Diagnostic signature and immune characteristic of aging-related genes from placentas in Preeclampsia

References

• Chappell LC, Cluver CA, Kingdom J, Tong S. 2021. Pre-eclampsia. Lancet. 398(10297):341–54. doi:10.1016/S0140-6736(20
   PubMed Web of Science ®Google Scholar
• Poon LC, Shennan A, Hyett JA, Kapur A, Hadar E, Divakar H, Hod M, Silva Costa F, Dadelszen P, McIntyre HD. 2019. The International Federation of Gynecology and Obstetrics (FIGO) initiative on pre-eclampsia: a pragmatic guide for first-trimester screening and prevention. Int J Gynaecol Obstet. 145(Suppl 1):1–33. doi:10.1002/ijgo.12802
   PubMed Web of Science ®Google Scholar
• Li H, Nawsherwan F, Yin C, Haq S, Mubarik IU, Hua L, Nabi G, Khan S, Hua L. 2022. Changes in adverse pregnancy outcomes in women with advanced maternal age (AMA) after the enactment of China’s universal two-child policy. Sci Rep. 12(1):5048. doi:10.1038/s41598-022-08396-6
   PubMed Web of Science ®Google Scholar
• Dongarwar D, Tahseen D, Aliyu MH, Salihu HM. 2021. Pregnancy outcomes among Asian Americans of advanced maternal age, 1992-2018. J Obstet Gynaecol Res. 47(6):2117–25. doi:10.1111/jog.14790
   PubMed Web of Science ®Google Scholar
• Nogueira da Gama SG, Martinelli KG, Soares Dias BA, Pereira-Esteves AP, Do Carmo Leal M, Dos Santos-Neto ET. A population-based study of the relationship between advanced maternal age and premature/early-term birth in Brazil. Int J Gynaecol Obstet. 2021. doi:10.1002/ijgo.14057.
   PubMed Web of Science ®Google Scholar
• Londero AP, Orsaria M, Marzinotto S, Grassi T, Fruscalzo A, Calcagno A, … Mariuzzi L. 2016. Placental aging and oxidation damage in a tissue micro-array model: an immunohistochemistry study. Histochem Cell Biol. 146(2):191–204. doi:10.1007/s00418-016-1435-6
   PubMed Web of Science ®Google Scholar
• Mayne BT, Leemaqz SY, Smith AK, Breen J, Roberts CT, Bianco-Miotto T. 2017. Accelerated placental aging in early onset preeclampsia pregnancies identified by DNA methylation. Epigenomics. 9(3):279–89. doi:10.2217/epi-2016-0103
   PubMed Web of Science ®Google Scholar
• Wickham H. ggplot2: elegant graphics for data analysis. Springer-Verlag: New York, NY. 2016. https://doi.org/10.1007/978-0-387-98141-3.
   Google Scholar
• Miller EC, Wilczek A, Bello NA, Tom S, Wapner R, Suh Y. Pregnancy, preeclampsia and maternal aging: from epidemiology to functional genomics. Ageing Res Rev. 2022;73:101535. doi:10.1016/j.arr.2021.101535.
   PubMed Web of Science ®Google Scholar
• Manna S, McCarthy C, McCarthy FP. Placental ageing in adverse pregnancy outcomes: telomere shortening, cell senescence, and mitochondrial dysfunction. Oxid Med Cell Longev. 2019;(2019:3095383. doi:10.1155/2019/3095383.
   PubMed Web of Science ®Google Scholar
• Hernandez-Segura A, Nehme J, Demaria M. 2018. Hallmarks of cellular senescence. Trends Cell Biol. 28(6):436–53. doi:10.1016/j.tcb.2018.02.001
   PubMed Web of Science ®Google Scholar
• Shibuya M. 2011. Involvement of Flt-1 (VEGF receptor-1) in cancer and preeclampsia. Proc Jpn Acad Ser B Phys Biol Sci. 87(4):167–78. doi:10.2183/pjab.87.167
   PubMed Web of Science ®Google Scholar
• Zeisler H, Llurba E, Chantraine F, Vatish M, Staff AC, Sennstrom M, Verlohren S, Brennecke SP, Stepan H, Allegranza D. 2016. Predictive value of the sFlt-1: Plgfratio in women with suspected preeclampsia. N Engl J Med. 374(1):13–22. doi:10.1056/NEJMoa1414838
   PubMed Web of Science ®Google Scholar
• Robertson SA. 2019. Preventing preeclampsia by silencing soluble Flt-1? N Engl J Med. 380(11):1080–82. doi:10.1056/NEJMcibr1817501
   PubMed Web of Science ®Google Scholar
• Park HY, Kwon HM, Lim HJ, Hong BK, Lee JY, Park BE, … Kim HS. 2001. Potential role of leptin in angiogenesis: leptin induces endothelial cell proliferation and expression of matrix metalloproteinases in vivo and in vitro. Exp Mol Med. 33(2):95–102. doi:10.1038/emm.2001.17
   PubMed Web of Science ®Google Scholar
• Vuolteenaho K, Koskinen A, Kukkonen M, Nieminen R, Paivarinta U, Moilanen T, Moilanen E. 2009. Leptin enhances synthesis of proinflammatory mediators in human osteoarthritic cartilage–mediator role of NO in leptin-induced PGE2, IL-6, and IL-8 production. Mediators Inflamm. 2009:345838. doi:10.1155/2009/345838.
   PubMed Web of Science ®Google Scholar
• Hogg K, Blair JD, von Dadelszen P, Robinson WP. 2013. Hypomethylation of the LEP gene in placenta and elevated maternal leptin concentration in early onset pre-eclampsia. Mol Cell Endocrinol. 367(1–2):64–73. doi:10.1016/j.mce.2012.12.018
   PubMed Web of Science ®Google Scholar
• Xiang Y, Cheng Y, Li X, Li Q, Xu J, Zhang J, Zhao X, Xing Q, Wang L, He L. 2013. Up-regulated expression and aberrant DNA methylation of LEP and SH3PXD2A in pre-eclampsia. PLoS One. 8(3):e59753. doi:10.1371/journal.pone.0059753
   PubMed Web of Science ®Google Scholar
• Szabo S, Mody M, Romero R, Xu Y, Karaszi K, Mihalik N, … Than NG. 2015. Activation of villous trophoblastic p38 and ERK1/2 signaling pathways in preterm preeclampsia and HELLP syndrome. Pathol Oncol Res. 21(3):659–68. doi:10.1007/s12253-014-9872-9
   PubMed Web of Science ®Google Scholar
• Roland L, Beauchemin D, Acteau G, Fradette C, St-Pierre I, Bilodeau JF. 2010. Effects of labor on placental expression of superoxide dismutases in preeclampsia. Placenta. 31(5):392–400. doi:10.1016/j.placenta.2010.02.007
   PubMed Web of Science ®Google Scholar
• Wang Y, Walsh SW. Antioxidant activities and mRNA expression of superoxide dismutase, catalase, and glutathione peroxidase in normal and preeclamptic placentas. J Soc Gynecol Investig. 1996;3(4):179–84. doi:10.1177/107155769600300404.
   PubMedGoogle Scholar
• Wang Z, Cai B, Cao C, Lv H, Dai Y, Zheng M, Hu Y, Peng Y, Gou W, Wang J. Downregulation of CD151 induces oxidative stress and apoptosis in trophoblast cells via inhibiting ERK/Nrf2 signaling pathway in preeclampsia. Free Radic Biol Med. 2021;164:249–57. doi:10.1016/j.freeradbiomed.2020.12.441.
   PubMed Web of Science ®Google Scholar
• Qu J, Zheng B, Ohuchida K, Feng H, Chong SJF, Zhang X, … Nakamura M. PIK3CB is involved in metastasis through the regulation of cell adhesion to collagen I in pancreatic cancer. J Adv Res. 2021;33:127–40. doi:10.1016/j.jare.2021.02.002.
   PubMed Web of Science ®Google Scholar
• Whale AD, Colman L, Lensun L, Rogers HL, Shuttleworth SJ. Functional characterization of a novel somatic oncogenic mutation of PIK3CB. Signal Transduct Target Ther. 2017;2:17063. doi:10.1038/sigtrans.2017.63.
   PubMed Web of Science ®Google Scholar
• Pridham KJ, Le L, Guo S, Varghese RT, Algino S, Liang Y, … Sheng Z. 2018. PIK3CB/p110beta is a selective survival factor for glioblastoma. Neuro Oncol. 20(4):494–505. doi:10.1093/neuonc/nox181
   PubMed Web of Science ®Google Scholar
• Wang Y, Chen A, Zheng C, Zhao L. 2021. miR-92a promotes cervical cancer cell proliferation, invasion, and migration by directly targeting PIK3R1. J Clin Lab Anal. 35(8):e23893. doi:10.1002/jcla.23893
   PubMed Web of Science ®Google Scholar
• Lee KY, Ahn YM, Kim SH, Kang HG, Joo EJ. 2018. Genetic association study of CSNK1E gene in bipolar disorder and circadian characteristics. Nord J Psychiatry. 72(8):599–604. doi:10.1080/08039488.2018.1509125
   PubMed Web of Science ®Google Scholar
• Chen X, Jin J, Wang Q, Xue H, Zhang N, Du Y, Liu Z, Zhang B, Wu J, Liu Z. 2019. A de novo pathogenic CSNK1E mutation identified by exome sequencing in family trios with epileptic encephalopathy. Hum Mutat. 40(3):281–87. doi:10.1002/humu.23690
   PubMed Web of Science ®Google Scholar
• Collier AY, Smith LA, Karumanchi SA. 2021. Review of the immune mechanisms of preeclampsia and the potential of immune modulating therapy. Hum Immunol. 82(5):362–70. doi:10.1016/j.humimm.2021.01.004
   PubMed Web of Science ®Google Scholar
• Kalman L, Lindegren ML, Kobrynski L, Vogt R, Hannon H, Howard JT, Buckley R. 2004. Mutations in genes required for T-cell development: IL7R, CD45, IL2RG, JAK3, RAG1, RAG2, ARTEMIS, and ADA and severe combined immunodeficiency: huGE review. Genet Med. 6(1):16–26. doi:10.1097/01.GIM.0000105752.80592.A3
   PubMed Web of Science ®Google Scholar
• Zhao S, Lv N, Li Y, Liu T, Sun Y, Chu X. 2020. Identification and characterization of methylation-mediated transcriptional dysregulation dictate methylation roles in preeclampsia. Hum Genomics. 14(1):5. doi:10.1186/s40246-020-0256-9
   PubMed Web of Science ®Google Scholar
• Franklin AD, Saqibuddin J, Stephens K, Birkett R, Marsden L, Ernst LM, Mestan KK. Cord blood alpha klotho is decreased in small for gestational age preterm infants with placental lesions of accelerated aging. Placenta. 2019;87:1–7. doi:10.1016/j.placenta.2019.08.088.
   PubMed Web of Science ®Google Scholar