Effect of Circulating Forms of Soy Isoflavones on the Oxidation of Low Density Lipoprotein

References

• Anderson, J., Johnstone, B. and Cook-Newell, M. (1995) "Meta-analysis of the effects of soy protein intake on serum lipids", N. Engl. J. Med. 333, 276–282.
   PubMed Web of Science ®Google Scholar
• Ruiz-Larrea, M.B., Mohan, A.R., Paganga, G., Miller, N.J., Bolwell, G.P. and Rice-Evans, C.A. (1997) "Antioxidant activity of phytoestrogenic isoflavones", Free Radic. Res. 26, 63–70.
   PubMed Web of Science ®Google Scholar
• Setchell, K.D. and Cassidy, A. (1999) "Dietary isoflavones: biological effects and relevance to human health", J. Nutr. 129, 758S–767S.
   Google Scholar
• Dubey, R., Gillespie, D., Imthurn, B., Rosselli, M., Jackson, E. and Keller, P. (1999) "Phytoestrogens inhibit growth and MAP-kinase activity in human aortic smooth muscle cells", Hypertension 33, 177–182.
   PubMed Web of Science ®Google Scholar
• Gottstein, N., Ewins, B.A., Ecclestone, C., Hubbard, G.P., Kavanagh, IC., Minihane, A-M., Weinberg, P.D. and Rimbach, G. (2002) "Effect of genistein and daidzein on platelet aggregation and monocyte and endothelial function", Br. J. Nutr. 89, 607–616.
   PubMed Web of Science ®Google Scholar
• Day, A.J., Canada, F.J., Diaz, J.C., Kroon, P.A., Mclauchlan, R., Faulds, C.B., Plumb, G.W., Morgan, M.R. and Williamson, G. (2000) "Dietary flavonoid and isoflavone glycosides are hydrolysed by the lactase site of lactase phlorizin hydrolase", FEBS Lett. 468, 166–170.
   PubMed Web of Science ®Google Scholar
• Setchell, K.D., Brown, N.M., Zimmer-Nechemias, L., Brashear, W.T., Wolfe, B.E., Kirschner, A.S. and Heubi, J.E. (2002) "Evidence for lack of absorption of soy isoflavone glycosides in humans, supporting the crucial role of intestinal metabolism for bioavailability", Am. J. Clin. Nutr. 76, 447–453.
   PubMed Web of Science ®Google Scholar
• Hur, H.G., Beger, R.D., Heinze, T.M., Jr, Lay, J.0., Freeman, J.P., Dore, J. and Rafii, F. (2002) "Isolation of an anaerobic intestinal bacterium capable of cleaving the C-ring of the isoflavonoid daidzein", Arch. Microbiol. 178, 8–12.
   PubMed Web of Science ®Google Scholar
• Lapcik, 0., Hampl, R., Hill, M., Wahala, K., Maharik, N.A. and Adlercreutz, H. (1998) "Radioimmunoassay of free genistein in human serum", J. Steroid Biochem. Mol. Biol. 64, 261–268.
   PubMed Web of Science ®Google Scholar
• Setchell, K.D. (1998) "Phytoestrogens: the biochemistry, physiology, and implications for human health of soy isoflavones", Am. J. Clin. Nutr. 68, 1333S–1346S.
   Google Scholar
• Joannou, G.E., Kelly, G.E., Reeder, A.Y., Waring, M. and Nelson, C. (1995) "A urinary profile study of dietary phytoestrogens. The identification and mode of metabolism of new isoflavonoids", J. Steroid Biochem. Mol. Biol. 54, 167–184.
   PubMed Web of Science ®Google Scholar
• Heinonen, S., Wahala, K. and Adlercreutz, H. (1999) "Identification of isoflavone metabolites dihydrodaidzein, dihydrogenistein, 6'-0H-O-DMA, and cis-4-0H-equol in human urine by gas chromatography-mass spectroscopy using authentic reference compounds", Anal. Biochem. 274, 211–219.
   PubMed Web of Science ®Google Scholar
• Axelson, M. and Setchell, K.D. (1980) "Conjugation of lignans in human urine", FEBS Lett. 122, 49–53.
   PubMed Web of Science ®Google Scholar
• Adlercreutz, H., Fotsis, T., Lampe, J., Wahala, K., Makela, T., Brunow, G. and Hase, T. (1993) "Quantitative determination of lignans and isoflavonoids in plasma of omnivorous and vegetarian women by isotope dilution gas chromatography-mass spectrometry", Scand. J. Clin. Lab. Investig. 215(Suppl.), 5–18.
   Google Scholar
• Morton, M.S., Wilcox, G., Wahlqvist, M.L. and Griffiths, K. (1994) "Determination of lignans and isoflavonoids in human female plasma following dietary supplementation", J. Endocrinol. 142, 251–259.
   PubMed Web of Science ®Google Scholar
• Sfakianos, J., Coward, L., Kirk, M. and Barnes, S. (1997) "Intestinal uptake and biliary excretion of the isoflavone genistein in rats", J. Nutr. 127, 1260–1268.
   PubMed Web of Science ®Google Scholar
• Kulling, S.E., Honig, D., Simat, T.J. and Metzler, M. (2000) "Oxidative in vitro metabolism of the soy phytoestrogens daidzein and genistein", J. Agric. Food Chem. 48, 4963–4972.
   PubMed Web of Science ®Google Scholar
• de Whalley, C.V., Rankin, S.M., Hoult, J.R., Jessup, W. and Leake, D.S. (1990) "Flavonoids inhibit the oxidative modifi-cation of low density lipoproteins by macrophages", Biochem. Pharmacol. 39, 1743–1750.
   PubMed Web of Science ®Google Scholar
• Fairley, B., Botting, N., Coley, J. and Cassidy, A. (2003) "Synthesis of daidzein sulphates", Tetrahedron, 59,5407–5410.
   Web of Science ®Google Scholar
• Schacterle, G.R. and Pollack, R.L. (1973) "A simplified method for the quantitative assay of small amounts of protein in biological material", Anal. Biochem. 51, 654–655.
   PubMed Web of Science ®Google Scholar
• Esterbauer, H., Striegl, G., Puhl, H. and Rotheneder, M. (1989) "Continuous monitoring of in vitro oxidation of human low density lipoprotein", Free Radic. Res. Commun. 6, 67–75.
   PubMed Web of Science ®Google Scholar
• Adlercreutz, H., van der Wildt, J., Kinzel, J., Attalla, H., Wahala, K., Makela, T., Hase, T. and Fotsis, T. (1995) "Lignan and isoflavonoid conjugates in human urine", J. Steroid Biochem. Mol. Biol. 52, 97–103.
   PubMed Web of Science ®Google Scholar
• Steinberg, D., Parthasarathy, S., Carew, T.E., Khoo, J.C. and Witztum, J.L. (1989) "Beyond cholesterol modifications of low-density lipoprotein that increase its atherogenicity", N. Engl. J. Med. 320, 915–924.
   PubMed Web of Science ®Google Scholar
• Steinberg, D. and Witztum, J.L. (2002) "Is the oxidative modification hypothesis relevant to human atherosclerosis? Do the antioxidant trials conducted to date refute the hypothesis?", Circulation 105, 2107–2111.
   PubMed Web of Science ®Google Scholar
• Esterbauer, H., Waeg, G., Puhl, H., Dieber-Rotheneder, M. and Tatzber, F. (1992) "Inhibition of LDL oxidation by anti-oxidants", EXS 62, 145–157.
   PubMedGoogle Scholar
• Lamb, D.J., Mitchinson, M.J. and Leake, D.S. (1995) "Transition metal ions within human atherosclerotic lesions can catalyse the oxidation of low density lipoprotein by macrophages", FEBS Lett. 374, 12–16.
   PubMed Web of Science ®Google Scholar
• Wei, H., Bowen, R., Cai, Q., Barnes, S. and Wang, Y. (1995) "Antioxidant and antipromotional effects of the soybean isoflavone genistein", Proc. Soc. Exp. Biol. Med. 208, 124–130.
   PubMed Web of Science ®Google Scholar
• Arora, A., Nair, M.G. and Strasburg, G.M. (1998) "Anti-oxidant activities of isoflavones and their biological meta-bolites in a liposomal system", Arch. Biochem. Biophys. 356, 133–141.
   PubMed Web of Science ®Google Scholar
• Hodgson, J.M., Croft, K.D., Puddey, I.B., Morey, T.A. and Beilin, L.J. (1996) "Soybean isoflavonoids and their metabolic products inhibit in vitro lipoprotein oxidation in serum", J. Nutr. Biochem. 7, 664–669.
   Web of Science ®Google Scholar
• Rimbach, G.H., Matsugo, S., Ewins, B.A., Vafeidou, K., Turner, R., de Pascual Teresa, S., Minihane, A.M. and Weinberg, P.D. (2003) "Antioxidant and free radical scaven-ging activity of isoflavone metabolites", Xenobiotica 33, 913–925.
   PubMed Web of Science ®Google Scholar
• Wiseman, H., O'Reilly, J.D., Adlercreutz, H., Mallet, Al., Bowey, E.A., Rowland, I.R. and Sanders, T.A. (2000) "Isoflavone phytoestrogens consumed in soy decrease F(2)-isoprostane concentrations and increase resistance of low-density lipoprotein to oxidation in humans", Am. J. Clin. Nutr. 72, 395–400.
   PubMed Web of Science ®Google Scholar