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Original Article

Effect of age on the profile of alkanes in normal human breath

, &
Pages 57-63 | Received 26 Nov 1999, Published online: 07 Jul 2009

References

  • Fridovich I. The biology of oxygen radicals. Science 1978; 201: 875–880
  • Kneepkens C.M.F., Ferreira C., Lepage G., Roy C.C. The hydrocarbon breath test in the study of lipid peroxidation: Principles and practice. Clinical Investigation Medicine 1992; 15: 163–186
  • Kneepkens C.M.F., Lepage G., Roy C.C. The potential of the hydrocarbon breath test as a measure of lipid peroxidation. Free Radical Biology and Medicine 1994; 17: 127–160
  • Pryor W.A. Measurement of oxidative stress status in humans. Cancer Epidemiology Biomarkers and Prevention 1993; 2: 289–292
  • Cortopassi G.A., Wong A. Mitochondria in organismal aging and degeneration. Biochimica et Biophysica Acta 1999; 1410: 183–193
  • Von Zglinicki T. Telomeres: Influencing the rate of aging. Annals of the New York Academy of Sciences 1998; 854: 318–327
  • Halliwell B., Gutteridge J.M.C., Cross C.E. Free radicals, antioxidants, and human disease: Where are we now?. Journal of Laboratory and Clinical Medicine 1992; 119: 598–620
  • Hietanen E., Bartsch H., Bereziat J.-C., Camus A.-M., McClinton S., Eremin O., Davidson L., Boyle P. Diet and oxidative stress in breast, colon and prostate cancer patients: A case control study. European Journal of Clinical Nutrition 1994; 48: 575–586
  • Sobotka P.A., Gupta D.K., Lansky D.M., Costanzo M.R., Zarling E.J. Breath pentane is a marker of acute cardiac allograft rejection. Journal of Heart Lung Transplantation 1994; 13: 224–229
  • Weitz Z.W., Birnbaum A.J., Sobotka P.A., Zarling E.J., Skosey J.L. High breath pentane concentrations during acute myocardial infarction. Lancet 1991; 337: 933–935
  • Kovaleva E.S., Orlov O.N., Tsutsul'kovskaia Mia, Vladimirova T.V., Beliaev B.S. Lipid peroxidation processes in patients with schizophrenia. Zh Nevropatol Psikiatr 1989; 89: 108–110
  • Humad S., Zarling E., Clapper M., Skosey J.L. Breath pentane excretion as a marker of disease activity in rheumatoid arthritis. Free Radical Research Communications 1988; 5: 101–106
  • Olopade C.O., Zakkar M., Swedler W.I., Rubinstein I. Exhaled pentane levels in acute asthma. Chest 1997; 111: 862–865
  • Phillips M., Gleeson K., Hughes J.M.B., Greenberg J., Cataneo R.N., Baker L., McVay W.P. Volatile organic compounds in breath as markers of lung cancer: A cross-sectional study. Lancet 1999; 353: 1930–1933
  • Cailleux A., Allain P. Is pentane a normal constituent of human breath?. Free Radical Research Communications 1993; 18: 323–327
  • Phillips M., Greenberg J., Awad J. Metabolic and environmental origins of volatile organic compounds in breath. Journal of Clinical Pathology 1994; 47: 1052–1053
  • Phillips M., Sabas M., Greenberg J. Alveolar gradient of pentane in normal human breath. Free Radical Research Communications 1994; 20: 333–337
  • Phillips M., Herrera J., Krishnan S., Zain M., Greenberg J., Cataneo R.N. Variation in volatile organic compounds in the breath of normal humans. Journal of Chromatography B 1999; 629: 75–88
  • Phillips M. Method for the collection and assay of volatile organic compounds in breath. Analytical Biochemistry 1997; 247: 272–278
  • Zarling E.J., Mobarhan S., Bowen P., Kamath S. Pulmonary pentane excretion increases with age in healthy subjects. Mechanisms of Ageing and Development 1993; 67: 141–147
  • Jones M., Shiel N., Summan M., Sharer N.M., Hambleton G., Super M., Braganza J.M. Application of breath pentane analysis to monitor age-related change in free radical activity. Biochemical Society Transactions 1993; 21: 485S–485S
  • Sagai M., Ichinose T. Age-related changes in lipid peroxidation as measured by ethane, ethylene, butane and pentane in respired gases of rats. Life Sciences 1980; 27: 731–738
  • Crosbie S.J., Blaine P.G., Williams F.M. Metabolism of n-hexane by rat liver and extrahepatic tissues and the effect of cytochrome P-450 inducers. Human and Experimental Toxicology 1997; 16: 131–137
  • Scheller U., Zimmer T., Kargel E., Schunck W.H. Characterization of the n-alkane and fatty acid hydroxylating cytochrome P-450 forms 52A3 and 52A4. Archives of Biochemistry and Biophysics 1996; 328: 245–254
  • George J., Byth K., Farrell G.C. Age but not gender selectively affects expression of individual cytochrome p450 proteins in human liver. Biochemical Pharmacology 1995; 50: 727–730
  • Sotaniemi E.A., Arranto A.J., Pelkonen O., Pasanen M. Age and cytochrome p450-linked drug metabolism in humans: An analysis of 226 subjects with equal histopathologic conditions. Clinical Pharmacology and Therapeutics 1997; 61: 331–339
  • Tanaka E. In vivo age-related changes in hepatic drug-oxidizing capacity in humans. Journal of Clinical Pharmacology and Therapeutics 1998; 23: 247–255
  • Charpentier K.P., von Moltke L.L., Poku J.W., Harmatz J.S., Shader R.I., Greenblatt D.J. Alprazolam hydroxylation by mouse liver microsomes in vitro: The effect of age and phenobarbital induction. Biopharmacy and Drug Disposition 1997; 18: 139–149
  • Williams D., Woodhouse K. The relationship between age and cutaneous aryl hydrocarbon hydroxylase (AHH) activity. Age and Ageing 1995; 24: 213–216
  • James J.T., Limero T.F., Leano H.J., Boyd J.F., Covington P.A. Volatile organic contaminants found in the habitable environment of the space shuttle: STS-26 to STS-55. Aviation, Space and Environmental Medicine 1994; 65: 851–857
  • Troger U., Meyer F.P. Influence of endogenous and exogenous effectors on the pharmacokinetics of theophylline. Focus on biotransformation. Clinical Pharmacokinetics 1995; 28: 287–314
  • Kohlmuller D., Kochen W. Is n-pentane really an index of lipid peroxidation in humans and animals? A methodological reevaluation. Analytical Biochemistry 1993; 210: 266–276

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