Is serum gamma-glutamyltransferase a marker of exposure to various environmental pollutants?

References

• Strasak AM, Rapp K, Brant LJ, Hilbe W, Gregory M, Oberaigner W, Ruttmann E, Concin H, Diem G, Pfeiffer KP, Ulmer H. Association of gamma-glutamyltransferase and risk of cancer incidence in men: a prospective study. Cancer Res 2008; 68: 3970–3977
   PubMed Web of Science ®Google Scholar
• Lee DH, Silventoinen K, Hu G, Jacobs DR, Jr, Jousilahti P, Sundvall J, Tuomilehto J. Serum gamma-glutamyltransferase predicts non-fatal myocardial infarction and fatal coronary heart disease among 28,838 middle-aged men and women. Eur Heart J 2006; 27: 2170–2176
   PubMed Web of Science ®Google Scholar
• Lee DH, Jacobs DR, Jr, Gross M, Kiefe CI, Roseman J, Lewis CE, Steffes M. Gamma-glutamyltransferase is a predictor of incident diabetes and hypertension: the Coronary Artery Risk Development in Young Adults (CARDIA) study. Clin Chem 2003; 49: 1358–1366
   PubMed Web of Science ®Google Scholar
• Teschke R, Brand A, Strohmeyer G. Induction of hepatic microsomal gamma-glutamyltransferase activity following chronic alcohol consumption. Biochem Biophys Res Commun 1977; 75: 718–724
   PubMed Web of Science ®Google Scholar
• Goldberg DM, Martin JV. Role of gamma-glutamyl transpeptidase activity in the diagnosis of hepatobiliary disease. Digestion 1975; 12: 232–246
   PubMed Web of Science ®Google Scholar
• Lee DH, Blomhoff R, Jacobs DR, Jr. Is serum gamma glutamyltransferase a marker of oxidative stress?. Free Radic Res 2004; 38: 535–539
   PubMed Web of Science ®Google Scholar
• Whitfield JB. Gamma glutamyl transferase. Crit Rev Clin Lab Sci 2001; 38: 263–355
   PubMed Web of Science ®Google Scholar
• Hanigan MH, Frierson HF, Jr. Immunohistochemical detection of gamma-glutamyl transpeptidase in normal human tissue. J Histochem Cytochem 1996; 44: 1101–1108
   PubMed Web of Science ®Google Scholar
• Franco R, Schoneveld OJ, Pappa A, Panayiotidis MI. The central role of glutathione in the pathophysiology of human diseases. Arch Physiol Biochem 2007; 113: 234–258
   PubMedGoogle Scholar
• Droge W. Free radicals in the physiological control of cell function. Physiol Rev 2002; 82: 47–95
   PubMed Web of Science ®Google Scholar
• Emdin M, Pompella A, Paolicchi A. Gamma-glutamyltransferase, atherosclerosis, and cardiovascular disease: triggering oxidative stress within the plaque. Circulation 2005; 112: 2078–2080
   PubMed Web of Science ®Google Scholar
• Stark AA, Russell JJ, Langenbach R, Pagano DA, Zeiger E, Huberman E. Localization of oxidative damage by a glutathione-gamma-glutamyl transpeptidase system in preneoplastic lesions in sections of livers from carcinogen-treated rats. Carcinogenesis 1994; 15: 343–348
   PubMed Web of Science ®Google Scholar
• Paolicchi A, Emdin M, Ghliozeni E, Ciancia E, Passino C, Popoff G, Pompella A. Images in cardiovascular medicine. Human atherosclerotic plaques contain gamma-glutamyl transpeptidase enzyme activity. Circulation 2004; 109: 1440
   PubMed Web of Science ®Google Scholar
• Paolicchi A, Minotti G, Tonarelli P, Tongiani R, De Cesare D, Mezzetti A, Dominici S, Comporti M, Pompella A. Gamma-glutamyl transpeptidase-dependent iron reduction and LDL oxidation—a potential mechanism in atherosclerosis. J Investig Med 1999; 47: 151–160
   PubMed Web of Science ®Google Scholar
• Zalit I, Glass GA, Stark AA. The role of chelators in the catalysis of glutathione-gamma-glutamyl transpeptidase-dependent lipid peroxidation by transition metals. Biochem Mol Biol Int 1996; 40: 1123–1133
   PubMedGoogle Scholar
• Carr A, Frei B. Does vitamin C act as a pro-oxidant under physiological conditions?. Faseb J 1999; 13: 1007–1024
   PubMed Web of Science ®Google Scholar
• Lee DH, Lim JS, Song K, Boo Y, Jacobs DR, Jr. Graded associations of blood lead and urinary cadmium concentrations with oxidative-stress-related markers in the U.S. population: results from the third National Health and Nutrition Examination Survey. Environ Health Perspect 2006; 114: 350–354
   PubMed Web of Science ®Google Scholar
• Lee DH, Jacobs DR, Jr. Association between serum concentrations of persistent organic pollutants and gamma glutamyltransferase: results from the National Health and Examination Survey 1999–2002. Clin Chem 2006; 52: 1825–1827
   PubMed Web of Science ®Google Scholar
• Ishiguro M, Suzuki M, Takio K, Matsuzawa T, Titani K. Complete amino acid sequence of rat liver cytosolic alanine aminotransferase. Biochemistry 1991; 30: 6048–6053
   Google Scholar
• Xu C, Li CY, Kong AN. Induction of phase I, II and III drug metabolism/transport by xenobiotics. Arch Pharm Res 2005; 28: 249–268
   PubMed Web of Science ®Google Scholar
• Coles B, Ketterer B. The role of glutathione and glutathione transferases in chemical carcinogenesis. Crit Rev Biochem Mol Biol 1990; 25: 47–70
   PubMed Web of Science ®Google Scholar
• Ballatori N. Glutathione mercaptides as transport forms of metals. Adv Pharmacol 1994; 27: 271–298
   PubMedGoogle Scholar
• Hinchman CA, Ballatori N. Glutathione conjugation and conversion to mercapturic acids can occur as an intrahepatic process. J Toxicol Environ Health 1994; 41: 387–409
   PubMed Web of Science ®Google Scholar
• Wang W, Ballatori N. Endogenous glutathione conjugates: occurrence and biological functions. Pharmacol Rev 1998; 50: 335–356
   PubMed Web of Science ®Google Scholar
• Lee DH, Ha MH, Kam S, Chun B, Lee J, Song K, Boo Y, Steffen L, Jacobs DR, Jr. A strong secular trend in serum gamma-glutamyltransferase from 1996 to 2003 among South Korean men. Am J Epidemiol 2006; 163: 57–65
   PubMed Web of Science ®Google Scholar
• Lee DH, Ha MH, Christiani DC. Body weight, alcohol consumption and liver enzyme activity–a 4-year follow-up study. Int J Epidemiol 2001; 30: 766–770
   PubMedGoogle Scholar
• Vincent HK, Taylor AG. Biomarkers and potential mechanisms of obesity-induced oxidant stress in humans. Int J Obes (Lond) 2006; 30: 400–418
   PubMed Web of Science ®Google Scholar
• Schrader M, Fahimi HD. Peroxisomes and oxidative stress. Biochim Biophys Acta 2006; 1763: 1755–1766
   PubMed Web of Science ®Google Scholar
• Cusack BJ. Pharmacokinetics in older persons. Am J Geriatr Pharmacother 2004; 2: 274–302
   PubMedGoogle Scholar
• Whitfield JB, Zhu G, Nestler JE, Heath AC, Martin NG. Genetic covariation between serum gamma-glutamyltransferase activity and cardiovascular risk factors. Clin Chem 2002; 48: 1426–1431
   Google Scholar
• Dorne JL, Walton K, Renwick AG. Human variability in xenobiotic metabolism and pathway-related uncertainty factors for chemical risk assessment: a review. Food Chem Toxicol 2005; 43: 203–216
   PubMed Web of Science ®Google Scholar
• Myren M, Mose T, Mathiesen L, Knudsen LE. The human placenta—an alternative for studying foetal exposure. Toxicol In Vitro 2007; 21: 1332–1040
   PubMed Web of Science ®Google Scholar
• Szyf M. The dynamic epigenome and its implications in toxicology. Toxicol Sci 2007; 100: 7–23
   PubMed Web of Science ®Google Scholar
• Kortenkamp A. Ten years of mixing cocktails: a review of combination effects of endocrine-disrupting chemicals. Environ Health Perspect 2007; 115(Suppl 1)98–105
   PubMedGoogle Scholar
• Lee DH, Steffes MW, Jacobs DR, Jr. Can persistent organic pollutants explain the association between serum gamma-glutamyltransferase and type 2 diabetes?. Diabetologia 2008; 51: 402–407
   PubMed Web of Science ®Google Scholar
• Lee DH, Steffes M, Jacobs DR. Positive associations of serum concentration of polychlorinated biphenyls or organochlorine pesticides with self-reported arthritis, especially rheumatoid type, in women. Environ Health Perspect 2007; 115: 883–888
   PubMed Web of Science ®Google Scholar
• Lee DH, Lee IK, Porta M, Steffes M, Jacobs DR, Jr. Relationship between serum concentrations of persistent organic pollutants and the prevalence of metabolic syndrome among non-diabetic adults: results from the National Health and Nutrition Examination Survey 1999–2002. Diabetologia. 2007; 50: 1841–1851
   PubMed Web of Science ®Google Scholar
• Lee DH, Jacobs DR, Porta M. Association of serum concentrations of persistent organic pollutants with the prevalence of learning disability and attention deficit disorder. J Epidemiol Community Health 2007; 61: 591–596
   Google Scholar
• Ha MH, Lee DH, Jacobs DR. Association between serum concentrations of persistent organic pollutants and self-reported cardiovascular disease prevalence: results from the National Health and Nutrition Examination Survey, 1999–2002. Environ Health Perspect 2007; 115: 1204–1209
   PubMed Web of Science ®Google Scholar
• Lee DH, Lee IK, Song K, Steffes M, Toscano W, Baker BA, Jacobs DR, Jr. A strong dose-response relation between serum concentrations of persistent organic pollutants and diabetes: results from the National Health and Examination Survey 1999–2002. Diabetes Care 2006; 29: 1638–1644
   PubMed Web of Science ®Google Scholar
• Higuchi Y. Glutathione depletion-induced chromosomal DNA fragmentation associated with apoptosis and necrosis. J Cell Mol Med 2004; 8: 455–464
   PubMed Web of Science ®Google Scholar
• Wu G, Fang YZ, Yang S, Lupton JR, Turner ND. Glutathione metabolism and its implications for health. J Nutr 2004; 134: 489–492
   PubMed Web of Science ®Google Scholar
• Jones DP, Brown LA, Sternberg P. Variability in glutathione-dependent detoxication in vivo and its relevance to detoxication of chemical mixtures. Toxicology 1995; 105: 267–274
   PubMed Web of Science ®Google Scholar