146
Views
29
CrossRef citations to date
0
Altmetric
Original

ROS and protein oxidation in early stages of cytotoxic drug induced apoptosis

, &
Pages 1124-1137 | Received 24 Mar 2006, Published online: 07 Jul 2009

References

  • Fisher D. Apoptosis in cancer therapy: Crossing the threshold. Cell 1994; 78: 539–542
  • Herr I, Debatin KM. Cellular stress response and apoptosis in cancer therapy. Blood 2001; 98(9)2603–2614
  • Armstrong SC. Anti-oxidants and apoptosis: Attenuation of doxorubicin induced cardiomyopathy by carvedilol. J Mol Cell Cardiol 2004; 37(4)817–821
  • Ma YS, Chao CC, Stadtman ER. Oxidative modification of glutamine synthetase by 2,2′-azobis(2-amidinopropane) dihydrochloride. Arch Biochem Biophys 1999; 363(1)129–134
  • Troyano A, Fernandez C, Sancho P, de Plas E, Aller P. Effect of glutathione depeation on antitumour drug toxicity (apoptosis and necrosis) in U-937 human promonocytic cells—the role of intracellular oxidation. J Biol Chem 2001; 276(50)47107–47115
  • Gorman A, McGowan A, Cotter TG. Role of peroxide and superoxide anion during tumour cell apoptosis. FEBS Lett 1997; 404(1)27–33
  • Mizutani H, Tada-Oikawa S, Hiraku Y, Kojima M, Kawanishi S. Mechanism of apoptosis induced by doxorubicin through the generation of hydrogen peroxide. Life Sci 2005; 76(13)1439–1453
  • Wang SW, Konorev EA, Kotamraju S, Joseph J, Kalivendi S, Kalyanaraman B. Doxorubicin induces apoptosis in normal and tumor cells via distinctly different mechanisms—intermediacy of H2O2- and p53-dependent pathways. J Biol Chem 2004; 279(24)25535–25543
  • Tsang WP, Chau SPY, Kong SK, Fung KP, Kwok TT. Reactive oxygen species mediate doxorubicin induced p53-independent apoptosis. Life Sci 2003; 73(16)2047–2058
  • Kang YJ, Zhou ZX, Wang GW, Buridi A, Klein JB. Suppression by metallothionein of doxorubicin-induced cardiomyocyte apoptosis through inhibition of p38 mitogen-activated protein kinases. J Biol Chem 2000; 275(18)13690–13698
  • Stadheim TA, Kucera GL. c-Jun N-terminal kinase/stress-activated protein kinase (JNK/SAPK) is required for mitoxantrone- and anisomycin-induced apoptosis in HL-60 cells. Leuk Res 2002; 26(1)55–65
  • Wang L, Chen L, Benincosa J, Fortney J, Gibson LF. VEGF-induced phosphorylation of Bcl-2 influences B lineage leukemic cell response to apoptotic stimuli. Leukemia 2005; 19(3)344–353
  • Colussi C, Albertini MC, Coppola S, Rovidati S, Galli F, Ghibelli L. H2O2-induced block of glycolysis as an active ADP-ribosylation reaction protecting cells from apoptosis. FASEB J 2000; 14(14)2266–2276
  • Scovassi AI, Poirier GG. Poly(ADP-ribosylation) and apoptosis. Mol Cell Biochem 1999; 199(1–2)125–137
  • Ghibelli L, Nosseri C, Coppola S, Maresca V, Dini L. The increase in H2O2-induced apoptosis by ADP-ribosylation inhibitors is related to cell blebbing. Exp Cell Res 1995; 221(2)470–477
  • Monteiro H, Tsujita M, Arai R, Stern A. Ras nitrosylation and protein phosphorylation in nitric oxide-induced apoptosis. Free Radic Biol Med 2003; 35: S70–S71
  • Tenneti L, Demilia DM, Lipton SA. Suppression of neuronal apoptosis by S-nitrosylation of caspases. Neurosci Lett 1997; 236(3)139–142
  • Melino G, Bernassola F, Knight RA, Corasaniti MT, Nistico G, FinazziAgro A. S-nitrosylation regulates apoptosis. Nature 1997; 388(6641)432–433
  • England K, O'Driscoll C, Cotter TG. Carbonylation of glycolytic proteins is a key response to drug induced oxidative stress and apoptosis. Cell Death Differ 2004; 11: 252–260
  • England K, Cotter T. Identification of carbonylated proteins by MALDI-TOF mass spectroscopy reveals susceptibility of ER. Biochem Biophys Res Commun 2004; 320(1)123–130
  • Melino G, Catani MV, Corazzari M, Guerrieri P, Bernassola F. Nitric oxide can inhibit apoptosis or switch it into necrosis. Cell Mol Life Sci 2000; 57(4)612–622
  • Fucci L, Oliver CN, Coon MJ, Stadtman ER. Inactivation of key metabolic enzymes by mixed-function oxidation reactions: Possible implication in protein turnover and ageing. Proc Natl Acad Sci USA 1983; 80: 1521–1525
  • Levine RL, Garland D, Oliver CN, Amici A, Climent I, Lenz A-G, Ahn BW, Shaltiel S, Stadtman ER. Determination of carbonyl content in oxidatively modified proteins. Methods Enzymol 1990; 186: 464–478
  • Ellgaard L, Ruddock LW. The human protein disulphide isomerase family: Substrate interactions and functional properties. EMBO Rep 2005; 6(1)28–32
  • Frand AR, Cuozzo JW, Kaiser CA. Pathways for protein disulphide bond formation. Trends Cell Biol 2000; 10(5)203–210
  • Ferrari DM, Soling HD. The protein disulphide-isomerase family: Unravelling a string of folds. Biochem J 1999; 339: 1–10
  • Tanaka Y, Gavrielides MV, Mitsuuchi Y, Fujii T, Kazanietz MG. Protein kinase C promotes apoptosis in LNCaP prostate cancer cells through activation of p38 MAPK and inhibition of the Akt survival pathway. J Biol Chem 2003; 278(36)33753–33762
  • Tamagno E, Robino G, Obbili A, Bardini P, Aragno M, Parola M, Danni O. H2O2 and 4-hydroxynonenal mediate amyloid beta-induced neuronal apoptosis by activating JNKs and p38(MAPK). Exp Neurol 2003; 180(2)144–155
  • Kondoh M, Tasaki E, Araragi S, Takiguchi M, Higashimoto M, Watanabe Y, Sato M. Requirement of caspase and p38(MAPK) activation in zinc-induced apoptosis in human leukemia HL-60 cells. Eur J Biochem 2002; 269(24)6204–6211
  • Alvarado-Kristensson M, Andersson T. Protein phosphatase 2A regulates apoptosis in neutrophils by dephosphorylating both p38 MAPK and its substrate caspase 3. J Biol Chem 2005; 280(7)6238–6244
  • Perfettini JL, Castedo M, Nardacci R, Ciccosanti F, Boya P, Roumier B, Larochette N, Piacentini M, Kroemer G. Essential role of p53 phosphorylation by p38 MAPK in apoptosis induction by the HIV-1 envelope. J Exp Med 2005; 201(2)279–289
  • Rao RV, Ellerby HM, Bredesen DE. Coupling endoplasmic reticulum stress to the cell death program. Cell Death Differ 2004; 11(4)372–380
  • Carmody RJ, Cotter TG. Signalling apoptosis:a radical approach. Redox Rep 2001; 6(2)77–90
  • McGowan AJ, Fernandes RS, Samali A, Cotter TG. Anti-oxidants and apoptosis. Biochem Soc Trans 1996; 24: 299–303
  • Lown JW, Chen HH, Plambeck JA, Acton EM. Further studies on the generation of reactive oxygen species from activated anthracyclines and the relationship to cytotoxic action and cardiotoxic effects. Biochem Pharmacol 1982; 31: 575–581
  • Chevion M, Berenshtein E, Stadtman ER. Human studies related to protein oxidation: Protein carbonyl content as a marker of damage. Free Radic Res 2000; 33: S99–S108
  • Wondrak GT, Cervantes-Laurean D, Jacobson EL, Jacobson MK. Histone carbonylation in vivo and in vitro. Biochem J 2000; 351: 769–777
  • Berlett BS, Stadtman ER. Protein oxidation in aging, disease, and oxidative stress. J Biol Chem 1997; 272(33)20313–20316
  • Stadtman ER. Role of oxidized amino-acids in protein breakdown and stability, in redox-active amino acids in biology. Redox-active amino-acids in biology. 1995; 379–393
  • Dean RT, Fu SL, Stocker R, Davies MJ. Biochemistry and pathology of radical-mediated protein oxidation. Biochem J 1997; 324: 1–18
  • Stadtman ER, Berlett BS. Reactive oxygen mediated protein oxidation in aging and disease. Reactive oxygen species in biological systems, C Colton, DJ Gilbert. Kluwer Academic/Plenum Publishers, New York 1999; 657–675
  • Burcham PC, Kuhan YT. Diminished susceptibility to proteolysis after protein modification by the lipid peroxidation product malondialdehyde: Inhibitory role for crosslinked and noncrosslinked adducted proteins. Arch Biochem Biophys 1997; 340(2)331–337
  • Cabiscol E, Belli G, Tamarit J, Echave P, Herrero E, Ros J. Mitochondrial Hsp60, resistance to oxidative stress, and the labile iron pool are closely connected in Saccharomyces cerevisiae. J Biol Chem 2002; 277(46)44531–44538
  • Tamarit J, Cabiscol E, Ros J. Identification of the major oxidatively damaged proteins in Escherichia coli cells exposed to oxidative stress. J Biol Chem 1998; 273(5)3027–3032
  • Cabiscol E, Piulats E, Echave P, Herrero E, Ros J. Oxidative stress promotes specific protein damage in Saccharomyces cerevisiae. J Biol Chem 2000; 275(35)27393–27398
  • Godon C, Lagniel G, Lee J, Buhler JM, Kieffer S, Perrot M, Boucherie H, Toledano MB, Labarre J. The H2O2 stimulon in Saccharomyces cerevisiae. J Biol Chem 1998; 273(35)22480–22489
  • Reverter-Branchat G, Cabiscol E, Tamarit J, Ros J. Oxidative damage to specific proteins in replicative and chronological-aged Saccharomyces cerevisiae: Common targets and prevention by calorie restriction. J Biol Chem 2004; 279(30)31983–31989
  • Rabek JP, Boylston WH, Papaconstantinou J. Carbonylation of ER chaperone proteins in aged mouse liver. Biochem Biophys Res Commun 2003; 305(3)566–572
  • Reddy RK, Mao C, Baumeister P, Austin RC, Kaufman RJ, Lee AS. Endoplasmic reticulum chaperone protein GRP78 protects cells from apoptosis induced by topoisomerase inhibitors: Role of ATP binding site in suppression of caspase-7 activation. J Biol Chem 2003; 278(23)20915–20924
  • Nutt L, Chandra J, Pataer A, Fang B, Roth J, Swisher S, O'Neill R, McConkey D. Bax mediated Ca2+ mobilization promotes cytochrome C release during apoptosis. J Biol Chem 2002; 277: 20301–20308
  • Nutt L, Pataer A, Pahler J, Fang B, Roth J, McConkey D, Swisher S. Bax and Bak promote apoptosis by modulating endoplasmic reticular and mitochondrial Ca2+ stores. J Biol Chem 2002; 277: 9219–9225
  • Ma YJ, Hendershot LM. The role of the unfolded protein response in tumour development: Friend or foe?. Nat Rev Cancer 2004; 4(12)966–977

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.