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Original Article

Carbon monoxide promotes gastric wound healing in mice via the protein kinase C pathway

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Pages 1098-1105 | Received 06 Apr 2016, Accepted 09 May 2016, Published online: 02 Jun 2016

References

  • Naito Y, Takagi T, Higashimura Y. Heme oxygenase-1 and anti-inflammatory M2 macrophages. Arch Biochem Biophys 2014;564:83–88.
  • Andreadou I, Iliodromitis EK, Rassaf T, Schulz R, Papapetropoulos A, Ferdinandy P. The role of gasotransmitters NO, H2S and CO in myocardial ischaemia/reperfusion injury and cardioprotection by preconditioning, postconditioning and remote conditioning. Br J Pharmacol 2015;172:1587–1606.
  • Takagi T, Uchiyama K, Naito Y. The therapeutic potential of carbon monoxide for inflammatory bowel disease. Digestion 2015;91:13–18.
  • Chang M, Xue J, Sharma V, Habtezion A. Protective role of hemeoxygenase-1 in gastrointestinal diseases. Cell Mol Life Sci 2015;72:1161–1173.
  • Hegazi RA, Rao KN, Mayle A, Sepulveda AR, Otterbein LE, Plevy SE. Carbon monoxide ameliorates chronic murine colitis through a heme oxygenase 1-dependent pathway. J Exp Med 2005;202:1703–1713.
  • Sheikh SZ, Hegazi RA, Kobayashi T, Onyiah JC, Russo SM, Matsuoka K, et al. An anti-inflammatory role for carbon monoxide and heme oxygenase-1 in chronic Th2-mediated murine colitis. J Immunol 2011;186:5506–5513.
  • Takagi T, Naito Y, Mizushima K, Akagiri S, Suzuki T, Hirata I, et al. Inhalation of carbon monoxide ameliorates TNBS-induced colitis in mice through the inhibition of TNF-α expression. Dig Dis Sci 2010;55:2797–2804.
  • Okabe S, Amagase K. An overview of acetic acid ulcer models-the history and state of the art of peptic ulcer research. Biol Pharm Bull 2005;28:1321–1341.
  • Okabe S, Roth JL, Pfeiffer CJ. A method for experimental, penetrating gastric and duodenal ulcers in rats. Observations on normal healing. Am J Dig Dis 1971;16:277–284.
  • Nakao A, Schmidt J, Harada T, Tsung A, Stoffels B, Cruz RJ, et al. A single intraperitoneal dose of carbon monoxide-saturated ringer's lactate solution ameliorates postoperative ileus in mice. J Pharmacol Exp Ther 2006;319:1265–1275.
  • Kohmoto J, Nakao A, Sugimoto R, Wang Y, Zhan J, Ueda H, et al. Carbon monoxide-saturated preservation solution protects lung grafts from ischemia-reperfusion injury. J Thorac Cardiovasc Surg 2008;136:1067–1075.
  • Nakao A, Huang CS, Stolz DB, Wang Y, Franks JM, Tochigi N, et al. Ex vivo carbon monoxide delivery inhibits intimal hyperplasia in arterialized vein grafts. Cardiovasc Res 2011;89:457–463.
  • Nakao A, Toyokawa H, Tsung A, Nalesnik MA, Stolz DB, Kohmoto J, et al. Ex vivo application of carbon monoxide in University of Wisconsin solution to prevent intestinal cold ischemia/reperfusion injury. Am J Transplant 2006;6:2243–2255.
  • Whitehead RH, VanEeden PE, Noble MD, Ataliotis P, Jat PS. Establishment of conditionally immortalized epithelial cell lines from both colon and small intestine of adult H-2Kb-tsA58 transgenic mice. Proc Natl Acad Sci USA 1993;90:587–591.
  • Yan F, Cao H, Chaturvedi R, Krishna U, Hobbs SS, Dempsey PJ, et al. Epidermal growth factor receptor activation protects gastric epithelial cells from helicobacter pylori-induced apoptosis. Gastroenterology 2009;136:1297–1307.
  • Petit V, Boyer B, Lentz D, Turner CE, Thiery JP, Valles AM. Phosphorylation of tyrosine residues 31 and 118 on paxillin regulates cell migration through an association with CRK in NBT-II cells. J Cell Biol 2000;148:957–970.
  • Suzuki H, Masaoka T, Minegidhi Y, Motosugi Y, Miura S, Ishii H. Lansoprazole promotes gastric mucosal cell proliferation and migration by activating p44/p42 mitogen-activated protein kinase. Wound Repair Regen 2004;12:93–99.
  • Takagi T, Naito Y, Uchiyama K, Okuda T, Mizushima K, Suzuki T, et al. Rebamipide promotes healing of colonic ulceration through enhanced epithelial restitution. World J Gastroenterol 2011;17:3802–3809.
  • Uchiyama K, Naito Y, Takagi T, Mizushima K, Hayashi N, Harusato A, et al. Carbon monoxide enhance colonic epithelial restitution via FGF15 derived from colonic myofibroblasts. Biochem Biophys Res Commun 2010;391:1122–1126.
  • Uc A, Zhu X, Wagner BA, Buettner GR, Berg DJ. Heme oxygenase-1 is protective against nonsteroidal anti-inflammatory drug-induced gastric ulcers. J Pediatr Gastroenterol Nutr 2012;54:471–476.
  • Ueda K, Ueyama T, Yoshida K, Kimura H, Ito T, Shimizu Y, et al. Adaptive HNE-Nrf2-HO-1 pathway against oxidative stress is associated with acute gastric mucosal lesions. Am J Physiol Gastrointest Liver Physiol 2008;295:G460–G469.
  • Shibuya A, Onda K, Kawahara H, Uchiyama Y, Nakayama H, Omi T, et al. Sofalcone, a gastric mucosa protective agent, increases vascular endothelial growth factor via the Nrf2-heme-oxygenase-1 dependent pathway in gastric epithelial cells. Biochem Biophys Res Commun 2010;398:581–584.
  • Ueda K, Ueyama T, Oka M, Ito T, Tsuruo Y, Ichinose M. Polaprezinc (Zinc L-carnosine) is a potent inducer of anti-oxidative stress enzyme, heme oxygenase (HO)-1-a new mechanism of gastric mucosal protection. J Pharmacol Sci 2009;110:285–294.
  • Ibrahim MY, El-Sayed SA, Abdel-Hakim SM, Hassan MK, Aziz NM. The effect of induction of endogenous CO by heme-oxygenase inducer, hemin versus heme-oxygenase blocker, zinc mesoporphyrin on gastric secretion and ulceration under different conditions in adult male albino rats. Bratisl Lek Listy 2014;115:319–329.
  • Ibrahim I, El-Sayed S, Abdel-Hakim S, Hassan M, Aziz N. Inhibition of endogenous CO by ZnPP protects against stress-induced gastric lesion in adult male albino rats. J Physiol Biochem 2012;68:319–328.
  • Dieckgraefe BK, Weems DM, Santoro SA, Alpers DH. ERK and p38 MAP kinase pathways are mediators of intestinal epithelial wound-induced signal transduction. Biochem Biophys Res Commun 1997;233:389–394.
  • Yamaoka T, Frey MR, Dise RS, Bernard JK, Polk DB. Specific epidermal growth factor receptor autophosphorylation sites promote mouse colon epithelial cell chemotaxis and restitution. Am J Physiol Gastrointest Liver Physiol 2011;301:G368–G376.
  • Fujimoto H, Ohno M, Ayabe S, Kobayashi H, Ishizaka N, Kimura H, et al. Carbon monoxide protects against cardiac ischemia–reperfusion injury in vivo via MAPK and Akt–eNOS pathways. Arterioscler Thromb Vasc Biol 2004;24:1848–1853.
  • Kaizu T, Ikeda A, Nakao A, Tsung A, Toyokawa H, Ueki S, et al. Protection of transplant-induced hepatic ischemia/reperfusion injury with carbon monoxide via MEK/ERK1/2 pathway downregulation. Am J Physiol Gastrointest Liver Physiol 2008;294:G236–G244.
  • Otterbein LE, Bach FH, Alam J, Soares M, Lu HT, Wysk M, et al. Carbon monoxide has anti-inflammatory effects involving the mitogen-activated protein kinase pathway. Nat Med 2000;6:422–428.
  • Bani-Hani MG, Greenstein D, Mann BE, Green CJ, Motterlini R. A carbon monoxide-releasing molecule (CORM-3) attenuates lipopolysaccharide- and interferon-gamma-induced inflammation in microglia. Pharmacol Rep 2006;58:132–144.
  • Nishizuka Y. The molecular heterogeneity of protein kinase C and its implications for cellular regulation. Nature 1988;334:661–665.
  • Chandrasekher G, Bazan NG, Bazan HE. Selective changes in protein kinase C (PKC) isoform expression in rabbit corneal epithelium during wound healing. Inhibition of corneal epithelial repair by PKCalpha antisense. Exp Eye Res 1998;67:603–610.
  • Lin N, Bazan HE. Protein kinase C subspecies in rabbit corneal epithelium: increased activity of alpha subspecies during wound healing. Curr Eye Res 1992;11:899–907.
  • Sharma GD, Kakazu A, Bazan HE. Protein kinase C alpha and epsilon differentially modulate hepatocyte growth factor-induced epithelial proliferation and migration. Exp Eye Res 2007;85:289–297.

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