Sugar-derived AGEs accelerate pharyngeal pumping rate and increase the lifespan of Caenorhabditis elegans

References

• John WG, Lamb EJ. The Maillard or browning reaction in diabetes. Eye. 1993;7(2):230–237.
   PubMedGoogle Scholar
• Kasper M, Funk RH. Age-related changes in cells and tissues due to advanced glycation end products (AGEs). Arch Gerontol Geriatr. 2001;32(3):233–243.
   PubMed Web of Science ®Google Scholar
• Nass N, Bartling B, Navarrete Santos A, et al. Advanced glycation end products, diabetes and ageing. Z Gerontol Geriatr. 2007;40(5):349–356.
   PubMed Web of Science ®Google Scholar
• Badenhorst D, Maseko M, Tsotetsi OJ, et al. Cross-linking influences the impact of quantitative changes in myocardial collagen on cardiac stiffness and remodelling in hypertension in rats. Cardiovasc Res. 2003;57(3):632–641.
   PubMed Web of Science ®Google Scholar
• Chen JH, Lin X, Bu C, et al. Role of advanced glycation end products in mobility and considerations in possible dietary and nutritional intervention strategies. Nutr Metab. 2018;15:72.
   Google Scholar
• Takeuchi M, Takino J-I, Yamagishi S-I. Involvement of the toxic AGEs (TAGE)-RAGE system in the pathogenesis of diabetic vascular complications: a novel therapeutic strategy. Curr Drug Targets. 2010;11(11):1468–1482.
   PubMed Web of Science ®Google Scholar
• Henle T. Protein-bound advanced glycation endproducts (AGEs) as bioactive amino acid derivatives in foods. Amino Acids. 2005;29(4):313–322.
   PubMed Web of Science ®Google Scholar
• Scheijen JLJM, Clevers E, Engelen L, et al. Analysis of advanced glycation endproducts in selected food items by ultra-performance liquid chromatography tandem mass spectrometry: presentation of a dietary AGE database. Food Chem. 2016;190:1145–1150.
   PubMed Web of Science ®Google Scholar
• Nowotny K, Schröter D, Schreiner M, et al. Dietary advanced glycation end products and their relevance for human health. Ageing Res Rev. 2018;47:55–66.
   PubMed Web of Science ®Google Scholar
• Snelson M, Coughlan MT. Dietary advanced glycation end products: digestion, metabolism and modulation of gut microbial ecology. Nutrients. 2019;11(2).
   Web of Science ®Google Scholar
• Lazakovitch E, Kalb JM, Gronostajski RM. Lifespan extension and increased pumping rate accompany pharyngeal muscle-specific expression of nfi-1 in C. elegans. Dev Dyn. 2008;237(8):2100–2107.
   PubMed Web of Science ®Google Scholar
• Huang C, Xiong C, Kornfeld K. Measurements of age-related changes of physiological processes that predict lifespan of Caenorhabditis elegans. Proc Natl Acad Sci USA. 2004;101(21):8084–8089.
   PubMed Web of Science ®Google Scholar
• Trojanowski NF, Raizen DM, Fang-Yen C. Pharyngeal pumping in Caenorhabditis elegans depends on tonic and phasic signaling from the nervous system. Sci Rep. 2016;6:22940.
   PubMed Web of Science ®Google Scholar
• Zhang W, Cai L, Geng HJ, et al. Methyl 3,4-dihydroxybenzoate extends the lifespan of Caenorhabditis elegans, partly via W06A7.4 gene. Exp Gerontol. 2014;60:108–116.
   PubMed Web of Science ®Google Scholar
• Hamer G, Matilainen O, Holmberg CI. A photoconvertible reporter of the ubiquitin-proteasome system in vivo. Nat Methods. 2010;7(6):473–478.
   PubMed Web of Science ®Google Scholar
• Li X, Matilainen O, Jin C, et al. Specific SKN-1/Nrf stress responses to perturbations in translation elongation and proteasome activity. PLoS Genet. 2011;7(6):e1002119.
   PubMed Web of Science ®Google Scholar
• Matilainen O, Arpalahti L, Rantanen V, et al. Insulin/IGF-1 signaling regulates proteasome activity through the deubiquitinating enzyme UBH-4. Cell Rep. 2013;3(6):1980–1995.
   PubMed Web of Science ®Google Scholar
• Menzel R, Menzel S, Tiedt S, et al. Enrichment of humic material with hydroxybenzene moieties intensifies its physiological effects on the nematode Caenorhabditis elegans. Environ Sci Technol. 2011;45(20):8707–8715.
   PubMed Web of Science ®Google Scholar
• Bierhaus A, Fleming T, Stoyanov S, et al. Methylglyoxal modification of Nav1.8 facilitates nociceptive neuron firing and causes hyperalgesia in diabetic neuropathy. Nat Med. 2012;18(6):926–933.
   PubMed Web of Science ®Google Scholar
• Giacco F, Du X, D’Agati VD, et al. Knockdown of glyoxalase 1 mimics diabetic nephropathy in nondiabetic mice. Diabetes. 2014;63(1):291–299.
   PubMed Web of Science ®Google Scholar
• Münch G, Westcott B, Menini T, et al. Advanced glycation endproducts and their pathogenic roles in neurological disorders. Amino Acids. 2012;42(4):1221–1236.
   PubMed Web of Science ®Google Scholar
• Tsantoulas C, Laínez S, Wong S, et al. Hyperpolarization-activated cyclic nucleotide-gated 2 (HCN2) ion channels drive pain in mouse models of diabetic neuropathy. Sci Transl Med. 2017;9(409):eaam6072.
   PubMed Web of Science ®Google Scholar
• Ames JM. Evidence against dietary advanced glycation endproducts being a risk to human health. Mol Nutr Food Res. 2007;51(9):1085–1090.
   PubMed Web of Science ®Google Scholar
• Tamanna N, Mahmood N. Food processing and Maillard reaction products: effect on human health and nutrition. Int J Food Sci. 2015;2015:526762.
   PubMedGoogle Scholar
• Tsakiri EN, Iliaki KK, Höhn A, et al. Diet-derived advanced glycation end products or lipofuscin disrupts proteostasis and reduces life span in Drosophila melanogaster. Free Radic Biol Med. 2013;65:1155–1163.
   PubMed Web of Science ®Google Scholar
• Cai W, He JC, Zhu L, et al. Oral glycotoxins determine the effects of calorie restriction on oxidant stress, age-related diseases, and lifespan. Am J Pathol. 2008;173(2):327–336.
   PubMed Web of Science ®Google Scholar
• Ravichandran M, Priebe S, Grigolon G, et al. Impairing l-threonine catabolism promotes healthspan through methylglyoxal-mediated proteohormesis. Cell Metab. 2018;27(4):914–925.e5.
   PubMed Web of Science ®Google Scholar
• Liu C, Huang Y, Zhang Y, et al. Intracellular methylglyoxal induces oxidative damage to pancreatic beta cell line INS-1 cell through Ire1α-JNK and mitochondrial apoptotic pathway. Free Radic Res. 2017;51(4):337–350.
   PubMed Web of Science ®Google Scholar
• Grimm S, Ott C, Hörlacher M, et al. Advanced-glycation-end-product-induced formation of immunoproteasomes: involvement of RAGE and Jak2/STAT1. Biochem J. 2012;448(1):127–139.
   PubMedGoogle Scholar
• Aldini G, Domingues MR, Spickett CM, et al. Protein lipoxidation: detection strategies and challenges. Redox Biol. 2015;5:253–266.
   PubMed Web of Science ®Google Scholar
• Bulteau AL, Verbeke P, Petropoulos I, et al. Proteasome inhibition in glyoxal-treated fibroblasts and resistance of glycated glucose-6-phosphate dehydrogenase to 20 S proteasome degradation in vitro. J Biol Chem. 2001;276(49):45662–45668.
   PubMed Web of Science ®Google Scholar
• Grimm S, Horlacher M, Catalgol B, et al. Cathepsins D and L reduce the toxicity of advanced glycation end products. Free Radic Biol Med. 2012;52(6):1011–1023.
   PubMed Web of Science ®Google Scholar
• Grimm S, Ernst L, Grötzinger N, et al. Cathepsin D is one of the major enzymes involved in intracellular degradation of AGE-modified proteins. Free Radic Res. 2010;44(9):1013–1026.
   PubMed Web of Science ®Google Scholar
• Takahashi A, Takabatake Y, Kimura T, et al. Autophagy inhibits the accumulation of advanced glycation end products by promoting lysosomal biogenesis and function in the kidney proximal tubules. Diabetes. 2017;66(5):1359–1372.
   PubMed Web of Science ®Google Scholar
• Chaudhuri J, Bains Y, Guha S, et al. The role of advanced glycation end products in aging and metabolic diseases: bridging association and causality. Cell Metab. 2018;28(3):337–352.
   PubMed Web of Science ®Google Scholar
• Demishtein A, Fraiberg M, Berko D, et al. SQSTM1/p62-mediated autophagy compensates for loss of proteasome polyubiquitin recruiting capacity. Autophagy. 2017;13(10):1697–1708.
   PubMed Web of Science ®Google Scholar
• Ding WX, Ni HM, Gao W, et al. Linking of autophagy to ubiquitin-proteasome system is important for the regulation of endoplasmic reticulum stress and cell viability. Am J Pathol. 2007;171(2):513–524.
   PubMed Web of Science ®Google Scholar
• Fan T, Huang Z, Wang W, et al. Proteasome inhibition promotes autophagy and protects from endoplasmic reticulum stress in rat alveolar macrophages exposed to hypoxia-reoxygenation injury. J Cell Physiol. 2018;233(10):6748–6758.
   PubMed Web of Science ®Google Scholar
• Selimovic D, Porzig BB, El-Khattouti A, et al. Bortezomib/proteasome inhibitor triggers both apoptosis and autophagy-dependent pathways in melanoma cells. Cell Signal. 2013;25(1):308–318.
   PubMed Web of Science ®Google Scholar
• Wu WK, Wu YC, Yu L, et al. Induction of autophagy by proteasome inhibitor is associated with proliferative arrest in colon cancer cells. Biochem Biophys Res Commun. 2008;374(2):258–263.
   PubMed Web of Science ®Google Scholar
• Zheng Q, Su H, Tian Z, et al. Proteasome malfunction activates macroautophagy in the heart. Am J Cardiovasc Dis. 2011;1(3):214–226.
   PubMedGoogle Scholar
• Zhu K, Dunner K Jr., McConkey DJ. Proteasome inhibitors activate autophagy as a cytoprotective response in human prostate cancer cells. Oncogene. 2010;29(3):451–462.
   PubMed Web of Science ®Google Scholar
• Richarme G, Mihoub M, Dairou J, et al. Parkinsonism-associated protein DJ-1/Park7 is a major protein deglycase that repairs methylglyoxal- and glyoxal-glycated cysteine, arginine, and lysine residues. J Biol Chem. 2015;290(3):1885–1897.
   PubMed Web of Science ®Google Scholar
• Zheng J, Greenway FL, Heymsfield SB, et al. Effects of three intense sweeteners on fat storage in the C. elegans model. Chem Biol Interact. 2014;215:1–6.
   PubMed Web of Science ®Google Scholar
• Rose JK, Sangha S, Rai S, et al. Decreased sensory stimulation reduces behavioral responding, retards development, and alters neuronal connectivity in Caenorhabditis elegans. J Neurosci. 2005;25(31):7159–7168.
   PubMed Web of Science ®Google Scholar
• Guarente L, Kenyon C. Genetic pathways that regulate ageing in model organisms. Nature. 2000;408(6809):255–262.
   PubMed Web of Science ®Google Scholar
• Lin K, Hsin H, Libina N, et al. Regulation of the Caenorhabditis elegans longevity protein DAF-16 by insulin/IGF-1 and germline signaling. Nat Genet. 2001;28(2):139–145.
   PubMed Web of Science ®Google Scholar
• Putker M, Madl T, Vos HR, et al. Redox-dependent control of FOXO/DAF-16 by transportin-1. Mol Cell. 2013;49(4):730–742.
   PubMed Web of Science ®Google Scholar
• Kikuchi S, Shinpo K, Takeuchi M, et al. Glycation – a sweet tempter for neuronal death. Brain Res Brain Res Rev. 2003;41(2–3):306–323.
   PubMedGoogle Scholar
• Kikuchi S, Shinpo K, Tsuji S, et al. Effect of proteasome inhibitor on cultured mesencephalic dopaminergic neurons. Brain Res. 2003;964(2):228–236.
   PubMed Web of Science ®Google Scholar
• Golegaonkar S, Tabrez SS, Pandit A, et al. Rifampicin reduces advanced glycation end products and activates DAF-16 to increase lifespan in Caenorhabditis elegans. Aging Cell. 2015;14(3):463–473.
   PubMed Web of Science ®Google Scholar
• Morcos M, Du X, Pfisterer F, et al. Glyoxalase-1 prevents mitochondrial protein modification and enhances lifespan in Caenorhabditis elegans. Aging Cell. 2008;7(2):260–269.
   PubMed Web of Science ®Google Scholar
• Mendler M, Schlotterer A, Ibrahim Y, et al. daf-16/FOXO and glod-4/glyoxalase-1 are required for the life-prolonging effect of human insulin under high glucose conditions in Caenorhabditis elegans. Diabetologia. 2015;58(2):393–401.
   PubMed Web of Science ®Google Scholar
• Diamanti-Kandarakis E, Chatzigeorgiou A, Papageorgiou E, et al. Advanced glycation end-products and insulin signaling in granulosa cells. Exp Biol Med (Maywood). 2016;241(13):1438–1445.
   PubMed Web of Science ®Google Scholar
• Park D, Hahm JH, Park S, et al. A conserved neuronal DAF-16/FoxO plays an important role in conveying pheromone signals to elicit repulsion behavior in Caenorhabditis elegans. Sci Rep. 2017;7(1):7260.
   PubMedGoogle Scholar