Modified poly(propylene imine) dendrimers as effective transfection agents for catalytic DNA enzymes (DNAzymes)

References

• Bakker A, Floren W, Voeten J, Janssens B, Smets G, Wouters W, Janicot M. Automation of whole body imaging of GFP-expressing tumors in living animals. GIT Imaging Microscopy 2001; 03/2001: 52–54
   Google Scholar
• Bielinska A, Kukowska-Latallo JF, Johnson J, Tomalia DA, Baker JR, Jr. Regulation of in vitro gene expression using antisense oligonucleotides or antisense expression plasmids transfected using starburst PAMAM dendrimers. Nucleic Acids Res 1996; 24: 2176–2182
   PubMed Web of Science ®Google Scholar
• Bielinska AU, Chen C, Johnson J, Baker JR, Jr. DNA complexing with polyamidoamine dendrimers: Implications for transfection. Bioconjug Chem 1999; 10: 843–850
   PubMed Web of Science ®Google Scholar
• Bosman AW, Janssen HM, Meijer EW. About dendrimers: Structure, physical properties and applications. Chem Rev 1999; 99: 1665–1688
   PubMed Web of Science ®Google Scholar
• Bragonzi A, Boletta A, Biffi A, Muggia A, Sersale G, Cheng SH, Bordignon C, Assael BM, Conese M. Comparison between cationic polymers and lipids in mediating systemic gene delivery to the lungs. Gene Ther 1999; 6(12)1995–2004
   PubMed Web of Science ®Google Scholar
• Cheng H, Zhou R, Liu L, Du B, Zhuo R. Cyclic core dendrimer as a new kind of vector for gene transfer into mammalian cells. Genetica 2000; 108: 53–56
   PubMed Web of Science ®Google Scholar
• Choi J, Joo DK, Kim CH, Kim K, Park JS. Synthesis of a barbell-like triblock copolymer, poly(l-lysine) dendrimer-block-poly(ethylene glycol)-block-poly(l-lysine) dendrimer and its self-assembly with plasmid DNA. J Am Chem Soc 2000; 122: 474–480
   Web of Science ®Google Scholar
• De Brabander-van den Berg EMM, Meijer EW. Poly(propylene imine) dendrimers: Large scale synthesis by heterogenously catalyzed hydrogenations. Angew Chem Int Ed Engl 1993; 32: 1308–1311
   Web of Science ®Google Scholar
• Delong R, Stephenson K, Loftus T, Fisher M, Alahari S, Nolting A, Juliano RL. Characterization of complexes of oligonucleotides with polyamidoamine starburst dendrimers and effects on intracellular delivery. J Pharm Sci 1997; 86: 762–764
   PubMed Web of Science ®Google Scholar
• Duncan R, Malik N. Dendrimers: Biocompatibility and potential for delivery of anticancer agents. Proc Int Symp Control Release Bioact Mater 1996; 23: 105–106
   Google Scholar
• Elissen-Roman C, van Hest JCM, Baars MWPL, van Genderen MHP, Meijer EW. Amphiphilic block copolymers based on quaternized poly(propylene imine) dendrimers. PMSE 1997; 77: 145–146
   Google Scholar
• Esfand R, Tomalia DA. Poly(amidoamine) (PAMAM) dendrimers: From biomimicry to drug delivery and biomedical applications. Drug Discov Today 2001; 6: 427–436
   PubMed Web of Science ®Google Scholar
• Haensler J, Szoka FC, Jr. Polyamidoamine cascade polymers mediate efficient transfection of cells in culture. Bioconjug Chem 1993; 4: 372–379
   PubMed Web of Science ®Google Scholar
• Hollins AJ, Benboubetra M, Omidi Y, Zinselmeyer BH, Schatzlein AG, Uchegbu IF, Akhtar S. Evaluation of generation 2 and 3 poly(propylenimine) dendrimers for the potential cellular delivery of antisense oligonucleotides targeting the epidermal growth factor receptor. Pharm Res 2004; 21(3)458–466
   PubMed Web of Science ®Google Scholar
• Hong S, Bielinska AU, Mecke A, Keszler B, Beals JL, Shi X, Balogh L, Orr BG, Baker JR, Jr, Banaszak Holl MM. Interaction of poly(amidoamine) dendrimers with supported lipid bilayers and cells: Hole formation and the relation to transport. Bioconjug Chem 2004; 15: 774–782
   PubMed Web of Science ®Google Scholar
• Joester D, Losson M, Pugin R, Heinzelmann H, Walter E, Merkle HP, Diederich F. Amphiphilic dendrimers: Novel self-assembling vectors for efficient gene delivery. Angew Chem Int Ed Engl 2003; 42: 1486–1490
   PubMed Web of Science ®Google Scholar
• Kabanov VA, Sergeyev VG, Pyshkina OA, Zinchenko AA, Zezin AB, Joosten JGH, Brackman J, Yoshikawa K. Interpolyelectrolyte complexes formed by DNA and astramol poly(propylene imine) dendrimers. Macromolecules 2000; 33: 9587–9593
   Web of Science ®Google Scholar
• Kihara F, Arima H, Tsutsumi T, Hirayama F, Uekama K. In vitro and in vivo gene transfer by an optimized alpha-cyclodextrin conjugate with polyamidoamine dendrimer. Bioconjug Chem 2003; 14: 342–350
   PubMed Web of Science ®Google Scholar
• Kreider JL, Ford WT. Quaternary ammonium ion dendrimers from methylation of poly(propylene imine)s. J Polym Sci Part A: Polym Chem 2001; 39: 821–832
   Web of Science ®Google Scholar
• Kukowska-Latallo JF, Bielinska AU, Johnson J, Spindler R, Tomalia DA, Baker JR, Jr. Efficient transfer of genetic material into mammalian cells using Starburst polyamidoamine dendrimers. Proc Natl Acad Sci U S A 1996; 93: 4897–4902
   PubMed Web of Science ®Google Scholar
• Kuo JH, Jan MS, Chiu HW. Mechanism of cell death induced by cationic dendrimers in RAW 264.7 murine macrophage-like cells. J Pharm Pharmacol 2005; 57(4)489–495
   PubMed Web of Science ®Google Scholar
• Lee JH, Lim YB, Choi JS, Lee Y, Kim TI, Kim HJ, Yoon JK, Kim K, Park JS. Polyplexes assembled with internally quaternized PAMAM-OH dendrimer and plasmid DNA have a neutral surface and gene delivery potency. Bioconjug Chem 2003; 14: 1214–1221
   PubMed Web of Science ®Google Scholar
• Lim YB, Kim T, Lee JW, Kim SM, Kim HJ, Kim K, Park JS. Self-assembled ternary complex of cationic dendrimer, cucurbituril, and DNA: Noncovalent strategy in developing a gene delivery carrier. Bioconjug Chem 2002; 13(6)1181–1185
   PubMed Web of Science ®Google Scholar
• Liu M, Frechet JM. Designing dendrimers for drug delivery. Pharm Sci Technol Today 1999; 2: 393–401
   PubMedGoogle Scholar
• Liu M, Kono K, Frechet JM. Water soluble dendrimer polyethylene glycol star like conjugates as potential drug carriers. J Polym Sci Part A: Polym Chem 1999; 37: 3492–3503
   Web of Science ®Google Scholar
• Loup C, Zanta MA, Caminade AM, Majoral JP, Meunier B. Preperation of water-soluble cationic phosphorus-containing dendrimers as DNA transfecting agents. Chem Eur J 1999; 5: 3644–3650
   Web of Science ®Google Scholar
• Luo D, Haverstick K, Belcheva N, Han E, Saltzman WM. Polyethylene gylcol conjugated PAMAM dendrimer for biocompatible, high efficiency DNA delivery. Macromolecules 2002; 35: 3456–3462
   Web of Science ®Google Scholar
• Malik N, Wiwattanapatapee R, Klopsch R, Lorenz K, Frey H, Weener JW, Meijer EW, Paulus W, Duncan R. Dendrimers: Relationship between structure and biocompatibility in vitro, and preliminary studies on the biodistribution of 125I-labelled polyamidoamine dendrimers in vivo. J Control Release 2000; 65: 133–148
   PubMed Web of Science ®Google Scholar
• Ohasaki M, Okuda T, Wada A, Hirayama T, Niidome T, Aoyagi H. In vitro gene transfection using dendritic poly(l-lysine). Bioconjug Chem 2002; 13: 510–517
   PubMed Web of Science ®Google Scholar
• Omidi Y, Hollins AJ, Drayton RM, Akhtar S. Polypropylenimine dendrimer-induced gene expression changes: The effect of complexation with DNA, dendrimer generation and cell type. J Drug Target 2005; 13(7)431–443
   PubMed Web of Science ®Google Scholar
• Ottaviani MF, Furini F, Casini A, Turro NJ, Jockusch S, Tomalia DA, Messori L. Formation of supramolecular structures between DNA and starburst dendrimers studied by EPR, CD, UV and melting profiles. Macromolecules 2000; 33: 7842–7851
   Web of Science ®Google Scholar
• Pan Y, Ford WT. Dendrimers with both hydrophilic and hydrophobic chains at every end. Macromolecules 1999; 32: 5468–5470
   Web of Science ®Google Scholar
• Pan Y, Ford WT. Amphiphilic dendrimers with both octyl and triethylenoxy methyl ether chain ends. Macromolecules 2000; 33: 3731–3738
   Web of Science ®Google Scholar
• Patri AK, Majoros IJ, Baker JR. Dendritic polymer macromolecular carriers for drug delivery. Curr Opin Chem Biol 2002; 6: 466–471
   PubMed Web of Science ®Google Scholar
• Qin L, Pahud DR, Ding Y, Bielinska AU, Kukowska-Latallo JF, Baker JR, Jr, Bromberg JS. Efficient transfer of genes into murine cardiac grafts by Starburst polyamidoamine dendrimers. Hum Gene Ther 1998; 9: 553–560
   PubMed Web of Science ®Google Scholar
• Roberts JC, Bhalgat MK, Zera RT. Preliminary biological evaluation of polyamidoamine (PAMAM) Starburst dendrimers. J Biomed Mater Res 1996; 30: 53–65
   PubMed Web of Science ®Google Scholar
• Schatzlein AG, Zinselmeyer BH, Elouzi A, Dufes C, Chim YT, Roberts CJ, Davies MC, Munro A, Gray AI, Uchegbu IF. Preferential liver gene expression with polypropylenimine dendrimers. J Control Release 3 2005; 101(1–3)247–258
   PubMed Web of Science ®Google Scholar
• Schlüter DA. Chapter 12: The synthesis and characterization of dendritic molecules. Synthesis of polymers, materials science and technology series, HM Janssen, EW Meijer. Wiley-VCH Verlag GmbH, D-69469, Weinheim, Germany 1999
   Google Scholar
• Shah DS, Sakthivel T, Toth I, Florence AT, Wilderspin AF. DNA transfection and transfected cell viability using amphipathic asymmetric dendrimers. Int J Pharm 2000; 208: 41–48
   PubMed Web of Science ®Google Scholar
• Shchepinov MS, Udalova IA, Bridgman AJ, Southern EM. Oligonucleotide dendrimers: Synthesis and use as polylabelled DNA probes. Nucleic Acids Res 1997; 25: 4447–4454
   PubMed Web of Science ®Google Scholar
• Stiriba SE, Frey H, Haag R. Dendritic polymers in biomedical applications: From potential to clinical use in diagnostics and therapy. Angew Chem Int Ed 2002; 41: 1329–1334
   PubMed Web of Science ®Google Scholar
• Tan Y, Liu F, Li Z, Li S, Huang L. Sequential injection of cationic liposome and plasmid DNA effectively transfects the lung with minimal inflammatory toxicity. Mol Ther 2001; 5(1)673–682
   Google Scholar
• Tang MX, Szoka FC. The influence of polymer structure on the interactions of cationic polymers with DNA and morphology of the resulting complexes. Gene Ther 1997; 4: 823–832
   PubMed Web of Science ®Google Scholar
• Tang MX, Redemann CT, Szoka FC, Jr. In vitro gene delivery by degraded polyamidoamine dendrimers. Bioconjug Chem 1996; 7: 703–714
   PubMed Web of Science ®Google Scholar
• Thomas TP, Patri AK, Myc A, Myaing MT, Ye JY, Norris TB, Baker JR, Jr. In vitro targeting of synthesized antibody-conjugated dendrimer nanoparticles. Biomacromolecules 2004; 5: 2269–2274
   PubMed Web of Science ®Google Scholar
• Wu J, Zhou J, Qu F, Bao P, Zhang Y, Peng L. Polycationic dendrimers interact with RNA molecules: Polyamine dendrimers inhibit the catalytic activity of Candida ribozymes. Chem Commun (Camb) 2005; 313–315
   PubMed Web of Science ®Google Scholar
• Wörner C, Mülhaupt R. Polynitrile- and polyamine-functional poly(trimethylene imine) dendrimers. Angew Chem Int Ed Engl 1993; 32: 1306–1308
   Web of Science ®Google Scholar
• Yoo H, Sazani P, Juliano RL. PAMAM dendrimers as delivery agents for antisense oligonucleotides. Pharm Res 1999; 16: 1799–1804
   PubMed Web of Science ®Google Scholar
• Zinselmeyer BH, Mackay SP, Schatzlein AG, Uchegbu IF. The lower-generation polypropylenimine dendrimers are effective gene-transfer agents. Pharm Res 2002; 19: 960–967
   PubMed Web of Science ®Google Scholar