Sodium deoxycholate causes nitric oxide mediated DNA damage in oesophageal cells

References

• Vakil N, van Zanten SV, Kahrilas P, Dent J, Jones R. The Montreal definition and classification of gastroesophageal reflux disease: a global evidence-based consensus. CME. Am J Gastroenterol 2006; 101: 1900–1920
   PubMed Web of Science ®Google Scholar
• Salvatore S, Vandenplas Y. Gastro-oesophageal reflux disease and motility disorders. Best Practice Res Clin Gastroenterol 2003; 17: 163–179
   Google Scholar
• Dent J, El-Serag HB, Wallander MA, Johansson S. Epidemiology of gastro-oesophageal reflux disease: a systematic review. Gut 2005; 54: 710–717
   PubMed Web of Science ®Google Scholar
• Talwar V, de Caestecker J. Hiatus hernia and gastro-oesophageal reflux disease. Medicine 2007; 35: 194–198
   Google Scholar
• Meining A, Classen M. The role of diet and lifestyle measures in the pathogenesis and treatment of gastroesophageal reflux disease. Am J Gastroenterol 2000; 95: 2692–2697
   PubMed Web of Science ®Google Scholar
• Trudgill NJ, Kapur KC, Riley SA. Familial clustering of reflux symptoms. Am J Gastroenterol 1999; 94: 1172–1178
   PubMedGoogle Scholar
• Cameron AJ, Lagergren J, Henriksson C, Nyren O, Locke GR, III, Pedersen NL. Gastroesophageal reflux disease in monozygotic and dizygotic twins. Gastroenterology 2002; 122: 55–59
   PubMed Web of Science ®Google Scholar
• Lagergren J, Bergstrom R, Lindgren A, Nyren O. Symptomatic gastroesophageal reflux as a risk factor for esophageal adenocarcinoma [see comments]. N Engl J Med 1999; 340: 825–831
   PubMed Web of Science ®Google Scholar
• Oberg S, Demeester TR, Peters JH, Hagen JA, Nigro JJ, Demeester SR, Theisen J, Campos GM, Crookes PF. The extent of barrett's esophagus depends on the status of the lower esophageal sphincter and the degree of esophageal acid exposure. J Thorac Cardiovasc Surg 1999; 117: 572–580
   PubMed Web of Science ®Google Scholar
• Nehra D, Howell P, Williams CP, Pye JK, Beynon J. Toxic bile acids in gastro-oesophageal reflux disease: influence of gastric acidity. Gut 1999; 44: 598–602
   PubMed Web of Science ®Google Scholar
• Jimenez P, Piazuelo E, Sanchez MT, Ortego J, Soteras F, Lanas A. Free radicals and antioxidant systems in reflux esophagitis and Barrett's esophagus. W J Gastroenterol 2005; 11: 2697–2703
   PubMedGoogle Scholar
• Wetscher GJ, Hinder RA, Klingler P, Gadenstatter M, Perdikis G, Hinder PR. Reflux esophagitis in humans is a free radical event. Dis Esophagus 1997; 10: 29–32
   PubMedGoogle Scholar
• Vaninetti NM, Geldenhuys L, Porter GA, Risch H, Hainaut P, Guernsey DL, Casson AG. Inducible nitric oxide synthase, nitrotyrosine and p53 mutations in the molecular pathogenesis of Barrett's esophagus and esophageal adenocarcinoma. Molec Carcinogen 2007; 44: 275–285
   Google Scholar
• Ostrowski J, Mikula M, Karczmarski J, Rubel T, Wyrwicz LS, Bragoszewski P, Gaj P, Dadlez M, Butruk E, Regula J. Molecular defense mechanisms of Barrett's metaplasia estimated by an integrative genomics. J Molec Med 2007; 85: 733–743
   PubMed Web of Science ®Google Scholar
• Hirsch DP, Holloway RH, Tytgat GNJ, Boeckxstaens GEE. Involvement of nitric oxide in human transient lower esophageal sphincter relaxations and esophageal primary peristalsis. Gastroenterology 1998; 115: 1374–1380
   PubMed Web of Science ®Google Scholar
• Park SW, Lee SG, Song SH, Heo DS, Park BJ, Lee DW, Kim KH, Sung MW. The effect of nitric oxide on cyclooxygenase-2 (COX-2) overexpression in head and neck cancer cell lines. Int J Cancer 2003; 107: 729–738
   PubMed Web of Science ®Google Scholar
• Rao CV. Nitric oxide signaling in colon cancer chemoprevention. [Review] [114 refs]. Mutat Res 2004; 555: 107–119
   PubMed Web of Science ®Google Scholar
• Sawa T, Ohshima H. Nitrative DNA damage in inflammation and its possible role in carcinogenesis. Nitric Oxide 2006; 14: 91–100
   PubMed Web of Science ®Google Scholar
• Jolly AJ, Wild CP, Hardie LJ. Acid and bile salts induce DNA damage in human oesophageal cell lines. Mutagenesis 2004; 19: 319–324
   PubMedGoogle Scholar
• Grisham MB, Johnson GG, Lancaster JR. Quantitation of nitrate and nitrite in extracellular fluids. In: Lester P. Methods in enzymology nitric oxide part A: Sources and detection of NO; NO synthase. Volume 268. Academic Press: OrlandoUSA. 1996 237–246.
   Google Scholar
• Guevara I, Iwanejko J, Mbiska-Kie A, Pankiewicz J, Wanat A, Anna P, Golbek I, Bartu S, Malczewska-Malec M, Szczudlik A. Determination of nitrite/nitrate in human biological material by the simple Griess reaction. Clin Chim Acta 1998; 274: 177–188
   PubMed Web of Science ®Google Scholar
• Kojima H, Sakurai K, Kikuchi K, Kawahara S, Kirino Y, Nagoshi H, Hirata Y, Nagano T. Development of a fluorescent indicator for nitric oxide based on the fluorescein chromophore. Chem Pharm Bull 1998; 46: 373–375
   PubMed Web of Science ®Google Scholar
• Leikert JF, Rathel TR, Muller C, Vollmar AM, Dirsch VM. Reliable in vitro measurement of nitric oxide released from endothelial cells using low concentrations of the fluorescent probe 4,5-diaminofluorescein. FEBS Lett 2001; 506: 131–134
   PubMed Web of Science ®Google Scholar
• Tice RR, Agurell E, Anderson D, Burlinson B, Hartmann A, Kobayashi H, Miyamae Y, Rojas E, Ryu JC, Sasaki YF. Single cell gel/comet assay: guidelines for in vitro and in vivo genetic toxicology testing. Environ Molec Mutagen 2000; 35: 206–221
   PubMed Web of Science ®Google Scholar
• Stoner GD, Kaighn ME, Reddel RR, Resau JH, Bowman D, Naito Z, Matsukura N, You M, Galati AJ, Harris CC. Establishment and characterization of SV40 T-antigen immortalized human esophageal epithelial cells. Cancer Res 1991; 51: 365–371
   PubMedGoogle Scholar
• Araki Y, Katoh T, Ogawa A, Bamba S, Andoh A, Koyama S, Fujiyama Y, Bamba T. Bile acid modulates transepithelial permeability via the generation of reactive oxygen species in the Caco-2 cell line. Free Radic Biol Med 2005; 39: 769–780
   Google Scholar
• Dvorak K, Payne CM, Chavarria M, Ramsey L, Dvorakova B, Bernstein H, Holubec H, Sampliner RE, Guy N, Condon A, Bernstein C, Green SB, Prasad A, Garewal HS. Bile acids in combination with low pH induce oxidative stress and oxidative DNA damage: relevance to the pathogenesis of Barrett's oesophagus. Gut 2007; 56: 763–771
   PubMed Web of Science ®Google Scholar
• Jenkins GJ, Harries K, Doak SH, Wilmes A, Griffiths AP, Baxter JN, Parry JM. The bile acid deoxycholic acid (DCA) at neutral pH activates NF-kappaB and induces IL-8 expression in oesophageal cells in vitro. Carcinogenesis 2004; 25: 317–323
   PubMed Web of Science ®Google Scholar
• Jenkins GJS, D'Souza FR, Suzen SH, Eltahir ZS, James SA, Parry JM, Griffiths PA, Baxter JN. Deoxycholic acid at neutral and acid pH, is genotoxic to oesophageal cells through the induction of ROS: the potential role of anti-oxidants in Barrett's oesophagus. Carcinogenesis 2007; 28: 136–142
   PubMed Web of Science ®Google Scholar
• Oh TY, Lee JS, Ahn BO, Cho H, Kim WB, Kim YB, Surh YJ, Cho SW, Lee KM, Hahm KB. Oxidative stress is more important than acid in the pathogenesis of reflux oesophagitis in rats. Gut 2001; 49: 364–371
   PubMed Web of Science ®Google Scholar
• O'Riordan JM, Bdel-Latif MM, Ravi N, McNamara D, Byrne PJ, McDonald GS, Keeling PW, Kelleher D, Reynolds JV. Proinflammatory cytokine and nuclear factor kappa-B expression along the inflammation-metaplasia-dysplasia-adenocarcinoma sequence in the esophagus. Am J Gastroenterol 2005; 100: 1257–1264
   PubMed Web of Science ®Google Scholar
• Zhen J, Lu H, Wang XQ, Vaziri ND, Zhou XJ. Upregulation of endothelial and inducible nitric oxide synthase expression by reactive oxygen species. Am J Hypertension 2008; 21: 28–34
   Google Scholar
• Chien YH, Bau DT, Jan KY. Nitric oxide inhibits DNA-adduct excision in nucleotide excision repair. Free Radic Biol Med 2004; 36: 1011–1017
   PubMed Web of Science ®Google Scholar
• Burney S, Caulfield JL, Niles JC, Wishnok JS, Tannenbaum SR. The chemistry of DNA damage from nitric oxide and peroxynitrite. Mutat Res/Fundam Molec Mech Mutagen 1999; 424: 37–49
   PubMed Web of Science ®Google Scholar
• Sandoval-Chacon M, Thompson JH, Zhang XJ, Liu X, Mannick EE, Sadowska-Krowicka H, Charbonnet RM, Clark DA, Miller MJ. Antiinflammatory actions of cat's claw: the role of NF-kappaB. Aliment Pharmacol Therapeut 1998; 12: 1279–1289
   Google Scholar
• Casellas F, Mourelle M, Papo M, Guarner F, Antolin M, Armengol JR, Malagelada JR. Bile acid induced colonic irritation stimulates intracolonic nitric oxide release in humans. Gut 1996; 38: 719–723
   PubMed Web of Science ®Google Scholar
• Gumpricht E, Dahl R, Yerushalmi B, Devereaux MW, Sokol RJ. Nitric oxide ameliorates hydrophobic bile acid-induced apoptosis in isolated rat hepatocytes by non-mitochondrial pathways. J Biol Chem 2002; 2777: 25823–25830
   Google Scholar
• Nakajima T, Okuda Y, Chisaki K, Shin WS, Iwasawa K, Morita T, Matsumoto A, Suzuki JI, Suzuki S, Yamada N, Toyo-Oka T, Nagai R, Omata M. Bile acids increase intracellular Ca(2+) concentration and nitric oxide production in vascular endothelial cells. Br J Pharmacol 2000; 130: 1457–1467
   Google Scholar
• Crowley-Weber CL, Payne CM, Gleason-Guzman M, Watts GS, Futscher B, Waltmire CN, Crowley C, Dvorakova K, Bernstein C, Craven M, Garewal H, Bernstein H. Development and molecular characterization of HCT-116 cell lines resistant to the tumor promoter and multiple stress-inducer, deoxycholate. Carcinogenesis 2002; 23: 2063–2080
   PubMed Web of Science ®Google Scholar
• Dall‘Agnol M, Bernstein C, Bernstein H, Garewal H, Payne CM. Identification of S-nitrosylated proteins after chronic exposure of colon epithelial cells to deoxycholate. Proteomics 2006; 6: 1654–1662
   Google Scholar
• Bdel-Latif MM, O'Riordan JM, Ravi N, Kelleher D, Reynolds JV. Activated nuclear factor-kappa B and cytokine profiles in the esophagus parallel tumor regression following neoadjuvant chemoradiotherapy. Dis Esophagus 2005; 18: 246–252
   Google Scholar
• Chen T, Hwang H, Rose ME, Nines RG, Stoner GD. Chemopreventive properties of black raspberries in N-nitrosomethylbenzylamine-induced rat esophageal tumorigenesis: down-regulation of cyclooxygenase-2, inducible nitric oxide synthase, and c-Jun. Cancer Res 2006; 66: 2853–2859
   PubMed Web of Science ®Google Scholar
• Iijima K, Henry E, Moriya A, Wirz A, Kelman AW, McColl KEL. Dietary nitrate generates potentially mutagenic concentrations of nitric oxide at the gastroesophageal junction. Gastroenterology 2002; 122: 1248–1257
   PubMed Web of Science ®Google Scholar
• Gago B, Lundberg JO, Barbosa RM, Laranjinha J. Red wine-dependent reduction of nitrite to nitric oxide in the stomach. Free Radic Biol Med 2007; 43: 1233–1242
   PubMed Web of Science ®Google Scholar