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Endothelium
Journal of Endothelial Cell Research
Volume 15, 2008 - Issue 4
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Regular Articles

Liver Sinusoidal Endothelial Cells as Possible Vehicles for Gene Therapy: A Comparison Between Plasmid-Based and Lentiviral Gene Transfer Techniques

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Pages 165-173 | Received 15 Aug 2007, Accepted 29 Apr 2008, Published online: 13 Jul 2009

REFERENCES

  • Benten D., Follenzi A., Bhargava K. K., Kumaran V., Palestro C. J., Gupta S. Hepatic targeting of transplanted liver sinusoidal endothelial cells in intact mice. Hepatology 2005; 42: 140–148
  • Berg M., Wingender G., Djandji D., Hegenbarth S., Momburg F., Hammerling G., Limmer A., Knolle P. Cross-presentation of antigens from apoptotic tumor cells by liver sinusoidal endothelial cells leads to tumor-specific CD8+ T cell tolerance. European Journal of Immunology 2006; 36: 2960–2970
  • Braet F., Wisse E. Structural and functional aspects of liver sinusoidal endothelial cell fenestrae: A review. Comparative Hepatology 2002; 1: 1
  • Cardier J. E., Barbera-Guillem E. Extramedullary hematopoiesis in the adult mouse liver is associated with specific hepatic sinusoidal endothelial cells. Hepatology 1997; 26: 165–175
  • Diehl L., Schurich A., Grochtmann R., Hegenbarth S., Chen L., Knolle P. A. Tolerogenic maturation of liver sinusoidal endothelial cells promotes B7-homolog 1-dependent CD8+ T cell tolerance. Hepatology 2008; 47: 296–305
  • Do H., Healey J. F., Waller E. K., Lollar P. Expression of factor VIII by murine liver sinusoidal endothelial cells. Journal of Biological Chemistry 1999; 274: 19587–19592
  • Dobbs B. R., Rogers G. W., Xing H. Y., Fraser R. Endotoxin-induced defenestration of the hepatic sinusoidal endothelium: A factor in the pathogenesis of cirrhosis?. Liver 1994; 14: 230–233
  • Elvevold K. H., Nedredal G. I., Revhaug A., Smedsrod B. Scavenger properties of cultivated pig liver endothelial cells. Comparative Hepatology 2004; 3: 4
  • Fraser R., Dobbs B. R., Rogers G. W. Lipoproteins and the liver sieve: The role of the fenestrated sinusoidal endothelium in lipoprotein metabolism, atherosclerosis, and cirrhosis. Hepatology 1995; 21: 863–874
  • Hernandez J. L., Coll T., Ciudad C. J. A highly efficient electroporation method for the transfection of endothelial cells. Angiogenesis 2004; 7: 235–241
  • Knolle P. A., Limmer A. Neighborhood politics: The immunoregulatory function of organ-resident liver endothelial cells. Trends in Immunology 2001; 22: 432–437
  • Kumaran V., Benten D., Follenzi A., Joseph B., Sarkar R., Gupta S. Transplantation of endothelial cells corrects the phenotype in hemophilia A mice. Journal of Thrombosis and Haemostasis 2005; 3: 2022–2031
  • Limmer A., Ohl J., Wingender G., Berg M., Jungerkes F., Schumak B., Djandji D., Scholz K., Klevenz A., Hegenbarth S., Momburg F., Hammerling G. J., Arnold B., Knolle P. A. Cross-presentation of oral antigens by liver sinusoidal endothelial cells leads to CD8 T cell tolerance. European Journal of Immunology 2005; 35: 2970–2981
  • Martin S. G., Murray J. C. Gene-transfer systems for human endothelial cells. Advanced Drug Delivery Reviews 2000; 41: 223–233
  • Mendoza L., Olaso E., Anasagasti M. J., Fuentes A. M., Vidal-Vanaclocha F. Mannose receptor-mediated endothelial cell activation contributes to B16 melanoma cell adhesion and metastasis in liver. Journal of Cellular Physiology 1998; 174: 322–330
  • Mori T., Okanoue T., Sawa Y., Hori N., Ohta M., Kagawa K. Defenestration of the sinusoidal endothelial cell in a rat model of cirrhosis. Hepatology 1993; 17: 891–897
  • Mostoslavsky G., Kotton D. N., Fabian A. J., Gray J. T., Lee J. S., Mulligan R. C. Efficiency of transduction of highly purified murine hematopoietic stem cells by lentiviral and oncoretroviral vectors under conditions of minimal in vitro manipulation. Molecular Therapy 2005; 11: 932–940
  • Paez J., Montano R., Benatuil L., Iacomini J., Cardier J. E. High efficiency and long-term foreign gene expression in cultured liver sinusoidal endothelial cells by retroviral transduction. Endothelium 2006; 13: 279–285
  • Schmitz V., Qian C., Ruiz J., Sangro B., Melero I., Mazzolini G., Narvaiza I., Prieto J. Gene therapy for liver diseases: Recent strategies for treatment of viral hepatitis and liver malignancies. Gut 2002; 50: 130–135
  • Segura I., Gonzalez M. A., Serrano A., Abad J. L., Bernad A., Riese H. H. High transfection efficiency of human umbilical vein endothelial cells using an optimized calcium phosphate method. Analytical Biochemistry 2001; 296: 143–147
  • Siemering K. R., Golbik R., Sever R., Haseloff J. Mutations that suppress the thermosensitivity of green fluorescent protein. Current Biology 1996; 6: 1653–1663
  • Vidal-Vanaclocha F., Alonso-Varona A., Ayala R., Barbera-Guillem E. Functional variations in liver tissue during the implantation process of metastatic tumour cells. Virchows Archives A: Pathological Anatomy and Histopathology 1990; 416: 189–195
  • Wack K. E., Ross M. A., Zegarra V., Sysko L. R., Watkins S. C., Stolz D. B. Sinusoidal ultrastructure evaluated during the revascularization of regenerating rat liver. Hepatology 2001; 33: 363–378
  • Wattiaux R., Laurent N., Wattiaux-De Coninck S., Jadot M. Endosomes, lysosomes: Their implication in gene transfer. Advanced Drug Delivery Reviews 2000; 41: 201–208
  • Yokomori H., Oda M., Ogi M., Sakai K., Ishii H. Enhanced expression of endothelial nitric oxide synthase and caveolin-1 in human cirrhosis. Liver 2002; 22: 150–158

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