Nat. Med. 5, 405–411.
   Web of Science ®Google Scholar
• Ferrante, G., Richards, J.C. and Sprott, G.D. (1990) “Structures of polar lipids from the thermophilic, deep-sea archaeobacterium Methano- coccus jannaschii”, Biochem. Cell Biol. 68, 274–283.
   Web of Science ®Google Scholar
• Folkers, K., Morita, M. and McRee, J., Jr. (1993) “The activities of coenzyme Q10 and vitamin B6 for immune responses”, Biochem. Biophys. Res. Commun. 193, 88–92.
   PubMed Web of Science ®Google Scholar
• Gupta, R.K., Rost, B.E., Reyveld, R.E. and Siber, G.S. (1995) “Adjuvant properties of aluminum and calcium compounds”, In: Powell, M.F. and Newman, M.J., eds, Vaccine Design: The Subunit and Adjuvant Approach (Plenum Press, New York), pp 229–248.
   Google Scholar
• Heath, A.W. (2001) “Recent advances in vaccinology”, Curr. Opin. Pharmacol. 1, 425–430.
   PubMedGoogle Scholar
• Heckelsmiller, K., Rall, K., Beck, S., Schlamp, A., Seiderer, J., Jahrsdorfer, B., Krug, A., Rothenfusser, S., Endres, S. and
   Google Scholar
• Hartmann, G. (2002) “Peritumoral CpG DNA elicits a coordinated response of CD8 T cells and innate effectors to cure established tumors in a murine colon carcinoma model”, J. Immunol. 169, 3892–3899.
   Web of Science ®Google Scholar
• Henkart, P.A. (1997) “CTL effector functions”, Semin. Immunol. 9, 85–86.
   Google Scholar
• Jager, E., Jager, D. and Knuth, A. (2002) “Clinical cancer vaccine trials”, Curr. Opin. Immunol. 14, 178–182.
   PubMed Web of Science ®Google Scholar
• Jeannin, P., Renno, T., Goetsch, L., Miconnet, I., Aubry, J.P., Delneste, Y., Herbault, N., Baussant, T., Magistrelli, G., Soulas, C., Romero, P., Cerottini, J.C. and Bonnefoy, J.Y. (2000) “OmpA targets dendritic cells, induces their maturation and delivers antigen into the MHC class I presentation pathway”, Nat. Immunol. 1, 502–509.
   Web of Science ®Google Scholar
• Kaisho, T. and Akira, S. (2002) “Toll-like receptors as adjuvant receptors”, Biochim. Biophys. Acta 1589, 1–13.
   PubMed Web of Science ®Google Scholar
• Kamekura, M. and Kates, M. (1999) “Structural diversity of membrane lipids in members of Halobacteriaceae”, Biosci. Biotechnol. Biochem. 63, 969–972.
   Web of Science ®Google Scholar
• Kates, M. (1986) “Techniques in Lipidology”, Laboratory Techniques in Biochemistry and Molecular Biology (Elsevier, Amsterdam), pp 225–242.
   Google Scholar
• Kates, M. (1992) “Archaebacterial lipids: structure,biosynthesis and function”, Biochem. Soc. Symp. 58, 51–72.
   Google Scholar
• Kirby, C.J. and Gregoriadis, G. (1984) “Preparation of liposomes containing factor VIII for oral treatment of haemophilia”, J. Microencapsul. 1, 33–45.
   PubMedGoogle Scholar
• Krishnan, L., Dicaire, C.J., Patel, G.B. and Sprott, G.D. (2000a) “Archaeosome vaccine adjuvants induce strong humoral, cell- mediated and memory responses: comparison to conventional liposomes and alum”, Infect. Immun. 68, 54–63.
   Google Scholar
• Krishnan, L., Sad, S., Patel, G.B. and Sprott, G.D. (2000b) “Archaeosomes induce long-term CD8+ cytotoxic T cell response to entrapped soluble protein by the exogenous cytosolic pathway in the absence of CD4+ T cell help”, J. Immunol. 165, 5177–5185.
   Web of Science ®Google Scholar
• Krishnan, L., Sad, S., Patel, G.B. and Sprott, G.D. (2001) “The potent adjuvant acitivity of archaeosomes correlates to the recruitment and activation of macrophages and dendritic cells in vivo”, J. Immunol. 166, 1885–1893.
   Web of Science ®Google Scholar
• Krishnan, L., Sad, S., Patel, G.B. and Sprott, G.D. (2003) “Archaeosomes induce enhanced cytotoxic T lymphocyte responses to entrapped soluble protein in the absence of interleukin 12 and protect against tumor challenge”, Cancer Res. 63, 2526–2534.
   PubMed Web of Science ®Google Scholar
• Kundig, T.M., Bachmann, M.F., Oehen, S., Hoffmann, U.W., Simard, J.J., Kalberer, C.P., Pircher, H., Ohashi, P.S., Hengartner, H. and Zinkernagel, R.M. (1996) “On the role of antigen in maintaining cytotoxic T-cell memory”, Proc. Natl Acad. Sci. USA 93, 9716–9723.
   PubMed Web of Science ®Google Scholar
• Kwiatkowska, K. and Sobota, A. (1999) “Signaling pathways in phagocytosis”, Bioessays 21, 422–431.
   PubMed Web of Science ®Google Scholar
• Lee, T.C. (1998) “Biosynthesis and possible biological functions of plasmalogens”, Biochim. Biophys. Acta 1394, 129–145.
   PubMed Web of Science ®Google Scholar
• Mahon, B.P., Moore, A., Johnson, P.A. and Mills, K.H. (1998) “Approaches to new vaccines”, Crit. Rev. Biotechnol. 18, 257–282.
   Google Scholar
• Martin, M., Michalek, S.M. and Katz, J. (2003) “Role of innate immune factors in the adjuvant activity of monophosphoryl lipid A”, Infect. Immun. 71, 2498–2507.
   Google Scholar
• Medina, E. and Guzman, C.A. (2001) “Use of live bacterial vaccine vectors for antigen delivery: potential and limitations”, Vaccine 19, 1573–1580.
   Google Scholar
• Melief, C.J., Toes, R.E., Medema, J.P., van der Burg, S.H., Ossendorp, F. and Offringa, R. (2000) “Strategies for immunotherapy of cancer”, Adv. Immunol. 75, 235–282.
   Web of Science ®Google Scholar
• Miller, T.L. and Wolin, M.J. (1986) “Methanogens in human and animal intestinal tracts”, System. Appl. Microbiol. 7, 223–229.
   Google Scholar
• Moore, M.W., Carbone, F.R. and Bevan, M.J. (1988) “Introduction of soluble protein into the class I pathway of antigen processing and presentation”, Cell 54, 777–785.
   PubMed Web of Science ®Google Scholar
• Moron, V.G., Rueda, P., Sedlik, C. and Leclerc, C. (2003) “In vivo, dendritic cells can cross-present virus-like particles using an endosome-to-cytosol pathway”, J. Immunol. 171, 2242–2250.
   Web of Science ®Google Scholar
• Moskophidis, D., Lechner, F., Pircher, H. and Zinkernagel, R.M. (1993) “Virus persistence in acutely infected immunocompetent mice by exhaustion of antiviral cytotoxic effector T cells”, Nature 362, 758-761 [published erratum appears in Nature 1993 Jul 15; 364 (6434) 262].
   Google Scholar
• O’Hagan, D.T. (2001) “Recent developments in vaccine delivery systems”, Curr. Drug Targets. Infect. Disord. 1, 273–286.
   PubMedGoogle Scholar
• Omri, A., Agnew, B.J. and Patel, G.B. (2003) “Short-term repeated dose toxicity profile of archaeosomes administered to mice via intravenous and oral routes”, Int. J. Toxicol. 22, 9–23.
   Google Scholar
• Pamer, E. and Cresswell, P. (1998) “Mechanisms of MHC class I—restricted antigen processing”, Annu. Rev. Immunol. 16, 323-358. Patel, G.B., Omri, A., Deschatelets, L.A. and Sprott, G.D. (2002) “Safety of archaeosome adjuvants evaluated in a mouse model”, J. Liposome Res. 12, 353–372.
   Google Scholar
• Rodriguez, A., Regnault, A., Kleijmeer, M., Ricciardi-Castagnoli, P. and Amigorena, S. (1999) “Selective transport of internalized antigens to the cytosol for MHC class I presentation in dendritic cells”, Nat. Cell Biol. 1, 362–368.
   Web of Science ®Google Scholar
• Sad, S. and Krishnan, L. (2003) “Maintenance and attrition of T-cell memory”, Crit. Rev. Immunol. 23, 129–147.
   Google Scholar
• Shimada, H., Nemoto, N., Shida, Y., Oshima, T. and Yamagishi, A. (2002) “Complete polar lipid composition of Thermoplasma acidophilum HO-62 determined by high-performance liquid chro- matography with evaporative light-scattering detection”, J. Bacteriol. 184, 556–563.
   PubMed Web of Science ®Google Scholar
• Singh, M. and O’Hagan, D.T. (2002) “Recent advances in vaccine adjuvants”, Pharm. Res. 19, 715–728.
   Google Scholar
• Sprott, G.D. (1992) “Structures of archaeobacterial membrane lipids”, J. Bioenerg. Biomembr. 24, 555–566.
   PubMed Web of Science ®Google Scholar
• Sprott, G.D., Ekiel, I. and Dicaire, C. (1990) “Novel, acid-labile, hydroxydiether lipid cores in methanogenic bacteria”, J. Biol. Chem. 265, 13735–13740.
   Web of Science ®Google Scholar
• Sprott, G.D., Meloche, M. and Richards, J.C. (1991) “Proportions of diether, macrocyclic diether, and tetraether lipids in Methanococcus jannaschii grown at different temperatures”, J. Bacteriol. 173, 3907–3910.
   PubMed Web of Science ®Google Scholar
• Sprott, G.D., Dicaire, C.J. and Patel, G.B. (1994) “The ether lipids of Methanosarcina mazei and other Methanosarcina species, compared by fast atom bombardment mass spectometry”, Can. J. Microbiol. 40, 837–843.
   Web of Science ®Google Scholar
• Sprott, G.D., Dicaire, C.J., Fleming, L.P. and Patel, G.B. (1996) “Stability of liposomes prepared from archaeobacterial lipids and phospha- tidylcholine mixtures”, Cells Mater. 6, 143–155.
   Google Scholar
• Sprott, G.D., Tolson, D.L. and Patel, G.B. (1997) “Archaeosomes as novel antigen delivery systems”, FEMS Microbiol. Lett. 154, 17-22. Sprott, G.D., Brisson, J., Dicaire, C.J., Pelletier, A.K., Deschatelets, L.A., Krishnan, L. and Patel, G.B. (1999) “A structural comparison of the total polar lipids from the human archaea Methanobrevibacter smithii and Methanosphaera stadtmanae and its relevance to the adjuvant activities of their liposomes”, Biochim. Biophys. Acta 1440, 275–288.
   Web of Science ®Google Scholar
• Sprott, G.D., Larocque, S., Cadotte, N., Dicaire, C.J., McGee, M. and Brisson, J.R. (2003a) “Novel polar lipids of halophilic eubacterium Planococcus H8 and archaeon Haloferax volcanii”, Biochim. Biophys. Acta 1633, 179–188.
   PubMed Web of Science ®Google Scholar
• Sprott, G.D., Sad, S., Fleming, L.P., Dicaire, C., Patel, G.B. and Krishnan, L. (2003b) “Archaeosomes varying in lipid composition differ in receptor-mediated endocytosis and differentially adjuvant immune responses to entrapped antigen”, Archaea 1, 151–164.
   PubMedGoogle Scholar
• Swain, M., Brisson, J.R., Sprott, G.D., Cooper, F.P. and Patel, G.B. (1997) “Identification of beta-L-gulose as the sugar moiety of the main polar lipid Thermoplasma acidophilum”, Biochim. Biophys. Acta 1345, 56–64.
   PubMed Web of Science ®Google Scholar
• Takeuchi, O., Hoshino, K., Kawai, T., Sanjo, H., Takada, H., Ogawa, T., Takeda, K. and Akira, S. (1999) “Differential roles of TLR2 and TLR4 in recognition of gram-negative and gram-positive bacterial cell wall components”, Immunity 11, 443–451.
   PubMed Web of Science ®Google Scholar
• Tengerdy, R.P. and Lacetera, N.G. (1991) “Vitamin E adjuvant formulations in mice”, Vaccine 9, 204–206.
   PubMed Web of Science ®Google Scholar
• Wang, R.F. and Rosenberg, S.A. (1999) “Human tumor antigens for cancer vaccine development”, Immunol. Rev. 170, 85–100.
   Google Scholar
• Wherry, E.J., Puorro, K.A., Porgador, A. and Eisenlohr, L.C. (1999) “The induction of virus-specific CTL as a function of increasing epitope expression: responses rise steadily until excessively high levels of epitope are attained”, J. Immunol. 163, 3735–3745.
   Web of Science ®Google Scholar
• Zajac, A.J., Blattman, J.N., Murali, K.K., Sourdive, D.J., Suresh, M., Altman, J.D. and Ahmed, R. (1998) “Viral immune evasion due to persistence of activated T cells without effector function”, J. Exp. Med. 188, 2205–2213.
   PubMed Web of Science ®Google Scholar