Oxidative DNA damage in cultured fibroblasts from patients with hereditary glutathione synthetase deficiency

References

• Beyer RE. The participation of coenzyme Q in free radical production and antioxidation. Free Radic Biol Med 1990;8:545–565.
   PubMed Web of Science ®Google Scholar
• Bains JS, Shaw CA. Neurodegenerative disorders in humans: The role of glutathione in oxidative stress-mediated neuronal death. Brain Res Rev 1997;25:335–358.
   PubMed Web of Science ®Google Scholar
• Stadtman ER, Levine RL. Protein oxidation. Ann NY Acad Sci 2000;899:191–208.
   PubMed Web of Science ®Google Scholar
• Droge W. Free radicals in the physiological control of cell function. Physiol Rev 2002;82:47–95.
   PubMed Web of Science ®Google Scholar
• Harman D. Aging: A theory based on free radical and radiation chemistry. J Gerontol 1956;11:298–300.
   PubMedGoogle Scholar
• Ames BN. Endogenous oxidative DNA damage, aging, and cancer. Free Radic Res Commun 1989;7:121–128.
   PubMed Web of Science ®Google Scholar
• Dizdaroglu M. Chemical determination of free radical-induced damage to DNA. Free Radic Biol Med 1991;10:225–242.
   PubMed Web of Science ®Google Scholar
• Adelman R, Saul RL, Ames BN. Oxidative damage to DNA: Relation to species metabolic rate and life span. Proc Natl Acad Sci USA 1988;85:2706–2708.
   Google Scholar
• Larsson A, Ristoff E, Anderson M. Glutathione synthetase deficiency and other disorders of the gamma-glutamyl cycle. In: Scriver CF, Beavdet AL, Sly WS, Valle D, editors. The metabolic and molecular bases of inherited disease. 8th ed. New York: McGraw Hill; 2001. p 2205–2216 Available: http://genetics.accessmedicine.com.
   Google Scholar
• Hutchinson F. Sulfhydryl groups and the oxygen effect on irradiated dilute solutions of enzymes and nucleic acids. Radiat Res 1961;14:721–731.
   PubMed Web of Science ®Google Scholar
• Polekhina G, Board PG, Gali RR, Rossjohn J, Parker MW. Molecular basis of glutathione synthetase deficiency and a rare gene permutation event. EMBO J 1999;18:3204–3213.
   Google Scholar
• Whitbread L, Gali RR, Board PG. The structure of the human glutathione synthetase gene. Chem Biol Interact 1998;:111–112, 35–40.
   Google Scholar
• Gali RR, Board PG. Sequencing and expression of a cDNA for human glutathione synthetase. Biochem J 1995;310:353–358.
   PubMed Web of Science ®Google Scholar
• Ristoff E, Mayatepek E, Larsson A. Long-term clinical outcome in patients with glutathione synthetase deficiency. J Pediatr 2001;139:79–84.
   Google Scholar
• Dringen R. Metabolism and functions of glutathione in brain. Prog Neurobiol 2000;62:649–671.
   PubMed Web of Science ®Google Scholar
• Olive PL, Wlodek D, Durand RE, Banath JP. Factors influencing DNA migration from individual cells subjected to gel electrophoresis. Exp Cell Res 1992;198:259–267.
   PubMed Web of Science ®Google Scholar
• Yang Y, Griffiths WJ, Nordling M, Nygren J, Moller L, Bergman J, Liepinsh E, Otting G, Gustafsson JA, Rafter J, Sjovall J. Ring opening of benzo [a]pyrene in the germ-free rat is a novel pathway for formation of potentially genotoxic metabolites. Biochemistry 2000;39:15585–15591.
   Google Scholar
• Olive PL, Banath JP, Durand RE. Heterogeneity in radiatio-n-induced DNA damage and repair in tumor and normal cells measured using the comet assay. Radiat Res 1990;122:86–94.
   Google Scholar
• Boiteux S, Gajewski E, Laval J, Dizdaroglu M. Substrate specificity of the Escherichia coli Fpg protein (formamido-pyrimidine-DNA glycosylase): Excision of purine lesions in DNA produced by ionizing radiation or photosensitization. Biochemistry 1992;31:106–110.
   PubMed Web of Science ®Google Scholar
• ESCODD (European Standards Committee on Oxidative DNA Damage). Comparative analysis of baseline 8-oxo-7,8-dihydroguanine in mammalian cell DNA, by different methods in different laboratories: An approach to consensus. Carcinogenesis 2002;23:2129–2133.
   PubMed Web of Science ®Google Scholar
• Dandona P, Thusu K, Cook S, Snyder B, Makowski J, Armstrong D, Nicotera T. Oxidative damage to DNA in diabetes mellitus. Lancet 1996;347:444–445.
   Google Scholar
• Tsuchida M, Miura T, Mizutani K, Aibara K. Fluorescent substances in mouse and human sera as a parameter of in vivo lipid peroxidation. Biochim Biophys Acta 1985;834:196–204.
   PubMed Web of Science ®Google Scholar
• Skullerud K, Marstein S, Schrader H, Brundelet PJ, Jellum E. The cerebral lesions in a patient with generalized glutathione deficiency and pyroglutamic aciduria (5-oxoprolinuria). Acta Neuropathol 1980;52: 235–238.
   Google Scholar
• Myhre 0, Bjugan B, Fonnum F. Toxic effect of L-2-chloropropionate on cultured rat cerebellar granule cells is ameliorated after inhibition of reactive oxygen species formation. J Neurosci Res 2001;66: 992–997.
   Google Scholar
• Wyatt I, Gyte A, Simpson MG, Widdowson PS, Lock EA. The role of glutathione in L-2-chloropropionic acid induced cerebellar granule cell necrosis in the rat. Arch Toxicol 1996;70: 724–735.
   Google Scholar
• Ristoff E, Hebert C, Njalsson R, Norgren S, Rooyackers 0, Larsson A. Glutathione synthetase deficiency: Is gamma-glutamylcysteine accumulation a way to cope with oxidative stress in cells with insufficient levels of glutathione? J Inherit Metab Dis 2002;25:577–584.
   Google Scholar
• Ljungman M, Nyberg S, Nygren J, Eriksson M, Ahnstrom G. DNA-bound proteins contribute much more than soluble intracellular compounds to the intrinsic protection against radiation-induced DNA strand breaks in human cells. Radiat Res 1991;127:171–176.
   Google Scholar
• Nygren J, Ljungman M, Ahnstrom G. Chromatin structure and radiation-induced DNA strand breaks in human cells: Soluble scavengers and DNA-bound proteins offer a better protection against single- than double-strand breaks. Int J Radiat Biol 1995;68:11–18.
   Google Scholar
• Ljungman M, Hanawalt PC. Efficient protection against oxidative DNA damage in chromatin. Mol Carcinog 1992;5:264–269.
   PubMed Web of Science ®Google Scholar
• Biaglow JE, Varnes ME, Tuttle SW, Oleinick NL, Glazier K, Clark EP, Epp ER, Dethlefsen LA. The effect of L-buthionine sulfoximine on the aerobic radiation response of A549 human lung carcinoma cells. Int J Radiat Oncol Biol Phys 1986;12:1139–1142.
   PubMed Web of Science ®Google Scholar
• Petersen AB, Gniadecki R, Vicanova J, Thorn T, Wulf HC. Hydrogen peroxide is responsible for UVA-induced DNA damage measured by alkaline comet assay in Ha C aT keratinocytes. J Pho to chem Ph o tob io 1 B 2000;59: 123–131.
   Google Scholar
• Carnevali S, Petruzzelli S, Longoni B, Vanacore R, Barale R, Cipollini M, Scatena F, Paggiaro P, Celi A, Giuntini C. Cigarette smoke extract induces oxidative stress and apoptosis in human lung fibroblasts. Am J Physiol Lung Cell Mol Physiol 2003;284:L955—L963.
   Web of Science ®Google Scholar
• Beddowes EJ, Faux SP, Chipman JK. Chloroform, carbon tetrachloride and glutathione depletion induce secondary genotoxicity in liver cells via oxidative stress. Toxicology 2003;187:101–115.
   Google Scholar
• Sasaki MS, Matsubara S. Free radical scavenging in protection of human lymphocytes against chromosome aberration formation by gamma-ray irradiation. Int J Radiat Biol Relat Stud Phys Chem Med 1977;32:439–445.
   PubMed Web of Science ®Google Scholar