References
- Levy D, Garrison RJ, Savage DD, Kannel WB, Castelli WP. Prognostic implications of echocardiographically determined left ventricular mass in the Framingham Heart Study. N Engl J Med. 1990;322(22):1561–66.doi:https://doi.org/10.1056/NEJM199005313222203.
- Artham SM, Lavie CJ, Milani RV, Patel DA, Verma A, Ventura HO. Clinical impact of left ventricular hypertrophy and implications for regression. Prog Cardiovasc Dis. 2009;52(2):153–67.doi:https://doi.org/10.1016/j.pcad.2009.05.002.
- Wang W, Schultz HD, Ma R. Cardiac sympathetic afferent sensitivity is enhanced in heart failure. Am J Physiol. 1999;277(2 Pt 2):H812–817.doi:https://doi.org/10.1152/ajpheart.1999.277.2.H812.
- Wang HJ, Wang W, Cornish KG, Rozanski GJ, Zucker IH. Cardiac sympathetic afferent denervation attenuates cardiac remodeling and improves cardiovascular dysfunction in rats with heart failure. Hypertension. 2014;64(4):745–55.doi:https://doi.org/10.1161/HYPERTENSIONAHA.114.03699.
- Shi Z, Jiang SJ, Wang GH, Xu AL, Guo L. Pro-inflammatory cytokines in paraventricular nucleus mediate the cardiac sympathetic afferent reflex in hypertension. Auton Neurosci. 2014;186:54–61.doi:https://doi.org/10.1016/j.autneu.2014.10.001.
- Zhu GQ, Xu Y, Zhou LM, Li YH, Fan LM, Wang W, Gao XY, Chen Q. Enhanced cardiac sympathetic afferent reflex involved in sympathetic overactivity in renovascular hypertensive rats. Exp Physiol. 2009;94(7):785–94.doi:https://doi.org/10.1113/expphysiol.2008.046565.
- Chen WW, Xiong XQ, Chen Q, Li YH, Kang YM, Zhu GQ. Cardiac sympathetic afferent reflex and its implications for sympathetic activation in chronic heart failure and hypertension. Acta Physiol (Oxf). 2015;213(4):778–94.doi:https://doi.org/10.1111/apha.12447.
- Zahner MR, Li DP, Chen SR, Pan HL. Cardiac vanilloid receptor 1-expressing afferent nerves and their role in the cardiogenic sympathetic reflex in rats. J Physiol. 2003;551(Pt 2):515–23.doi:https://doi.org/10.1113/jphysiol.2003.048207.
- Dampney RA. Functional organization of central pathways regulating the cardiovascular system. Physiol Rev. 1994;74(2):323–64.doi:https://doi.org/10.1152/physrev.1994.74.2.323.
- Cervero F. Sensory innervation of the viscera: peripheral basis of visceral pain. Physiol Rev. 1994;74(1):95–138.doi:https://doi.org/10.1152/physrev.1994.74.1.95.
- Kuo DC, Oravitz JJ, DeGroat WC. Tracing of afferent and efferent pathways in the left inferior cardiac nerve of the cat using retrograde and transganglionic transport of horseradish peroxidase. Brain Res. 1984;321(1):111–18.doi:https://doi.org/10.1016/0006-8993(84)90686-3.
- Conner JM, Lauterborn JC, Yan Q, Gall CM, Varon S. Distribution of brain-derived neurotrophic factor (BDNF) protein and mRNA in the normal adult rat CNS: evidence for anterograde axonal transport. J Neurosci. 1997;17(7):2295–313.doi:https://doi.org/10.1523/JNEUROSCI.17-07-02295.1997.
- Balkowiec A, Kunze DL, Katz DM. Brain-derived neurotrophic factor acutely inhibits AMPA-mediated currents in developing sensory relay neurons. J Neurosci. 2000;20(5):1904–11.doi:https://doi.org/10.1523/JNEUROSCI.20-05-01904.2000.
- Clark CG, Hasser EM, Kunze DL, Katz DM, Kline DD. Endogenous brain-derived neurotrophic factor in the nucleus tractus solitarius tonically regulates synaptic and autonomic function. J Neurosci. 2011;31(34):12318–29.doi:https://doi.org/10.1523/JNEUROSCI.0746-11.2011.
- Ito K, Hirooka Y, Sunagawa K. Blockade of mineralocorticoid receptors improves salt-induced left-ventricular systolic dysfunction through attenuation of enhanced sympathetic drive in mice with pressure overload. J Hypertens. 2010;28(7):1449–58.doi:https://doi.org/10.1097/HJH.0b013e328338bb37.
- Ito K, Hirooka Y, Nakano M, Honda N, Matsukawa R, Sunagawa K. Role of hypothalamic angiotensin type 1 receptors in pressure overload-induced mineralocorticoid receptor activation and salt-induced sympathoexcitation. Hypertens Res. 2013;36(6):513–19.doi:https://doi.org/10.1038/hr.2012.221.
- Franklin Kbjpaxinos G. The mouse brain in stereotaxic coordinates. San Diego: Academic Press; 1997.
- Ito K, Hirooka Y, Sunagawa K. Cardiac sympathetic afferent stimulation induces salt-sensitive sympathoexcitation through hypothalamic epithelial Na+ channel activation. Am J Physiol Heart Circ Physiol. 2015;308(5):H530–539.doi:https://doi.org/10.1152/ajpheart.00586.2014.
- Hong J, Lisco AM, Rudebush TL, Yu L, Gao L, Kitzerow O, Zucker IH, Wang HJ. Identification of cardiac expression pattern of Transient Receptor Potential Vanilloid Type 1 (TRPV1) receptor using a transgenic reporter mouse model. Neurosci Lett. 2020;737:135320.doi:https://doi.org/10.1016/j.neulet.2020.135320.
- Andrei SR, Sinharoy P, Bratz IN, Damron DS. TRPA1 is functionally co-expressed with TRPV1 in cardiac muscle: co-localization at z-discs, costameres and intercalated discs. Channels (Austin). 2016;10(5):395–409.doi:https://doi.org/10.1080/19336950.2016.1185579.
- Hurt CM, Lu Y, Stary CM, Piplani H, Small BA, Urban TJ, Qvit N, Gross GJ, Mochly-Rosen D, Gross ER. Transient receptor potential vanilloid 1 regulates mitochondrial membrane potential and myocardial reperfusion injury. J Am Heart Assoc. 2016;5(9). doi:https://doi.org/10.1161/JAHA.116.003774.
- Yoshie K, Rajendran PS, Massoud L, Mistry J, Swid MA, Wu X, Sallam T, Zhang R, Goldhaber JI, Salavatian S, et al. Cardiac TRPV1 afferent signaling promotes arrhythmogenic ventricular remodeling after myocardial infarction. JCI Insight. 2020;5(3). doi:https://doi.org/10.1172/jci.insight.124477.
- Wang D, Wu Y, Chen Y, Wang A, Lv K, Kong X, He Y, Hu N. Focal selective chemo-ablation of spinal cardiac afferent nerve by resiniferatoxin protects the heart from pressure overload-induced hypertrophy. Biomed Pharmacother. 2019;109:377–85.doi:https://doi.org/10.1016/j.biopha.2018.10.156.
- Hudson LJ, Bevan S, Wotherspoon G, Gentry C, Fox A, Winter J. VR1 protein expression increases in undamaged DRG neurons after partial nerve injury. Eur J Neurosci. 2001;13(11):2105–14.doi:https://doi.org/10.1046/j.0953-816x.2001.01591.x.
- Tran EL, Crawford LK. Revisiting PNS plasticity: how uninjured sensory afferents promote neuropathic pain. Front Cell Neurosci. 2020;14:612982.doi:https://doi.org/10.3389/fncel.2020.612982.
- Kamata Y, Kambe T, Chiba T, Yamamoto K, Kawakami K, Abe K, Taguchi K. Paclitaxel induces upregulation of transient receptor potential vanilloid 1 expression in the rat spinal cord. Int J Mol Sci. 2020;21(12):4341.doi:https://doi.org/10.3390/ijms21124341.
- Patel MB, Stewart JM, Loud AV, Anversa P, Wang J, Fiegel L, Hintze TH. Altered function and structure of the heart in dogs with chronic elevation in plasma norepinephrine. Circulation. 1991;84(5):2091–100.doi:https://doi.org/10.1161/01.CIR.84.5.2091.
- Schlaich MP, Kaye DM, Lambert E, Sommerville M, Socratous F, Esler MD. Relation between cardiac sympathetic activity and hypertensive left ventricular hypertrophy. Circulation. 2003;108(5):560–65.doi:https://doi.org/10.1161/01.CIR.0000081775.72651.B6.
- Akers WS, Cross A, Speth R, Dwoskin LP, Cassis LA. Renin-angiotensin system and sympathetic nervous system in cardiac pressure-overload hypertrophy. Am J Physiol Heart Circ Physiol. 2000;279(6):H2797–2806.doi:https://doi.org/10.1152/ajpheart.2000.279.6.H2797.
- Thilo F, Liu Y, Schulz N, Gergs U, Neumann J, Loddenkemper C, Gollasch M, Tepel M. Increased transient receptor potential vanilloid type 1 (TRPV1) channel expression in hypertrophic heart. Biochem Biophys Res Commun. 2010;401(1):98–103.doi:https://doi.org/10.1016/j.bbrc.2010.09.017.
- Zhong B, Rubinstein J, Ma S, Wang DH. Genetic ablation of TRPV1 exacerbates pressure overload-induced cardiac hypertrophy. Biomed Pharmacother. 2018;99:261–70.
- Gao L, Zhu Z, Zucker IH, Wang W. Cardiac sympathetic afferent stimulation impairs baroreflex control of renal sympathetic nerve activity in rats. Am J Physiol Heart Circ Physiol. 2004;286(5):H1706–1711.doi:https://doi.org/10.1152/ajpheart.01097.2003.
- Wang WZ, Gao L, Pan YX, Zucker IH, Wang W. Differential effects of cardiac sympathetic afferent stimulation on neurons in the nucleus tractus solitarius. Neurosci Lett. 2006;409(2):146–50.doi:https://doi.org/10.1016/j.neulet.2006.09.032.
- Mancia G, Grassi G, Giannattasio C, Seravalle G. Sympathetic activation in the pathogenesis of hypertension and progression of organ damage. Hypertension. 1999;34(4):724–28.doi:https://doi.org/10.1161/01.HYP.34.4.724.
- Grassi G, Giannattasio C, Cléroux J, Cuspidi C, Sampieri L, Bolla GB, Mancia G. Cardiopulmonary reflex before and after regression of left ventricular hypertrophy in essential hypertension. Hypertension. 1988;12(3):227–37.doi:https://doi.org/10.1161/01.HYP.12.3.227.
- Head GA, Minami N. Importance of cardiac, but not vascular, hypertrophy in the cardiac baroreflex deficit in spontaneously hypertensive and stroke-prone rats. Am J Med. 1992;92(4b):54s–59s.doi:https://doi.org/10.1016/0002-9343(92)90148-5.
- Yan Q, Tang J, Zhang X, Wu L, Xu Y, Wang L. Does transient receptor potential vanilloid type 1 alleviate or aggravate pathological myocardial hypertrophy? Front Pharmacol. 2021;12:681286.doi:https://doi.org/10.3389/fphar.2021.681286.
- Wang Q, Ma S, Li D, Zhang Y, Tang B, Qiu C, Yang Y, Yang D. Dietary capsaicin ameliorates pressure overload-induced cardiac hypertrophy and fibrosis through the transient receptor potential vanilloid type 1. Am J Hypertens. 2014;27(12):1521–29.doi:https://doi.org/10.1093/ajh/hpu068.
- Buckley CL, Stokes AJ. Mice lacking functional TRPV1 are protected from pressure overload cardiac hypertrophy. Channels (Austin). 2011;5(4):367–74.doi:https://doi.org/10.4161/chan.5.4.17083.
- Melleby AO, Romaine A, Aronsen JM, Veras I, Zhang L, Sjaastad I, Lunde IG, Christensen G. A novel method for high precision aortic constriction that allows for generation of specific cardiac phenotypes in mice. Cardiovasc Res. 2018;114(12):1680–90.doi:https://doi.org/10.1093/cvr/cvy141.
- Bosch L, de Haan JJ, Bastemeijer M, van der Burg J, van der Worp E, Wesseling M, Viola M, Odille C, El Azzouzi H, Pasterkamp G, et al. The transverse aortic constriction heart failure animal model: a systematic review and meta-analysis. Heart Fail Rev. 2021;26(6):1515–1524.
- Patel A, Patel D. Congestive heart failure model representing aortic banding induced hypertrophy: a study to analyse extent of pressure overload and alteration in myocardial structure and function. IJC Heart & Vasculature. 2021;34:100755.doi:https://doi.org/10.1016/j.ijcha.2021.100755.
- Richards DA, Aronovitz MJ, Calamaras TD, Tam K, Martin GL, Liu P, Bowditch HK, Zhang P, Huggins GS, Blanton RM. Distinct phenotypes induced by three degrees of transverse aortic constriction in mice. Sci Rep. 2019;9(1):5844.doi:https://doi.org/10.1038/s41598-019-42209-7.
- Randhawa PK, Jaggi AS. TRPV1 channels in cardiovascular system: a double edged sword? Int J Cardiol. 2017;228:103–13.doi:https://doi.org/10.1016/j.ijcard.2016.11.205.
- Randhawa PK, Jaggi AS. A review on potential involvement of TRPV(1) channels in ischemia-reperfusion injury. J Cardiovasc Pharmacol Ther. 2018;23(1):38–45.doi:https://doi.org/10.1177/1074248417707050.
- Christie S, Wittert GA, Li H, Page AJ. Involvement of TRPV1 Channels in Energy Homeostasis. Front Endocrinol (Lausanne). 2018;9(420). doi:https://doi.org/10.3389/fendo.2018.00420.
- Shuba YM. Beyond neuronal heat sensing: diversity of TRPV1 heat-capsaicin receptor-channel functions. Front Cell Neurosci. 2020;14:612480.doi:https://doi.org/10.3389/fncel.2020.612480.
- Li L, Wang F, Wei X, Liang Y, Cui Y, Gao F, Zhong J, Pu Y, Zhao Y, Yan Z, et al. Transient receptor potential vanilloid 1 activation by dietary capsaicin promotes urinary sodium excretion by inhibiting epithelial sodium channel α subunit-mediated sodium reabsorption. Hypertension. 2014;64(2):397–404. doi:https://doi.org/10.1161/HYPERTENSIONAHA.114.03105.
- Marshall NJ, Liang L, Bodkin J, Dessapt-Baradez C, Nandi M, Collot-Teixeira S, Smillie SJ, Lalgi K, Fernandes ES, Gnudi L, et al. A role for TRPV1 in influencing the onset of cardiovascular disease in obesity. Hypertension. 2013;61:246–52.
- Wang Y, Babánková D, Huang J, Swain GM, Wang DH. Deletion of transient receptor potential vanilloid type 1 receptors exaggerates renal damage in deoxycorticosterone acetate-salt hypertension. Hypertension. 2008;52(2):264–70.doi:https://doi.org/10.1161/HYPERTENSIONAHA.108.110197.
- Zhong B, Ma S, Wang DH. Ablation of TRPV1 elevates nocturnal blood pressure in western diet-fed mice. Curr Hypertens Rev. 2019;15(2):144–53.doi:https://doi.org/10.2174/1573402114666181031141840.
- Hori Y, Temma T, Wooten C, Sobowale C, Chan C, Swid M, Ajijola OA. Cardiac afferent signaling partially underlies premature ventricular contraction-induced cardiomyopathy. Heart Rhythm. 2021;18(9):1586–95.doi:https://doi.org/10.1016/j.hrthm.2021.04.004.