140
Views
2
CrossRef citations to date
0
Altmetric
Research Article

The regulatory effect of bromocriptine on cardiac hypertrophy by prolactin and D2 receptor modulation

, ORCID Icon, , &
Pages 675-679 | Received 14 Apr 2020, Accepted 18 May 2020, Published online: 01 Jun 2020

References

  • Maron BJ , Maron MS. Hypertrophic cardiomyopathy. Lancet. 2013;19(381):242–55.
  • Shah M .Hypertrophic cardiomyopathy. Cardiol Young. 2017;27(S1):S25–S30. doi:10.1017/S1047951116002195.
  • Zhao W , Zhao T , Chen Y , Zhao F , Gu Q , Williams RW , Bhattacharya SK , Lu L , Sun Y .A murine hypertrophic cardiomyopathy model: the DBA/2J strain. PLoS One. 2015;10(8):e0133132. doi:10.1371/journal.pone.0133132.
  • Liebson PR .Clinical studies of drug reversal of hypertensive left ventricular hypertrophy. Am J Hypertens. 1990;3(6 Pt 1):512–17. doi:10.1093/ajh/3.6.512.
  • Dhalla NS , Rangi S , Babick AP , Zieroth S , Elimban V .Cardiac remodeling and subcellular defects in heart failure due to myocardial infarction and aging. Heart Fail Rev. 2012;17(45):671–81. doi:10.1007/s10741-011-9278-7.
  • Heineke J , Molkentin JD .Regulation of cardiac hypertrophy by intracellular signalling pathways. Nat Rev Mol Cell Biol. 2006;7(8):589–600. doi:10.1038/nrm1983.
  • Yang CM , Kandaswamy V , Young D , Sen S .Changes in collagen phenotypes during progression and regression of cardiac hypertrophy. Cardiovasc Res. 1997;36(2):236–45. doi:10.1016/S0008-6363(97)00186-7.
  • Sharma R , Coats AJ , Anker SD .The role of inflammatory mediators in chronic heart failure: cytokines, nitric oxide, and endothelin-1. Int J Cardiol. 2000;72(2):175–86. doi:10.1016/S0167-5273(99)00186-2.
  • Rathore HA , Munavvar AS , Abdullah NA , Khan AH , Fathihah B , NurJannah MH , Raisa NA , Anand Swarup KRL , Abdullah MH , Salman IM , et al. Interaction between renin-angiotensin and sympathetic nervous systems in a rat model of pressure overload cardiac hypertrophy. Auton Autacoid Pharmacol. 2009;29(4):171–80. doi:10.1111/j.1474-8665.2009.00445.x.
  • Zhao M , Fajardo G , Urashima T , Spin JM , Poorfarahani S , Rajagopalan V , Huynh D , Connolly A , Quertermous T , Bernstein D , et al. Cardiac pressure overload hypertrophy is differentially regulated by beta-adrenergic receptor subtypes. Am J Physiol Heart Circ Physiol. 2011;301(4):H1461H1470. doi:10.1152/ajpheart.00453.2010.
  • Lin Y , Wang LN , Xi YH , Li H-Z , Xiao F-G , Zhao Y-J , Tian Y , Yang B-F , Xu C-Q , et al. L-arginine inhibits isoproterenol-induced cardiac hypertrophy through nitric oxide and polyamine pathways. Basic Clin Pharmacol Toxicol. 2008;103(2):124–30. doi:10.1111/j.1742-7843.2008.00261.x.
  • Bupha-Intr T , Haizlip KM , Janssen PM .Role of endothelin in the induction of cardiac hypertrophy in vitro. PLoS One. 2012;7(8):e43179. doi:10.1371/journal.pone.0043179.
  • Maulik SK , Kumar S .Oxidative stress and cardiac hypertrophy: a review. Toxicol Mech Methods. 2012;22(5):359–66. doi:10.3109/15376516.2012.666650.
  • Wang GJ , Wang HX , Yao YS , Guo LY , Liu P .The role of Ca(2)+/calmodulin-dependent protein kinase II and calcineurin in TNF-alpha-induced myocardial hypertrophy. Braz J Med Biol Res. 2012;45(11):1045–51. doi:10.1590/S0100-879X2012007500121.
  • Diaz JA , Booth AJ , Lu G , Wood SC , Pinsky DJ , Bishop DK .Critical role for IL-6 in hypertrophy and fibrosis in chronic cardiac allograft rejection. Am J Transplant. 2009;9(8):1773–83. doi:10.1111/j.1600-6143.2009.02706.x.
  • Reda E , Hassaneen S , El-Abhar HS . Novel Trajectories of bromocriptine antidiabetic action: leptin-IL-6/JAK2/p-STAT3/SOCS3, p-IR/p-AKT/GLUT4, PPAR-γ/Adiponectin, Nrf2/PARP-1, and GLP-1. Front Pharmacol. 2018;18:771. doi:10.3389/fphar.2018.00771.
  • Ding HS , Yang J , Ding JW , Chen P , Zhu P .Interleukin-17 contributes to cardiovascular diseases. Mol Biol Rep. 2012;39(7):7473–78. doi:10.1007/s11033-012-1580-5.
  • Defronzo RA .Bromocriptine: a sympatholytic, d2-dopamine agonist for the treatment of type 2 diabetes. Diabetes Care. 2011;34(4):789–94. doi:10.2337/dc11-0064.
  • Ezrokhi M , Luo S , Trubitsyna Y , Cincotta AH . Weighted effects of bromocriptine treatment on glucose homeostasis during hyperglycemic versus euglycemic clamp conditions in insulin resistant hamsters: bromocriptine as a unique postprandial insulin sensitizer. J Diabetes Metab. 2012;S2:007. doi:10.4172/2155-6156.S2-007.
  • Mejia-Rodriguez O , Alvarez-Aguilar C , Vega-Gomez HE , Belio-Caro F , Vargas-Espinosa JM , Paniagua-Sierra JR . Bromocriptine induces regression of left ventricular hypertrophy in peritoneal dialysis patients. Proc West Pharmacol Soc. 2005;48:122–25.
  • Ried K , Frank OR , Stocks NP , Fakler P , Sullivan T .Effect of garlic on blood pressure: a systematic review and meta-analysis. BMC Cardiovasc Disord. 2008;8(1):13. doi:10.1186/1471-2261-8-13.
  • Nakagawa H , Tsuta K , Kiuchi K , et al. Growth inhibitory effects of diallyl disulfide on human breast cancer cell lines. Carcinogenesis. 2001;22(6):891–97. doi:10.1093/carcin/22.6.891.
  • Colin-Gonzalez AL , Santana RA , Silva-Islas CA , Chanez-Cardenas ME , Santamaria A , Maldonado PD . The antioxidant mechanisms underlying the aged garlic extract- and S-allylcysteine-induced protection. Oxid Med Cell Longev. 2012;2012:16. doi:10.1155/2012/907162.
  • Thomson M , Al-Qattan KK , Bordia T , Ali M .Including garlic in the diet may help lower blood glucose, cholesterol, and triglycerides. J Nutr. 2006;136(3):800S–802S. doi:10.1093/jn/136.3.800S.
  • Hilfiker-Kleiner D , Meyer GP , Schieffer E , Goldmann B , Podewski E , Struman I , Fischer P , Drexler H , et al. Recovery from postpartum cardiomyopathy in 2 patients by blocking prolactin release with bromocriptine. J Am Coll Cardiol. 2007;50(24):2354–55. doi:10.1016/j.jacc.2007.10.006.
  • Meyer GP , Labidi S , Podewski E , Sliwa K , Drexler H , Hilfiker-Kleiner D .Bromocriptine treatment associated with recovery from peripartum cardiomyopathy in siblings: two case reports. J Med Case Rep. 2010;4(1):80. doi:10.1186/1752-1947-4-80.
  • Triebel J , Robles-Osorio ML , Garcia-Franco R , Martínez de la Escalera G , Clapp C , Bertsch T . From Bench to Bedside: translating the Prolactin/Vasoinhibin Axis. Front Endocrinol Lausanne. 2017 11;8: 342. doi:10.3389/fendo.2017.00342.
  • McDonald WM , Sibley DR , Kilpatrick BF , Caron MG .Dopaminergic inhibition of adenylate cyclase correlates with high affinity agonist binding to anterior pituitary D2 dopamine receptors. Mol Cell Endocrinol. 1984;36(3):201–09. doi:10.1016/0303-7207(84)90037-6.
  • George SR , Watanabe M , Di Paolo T , Falardeau P , Labrie F , Seeman P . The functional state of the dopamine receptor in the anterior pituitary is in the high affinity form. Endocrinology. 1985;117:690−697.
  • Durdagi S , Salmas RE , Stein M , Yurtsever M , Seeman P .Binding interactions of dopamine and apomorphine in D2 high and D2 low states of human dopamine D2 receptor using computational and experimental techniques. ACS Chem Neurosci. 2016;17(2):185–95. doi:10.1021/acschemneuro.5b00271.
  • JF T , Schennink A , WK P , Manjarin R , VanKlompenberg MK , Hovey RC .Triennial lactation symposium: prolactin: the multifaceted potentiator of mammary growth and function. J Anim Sci. 2012;90(5):1674–86. doi:10.2527/jas.2011-4682.
  • Helmer RA , Panchoo M , Dertien JS , Bhakta SM , Hewetson A , Chilton BS .Prolactin-induced Jak2 phosphorylation of RUSH: a key element in Jak/RUSH signaling. Mol Cell Endocrinol. 2010;325(12):143–49. doi:10.1016/j.mce.2010.05.010.
  • Limas CJ , Kroupis C , Haidaroglou A , Cokkinos DV . 2002. Hyperprolactinaemia in patients with heart failure: clinical and immunogenetic correlations. Eur J Clin Invest. 32(2):74‐78. doi:10.1046/j.1365-2362.2002.00924.x
  • Haring R , Völzke H , Vasan RS , et al. Sex-specific associations of serum prolactin concentrations with cardiac remodeling: longitudinal results from the study of health pomerania (SHIP). Atherosclerosis. 2012;221(2):570‐576. doi:10.1016/j.atherosclerosis.2012.01.017.
  • El-Eshmawy MM , Elkhamisy EM , Elsayed E , Kamal S . 2017. Impact of gender on the association between low serum prolactin and left ventricular mass in subjects with prediabetes. Diabetes Metab J. 41(3):195‐204. doi:10.4093/dmj.2017.41.3.195
  • Helmer RA , Dertien JS , Chilton BS .Prolactin induces Jak2 phosphorylation of RUSHY195. Mol Cell Endocrinol. 2011;338(12):79–83. doi:10.1016/j.mce.2011.03.009.
  • Abassi Z , Goltsman L , Karram T , Winaver J , Hoffman A . Aortocaval fistula in rat: a unique model of volume-overload congestive heart failure and cardiac hypertrophy. J Biomed Biotechnol. 2011;13.2011;2011:729497
  • Stumpe KO , Solle H , Solle KH , Kruck F .Mechanism of sodium and water retention in rats with experimental heart failure. Kidney Int. 1973;4(5):309–17. doi:10.1038/ki.1973.122.
  • Brodsky S , Gurbanov K , Abassi Z .Effects of eprosartan on renal function and cardiac hypertrophy in rats with experimental heart failure. Hypertension. 1998;32(4):746–52. doi:10.1161/01.HYP.32.4.746.
  • Rosenthal DS , Braunwald E . Hematological-oncological disorders and heart disease. In: Braunwald E , editor. Heart disease. A textbook of cardiovascular medicine. Philadelphia, PA: Saunders; 1992. p. 1742–66.
  • Fioretto JR , Querioz SS , Padovani CR , Matsubara LS , Okoshi K , Matsubara BB .Ventricular remodeling and diastolic myocardial dysfunction in rats submitted to protein-calorie malnutrition. Am J Physiol Heart Circ Physiol. 2002;282(4):H1327H33. doi:10.1152/ajpheart.00431.2001.
  • Martínez S , Efrén L . Fisisopatología de la falla vetricular derechas en la hipertension arterial pulmonar. Instituto Nacional de Cradiología Ignacio Chávez. 2004;74:353–57.
  • Jiang XB , Zhang J , Li CL , Mao ZG , Hu B , Zhu Z , Zhu YH , Wang HJ .Subclinical impairment of left ventricular longitudinal function in patients with prolactinomas. Endocr Pract. 2017;23(12):1379–86. doi:10.4158/EP171985.OR.
  • Patel PA , Roy A , Javid R , Dalton JA .A contemporary review of peripartum cardiomyopathy. Clin Med (Lond). 2017;17(4):316–21. doi:10.7861/clinmedicine.17-4-316.
  • Kohli S , Ahuja S , Rani V .Transcription factors in heart: promising therapeutic targets in cardiac hypertrophy. Curr Cardiol Rev. 2011;7(4):262–71. doi:10.2174/157340311799960618.
  • Urbanek K , Quaini F , Tasca G , Torella D , Castaldo C , Nadal-Ginard B , Leri A , Kajstura J , Quaini E , Anversa P , et al. Intense myocyte formation from cardiac stem cells in human cardiac hypertrophy. Proc Natl Acad Sci U S A. 2003;100(18):10440–45. doi:10.1073/pnas.1832855100.
  • Hilfiker-Kleiner D , Haghikia A , Berliner D , Vogel-Claussen J , Schwab J , Franke A , Schwarzkopf M , Ehlermann P , Pfister R , Michels G , et al.Bromocriptine for the treatment of peripartum cardiomyopathy: a multicentre randomized study. Eur Heart J. 2017;38(35):2671–79. doi:10.1093/eurheartj/ehx355.
  • De Simone G , McClelland R , Gottdiener JS , Celentano A , Kronmal RA , Gardin JM .Relation of hemodynamics and risk factors to ventricular-vascular interactions in the elderly: the cardiovascular health study. J Hypertens. 2001;19(10):1893–903. doi:10.1097/00004872-200110000-00026.
  • Martín Pérez J. Fisiología de la Prolactina. Madrid (España): McGraw-Hill; 2010. p.16. https://digital.csic.es/handle/10261/78144
  • Francis GS , Parks R , Cohn JN .The effects of bromocriptine in patients with congestive heart failure. Am Heart J. 1983;106(1):100–06. doi:10.1016/0002-8703(83)90446-5.
  • Vellertri Pul BL , Barbara T .Effects of captopril on rat aortic angiotensin-converting enzyme. J Cardiovascular Pharmacol. 1982;4(4):315–25. doi:10.1097/00005344-198203000-00022.
  • Carvalho JC , Lisboa PC , de Oliveira E , Peixoto-Silva N , Nobre JL , Fraga MC , Manhães AC , Moura EG . Effects of postnatal bromocriptine injection on thyroid function and prolactinemia of rats at adulthood. Neuropeptides. 2016;59:71–81. doi:10.1016/j.npep.2016.05.003.
  • Pfeffer JM , Pfeffer MA , Mirsky I , Braunwald E .Regression of left ventricular hypertrophy and prevention of left ventricular dysfunction by captopril in the spontaneously hypertensive rat. Proc Natl Acad Sci U S A. 1982;79(10):3310–14. doi:10.1073/pnas.79.10.3310.
  • Koenig T , Hilfiker-Kleiner D , Bauersachs J . Bromocriptine for the Treatment of Peripartum Cardiomyopathy. Card Fail Rev. 2018;4(1):46‐49. doi:10.15420/cfr.2018:2:2
  • Li H , Shi S , Sun YH , Zhao YJ , Li QF , Li HZ , Wang R , Xu CQ . Dopamine D2 receptor stimulation inhibits angiotensin II-induced hypertrophy in cultured neonatal rat ventricular myocytes. Clin Exp Pharmacol Physiol. 2009;36(3):312–18. doi:10.1111/j.1440-1681.2008.05064.x

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.