Advanced glycation end-products disrupt human endothelial cells redox homeostasis: new insights into reactive oxygen species production

References

• Orasanu G, Plutzky J. The pathologic continuum of diabetic vascular disease. J Am Coll Cardiol. 2009;53(5):S35–S42.
   PubMed Web of Science ®Google Scholar
• Singh R, Barden A, Mori T, et al. Advanced glycation end-products: a review. Diabetologia. 2001;44(2):129–146.
   PubMed Web of Science ®Google Scholar
• Verzijl N, Degroot J, Oldehinkel E, et al. Age-related accumulation of Maillard reaction products in human articular cartilage collagen. Biochem J. 2000;350(2):381–387.
   PubMedGoogle Scholar
• Haus JM, Carrithers JA, Trappe SW, et al. Collagen, cross-linking, and advanced glycation end products in aging human skeletal muscle. J Appl Physiol (1985). 2007;103(6):2068–2076.
   PubMed Web of Science ®Google Scholar
• Merlot AM, Kalinowski DS, Richardson DR. Unraveling the mysteries of serum albumin-more than just a serum protein. Front Physiol. 2014;5:299.
   PubMed Web of Science ®Google Scholar
• Singh VP, Bali A, Singh N, et al. Advanced glycation end products and diabetic complications. Korean J Physiol Pharmacol. 2014;18(1):1–14.
   PubMed Web of Science ®Google Scholar
• Stirban A, Gawlowski T, Roden M. Vascular effects of advanced glycation endproducts: clinical effects and molecular mechanisms. Mol Metab. 2014;3(2):94–108.
   PubMed Web of Science ®Google Scholar
• Madamanchi NR, Vendrov A, Runge MS. Oxidative stress and vascular disease. Arterioscler Thromb Vasc Biol. 2005;25(1):29–38.
   PubMed Web of Science ®Google Scholar
• Rodiño-Janeiro BK, González-Peteiro M, Ucieda-Somoza R, et al. Glycated albumin, a precursor of advanced glycation end-products, up-regulates NADPH oxidase and enhances oxidative stress in human endothelial cells: molecular correlate of diabetic vasculopathy. Diabetes Metab Res Rev. 2010;26(7):550–558.
   PubMed Web of Science ®Google Scholar
• Ishibashi Y, Matsui T, Maeda S, et al. Advanced glycation end products evoke endothelial cell damage by stimulating soluble dipeptidyl peptidase-4 production and its interaction with mannose 6-phosphate/insulin-like growth factor II receptor. Cardiovasc Diabetol. 2013;12(1):125.
   PubMed Web of Science ®Google Scholar
• Paradela-Dobarro B, Rodiño-Janeiro BK, Alonso J, et al. Key structural and functional differences between early and advanced glycation products. J Mol Endocrinol. 2016;56(1):23–37.
   PubMed Web of Science ®Google Scholar
• Basta G, Lazzerini G, Del Turco S, et al. At least 2 distinct pathways generating reactive oxygen species mediate vascular cell adhesion molecule-1 induction by advanced glycation end products. Arterioscler Thromb Vasc Biol. 2005;25(7):1401–1407.
   PubMed Web of Science ®Google Scholar
• Nam MH, Son WR, Lee YS, et al. Glycolaldehyde-derived advanced glycation end products (glycol-AGEs)-induced vascular smooth muscle cell dysfunction is regulated by the AGES-receptor (RAGE) axis in endothelium. Cell Commun Adhes. 2015;22(2–6):67–78.
   PubMed Web of Science ®Google Scholar
• Marimoutou M, Le Sage F, Smadja J, et al. Antioxidant polyphenol-rich extracts from the medicinal plants Antirhea borbonica, Doratoxylon apetalum and Gouania mauritiana protect 3T3-L1 preadipocytes against H2O2, TNFα and LPS inflammatory mediators by regulating the expression of superoxide dismutase and NF-κB genes. J Inflamm. 2015;12(1):10.
   Google Scholar
• Baraka-Vidot J, Guerin-Dubourg A, Bourdon E, et al. Impaired drug-binding capacities of in vitro and in vivo glycated albumin. Biochimie. 2012;94(9):1960–1967.
   PubMed Web of Science ®Google Scholar
• Baraka-Vidot J, Guerin-Dubourg A, Dubois F, et al. New insights into deleterious impacts of in vivo glycation on albumin antioxidant activities. Biochim Biophys Acta. 2013;1830(6):3532–3541.
   PubMed Web of Science ®Google Scholar
• Boyer F, Diotel N, Girard D, et al. Enhanced oxidative stress in adipose tissue from diabetic mice, possible contribution of glycated albumin. Biochem Biophys Res Commun. 2016;473(1):154–160.
   PubMed Web of Science ®Google Scholar
• Kojima H, Urano Y, Kikuchi K, et al. Fluorescent indicators for imaging nitric oxide production. Angew Chem Int Ed Engl. 1999;38(21):3209–3212.
   PubMed Web of Science ®Google Scholar
• Rhee SG, Chang TS, Jeong W, et al. Methods for detection and measurement of hydrogen peroxide inside and outside of cells. Mol Cells. 2010;29(6):539–549.
   PubMed Web of Science ®Google Scholar
• Oettl K, Stauber RE. Physiological and pathological changes in the redox state of human serum albumin critically influence its binding properties. Br J Pharmacol. 2007;151(5):580–590.
   PubMed Web of Science ®Google Scholar
• Patlevič P, Vašková J, Švorc P, et al. Reactive oxygen species and antioxidant defense in human gastrointestinal diseases. Integr Med Res. 2016;5(4):250–258.
   PubMed Web of Science ®Google Scholar
• Jung T, Höhn A, Grune T. The proteasome and the degradation of oxidized proteins: part II − protein oxidation and proteasomal degradation. Redox Biol. 2014;2:99–104.
   PubMed Web of Science ®Google Scholar
• Aruoma OI, Halliwell B, Hoey BM, et al. The antioxidant action of N-acetylcysteine: its reaction with hydrogen peroxide, hydroxyl radical, superoxide, and hypochlorous acid. Free Radic Biol Med. 1989;6(6):593–597.
   PubMed Web of Science ®Google Scholar
• Hatia S, Septembre-Malaterre A, Le Sage F, et al. Evaluation of antioxidant properties of major dietary polyphenols and their protective effect on 3T3-L1 preadipocytes and red blood cells exposed to oxidative stress. Free Radic Res. 2014;48(4):387–401.
   PubMed Web of Science ®Google Scholar
• Hsu CL, Huang SL, Yen GC. Inhibitory effect of phenolic acids on the proliferation of 3T3-L1 preadipocytes in relation to their antioxidant activity. J Agric Food Chem. 2006;54(12):4191–4197.
   PubMed Web of Science ®Google Scholar
• Yang JY, Della-Fera MA, Rayalam S, et al. Enhanced inhibition of adipogenesis and induction of apoptosis in 3T3-L1 adipocytes with combinations of resveratrol and quercetin. Life Sci. 2008;82(19–20):1032–1039.
   PubMed Web of Science ®Google Scholar
• Niwa T, Katsuzaki T, Ishizaki Y, et al. Imidazolone, a novel advanced glycation end product, is present at high levels in kidneys of rats with streptozotocin-induced diabetes. FEBS Lett. 1997;407(3):297–302.
   PubMed Web of Science ®Google Scholar
• Thornalley PJ. Protein and nucleotide damage by glyoxal and methylglyoxal in physiological systems – role in ageing and disease. Drug Metab Drug Interact. 2008;23(1–2):125–150.
   PubMedGoogle Scholar
• Rodiño-Janeiro BK, Paradela-Dobarro B, Raposeiras-Roubín S, et al. Glycated human serum albumin induces NF-κB activation and endothelial nitric oxide synthase uncoupling in human umbilical vein endothelial cells. J Diabetes Complications. 2015;29(8):984–992.
   PubMed Web of Science ®Google Scholar
• Amore A, Cirina P, Conti G, et al. Amadori-configurated albumin induces nitric oxide-dependent apoptosis of endothelial cells: a possible mechanism of diabetic vasculopathy. Nephrol Dial Transplant. 2004;19(1):53–60.
   PubMed Web of Science ®Google Scholar
• Liu Y, Ma Y, Wang R, et al. Advanced glycation end products accelerate ischemia/reperfusion injury through receptor of advanced end product/nitrative thioredoxin inactivation in cardiac microvascular endothelial cells. Antioxid Redox Signal. 2011;15(7):1769–1778.
   PubMed Web of Science ®Google Scholar
• Amore A, Cirina P, Mitola S, et al. Nonenzymatically glycated albumin (Amadori adducts) enhances nitric oxide synthase activity and gene expression in endothelial cells. Kidney Int. 1997;51(1):27–35.
   PubMed Web of Science ®Google Scholar
• Stamler JS, Jaraki O, Osborne J, et al. Nitric oxide circulates in mammalian plasma primarily as an S-nitroso adduct of serum albumin. Proc Natl Acad Sci USA. 1992;89(16):7674–7677.
   PubMed Web of Science ®Google Scholar
• Talmor Y, Golan E, Benchetrit S, et al. Calcitriol blunts the deleterious impact of advanced glycation end products on endothelial cells. Am J Physiol Renal Physiol. 2008;294(5):F1059–F1064.
   PubMed Web of Science ®Google Scholar
• Xu B, Ji Y, Yao K, et al. Inhibition of human endothelial cell nitric oxide synthesis by advanced glycation end-products but not glucose: relevance to diabetes. Clin Sci. 2005;109(5):439–446.
   PubMed Web of Science ®Google Scholar
• Brand MD. The sites and topology of mitochondrial superoxide production. Exp Gerontol. 2010;45(7–8):466–472.
   PubMed Web of Science ®Google Scholar
• Ren X, Ren L, Wei Q, et al. Advanced glycation end-products decreases expression of endothelial nitric oxide synthase through oxidative stress in human coronary artery endothelial cells. Cardiovasc Diabetol. 2017;16(1):52.
   PubMedGoogle Scholar
• Patche J, Girard D, Catan A, et al. Diabetes-induced hepatic oxidative stress: a new pathogenic role for glycated albumin. Free Radic Biol Med. 2017;102:133–148.
   PubMed Web of Science ®Google Scholar
• Weidinger A, Kozlov AV. Biological activities of reactive oxygen and nitrogen species: oxidative stress versus signal transduction. Biomolecules. 2015;5(2):472–484.
   PubMed Web of Science ®Google Scholar
• Grune T, Merker K, Sandig G, et al. Selective degradation of oxidatively modified protein substrates by the proteasome. Biochem Biophys Res Commun. 2003;305(3):709–718.
   PubMed Web of Science ®Google Scholar
• Friguet B. Oxidized protein degradation and repair in ageing and oxidative stress. FEBS Lett. 2006;580(12):2910–2916.
   PubMed Web of Science ®Google Scholar
• Cecarini V, Gee J, Fioretti E, et al. Protein oxidation and cellular homeostasis: emphasis on metabolism. Biochim Biophys Acta. 2007;1773(2):93–104.
   PubMed Web of Science ®Google Scholar
• Rajendran P, Rengarajan T, Thangavel J, et al. The vascular endothelium and human diseases. Int J Biol Sci. 2013;9(10):1057–1069.
   PubMed Web of Science ®Google Scholar
• Yan SD, Schmidt AM, Anderson GM, et al. Enhanced cellular oxidant stress by the interaction of advanced glycation end products with their receptors/binding proteins. J Biol Chem. 1994;269(13):9889–9897.
   PubMed Web of Science ®Google Scholar
• Wautier MP, Chappey O, Corda S, et al. Activation of NADPH oxidase by AGE links oxidant stress to altered gene expression via RAGE. Am J Physiol Endocrinol Metab. 2001;280(5):E685–E694.
   PubMed Web of Science ®Google Scholar
• Lander HM, Tauras JM, Ogiste JS, et al. Activation of the receptor for advanced glycation end products triggers a p21(ras)-dependent mitogen-activated protein kinase pathway regulated by oxidant stress. J Biol Chem. 1997;272(28):17810–17814.
   PubMed Web of Science ®Google Scholar
• Ogata N, Yamamoto H, Kugiyama K, et al. Involvement of protein kinase C in superoxide anion-induced activation of nuclear factor-kappa B in human endothelial cells. Cardiovasc Res. 2000;45(2):513–521.
   PubMed Web of Science ®Google Scholar
• Doughan AK, Harrison DG, Dikalov SI. Molecular mechanisms of angiotensin II-mediated mitochondrial dysfunction: linking mitochondrial oxidative damage and vascular endothelial dysfunction. Circ Res. 2008;102(4):488–496.
   PubMed Web of Science ®Google Scholar
• Zorov DB, Juhaszova M, Sollott SJ. Mitochondrial reactive oxygen species (ROS) and ROS-induced ROS release. Physiol Rev. 2014;94(3):909–950.
   PubMed Web of Science ®Google Scholar
• Li Y, Chang Y, Ye N, et al. Advanced glycation end products-induced mitochondrial energy metabolism dysfunction alters proliferation of human umbilical vein endothelial cells. Mol Med Rep. 2017;15(5):2673–2680.
   PubMed Web of Science ®Google Scholar
• Wang X, Jin A, An M, et al. Etomidate deteriorates the toxicity of advanced glycation end products to human endothelial Eahy926 cells. J Toxicol Sci. 2014;39(6):887–896.
   PubMed Web of Science ®Google Scholar
• Cano A, Arnao MB, Williamson G, et al. Superoxide scavenging by polyphenols: effect of conjugation and dimerization. Redox Rep. 2002;7(6):379–383.
   PubMed Web of Science ®Google Scholar
• Hung CH, Chan SH, Chu PM, et al. Quercetin is a potent anti-atherosclerotic compound by activation of SIRT1 signaling under oxLDL stimulation. Mol Nutr Food Res. 2015;59(10):1905–1917.
   PubMed Web of Science ®Google Scholar
• Bajpai VK, Alam MB, Ju MK, et al. Antioxidant mechanism of polyphenol-rich Nymphaea nouchali leaf extract protecting DNA damage and attenuating oxidative stress-induced cell death via Nrf2-mediated heme-oxygenase-1 induction coupled with ERK/p38 signaling pathway. Biomed Pharmacother. 2018;103:1397–1407.
   PubMed Web of Science ®Google Scholar
• Dueñas M, González-Manzano S, González-Paramás A, et al. Antioxidant evaluation of O-methylated metabolites of catechin, epicatechin and quercetin. J Pharm Biomed Anal. 2010;51(2):443–449.
   PubMed Web of Science ®Google Scholar
• Morand C, Crespy V, Manach C, et al. Plasma metabolites of quercetin and their antioxidant properties. Am J Physiol. 1998;275(1 Pt 2):R212–R219.
   PubMedGoogle Scholar