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Research Article

Anionic LPD complexes for gene delivery to macrophage: Preparation, characterization and transfection in vitro

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Pages 668-678 | Received 06 Mar 2008, Accepted 14 May 2008, Published online: 03 Dec 2008

References

  • F Ahsan, IP Rivas, MA Khan, and AI Torres Suarez. 2002. Targeting to macrophages: Role of physicochemical properties of particulate carriers-liposomes and microspheres-on the phagocytosis by macrophages. J Control Release 79:29–40.
  • Y Aramaki, S Takano, and S Tsuchiya. 2001. Cationic liposomes induce macrophage apoptosis through mitochondrial pathway. Arch Biochem Biophys 392:245–250.
  • MA Arangoa, N Duzgunes, and C Tros de Ilarduya. 2003. Increased receptor-mediated gene delivery to the liver by protamine-enhanced–asialofetuin–lipoplexes. Gene Ther 10:5–14.
  • JC Birchall, IW Kellaway, and M Gumbleton. 2000. Physical stability and in vitro gene expression efficiency of nebulised lipid–peptide–DNA complexes. Int J Pharm 197:221–231.
  • MC De Oliveira, V Boutet, E Fattal, D Boquet, JM Grognet, P Couvreur, and JR Deverre. 2000. Improvement of in vivo stability of phosphodiester oligonucleotide using anionic liposomes in mice. Life Sci 67:1625–1637.
  • S Dokka, D Toledo, X Shi, J Ye, and Y Rojanasakul. 2000. High-efficiency gene transfection of macrophages by lipoplexes. Int J Pharm 206:97–104.
  • P Fillion, A Desjardins, K Sayasith, and J Lagace. 2001. Encapsulation of DNA in negatively charged liposomes and inhibition of bacterial gene expression with fluid liposome-encapsulated antisense oligonucleotides. Biochim Biophys Acta 1515:44–54.
  • M Gonzalez Ferreiro, LG Tillman, G Hardee, and R Bodmeier. 2002. Alginate/poly-l-lysine microparticles for the intestinal delivery of antisense oligonucleotides. Pharm Res 19:755–764.
  • M Gonzalez Ferreiro, RM Crooke, L Tillman, G Hardee, and R Bodmeier. 2003. Stability of polycationic complexes of an antisense oligonucleotide in rat small intestine homogenates. Eur J Pharm Biopharm 55:19–26.
  • IM Hafez, and PR Cullis. 2001. Roles of lipid polymorphism in intracellular delivery. Adv Drug Deliv Rev 47:139–148.
  • US Huth, R Schubert, and R Peschka-Suss. 2006. Investigating the uptake and intracellular fate of pH-sensitive liposomes by flow cytometry and spectral bio-imaging. J Control Release 110:490–504.
  • S Iwaoka, T Nakamura, S Takano, S Tsuchiya, and Y Aramaki. 2006. Cationic liposomes induce apoptosis through p38 MAP kinase-caspase-8-Bid pathway in macrophage-like RAW264.7 cells. J Leukoc Biol 79:184–191.
  • M Junghans, SM Loitsch, SC Steiniger, J Kreuter, and A Zimmer. 2005. Cationic lipid–protamine–DNA (LPD) complexes for delivery of antisense c-myc oligonucleotides. Eur J Pharm Biopharm 60:287–294.
  • HH Kim, WS Lee, JM Yang, and S Shin. 2003. Basic peptide system for efficient delivery of foreign genes. Biochim Biophys Acta 1640:129–136.
  • TI Kim, JU Baek, C Zhe Bai, and JS Park. 2007. Arginine-conjugated polypropylenimine dendrimer as a non-toxic and efficient gene delivery carrier. Biomaterials 28:2061–2067.
  • S Li, and L Huang. 1997. In vivo gene transfer via intravenous administration of cationic lipid–protamine–DNA (LPD) complexes. Gene Ther 4:891–900.
  • S Li, MA Rizzo, S Bhattacharya, and L Huang. 1998. Characterization of cationic lipid–protamine–DNA (LPD) complexes for intravenous gene delivery. Gene Ther 5:930–937.
  • E Liang, MN Rosenblatt, PS Ajmani, and JA Hughes. 2000. Biodegradable pH-sensitive surfactants (BPS) in liposome-mediated nucleic acid cellular uptake and distribution. Eur J Pharm Sci 11:199–205.
  • D Lochmann, E Jauk, and A Zimmer. 2004. Drug delivery of oligonucleotides by peptides. Eur J Pharm Biopharm 58:237–251.
  • W Martinet, GR De Meyer, JP Timmermans, AG Herman, and MM Kockx. 2006. Macrophages but not smooth muscle cells undergo benzyloxycarbonyl-Val-Ala-DL-Asp(O-methyl)-fluoromethylketone-induced nonapoptotic cell death depending on receptor-interacting protein 1 expression: Implications for the stabilization of macrophage-rich atherosclerotic plaques. J Pharmacol Exp Ther 317:1356–1364.
  • T Masuda, H Akita, and H Harashima. 2005. Evaluation of nuclear transfer and transcription of plasmid DNA condensed with protamine by microinjection: The use of a nuclear transfer score. FEBS Lett 579:2143–2148.
  • SM Moghimi, AC Hunter, and JC Murray. 2001. Long-circulating and target-specific nanoparticles: Theory to practice. Pharmacol Rev 53:283–318.
  • MR Mozafari, CJ Reed, and C Rostron. 2007. Prospects of anionic nanolipoplexes in nanotherapy: Transmission electron microscopy and light scattering studies. Micron 38:787–795.
  • N Ohmori, T Niidome, T Kiyota, S Lee, G Sugihara, A Wada, T Hirayama, and H Aoyagi. 1998. Importance of hydrophobic region in amphiphilic structures of alpha-helical peptides for their gene transfer-ability into cells. Biochem Biophys Res Commun 245:259–265.
  • N Parameswaran, CS Pao, KS Leonhard, DS Kang, M Kratz, SC Ley, and JL Benovic. 2006. Arrestin-2 and G protein-coupled receptor kinase 5 interact with NFkappaB1 p105 and negatively regulate lipopolysaccharide-stimulated ERK1/2 activation in macrophages. J Biol Chem 281:34159–34170.
  • SD Patil, DG Rhodes, and DJ Burgess. 2004. Anionic liposomal delivery system for DNA transfection. AAPS J 6:e29.
  • E Roux, M Francis, FM Winnik, and JC Leroux. 2002. Polymer based pH-sensitive carriers as a means to improve the cytoplasmic delivery of drugs. Int J Pharm 242:25–36.
  • A Ruhland, N Leal, and PE Kima. 2007. Leishmania promastigotes activate PI3K/Akt signalling to confer host cell resistance to apoptosis. Cell Microbiol 9:84–96.
  • M Ruponen, P Honkakoski, S Ronkko, J Pelkonen, M Tammi, and A Urtti. 2003. Extracellular and intracellular barriers in non-viral gene delivery. J Control Release 93:213–217.
  • G Shi, W Guo, SM Stephenson, and RJ Lee. 2002. Efficient intracellular drug and gene delivery using folate receptor-targeted pH-sensitive liposomes composed of cationic/anionic lipid combinations. J Control Release 80:309–319.
  • S Simoes, V Slepushkin, N Duzgunes, and MC Pedroso de Lima. 2001. On the mechanisms of internalization and intracellular delivery mediated by pH-sensitive liposomes. Biochim Biophys Acta 1515:23–37.
  • FL Sorgi, S Bhattacharya, and L Huang. 1997. Protamine sulfate enhances lipid-mediated gene transfer. Gene Ther 4:961–968.
  • R Tachibana, H Harashima, M Shono, M Azumano, M Niwa, S Futaki, and H Kiwada. 1998. Intracellular regulation of macromolecules using pH-sensitive liposomes and nuclear localization signal: Qualitative and quantitative evaluation of intracellular trafficking. Biochem Biophys Res Commun 251:538–544.
  • VP Torchilin. 2000. Drug targeting. Eur J Pharm Sci 11 (Suppl 2):S81–S91.
  • C Tros de Ilarduya, MA Arangoa, MJ Moreno-Aliaga, and N Duzgunes. 2002. Enhanced gene delivery in vitro and in vivo by improved transferrin-lipoplexes. Biochim Biophys Acta 1561:209–221.
  • L Wasungu, and D Hoekstra. 2006. Cationic lipids, lipoplexes and intracellular delivery of genes. J Control Release 116:255–264.
  • C Welz, W Neuhuber, H Schreier, M Metzler, R Repp, W Rascher, and A Fahr. 2000a. Nuclear transport of oligonucleotides in HepG2-cells mediated by protamine sulfate and negatively charged liposomes. Pharm Res 17:1206–1211.
  • C Welz, W Neuhuber, H Schreier, R Repp, W Rascher, and A Fahr. 2000b. Nuclear gene targeting using negatively charged liposomes. Int J Pharm 196:251–252.
  • I Yamane, M Nishikawa, and Y Takakura. 2005. Cellular uptake and activation characteristics of naked plasmid DNA and its cationic liposome complex in human macrophages. Int J Pharm 305:145–153.

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