339
Views
14
CrossRef citations to date
0
Altmetric
Original

Formation of TEMPOL-hydroxylamine during reaction between TEMPOL and hydroxyl radical: HPLC/ECD study

, , , , , & show all
Pages 505-512 | Received 21 Feb 2008, Published online: 07 Jul 2009

References

  • Utsumi H, Yasukawa K, Soeda T, Yamada K, Shigemi R, Yao T, Tsuneyoshi M. Noninvasive mapping of reactive oxygen species by in vivo electron spin resonance spectroscopy in indomethacin-induced gastric ulcers in rats. J Pharmacol Exp Ther 2006; 317: 228–235
  • Kato N, Yanaka K, Hyodo K, Homma K, Nagase S, Nose T. Stable nitroxide Tempol ameliorates brain injury by inhibiting lipid peroxidation in a rat model of transient focal cerebral ischemia. Brain Res 2003; 979: 188–193
  • Yamato M, Egashira T, Utsumi H. Application of in vivo ESR spectroscopy to measurement of cerebrovascular ROS generation in stroke. Free Radic Biol Med 2003; 35: 1619–1631
  • Liang Q, Smith AD, Pan S, Tyurin VA, Kagan VE, Hastings TG, Schor NF. Neuroprotective effects of TEMPOL in central and peripheral nervous system models of Parkinson's disease. Biochem Pharmacol 2005; 70: 1371–1381
  • Kasazaki K, Yasukawa K, Sano H, Utsumi H. Non-invasive analysis of reactive oxygen species generated in NH4OH-induced gastric lesions of rats using a 300 MHz in vivo ESR technique. Free Radic Res 2003; 37: 757–766
  • Hermida-Ameijeiras A, Mendez-Alvarez E, Sanchez-Iglesias S, Sanmartin-Suarez C, Soto-Otero R. Autoxidation and MAO-mediated metabolism of dopamine as a potential cause of oxidative stress: role of ferrous and ferric ions. Neurochem Int 2004; 45: 103–116
  • Madden KP, Taniguchi H. In situ radiolysis time-resolved ESR studies of spin trapping by DMPO: reevaluation of hydroxyl radical and hydrated electron trapping rates and spin adduct yields. J Phys Chem 1996; 100: 7511–7516
  • Shimizu M. Strong interaction between the ring system and the ionosphere of Saturn. Moon and the Planets 1980; 22: 521–522
  • Saito K, Takeshita K, Ueda J, Ozawa T. Two reaction sites of a spin label, TEMPOL (4-hydroxy-2,2,6,6-tetramethylpiperidine-N-oxyl), with hydroxyl radical. J Pharm Sci 2003; 92: 275–280
  • Deffner U, Schimmack W. Letter: Radiation effects on aqueous solutions of the nitroxyl free radical TMPN (2,2,6,6-tetramethyl-4-piperidinol-N-oxyl). Int J Radiat Biol Relat Stud Phys Chem Med 1976; 29: 71–75
  • Willson RL. Reaction of triacetoneamine-N-oxyl with hydroxyl radicals. Int J Radiat Biol Relat Stud Phys Chem Med 1972; 21: 401–403
  • Takeshita K, Saito K, Ueda J, Anzai K, Ozawa T. Kinetic study on ESR signal decay of nitroxyl radicals, potent redox probes for in vivo ESR spectroscopy, caused by reactive oxygen species. Biochim Biophys Acta 2002; 1573: 156–164
  • Krishna MC, Grahame DA, Samuni A, Mitchell JB, Russo A. Oxoammonium cation intermediate in the nitroxide-catalyzed dismutation of superoxide. Proc Natl Acad Sci USA 1992; 89: 5537–5541
  • Zhdanov RI, Komarov PG. Sterically-hindered hydroxylamines as bioactive spin labels. Free Radic Res Commun 1990; 9: 367–377
  • Bobko AA, Kirilyuk IA, Grigor'ev IA, Zweier JL, Khramtsov VV. Reversible reduction of nitroxides to hydroxylamines: roles for ascorbate and glutathione. Free Radic Biol Med 2007; 42: 404–412
  • Mcilvaine TC. A buffer solution for colorimetric comparison. J Biol Chem 1921; 49: 183–186
  • Asmus KD, Nigam S. Kinetics of nitroxyl radical reactions. A pulse-radiolysis conductivity study. Int J Radiat Biol Relat Stud Phys Chem Med 1976; 29: 211–219
  • Nigam S, Asmus KD, Willson RL. Electron transfer and addition reactions of free nitroxyl radicals with radiation induced radicals. J Chem Soc Faraday Trans 1976; 72: 2324–2340

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.