131
Views
2
CrossRef citations to date
0
Altmetric
Research Article

The paradox of the role of resistin in early-onset obesity hypertension: A comparative study among four Chinese adult subgroups

, , , , , & show all
Pages 385-391 | Received 10 Nov 2020, Accepted 26 Jan 2021, Published online: 22 Mar 2021

References

  • Susic D, Obesity: VJ.A perspective from hypertension[J]. Med Clin North Am. 2017;101(1):139–57.
  • Nakamura K, J J F, Adipokines: WK.A link between obesity and cardiovascular disease[J]. J Cardiol. 2014;63(4):250–59.doi:10.1016/j.jjcc.2013.11.006.
  • Mostafazadeh M, Haiaty S, Rastqar A, et al. Correlation between resistin level and metabolic syndrome component: A review[J]. Horm Metab Res. 2018;50(7):521–36.doi:10.1055/a-0637-1975.
  • H K P, M K K, H J K, et al. Linking resistin, inflammation, and cardiometabolic diseases[J]. Korean J Intern Med. 2017;32(2):239–47.doi:10.3904/kjim.2016.229.
  • Badoer E, Kosari S, Stebbing MJ. Resistin, an adipokine with non-generalized actions on sympathetic nerve activity[J]. Front Physiol. 2015;6:321.doi:10.3389/fphys.2015.00321.
  • Kosari S, J A R, Chen F, et al. Centrally administered resistin enhances sympathetic nerve activity to the hindlimb but attenuates the activity to brown adipose tissue[J]. Endocrinology. 2011;152(7):2626–33.doi:10.1210/en.2010-1492.
  • Takata Y, Osawa H, Kurata M, et al. Hyperresistinemia is associated with coexistence of hypertension and type 2 diabetes[J]. Hypertension. 2008;51(2):534–39.doi:10.1161/HYPERTENSIONAHA.107.103077.
  • Thomopoulos C, Daskalaki M, Papazachou O, et al. Association of resistin and adiponectin with different clinical blood pressure phenotypes[J]. J Hum Hypertens. 2011;25(1):38–46.doi:10.1038/jhh.2010.22.
  • D P P, T K M, Perrea D, et al. Adiponectin–insulin and resistin plasma levels in young healthy offspring of patients with essential hypertension[J]. Blood Press. 2008;17(1):50–54.doi:10.1080/08037050701876307.
  • Zhang L, G C C, Forman JP.Plasma resistin levels associate with risk for hypertension among nondiabetic women[J]. J Am Soc Nephrol. 2010;21(7):1185–91.doi:10.1681/ASN.2009101053.
  • Gursoy G, Ulu S, Acar Y, et al. Relation of resistin with obesity and some cardiovascular risk factors in hypertensive women[J]. J Res Med Sci 2012;17:443–47.
  • M R S, H A C, W G E, et al. Relationships among insulin resistance, obesity, diagnosis of the metabolic syndrome and cardio-metabolic risk[J]. Diab Vasc Dis Res. 2011;8(2):109–16.doi:10.1177/1479164111403170.
  • O A M, Abdella NA.Associations of resistin with inflammation and insulin resistance in patients with type 2 diabetes mellitus[J]. Scand J Clin Lab Invest. 2007;67(2):215–25.doi:10.1080/00365510601032532.
  • C W Z, Y H G, W X S, et al. An update on the emerging role of resistin on the pathogenesis of osteoarthritis[J]. Mediators Inflamm. 2019;2019:1532164.
  • K G A, Zimmet PZ.Should we dump the metabolic syndrome? No[J]. BMJ. 2008;336(7645):641.doi:10.1136/bmj.39484.636586.94.
  • Kang YS.Obesity associated hypertension: new insights into mechanism[J]. Electrolyte Blood Press. 2013;11(2):46–52.doi:10.5049/EBP.2013.11.2.46.
  • Bokarewa M, Nagaev I, Dahlberg L, et al. Resistin, an adipokine with potent proinflammatory properties[J]. J Immunol. 2005;174(9):5789–95.doi:10.4049/jimmunol.174.9.5789.
  • Filkova M, Haluzik M, Gay S, et al. The role of resistin as a regulator of inflammation: implications for various human pathologies[J]. Clin Immunol. 2009;133(2):157–70.doi:10.1016/j.clim.2009.07.013.
  • Codoner-Franch P, Resistin: A-IE. Insulin resistance to malignancy[J]. Clin Chim Acta. 2015;438:46–54.doi:10.1016/j.cca.2014.07.043.
  • Silswal N, A K S, Aruna B, et al. Human resistin stimulates the pro-inflammatory cytokines tnf-alpha and il-12 in macrophages by nf-kappab-dependent pathway[J]. Biochem Biophys Res Commun. 2005;334(4):1092–101.doi:10.1016/j.bbrc.2005.06.202.
  • Kaser S, Kaser A, Sandhofer A, et al. Resistin messenger-rna expression is increased by proinflammatory cytokines in vitro[J]. Biochem Biophys Res Commun. 2003;309(2):286–90.doi:10.1016/j.bbrc.2003.07.003.
  • Tarkowski A, Bjersing J, Shestakov A, et al. Resistin competes with lipopolysaccharide for binding to toll-like receptor 4[J]. J Cell Mol Med. 2010;14(6B):1419–31.doi:10.1111/j.1582-4934.2009.00899.x.
  • Jiang Y, Lu L, Hu Y, et al. Resistin induces hypertension and insulin resistance in mice via a tlr4-dependent pathway[J]. Sci Rep. 2016;6:22193.
  • Verma S, S H L, C H W, et al. Resistin promotes endothelial cell activation: further evidence of adipokine-endothelial interaction[J]. Circulation. 2003;108(6):736–40.doi:10.1161/01.CIR.0000084503.91330.49.
  • Chen C, Jiang J, J M L, et al. Resistin decreases expression of endothelial nitric oxide synthase through oxidative stress in human coronary artery endothelial cells[J]. Am J Physiol Heart Circ Physiol. 2010;299(1):H193–201. doi:10.1152/ajpheart.00431.2009.
  • Sadashiv TS, B N P, et al. Resistin gene expression in visceral adipose tissue of postmenopausal women and its association with insulin resistance[J]. Womens Health (Lond). 2012;8(5):521–28.doi:10.2217/WHE.12.46.
  • Dominguez Coello S, Cabrera de Leon A, Almeida Gonzalez D, et al. Inverse association between serum resistin and insulin resistance in humans[J]. Diabetes Res Clin Pract. 2008;82(2):256–61.doi:10.1016/j.diabres.2008.08.001.
  • G P G, Provatopoulou X, Kalogera E, et al. Serum resistin is inversely related to breast cancer risk in premenopausal women[J]. Breast. 2016;29:163–69.
  • Tripathi D, Kant S, Pandey S, et al. Resistin in metabolism, inflammation, and disease[J]. Febs J. 2020;287(15):3141–49.doi:10.1111/febs.15322.
  • K Z S, Y R L, Zhang D, et al. Relation of circulating resistin to insulin resistance in type 2 diabetes and obesity: A systematic review and meta-analysis[J]. Front Physiol. 2019;10:1399.
  • Bajnok L, Seres I, Varga Z, et al. Relationship of serum resistin level to traits of metabolic syndrome and serum paraoxonase 1 activity in a population with a broad range of body mass index[J]. Exp Clin Endocrinol Diabetes. 2008;116(10):592–99.doi:10.1055/s-2008-1065350.
  • A V C, G L B, H R B, et al. The seventh report of the joint national committee on prevention, detection, evaluation, and treatment of high blood pressure: the jnc 7 report[J]. JAMA. 2003;289(19):2560–72.doi:10.1001/jama.289.19.2560.
  • S K W, Ma W, Wang S, et al. Obesity and its relationship with hypertension among adults 50 years and older in jinan, china[J]. PLoS One. 2014;9(12):e114424.doi:10.1371/journal.pone.0114424.
  • S T A, B M M, G D P, et al. Waist circumference is better associated with high density lipoprotein (hdl-c) than with body mass index (bmi) in adults with metabolic syndrome[J]. Nutr Hosp. 2011;26(6):1328–32.doi:10.1590/S0212-16112011000600020.
  • Chen C, F C L.Department of disease control ministry of health P R C. The Guidelines for Prevention and Control of Overweight and Obesity in Chinese adults[J] Biomed Environ Sci. 2004;17(Suppl):1–36.
  • Apovian CM.Obesity: definition, comorbidities, causes, and burden[J]. Am J Manag Care. 2016;22(7 Suppl):s176–185.
  • Lopatynski J, Mardarowicz G, Szczesniak G.A comparative evaluation of waist circumference, waist-to-hip ratio, waist-to-height ratio and body mass index as indicators of impaired glucose tolerance and as risk factors for type-2 diabetes mellitus[J]. Ann Univ Mariae Curie Sklodowska Med. 2003;58(1):413–19.
  • Wu O, J H L, F F Y, et al. A comparative research on obesity hypertension by the comparisons and associations between waist circumference, body mass index with systolic and diastolic blood pressure, and the clinical laboratory data between four special chinese adult groups[J]. Clin Exp Hypertens. 2018;40(1):16–21.doi:10.1080/10641963.2017.1281940.
  • P G M, C M K, Resistin[J] KS, Lipidol CO. 2006. Curr Opin Lipidol. 17(2): 170–75. DOI:10.1097/01.mol.0000217899.59820.9a
  • Acquarone E, Monacelli F, Borghi R, et al. Resistin: A reappraisal[J]. Mech Ageing Dev. 2019;178:46–63.
  • L L J, Li L, X F H, et al. Patients with nonalcoholic fatty liver disease display increased serum resistin levels and decreased adiponectin levels[J]. Eur J Gastroenterol Hepatol. 2009;21(6):662–66.doi:10.1097/MEG.0b013e328317f4b5.
  • C P R-L, M C G-T, Cruz-Bautista I, et al. Visceral obesity, skeletal muscle mass and resistin in metabolic syndrome development[J]. Nutr Hosp. 2019;36(1):43–50.doi:10.20960/nh.1889.
  • Zhang Y, Li Y, Yu L, et al. Association between serum resistin concentration and hypertension: A systematic review and meta-analysis[J]. Oncotarget. 2017;8(25):41529–37.doi:10.18632/oncotarget.17561.
  • Diakowska D, Markocka-Maczka K, Szelachowski P, et al. Serum levels of resistin, adiponectin, and apelin in gastroesophageal cancer patients[J]. Dis Markers. 2014;2014:619649.
  • Krecki R, Krzeminska-Pakula M, Drozdz J, et al. Relationship of serum angiogenin, adiponectin and resistin levels with biochemical risk factors and the angiographic severity of three-vessel coronary disease[J]. Cardiol J 2010;17:599–606.
  • Cabrera de Leon A, Almeida Gonzalez D, Gonzalez Hernandez A, et al. The association of resistin with coronary disease in the general population[J]. J Atheroscler Thromb. 2014;21(3):273–81.doi:10.5551/jat.19273.
  • D J W, Strand M, Rask E, et al. Intra-adipose sex steroid metabolism and body fat distribution in idiopathic human obesity[J]. Clin Endocrinol (Oxf). 2007;66(3):440–46.doi:10.1111/j.1365-2265.2007.02755.x.
  • R M W, Shiang T, Al Sayah L, et al. Arterial stiffening precedes systolic hypertension in diet-induced obesity[J]. Hypertension. 2013;62(6):1105–10.doi:10.1161/HYPERTENSIONAHA.113.01744.
  • B M K, Rong J, M G L, et al. Aortic stiffness, blood pressure progression, and incident hypertension[J]. JAMA. 2012;308(9):875–81.doi:10.1001/2012.jama.10503.
  • M E S, L M VB, Struijker-Boudier HA.Resistance and conduit arteries following converting enzyme inhibition in hypertension[J]. J Vasc Res. 1997;34(2):67–81.doi:10.1159/000159204.
  • Uchida H, Nakamura Y, Kaihara M, et al. Practical efficacy of telmisartan for decreasing morning home blood pressure and pulse wave velocity in patients with mild-to-moderate hypertension[J]. Hypertens Res. 2004;27(8):545–50.doi:10.1291/hypres.27.545.
  • Fujie S, Hasegawa N, Sato K, et al. Aerobic exercise training-induced changes in serum adropin level are associated with reduced arterial stiffness in middle-aged and older adults[J]. Am J Physiol Heart Circ Physiol. 2015;309(10):H1642–1647. doi:10.1152/ajpheart.00338.2015.
  • N W R, G A H, Kaye DM.Say no to obesity-related hypertension: role of the l-arginine-nitric oxide pathway[J]. Hypertension. 2016;67(5):813–19.doi:10.1161/HYPERTENSIONAHA.116.06778.
  • Roush GC.Obesity-induced hypertension: heavy on the accelerator[J]. J Am Heart Assoc. 2019;8(8):e012334.doi:10.1161/JAHA.119.012334.
  • A L C, Fernandes A, J A A-P, et al. Towards frailty biomarkers: candidates from genes and pathways regulated in aging and age-related diseases[J]. Ageing Res Rev. 2018;47:214–77.
  • K H K, Lee K, Y S M, et al. A cysteine-rich adipose tissue-specific secretory factor inhibits adipocyte differentiation[J]. J Biol Chem. 2001;276(14):11252–56.doi:10.1074/jbc.C100028200.
  • C M S, Lazar MA.The current biology of resistin[J]. J Intern Med. 2004;255(4):439–47.doi:10.1111/j.1365-2796.2004.01306.x.
  • J E H, Do Carmo JM, da Silva AA, et al. Obesity-induced hypertension: interaction of neurohumoral and renal mechanisms[J]. Circ Res. 2015;116(6):991–1006.doi:10.1161/CIRCRESAHA.116.305697.
  • Zhang M, Cui H, B P Z, et al. Association of serum resistin with cystatin c and urinary albumin-to-creatinine ratio in elderly chinese men with essential hypertension[J]. Postgrad Med J. 2015;91(1073):132–37.doi:10.1136/postgradmedj-2013-132408.
  • Joksic J, Sopic M, Spasojevic-Kalimanovska V, et al. Circulating resistin protein and mrna concentrations and clinical severity of coronary artery disease[J]. Biochem Med (Zagreb). 2015;25(2):242–51.doi:10.11613/BM.2015.025.
  • Dimitriadis K, Tsioufis C, Selima M, et al. Independent association of circulating resistin with glomerular filtration rate in the early stages of essential hypertension[J]. J Hum Hypertens. 2009;23(10):668–73.doi:10.1038/jhh.2009.12.
  • Marouga A, Dalamaga M, A N K, et al. Correlates of serum resistin in elderly, non-diabetic patients with chronic kidney disease[J]. Clin Lab. 2013;59(9–10):1121–28. doi:10.7754/Clin.Lab.2012.121112.
  • Zhou L, Yu X, Meng Q, et al. Resistin reduces mitochondria and induces hepatic steatosis in mice by the protein kinase c/protein kinase g/p65/ppar gamma coactivator 1 alpha pathway[J]. Hepatology. 2013;57(4):1384–93.doi:10.1002/hep.26167.
  • A A B, Lokhandwala MF.Renal dopamine oxidation and inflammation in high salt fed rats[J]. J Am Heart Assoc. 2020;9(1):e014977.doi:10.1161/JAHA.119.014977.
  • Ackermann A, M S F-A, Sanchez de Rojas R, et al. Modulation of angiotensin-converting enzyme by nitric oxide[J]. Br J Pharmacol. 1998;124(2):291–98.doi:10.1038/sj.bjp.0701836.
  • Persson K, P A W, Nyhlen K, et al. Nitric oxide donors and angiotensin-converting enzyme inhibitors act in concert to inhibit human angiotensin-converting enzyme activity and platelet aggregation in vitro[J]. Eur J Pharmacol. 2000;406(1):15–23.doi:10.1016/S0014-2999(00)00647-6.
  • Marcelino-Rodriguez I, Almeida Gonzalez D, J J A-S, et al. Inverse association of resistin with physical activity in the general population[J]. PLoS One. 2017;12(8):e0182493.doi:10.1371/journal.pone.0182493.
  • D A Z, Biernat W, Barc J. Roles of leptin and resistin in metabolism, reproduction, and leptin resistance[J]. Domest Anim Endocrinol.2020;73:106472.doi:10.1016/j.domaniend.2020.106472.

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.