Melatonin does not React Rapidly with Hydrogen Peroxide

References

• Reiter, R.J., Tan, DX., Manchester, L.C. and Qi, W. (2001) "Biochemical reactivity of melatonin with reactive oxygen and nitrogen species: a review of the evidence", Cell Biochem. Biophys. 34, 237–256.
   PubMed Web of Science ®Google Scholar
• Reiter, R.J., Tan, DX., Cabrera, J., D'Arpa, D., Sainz, R.M., Mayo, J.C. and Ramos, S. (1999) "The oxidant/antioxidant network: role of melatonin", Biol. Signals Recept. 8, 56–63.
   PubMedGoogle Scholar
• Reiter, R.J., Tan, D.X., Osuna, C. and Gitto, E. (2000) "Actions of melatonin in the reduction of oxidative stress. A review", J. Biomed. Sci. 7, 444–458.
   PubMed Web of Science ®Google Scholar
• Reiter, R.J., Acuna-Castroviejo, D., Tan, D.X. and Burkhardt, S. (2001) "Free radical-mediated molecular damage. Mechan-isms for the protective actions of melatonin in the central nervous system", Ann. N.Y. Acad. Sci. 939, 200–215.
   PubMed Web of Science ®Google Scholar
• Tan, DX., Reiter, R.J., Manchester, L.C., Yan, M.T., El-Sawi, M., Sainz, R.M., Mayo, J.C., Kohen, R., Allegra, M. and Hardeland, R. (2002) "Chemical and physical properties and potential mechanisms: melatonin as a broad spectrum antioxidant and free radical scavenger", Curr. Top. Med. Chem. 2, 181–197.
   PubMedGoogle Scholar
• Reiter, R.J. (2000) "Melatonin: Lowering the High Price of Free Radicals", News Physiol. Sci. 15, 246–250.
   PubMedGoogle Scholar
• Zhang, H., Squadrito, G.L., Uppu, R. and Pryor, W.A. (1999) "Reaction of peroxynitrite with melatonin: A mechanistic study", Chem. Res. Toxicol. 12, 526–534.
   PubMed Web of Science ®Google Scholar
• Nohl, H. and Staniek, K. (1997) "1st Melatonin emn Antioxidanz?", Wien. Klin. Wochenschr. 109, 737–740.
   PubMed Web of Science ®Google Scholar
• Zang, L.-Y, Cosma, G., Gardner, H. and Vallyathan, V. (1998) "Scavenging of reactive oxygen species by melatonin", Biochim. Biophys. Acta 1425, 469–477.
   PubMed Web of Science ®Google Scholar
• Tan, D.-X., Manchester, L.C., Reiter, R.J., Plummer, B.F., Limson, J., Weintraub, S.T. and Qi, W. (2000) "Melatonin directly scavenges hydrogen peroxide: a potentially bew metabolic pathway of melatonin biotransformation", Free Radic. Biol. Med. 29, 1177–1185.
   PubMed Web of Science ®Google Scholar
• Burkhardt, S., Reiter, R.J., Tan, D.X., Hardeland, R., Cabrera, J. and Karbownik, M. (2001) "DNA mddatively damaged by chromium(11) and H(2)0(2) is protected by the anti-oxidants melatonin, N(1)-acetyl-N(2)-formy1-5-methoxy-kynuramine, resveratrol and uric acid", Int. J. Biochem. Cell Biol. 33, 775–783.
   PubMed Web of Science ®Google Scholar
• Ortega-Gutierrez, S., Garcia, J.J., Martinez-Ballarin, E., Reiter, R.J., Millan-Plano, S., Robinson, M. and Acuna-Castroviejo, D. (2002) "Melatonin improves deferoxamine antioxidant activity in protecting against lipid peroxidation caused by hydrogen peroxide in rat brain homogenates", Neurosci. Lett. 323, 55–59.
   PubMed Web of Science ®Google Scholar
• Pick, E. and Keisari, Y. (1980) "A simple colorimetric method for the measurement of hydrogen peroxide produced by cells in culture", J. Immunol. Meth. 38, 161–170.
   PubMed Web of Science ®Google Scholar
• Gay, C. and Gebicki, J.M. (2000) "A critical evaluation of the effect of sorbitol on the ferric-xylenol orange hydropermdde assay", Anal. Biochem. 284, 217–220.
   PubMed Web of Science ®Google Scholar
• Bartosz, G. (2003) Druga twarz tlenu. Wolne rodniki w przyrodzie [The other face of oxygen. Free radicals in the nature] (Polish Scientific Publishers, Warsaw).
   Google Scholar
• Halliwell, B. and Gutteridge, J.M.C. (1999) Free Radicals in Biology and Medicine (Oxford University Press, Oxford, New York).
   Google Scholar
• de Oliveira Silva, S., Ximenes, V.F., Catalani,L.H. and Campa, A. (2000) "Myelopermddase-catalyzed oxidation of melatonin by activated neutrophils", Biochem. Biophys. Res. Commun. 279, 657–662.
   Web of Science ®Google Scholar
• Ximenes, V.F., Catalani, L.H. and Campa, A. (2001) "Oxidation of melatonin and tryptophan by an HRP cycle involving compound 111", Biochem. Biophys. Res. Commun. 287, 130–134.
   PubMed Web of Science ®Google Scholar
• Jantschko, W., Furtmuller, P.C., Allegra, M., Livrea, MA., Jakopitsch, C., Regelsberger, G. and Obinger, C. (2002) "Redox intermediates of plant and mammalian peroxidases: a comparative transient-kinetic study of their reactivity toward indole derivatives", Arch. Biochem. Biophys. 398, 12–22.
   PubMed Web of Science ®Google Scholar
• Hermes-lima, M., Willmore, W.G. and Storey, KB. (1995) "Quantification of lipid peroxidation in tissue extracts based on Fe(11)xylenol orange complex formation", Free Radic. Biol. Med. 19, 271–280.
   PubMed Web of Science ®Google Scholar
• Reiter, R.J., Burkhardt, S., Cabrera, J. and Garcia, J.J. (2002) "Beneficial neurobiological effects of melatonin under conditions of increased oxidative stress", Curr. Med. Chem. — Central Nervous System Agents 2, 45–58.
   Google Scholar