Protective effects of antioxidants against smokeless tobacco-induced oxidative stress and modulation of Bcl-2 and p53 genes in human oral kerathnocytes

References

• Johansson S.L., Hirsch J.M., Larsson P.A., Saidi J., Osterdahl B.G. Snuff-induced carcinogenesis: effect of snuff in rats initiated with 4-nitroquinoline-N-oxide. Cancer Research 1989; 49: 3063–3069
   PubMed Web of Science ®Google Scholar
• Bagchi M., Bagchi D., Hassoun E.A., Stohs S.J. Smokeless tobacco induced increases in hepatic lipid perioxidation, DNA damage and excretion of urinary lipid metabolites. International Journal of Experimental Pathology 1994; 7: 197–202
   Google Scholar
• Bagchi M., Bagchi D., Hassoun E.A., Stohs S.J. Subchronic effects of smokeless tobacco extract (STE) on hepatic lipid peroxidation, DNA damage and excretion of urinary lipid metabolites in rats. Toxicology 1998; 127: 29–38
   Google Scholar
• Hassoun E.A., Bagchi D., Bagchi M., Stohs S.J. Effect of vitamin E succinate on smokeless tobacco-induced production of nitric oxide by rat peritoneal macrophages and J774A.1 macrophage cells in culture. Free Radical Biology and Medicine 1995; 18: 577–583
   PubMed Web of Science ®Google Scholar
• Bagchi D., Hassoun E.A., Bagchi M., Stohs S.J. Protective effects of free radical scavengers and antioxidants against smokeless tobacco extract (STE) induced oxidative stress in macrophage J774A.1 cell cultures. Archives of Environmental Contaminants and Toxicology 1995; 29: 424–428
   PubMed Web of Science ®Google Scholar
• Pryor W.A. Cigarette smoke radicals and the role of free radicals in chemical carcinogenicity. Environmental Health Perspectives 1997; 105: 875–882
   PubMed Web of Science ®Google Scholar
• Bagchi M., Kuszynski C.A., Patterson E.B., Tang L., Bagchi D., Saini T., Stohs S.J. In vitro free radical production in human oral keratinocytes induced by smokeless tobacco extract. In vitro Toxicology 1997; 10: 263–274
   Google Scholar
• Bagchi M., Balmoori J., Bagchi D., Ray S.D., Kuszynski C., Stohs S.J. Smokeless tobacco, oxidative stress, apoptosis, and antioxidants in human oral keratinocytes. Free Radical Biology and Medicine 1999; 26: 992–1000
   PubMed Web of Science ®Google Scholar
• Choisy-Rossi C., Reisdorf P., Yonish-Rouach E. Mechanisms of p53-induced apoptosis: In search of genes which are regulated during p53-mediated cell death. Toxicology Letters 1998; 28: 102–103, 491–496
   Google Scholar
• Hockenbery D.M., Oltvai Z.N., Yin X.M., Milliman C.L., Korsmeyer S.J. Bcl-2 functions in an antioxidant pathway to prevent apoptosis. Cell 1993; 75: 241–251
   PubMed Web of Science ®Google Scholar
• Li P.F., Dietz R., von Harsdorf R. p53 regulates mitochondrial membrane potential through reactive oxygen species and induces cytochrome c independent apoptosis blocked by Bcl-2. EMBO Journal 1999; 18: 6027–6036
   PubMed Web of Science ®Google Scholar
• Waikel R.L., Wang X.J., Roop D.R. Targeted expression of c-myc in the epidermis alters normal proliferation, differentiation and UV-B induced apoptosis. Oncogene 1999; 18: 4870–4878
   PubMedGoogle Scholar
• Li S.L., Kim M.S., Cherrick H.M., Park N.H. Low p53 level in immortal non-tumorigenic oral keratinocytes harboring HPV-16 DNA. European Journal of Cancer Biology and Oral Oncology 1992; 28B: 129–134
   Google Scholar
• Kasten M.M., Giordano A. pRb and cdks in apoptosis and the cell cycle. Cell Death Differentiation 1998; 5: 132–140
   PubMed Web of Science ®Google Scholar
• Hollstein M., Sidranski D., Vogelstein B., Harris C.C. p53 mutations in human cancers. Science 1991; 253: 49–53
   PubMed Web of Science ®Google Scholar
• Beham A., Marin M.C., Fernandez A., Herrmann J., Brisbay S., Tari A.M., Lopez-Berestein G., Lozano G., Sarkiss M., McDonnell T.J. Bcl-2 inhibits p53 nuclear import following DNA damage. Oncogene 1997; 23: 2767–2772
   Google Scholar
• McDonnell T.J., Beham A., Sarkiss M., Andersen M.M., Lo P. Importance of the Bcl-2 family in cell death regulation. Experntia 1996; 52: 1008–1017
   Google Scholar
• Wagner A.J., Kokontis J.M., Hay N. Myc-mediated apoptosis requires wild type p53 in a manner independent of cell cycle arrest and the ability of p53 to induce p21waf1/cip1. Genes & Development 1994; 8: 2817–2830
   PubMed Web of Science ®Google Scholar
• Hermeking H., Eick D. Mediation of c-myc induced apoptosis by p53. Science 1994; 265: 2091–2093
   PubMed Web of Science ®Google Scholar
• Rupnow B.A., Alarcon R.M., Giaccia A.J., Knox S.J. p53 mediates apoptosis induced by c-myc activation in hypoxic or gamma irradiated fibroblasts. Cell Death Differentiation 1998; 5: 141–147
   PubMed Web of Science ®Google Scholar
• Jovanovic S.V., Steenken S., Simic M.G., Hara Y. Flavonoids in Health and Disease, C. Rice-Evans, L. Packer. Marcell Dekker, New York 1998, In
   Google Scholar
• Halliwell B., Cross C.E. Reactive oxygen species, antioxidants and acquired immunodeficiency syndrome. Sense or speculation?. Archives of Internal Medicine 1991; 151: 29–31
   PubMed Web of Science ®Google Scholar
• Bagchi D., Garg A., Korhn R.L., Bagchi M., Tran M.X., Stohs S.J. Oxygen free radical scavenging abilities of vitamin C and E and grape seed proanthocyanidin extract in vitro. Research Communications in Molecular Pathology and Pharmacology 1997; 95: 179–189
   PubMed Web of Science ®Google Scholar
• Bagchi D., Kuszynski C., Balmoori J., Bagchi M., Stohs S.J. Hydrogen peroxide induced modulation of intracellular oxidized states in cultured macrophage J774 A.1 and neuroactive PC-12 cells and protection by a novel IH636 grape seed proanthocyanidin extract. Phytotherapy Research 1998; 12: 568–571
   Google Scholar
• Bagchi D., Garg A., Krohn R.L., Bagchi M., Balmoori J. Protective effects of grape seed proanthocyanidins and selected antioxidants against TPA induced hepatic and brain lipid peroxidation and DNA fragmentation and peritoneal macrophage activation in mice. General Pharmacology 1998; 30: 771–776
   PubMedGoogle Scholar
• Sato M., Maulik G., Ray P.S., Bagchi D., Das D.K. Cardioprotective effects of grape seed proanthocyanidin against ischemic reperfusion injury. Journal of Molecular and Cellular Cardiology 1999; 31: 1289–1297
   PubMed Web of Science ®Google Scholar
• Ray S.D., Kumar M.A., Bagchi D. A novel proanthocyanidin IH636 grape seed extract increases in vivo Bcl-XL expression and prevents acetaminophen-induced programmed and unprogrammed cell death in mouse liver. Archives of Biochemistry and Biophysics 1999; 369: 42–58
   PubMedGoogle Scholar
• Bagchi M., Milnes M., Williams C., Balmoori J., Ye X., Stohs S.J., Bagchi D. Acute and chronic stress-induced oxidative gastrointestinal injury in rats, and the protective ability of a novel grape seed proanthocyanidin extract. Nutrition Research 1999; 19: 1189–1199
   Web of Science ®Google Scholar
• Ye X., Krohn R.L., Liu W., Joshi S.S., Kuszynski C.A., McGinn T.R., Bagchi M., Preuss H.G., Stohs S.J., Bagchi D. The cytotoxic effects of a novel IH636 grape seed proanthocyanidin extract on cultured human cancer cells. Molecular and Cellular Biochemistry 1999; 196: 99–108
   PubMed Web of Science ®Google Scholar
• Bagchi D., Ray S.D., Patel D., Bagchi M. Protection against drug- and chemical-induced multiorgan toxicity by a novel grape seed proanthocyanidin extract. Drugs Under Experimental and Clinical Research 2001; XXVII: 3–14
   Google Scholar
• Joshi S.S., Kuszynski C.A., Benner E.J., Bagchi M., Bagchi D. Amelioration of the cytotoxic effects of chemotherapeutic agents by grape seed proanthocyanidin extract. Antioxidants and Redox Signaling 1999; 65: 55–63
   Google Scholar
• Mosmann T. Rapid colorimetric assay for cellular growth and survival: Application to proliferation and cytotoxicity assays. Journal of Immunological Methods 1983; 65: 55–63
   PubMed Web of Science ®Google Scholar
• Gerlier D., Thomasset N. Use of MTT colorimetric assay to measure cell activation. Journal of Immunological Methods 1986; 94: 57–63
   PubMed Web of Science ®Google Scholar
• Ferrari M., Fornasiero M.C., Isetta A.M. MTT colorimetric assay for testing macrophage cytotoxic activity in vitro. Journal of Immunological Methods 1990; 131: 165–172
   PubMed Web of Science ®Google Scholar
• Bagchi M., Bagchi D., Stohs S.J. In vitro effects of a smokeless tobacco extract on the production of reactive oxygen species by human oral epidermal cells and rat hepatic mitochondria and microsomes and peritoneal macrophages. Archives of Environmental Contamination and Toxicology 1996; 30: 418–422
   PubMed Web of Science ®Google Scholar
• Joshi S.S., Wu A.G., Verbik D.J., Algarra S.M., Bishop M.R., Pirruccello S.J., Iversen P., Jackson J.D., Jr., Kessinger M.A., Sharp J.G. Oligonucleotides complimentary to c-myc messenger RNA inhibit growth and induce apoptosis in human Burkitt lymphoma cells. International Journal of Oncology 1996; 8: 815–820
   PubMed Web of Science ®Google Scholar
• Bagchi D., Tran M.X., Newton S., Bagchi M., Ray S.D., Kuszynski C.A., Stohs S.J. Chromium- and cadmium-induced oxidative stress and apoptosis in cultured J774A.1 macrophage cell. In Vitro Molecular Toxicology 1998; 11: 171–181
   Google Scholar
• Bagchi D., Hassoun E.A.H., Bagchi M., Stohs S.J. Protective effects of free radical scavenger and antioxidants against smokeless tobacco extract (STE)-induced oxidative stress in macrophage J774A.1 cell cultures. Archives of Environmental Contamination and Toxicology 1995; 29: 424–428
   PubMed Web of Science ®Google Scholar
• Choisy-Rossi C., Yonish-Rouach E. Apoptosis and the cell cycle, the p53 connection. Cell Death Differentiation 1998; 5: 129–131
   Google Scholar
• Joshi S.S., Kuszynski C.A., Bagchi M., Bagchi D. Chemopreventive effects of grape seed proanthocyanidin extract on Chang liver cells. Toxicology 2000; 155: 83–90
   PubMed Web of Science ®Google Scholar
• Sen C.K., Bagchi D. Regulation of inducible adhesion molecule expression of human endothelial cells by grape seed proanthocyanidin extract. Molecular and Cellular Biochemistry 2001; 216: 1–7
   PubMed Web of Science ®Google Scholar