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Original Article

Quercetin prevents glutathione depletion induced by dehydroascorbic acid in rabbit red blood cells

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Pages 639-648 | Received 03 Jul 2000, Published online: 07 Jul 2009

References

  • Rice-Evans C.A., Miller N.J., Paganga G. Antioxidant properties of phenolic compounds. Trends in Plant Science 1997; 2: 152–159
  • Bors W., Heller W., Michel C., Saran M. Flavonoids as antioxidants: determination of radical scavenging efficiencies. Methods in Enzymology 1990; 186: 343–355
  • Bors W., Michel C., Saran M. Flavonoids as antioxidants: rate constants for reactions with oxygen radicals. Methods in Enzymology 1994; 234: 420–429
  • Jovanovic S.V., Steenken S., Tosic M., Marjanovic B., Simic M.G. Flavonoids as antioxidants. Journal of American Chemical Society 1994; 116: 4846–4851
  • Afanas'ev I.B., Dorozhko A.I., Brodskii A.W., Korstyuk V.A., Potapovitch A.I. Chelating and free radical scavenging mechanisms of inhibitory action of rutin and quercetin in lipid peroxidation. Biochemical Pharmacology 1989; 38: 1763–1768
  • Terao J., Piskula M., Yao Q. Protective effect of epicatechin, epicatechin gallate, and quercetin on lipid peroxidation in phospholipid bilayers. Archives of Biochemistry and Biophysics 1994; 308: 278–284
  • Ueda T., Armstrong D. Preventive effect of natural and synthetic antioxidants on lipid peroxidation in mammalian eye. Ophthalmic Research 1996; 28: 184–192
  • Sestili P., Guidarelli A., Dachà M., Cantoni O. Quercetin prevents DNA single strand breakage and cytotoxicity caused by tert-butylhydroperoxide: free radical scavenging versus iron chelating mechanism. Free Radical Biology & Medicine 1998; 25: 196–200
  • Ferrali M., Signorini C., Caciotti B., Sugherini L., Ciccoli L., Giachetti D., Comporti M. Protection against oxidative damage of erythrocyte membrane by the flavonoid quercetin and its relation to iron chelating activity. FEBS Letters 1997; 416: 123–129
  • Skaper S.D., Fabris M., Ferrari V., Carbonare M. Dalle, Leon A. Quercetin protects cutaneous tissue-associated cell types including sensory neurons from oxidative stress induced by glutathione depletion: cooperative effects of ascorbic acid. Free Radical Biology & Medicine 1997; 22: 669–678
  • Rose R.C. Transport of ascorbic acid and other water-soluble vitamins. Biochimica et Biophysica Acta 1988; 947: 335–366
  • Vera J.C., Rivas C.I., Fischbarg J., Golde D.W. Mammalian facilitative hexose transporters mediate the transport of dehydroascorbic acid. Nature 1993; 364: 79–82
  • May J.M. Is ascorbic acid an antioxidant for the plasma membrane?. FASEB Journal 1999; 13: 995–1006
  • Mendiratta S., Zhi-Chao Q., May J.M. Enzyme-dependent ascorbate recycling in human erythrocytes: role of thioredoxin reductase. Free Radical Biology & Medicine 1998; 25: 221–228
  • May J.M., Zhi-Chao Q., Whitesell R.R. Ascorbic acid recycling enhances the antioxiodant reserve of human erythrocytes. Biochemistry 1995; 34: 12721–12728
  • Iheanacho E.N., Stocker R., Hunt N.H. Redox metabolism of vitamin C in blood of normal and malaria-infacted mice. Biochimica et Biophysica Acta 1993; 1182: 15–21
  • Waskho P.W., Wang Y., Levine M. Ascorbic acid recycling in human neutrophils. Journal of Biological Chemistry 1993; 268: 15531–15535
  • Beutler E. Red cell metabolism: a manual of Biochemical Methods. Grune & Stratton, New York 1984, In
  • Wells W.W., Xu D.P., Yang Y., Rocque P.A. Mammalian thioltransferase (glutaredoxin) and protein disulfide isomerase have dehydroascorbate reductase activity. Journal of Biological Chemistry 1990; 265: 15361–15364
  • Avron M., Shavit N. A sensitive and simple method for determination of ferrocyanide. Analytical Biochemistry 1963; 6: 549–555
  • Menghinello P., Cucchiarini L., Palma F., Agostini D., Dachà M., Stocchi V. Simultaneous analysis of flavonoid aglycones in natural products using an RP-HPLC method. Journal of Liquid Chromatography & Related Technologies 1999; 22: 3007–3018
  • Fiorani M., Saltarelli R., De Sanctis R., Palma F., Ceccaroli P., Stocchi V. Role of dehydroascorbate in rabbit erythrocyte hexokinase inactivation induced by ascorbic acid/FeII. Archives in Biochemistry and Biophysics 1996; 334: 357–361
  • Fiorani M., De Sanctis R., Saltarelli R., Stocchi V. Hexokinase inactivation induced by ascorbic acid/Fe(II) in rabbit erythrocytes is independent of glutathione-reductive processes and appears to be mediated by dehydroascorbic acid. Archives of Biochemistry and Biophysics 1997; 342: 191–196
  • Fiorani M., De Sanctis R., Scarlatti F., Stocchi V. Substrates of hexokinase, glucose-6-phosphate dehydrogenase, and glyceraldehyde-3-phosphate dehydrogenase prevent the inhibitory response induced by ascorbic acid/iron and dehydroascorbic acid in rabbit erythrocytes. Archives of Biochemistry and Biophysics 1998; 356: 159–166
  • Park J.B., Levine M. Intracellular accumulation of ascorbic acid is inhibited by flavonoids via blocking of dehydroascorbic acid and ascorbic acid uptakes in HL-60, U937 and Jurkat cells. Journal of Nutrition 2000; 130: 1297–1302
  • Winkler B.S., Orselli S.M., Rex T.S. The redox couple between glutathione and ascorbic acid: a chemical and physiological perspective. Free Radical Biology & Medicine 1994; 17: 333–349
  • Xu D.P., Washburn M.P., Sun G.P., Wells W.W. Purification and characterisation of a glutathione dependent dehydroascorbate reductase from human erythrocytes. Biochemical and Biophysical Research Communications 1996; 221: 117–121
  • Cha M.K., Kim I.-H. Thioredoxin-linked peroxidase from human red blood cell: evidence for the existence of thioredoxin and thioredoxin reductase in human red blood cell. Biochemical and Biophysical Research Communications 1995; 217: 900–907
  • May J.M., Mendiratta S., Hill K.E., Burk R.F. Reduction of dehydroascorbate to ascorbate by the selenoenzyme thioredoxin reductase. The Journal of Biological Chemistry 1997; 272: 22607–22610
  • Rose R.C., Bode A.M. Biology of free radical scavengers: an evaluation of ascorbate. FASEB Journal 1993; 7: 1135–1142
  • Wells W.W., Xu D.P., Yang Y., Rocque P.A. Mammalian thioltransferase (glutaredoxin) and protein disulfide isomerase have dehydroascorbate reductase activity. Journal of Biological Chemistry 1990; 265: 15361–15364
  • Rice-Evans C., Miller N.J., Paganga G. Structure-antioxidant activity relationships of flavonoids and phenolic acid. Free Radical Biology & Medicine 1996; 20: 933–956
  • Cao G., Sofic E., Prior R. Antioxidant and prooxidant behaviour of flavonoids: structure-activity relationships. Free Radical Biology & Medicine 1997; 22: 749–760
  • Clark M.G., Partick E.J., Patten G.S. Evidence for the extracellular reduction of ferricyanide by rat liver. Biochemical Journal 1981; 200: 565–572
  • Morré D.J., Crane F.L., Eriksson L.C., Löw H., Morré D.M. NADH oxidase of liver plasma membrane stimulated by diferric transferrin and neoplastic transformation induced by the carcinogen 2-acetylaminofluorene. Biochimica et Biophysica Acta 1991; 1057: 140–146
  • Rikans L.E., Moore D.R. Effect of aging on aqueous-phase antioxidants in tissues of male Fischer rats. Biochimica et Biophysica Acta 1988; 966: 269–275
  • Lindsay R.M., Jamleson N.S.D., Walker S.A., McGuigan C.C., Smith W., Baird J.D. Tissue ascorbic acid and polyol pathway metabolism in experimental diabetes. Diabetologia 1998; 41: 516–523
  • Sinclair A.J., Girling A.J., Gray L., Lunec J., Barnet A.H. An investigation of the relationship between free radical activity and vitamin C metabolism in elderly diabetic subjects with retinopathy. Gerontology 1992; 38: 268–274
  • Lunec J., Blake D.R. The determination of dehydroascorbic acid and ascorbic acid in the serum and synovial fluid of patients with reumatoid arthritis (RA). Free Radical Research Communications 1985; 1: 31–39
  • Lohmann W. Ascorbic acid and cataract. Annals New York Academy of Sciences 1987; 498: 307–311
  • Nagaraj R.H., Monnier V.M. Isolation and characterisation of a blue fluorophore from human eye lens crystallins: in vitro formation from Maillard reaction with ascorbate and ribose. Biochimica et Biophysica Acta 1992; 1116: 34–42
  • Slight S.H., Feather M.S., Orthwerth B.J. Glycation of lens proteins by the oxidation products of ascorbic acid. Biochimica et Biophysica Acta 1990; 1038: 367–374

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