- Spector, A. (1984) "The search for a solution to senile cataracts. Proctor Lecture", Investing. Ophthalmol. Vis. Sci. 25, 130-146.
- Boscia, R, Grattagliano, L, Vendemiale, G., Miscelli-Ferrari, T. and Altomare, E. (2000) "Protein oxidation and lens opacity in humans", Investing. Ophthalmol. Vis. Sci. 41, 2461-2465.
- Hockwin, O. and Ohrloff, C. (1981) "Enzymes in normal, aging and cataractous lenses", In; Bloemendal, H., ed, Molecular and Cellular Biology of the Eye Lens (Wiley, New York), pp 367-413.
- Jacob, T.J. (1999) "The relationship between cataract cell swelling and volume regulation", Prog. Retinal Eye Res. 18, 223-233.
- Schleicher, E.D., Bierhaus, A., Haering, H.-U., Nawroth, P.P. and Lehmann, R. (2001) "Chemistry and pathobiology of advanced glycation end products", Contrib. Nepkrol. 131, 1-9.
- Reddy, V.P., Obrenovich, M.E., Atwood, G.S., Perry, G. and Smith, M.A. (2002) "Involvement of Maillard reactions in Alzheimer disease", Neurotoxicity Res. 4, 191-209.
- Araki, N., Ueno, N., Chakrabarti, B., Morino, Y. and Horiuchi, S. (1992) "Immunochemical evidence for the presence of advanced glycation end products in human lens proteins and its positive correlation with aging", J. Biol. Chem. 267, 10211-10214
- Nagaraj, R.H., Sell, D.R., Prabhakaram, M., Ortwerth, B.J. and Mormier, V.M. (1991) "High correlation between pentosidine protein crosslinks and pigmentation implicates ascorbate oxidation in human lens senescence and cataractogenesis", Proc. Natl Acad. Sci. USA 88, 10257-10261.
- Nagaraj, R.H. and Sady, C. (1996) "The presence of glucose-derived Maillard reaction product in the human lens", FEBS Lett. 382, 234-238.
- Lyons, T.J., Silvestri, G., Dunn, J.A., Dyer, D.G. and Baynes, J.W. (1991) "Role of glycation in modification of lens crystallins in diabetic and nondiabetic senile cataract", Diabetes 40, 1010-1015.
- Frye, E.B., Degenhardt, T.P., Thorpe, S.R. and Baynes, J.W. (1998) "Role of the Maillard reaction in aging of tissue proteins--advanced glycation end product-dependent increase in imidazolium cross-links in human lens proteins", J. Biol. Chem. 273, 18714-18719.
- Lee, K.-W., Meyer, N. and Ortwerth, B.J. (1999) "Chromatographic comparison of the UVA sensitizers present in brunescent cataracts and in calf lens proteins ascorbylated in vitro", Exp. Eye Res. 69, 375-384.
- Ortwerth, B.J., Prabhakaram, M., Nagaraj, R.H. and Linetsky, M. (1997) "The relative UV sensitizer activity of purified advanced glycation endproducts", Photochem. Photobiol. 65, 666-672.
- Nagaraj, R.H. and Monnier, V.M. (1992) "Isolation and characterization of a blue fluorophore from human eye lens crystallins: in vitro formation from Maillard reaction with ascorbate and ribose", Biochim. Biophys. Acta 1116, 34-42.
- Cheng, R., Lin, B., Lee, K.-W. and Ortwerth, B.J. (2001) "Similarity of the yellow chromophores isolated from human cataracts with those from ascorbic acid-modified calf lens proteins: evidence for ascorbic acid glycation during cataract formation", Biochim. Biophys. Acta 1537, 14-26.
- Zhao, W., Devamanoharan, P.S. and Vanna, S.D. (1998) "Fructose induced deactivation of glucose-6-phosphate dehydrogenase activity and its prevention by pyruvate: implications in cataract prevention", Free Radic. Res. 29, 315-320.
- Kawasaki, Y., Fujii, J., Miyazawa, N., Hoshi, A., Okado, A., Tano, Y. and Taniguchi, N. (1998) "Specific detections of the early process of the glycation reaction by fructose and glucose in diabetic rat lens", FEBS Lett. 441, 116-120.
- Thornalley, P.J., Langborg, A. and Minhas, H.S. (1999) "Formation of glyoxal, methylglyoxal and 3-deoxyglucosone in the glycation of proteins by glucose", Biochem. J. 344, 109-116.
- Chellan, P. and Nagaraj, R. (1999) "Protein crosslinking by the Maillard reaction: dicarbonyl-derived imidazolium crosslinks in aging and diabetes", Arch. Biochem. Biophys. 368, 98-104.
- Sady, C., Jiang, C.L., Chellan, P., Madhun, Z., Duve, Y., Glomb, M. and Nagaraj, R.H. (2000) "Maillard reaction by a-oxoaldehydes: detection of glyoxal-modified proteins", Biochim. Biophys. Acta 1481, 255-264
- McLellan, A.C. and Thornalley, P.J. (1992) "Synthesis and chromatography of 1,2-diamino-4,5-diamethoxybenzene,6,7-dimethoxy-2,-methylquinoxaline and 6,7-dimethoxy-2,3-dimethylquinoxaline for use in liquid Chromatographic fluorimetric assay of methylglyoxal", Anal. Chim. Acta 263, 137-142.
- Ahrend, M.H.J. and Bours, J. (1997) "The glycation of bovine lens ßL-ßs-and ?-crystallins demonstrated by isoelectric focusing and lectin staining", Exp. Eye Res. 65, 711-715.
- BOUTS, J. and Ahrend, M.H.J. (1998) "Higher glycation of ßL- and ßs crystalline in the anterior lens cortex and maximum glycation of ?-crystallins in the bovine lens nucleus, demonstrated by frozen-sectioning, isoelectric focusing and lectin staining", Ophthalmic Res. 30, 233-244.
- Breipohl, W., Leyendecker, M., von Tiesenhausen, K. and Grus, F.H. (1995) "Effects of UV-B on the growth pattern of bovine passage I and II lens epithelial cells in vitro", Ophthalmic Res. 27(Suppl. 1), 62-68.
- Linetsky, M. and Ortwerth, B.J. (1996) "Quantitation of the reactive oxygen species generated by the UVA irradiation of ascorbic add-glycated proteins", Photochem. Photobioi. 63, 649-655.
- Linetsky, M. and Ortwerth, B.J. (1997) "Quantitation of the singlet oxygen produced by UVA irradiation of human lens proteins", Photochem. Photobiol. 65, 522-529.
- Aust, S.D. (1987) "In vitro lipid peroxidation", In: Greenwald, R., ed, CRC Handbook of Methods for Oxygen Radical Research (CRC Press, Boca Raton, FL), pp. 204-205.
- Smith, P.K., Krohn, R.I., Hermanson, G.T., Mallia, A.K., Gartner, F.H., Provenzano, M.D., Fujimoto, E.K., Goeke, N.M., Olson, B.J. and Klenk, D.C. (1985) "Measurement of protein using bicinchoninic acid", Anal. Biochem. 150, 76-85.
- Tebbe, B., Wu, S., Geilen, C.C., Eberle, J., Kodelja, V. and Orfanos, C.E. (1997) "L-ascorbic acid inhibits UVA-induced lipid peroxidation and secretion of IL-Ia and IL-6 in cultured human keratinocytes in vitro", J. Investig. Dermatol. 108, 302-306.
- Sidjanin, D., Zigman, S. and Reddan, J. (1993) "DNA damage and repair in rabbit lens epithelial cells following UVA radiation", Curr. Eye Res. 12, 773-781.
- Garland, D.L. (1991) "Ascorbic acid and the eye", Am. J. Clin. Nutr. 54, 1198S-1202S.
- Vile, G.F. and Tyrrell, R.M. (1995) "UVA radiation-induced oxidative damage to lipids and proteins in vitro and in human skin fibrob lasts is dependent on iron and singlet oxygen", Free Radic. Biol. Med. 18, 721-730.
- Shih, M.-K. and Hu, M.-L. (1999) "Relative roles of metal ions and singlet oxygen in UVA-induced liposomal lipid peroxidation", J. Inorg. Biochem. 77, 225-230.
- Zigman, S., Daniel, T., Schultz, J.B., Reddan, J. and Meydani, M. (1995) "Damage to cultured lens epithelial cells of squirrels and rabbits by UV-A (99.9%) plus UV-B (0.1%) radiation and alpha tocopherol protection", Mol. Cell. Biochem. 143, 35-46.
- Andley, U.P., Song, Z., Wawrousek, E.F. and Bassnett, S. (1998) "The molecular chaperone aA-crystallin enhances lens epithelial cell growth and resistance to UVA stress", J. Biol. Chem. 273, 31252-31261.
- Derham, B.K. and Harding, J.J. (1999) "Alpha-crystallin as a molecular chaperone", Prog. Retinal Eye Res. 18, 463-509.
- Giblin, F.J., Chakrapam, B. and Reddy, V.N. (1976) "Gluthathione and lens epithelial function", Investig. Ophthalmol. Vis. Sci. 16, 381-393.
- Pau, H., Graf, P. and Sies, R (1990) "Gutathione levels in human lens: regional distribution in different forms of cataract", Exp. Eye Res. 50, 17-20.
- Augustin, A.A., Dick, H.B., Winkgen, A. and SchmidtErfurth, U. (2001) "Ursache and Prevention oxidativer Schäden des Auges. Eine aktuaelle Bestandsaufnahme", Ophthalmologe 98, 776-797.
Glycated Proteins Can Enhance Photooxidative Stress in Aged and Diabetic Lenses
Reprints and Corporate Permissions
Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?
To request a reprint or corporate permissions for this article, please click on the relevant link below:
Academic Permissions
Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?
Obtain permissions instantly via Rightslink by clicking on the button below:
If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.
Related research
People also read lists articles that other readers of this article have read.
Recommended articles lists articles that we recommend and is powered by our AI driven recommendation engine.
Cited by lists all citing articles based on Crossref citations.
Articles with the Crossref icon will open in a new tab.