146
Views
28
CrossRef citations to date
0
Altmetric
Original Article

Phosphate Increases Mitochondrial Reactive Oxygen Species Release

&
Pages 1113-1118 | Received 20 Jun 2004, Published online: 07 Jul 2009

References

  • Kowaltowski, A.J. and Vercesi, A.E. (1999) "Mitochondrial damage induced by conditions of oxidative stress", Free Radic. Biol. Med. 26, 463–471.
  • Cadenas, E. and Davies, K.J. (2000) "Mitochondrial free radical generation, oxidative stress, and aging", Free Radic. Biol. Med. 29, 222–230.
  • Lenaz, G. (2001) "The mitochondrial production of reactive oxygen species: mechanisms and implications in human pathology", IUBMB Life 52, 159–164.
  • Turrens, J.F. (2003) "Mitochondrial formation of reactive oxygen species", J. Physiol. 552, 335–344.
  • Vanden Hoek, T.L., Becker, L.B., Shao, Z., Li, C.Q. and Schumacker, P.T. (1998) "Reactive oxygen species released from mitochondria during brief hypoxia induce preconditioning in cardiomyocytes", J. Biol. Chem. 273, 18092–18098.
  • da Silva, M.M., Sartori, A., Belisle, E. and Kowaltowski, A.J. (2003) "Ischemic preconditioning inhibits mitochondrial respiration, increases H202 release, and enhances K+ transport", Am. J. Physiol. 285, H154—H162.
  • Vanden Hoek, T.L., Becker, L.B., Shao, Z.H., Li, C.Q. and Schumacker, P.T. (2000) "Preconditioning in cardiomyocytes protects by attenuating oxidant stress at reperfusion", Circ. Res. 86, 541–548.
  • Ferranti, R., da Silva, M.M. and Kowaltowski, A.J. (2003) "Mitochondrial ATP-sensitive K+ channel opening decreases reactive oxygen species generation", FEBS Lett. 536, 51–55.
  • Barja, G. (1999) "Mitochondrial oxygen radical generation and leak: sites of production in states 4 and 3, organ specificity, and relation to aging and longevity", J. Bioenerg. Biomembr. 31, 347–366.
  • Fiskum, G., Starkov, A.A., Polster, B.M. and Chinopoulos, C. (2003) "Mitochondrial mechanisms of neural cell death and neuroprotective interventions in Parkinson's disease", Ann. N.Y. Acad. Sci. 991, 111–119.
  • Nicholls, D.G. and Ferguson, S.J. (2002) Bioenergetics 3. (Academic Press, London).
  • Korshunov, S.S., Skulachev, V.P. and Starkov, A.A. (1997) "High protonic potential actuates a mechanism of production of reactive oxygen species in mitochondria", FEBS Lett. 416, 15–18.
  • Korshunov, S.S., Korkina, 0.V., Ruuge, E.K., Skulachev, V.P. and Starkov, A.A. (1998) "Fatty acids as natural uncouplers preventing generation of 02 and H202 by mitochondria in the resting state", FEBS Lett. 435, 215–218.
  • Negre-Salvayre, A., Hirtz, C., Carrera, G., Cazenave, R., Troly, M., Salvayre, R., Penicaud, L. and Casteilla, L. (1997) "A role for uncoupling protein-2 as a regulator of mitochondrial hydrogen peroxide generation", FASEB J. 11, 809–815.
  • Kowaltowski, A.J., Costa, A.D.T. and Vercesi, A.E. (1998) "Activation of the potato plant uncoupling mitochondrial protein inhibits reactive oxygen species generation by the respiratory chain", FEBS Lett. 425, 213–216.
  • Ruy, F., Vercesi, A.E., Andrade, P.B.M., Bianconi, M.L., Chaimovich, H. and Kowaltowski, A.J. (2004) "A highly active ATP-insensitive K+ import pathway in plant mito-chondria", J. Bioenerg. Biomembr. 36, 195–202.
  • Murphy, M.P., Echtay, KS., Blaikie, F.H., Asin-Cayuela, J., Cocheme, H.M., Green, K., Buckingham, J.A., Taylor, E.R., Hurrell, F., Hughes, G., Miwa, S., Cooper, C.E., Svistunenko, D.A., Smith, R.A. and Brand, M.D. (2003) "Superoxide activates uncoupling proteins by generating carbon-centered radicals and initiating lipid peroxidation: studies using a mitochondria-targeted spin trap derived from alpha-phenyl-N-tert-butylnitrone", J. Biol. Chem. 278, 48534–48545.
  • Skulachev, V.P. (1997) "Membrane-linked systems preventing superoxide formation", Biosci. Rep. 17, 347–366.
  • Kaplan, R.S., Pratt, R.D. and Pedersen, P.L. (1986) "Purification and characterization of the reconstitutively active phosphate transporter from rat liver mitochondria", J. Biol. Chem. 261, 12767–12773.
  • Garlid, K.D., Dos Santos, P., Xie, Z.J., Costa, A.D.T. and Paucek, P. (2003) "Mitochondrial potassium transport: the role of the mitochondrial ATP-sensitive K+ channel in cardiac function and cardioprotection", Biochim. Biophys. Acta 1606, 1–21.
  • Kowaltowski, A.J., Castilho, R.F., Grijalba, M.T., Bechara, E.J. and Vercesi, A.E. (1996) "Effect of inorganic phosphate concentration on the nature of inner mitochondrial mem-brane alterations mediated by Ca2+ ions. A proposed model for phosphate-stimulated lipid peroxidation", J. Biol. Chem. 271, 2929–2934.
  • Kowaltowski, A.J., Seetharaman, S., Paucek, P. and Garlid, K.D. (2001) "Bioenergetic consequences of opening the ATP-sensitive K+ channel of heart mitochondria", Am. J. Physiol. 280, H649—H657.
  • Zhou, M. and Panchuk-Voloshina, N. (1997) "A one-step fluorometric method for the continuous measure-ment of monoamine oxidase activity", Anal. Biochem. 253, 169–174.
  • Ikkerman, K.E. and Wikstrom, M.K. (1976) "Safranine as a probe of the mitochondria' membrane potential", FEBS Lett. 68, 191–197.
  • Kowaltowsld, A.J., Cosso, R.G., Campos, C.B. and Fiskum, G. (2002) "Effect of Bc1-2 overexpression on mitochondrial structure and function", J. Biol. Chem. 277, 42802–42807.
  • Grijalba, M.T., Andrade, P.B., Meinicke, A.R., Castilho, RE, Vercesi, A.E. and Schreier, S. (1998) "Inhibition of membrane lipid permddation by a radical scavenging mechanism: a novel function for hydroxyl-containing ionophores", Free Radic. Res. 28, 301–318.
  • Zoratti, M. and Szabo, I. (1995) "The mitochondria' per-meability transition", Biochim. Biophys. Acta 1241, 139–176.
  • Kowaltowski, A.J., Castilho, R.F. and Vercesi, A.E. (2001) "Mitochondria' permeability transition and oxidative stress", FEBS Lett. 425, 12–15.

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.