Spin trapping agent, phenyl N-tert-butylnitrone, reduces nitric oxide production in the rat brain during experimental meningitis

References

• Moncada S., Palmer R.M.J., Higgs E.A. Nitric oxide: physiology, pathophysiology, and pharmacology. Pharmacological Reviews 1991; 43: 109–142
   PubMed Web of Science ®Google Scholar
• Dawson V.L., Dawson T.M. Physiological and toxicological actions of nitric oxide in the central nervous system. Advances in Pharmacology 1995; 34: 323–342
   PubMedGoogle Scholar
• Griffith O.W., Stuehr D.J. Nitric oxide synthases: properties and catalytic mechanism. Annual Review of Physiology 1995; 57: 707–736
   PubMed Web of Science ®Google Scholar
• Kerwin J.F., Jr., Lancaster J.R., Jr., Feldman P.L. Nitric oxide: a new paradigm for second messengers. Journal of Medicinal Chemistry 1995; 38: 4343–4362
   PubMed Web of Science ®Google Scholar
• Dawson V.L., Dawson T.M. Nitric oxide actions in neurochemistry. Neurochemistry International 1996; 29: 97–110
   PubMed Web of Science ®Google Scholar
• Nathan C. Inducible nitric oxide synthase: What difference does it make?. Journal of Clinical Investigation 1997; 100: 2417–2423
   PubMed Web of Science ®Google Scholar
• Durand M.L., Calderwood S.B., Weber D.J., Miller S.I., Southwick F.S., Caviness V.S., Jr., Swartz M.N. Acute bacterial meningitis in adults. A review of 493 episodes. The New England Journal of Medicine 1993; 328: 21–28
   PubMed Web of Science ®Google Scholar
• Pfister H.-W., Koedel U., Lorenzl S., Tomasz A. Antioxidants attenuate microvascular changes in the early phase of experimental pneumococcal meningitis in rats. Stroke 1992; 23: 1798–1804
   PubMedGoogle Scholar
• Tunkel A.R., Scheld W.M. Pathogenesis and pathophysiology of bacterial meningitis. Annual Review of Medicine 1993; 44: 103–120
   PubMedGoogle Scholar
• Koedel U., Bernatowicz A., Paul R., Frei K., Fontana A., Pfister H-W. Experimental pneumococcal meningitis: cerebrovascular alterations, brain edema, and meningeal inflammation are linked to production of nitric oxide. Annals of Neurology 1995; 37: 313–323
   PubMed Web of Science ®Google Scholar
• Buster B.L., Weintrob A.C., Townsend G.C., Scheld W.M. Potential role of nitric oxide in the pathophysiology of experimental bacterial meningitis in rats. Infection and Immunity 1995; 63: 3835–3839
   PubMed Web of Science ®Google Scholar
• Boje K.M.K. Inhibition of nitric oxide synthase attenuates blood-brain barrier disruption during experimental meningitis. Brain Research 1996; 720: 75–83
   PubMed Web of Science ®Google Scholar
• Kim Y.S., Täuber M.G. Neurotoxicity of glia activated by Gram-positive bacterial products depends on nitric oxide production. Infection and Immunity 1996; 64: 3148–3153
   PubMed Web of Science ®Google Scholar
• Kornelisse R.F., Hoekman K., Visser J.J., Hop W.C., Huijmans J.G., van derStraaten P.J., van der Heijden A.J., Sukhai R.N., Neijens H.J., de Groot R. The role of nitric oxide in bacterial meningitis in children. The Journal of Infectious Diseases 1996; 174: 120–126
   PubMed Web of Science ®Google Scholar
• Leib S.L., Kim Y.S., Black S.M., Tureen J.H., Täuber M.G. Inducible nitric oxide synthase and the effect of aminoguanidine in experimental neonatal meningitis. The Journal of Infectious Diseases 1998; 177: 692–700
   PubMed Web of Science ®Google Scholar
• Suzuki Y., Fujii S., Tominaga T., Yoshimoto T., Fujii S., Akaike T., Maeda H., Yoshimura T. Direct evidence of in vivo nitric oxide production and inducible nitric oxide synthase mRNA expression in the brain of living rat during experimental meningitis. Journal of Cerebral Blood Flow and Metabolism 1999; 19: 1175–1178
   PubMedGoogle Scholar
• Kotake Y. Pharmacological properties of phenyl N-tert-butylnitrone. Antioxidants and Redox Signaling 1999; 1: 481–499
   PubMed Web of Science ®Google Scholar
• Novelli G.P. Oxygen radicals in experimental shock: effects of spin-trapping nitrones in ameliorating shock pathology. Critical Care Medicine 1992; 20: 499–507
   PubMed Web of Science ®Google Scholar
• Pogrebniak H., Mcrino M., Hahn S., Mitchell J., Pass H. Spin trap salvage from endotoxemia: the role of cytokine down-regulation. Surgery 1992; 112: 130–139
   PubMed Web of Science ®Google Scholar
• Miyajima T., Kotake Y. Spin trap N-tert-butylnitrone (PBN) inhibits induction of nitric oxide synthase in endotoxin-induced shock in mice. Biochemical and Biophysical Research Communications 1995; 215: 114–121
   PubMed Web of Science ®Google Scholar
• Miyajima T., Kotake Y. Optimal time and dosage of Phenyl N-tert-butylnitrone (PBN) for the inhibition of nitrix oxide synthase induced in mice. Free Radical Biology and Medicine 1997; 22: 463–470
   PubMed Web of Science ®Google Scholar
• Leib S.L., Kim Y.S., Chow L.L., Sheldon A.R., Täuber M.G. Reactive oxygen intermediates contributes to necrotic and apoptotic neuronal injury in an infant rat model of bacterial meningitis due to group B Streptococci. Journal of Clinical Investigations 1996; 98: 2632–2639
   PubMed Web of Science ®Google Scholar
• Yue T.-L., Gu J.-L., Lysko P.G., Cheng H.-Y., Barone F.C., Feuerstein G. Neuroprotective effects of phenyl-t-butyl-nitrone in gerbil global brain ischemia and in cultured rat cerebellar neurins. Brain Research 1992; 574: 193–197
   PubMed Web of Science ®Google Scholar
• Pazos A.J., Green E.J., Busto R., MaCabe P.M., Baena R.C., Ginsberg M.D., Globus M.Y.-T., Schneiderman N., Dietrich W.D. Effects of combined postischemic hypothermia and delayed N-tert-butyl-α-phenylnitrone (PBN) administration on histopathological and behavioral deficits associated with transient global ischemia in rats. Brain Research 1999; 846: 186–195
   PubMed Web of Science ®Google Scholar
• Kita T., Matsunari Y., Saraya T., Shimada K., O'Hara K., Kubo K., Wagner G.C., Nakashima T. Evaluation of the effects of α-phenyl-N-tert-butylnitrone pretreatment on the neurobehavioral effects of methamphetamine. Life Sciences 2000; 67: 1559–1571
   PubMedGoogle Scholar
• Zausinger S., Hungerhuber E., Baethmann A., Reulen H.-J., Schmid-Elsaesser R. Neurological impairments in rats after transient middle cerebral artery occlusion: a comparative study under various treatment paradigms. Brain Research 2000; 863: 94–105
   PubMed Web of Science ®Google Scholar
• Mordvintcev P., Mülsch A., Busse R., Vanin A.F. On-line detection of nitric oxide formation in liquid aqueous phase by electron paramagnetic resonance spectroscopy. Analytical Biochemistry 1991; 199: 142–146
   PubMed Web of Science ®Google Scholar
• Kotake Y. Continuous and quantitative monitoring of rate of cellular nitric oxide generation. Methods in Enzymology 1996; 268: 222–229
   PubMed Web of Science ®Google Scholar
• Yoshimura T., Yokoyama H., Fujii S. Electron paramagnetic resonance detection and imaging of endogenously synthesized and exogenously supplied nitric oxide. Journal of Magnetic Resonance Analysis 1997; 3: 125–140
   Google Scholar
• Fujii S., Yoshimura T., Kamada H. Nitric Oxide trapping efficiencies of water-soluble iron (III) complexes with dithiocarbamate derivatives. Chemistry Letters 1996; 785–786
   Google Scholar
• Tominaga T., Sato S., Ohnishi T., Ohnishi S.T. Electron paramagnetic resonance detection of nitric oxide produced during forebrain ischemia of the rat. Journal of Cerebral Blood Flow and Metabolism 1994; 14: 715–722
   PubMed Web of Science ®Google Scholar
• Suzuki Y., Fujii S., Numagami Y., Tominaga T., Yoshimoto T., Yoshimura T. In vivo nitric oxide detection in the septic rat brain by electron paramagnetic resonance. Free Radical Research 1998; 28: 293–299
   PubMed Web of Science ®Google Scholar
• Pfister H-W., Koedel U., Haberl R.L., Dirnagl U., Feiden W., Ruckdeschel G., Einhäupl N.M. Microvascular changes during the early phase of pneumococcal meningitis in the rat. Journal of Cerebral Blood Flow and Metabolism 1990; 10: 914–922
   PubMed Web of Science ®Google Scholar
• Boje K.M.K. Inhibition of nitric oxide synthesis partially attenuates alterations in the blood-cerebrospinal fluid barrier during experimental meningitis in the rat. European Journal of Pharmacology 1995; 272: 297–300
   PubMed Web of Science ®Google Scholar
• Sang H., Wallis G.L., Stewart C.A., Kotake Y. Expression of cytokines and activation of transcription factors in lipopolysaccharide-administered rats and their inhibition by phenyl N-tert-butylnitrone (PBN). Archives of Biochemistry and Biophysics 1999; 363: 341–348
   PubMed Web of Science ®Google Scholar
• Schreck R., Reiber P., Baeuerle P.A. Reactive oxygen intermediates as apparently widely used messengers in the activation of the NF-κB transcription factor and HIV-1. The EMBO Journal 1991; 10: 2247–2258
   PubMed Web of Science ®Google Scholar
• Schreck R., Meier B., Männel D.M., Droge W., Baeuerle P.A. Dithiocarbamates as potent inhibitors of nuclear factor κB activation in intact cells. Journal of Experimental Medicine 1992; 175: 1181–1194
   PubMed Web of Science ®Google Scholar