Relationship between toxicity and oxidative stress of the nanoencapsulated colchicine in a model of Drosophila melanogaster

References

• Nosengo N. Can you teach old drugs new tricks? Nature. 2016;534(7607):314–316.
   PubMed Web of Science ®Google Scholar
• Pushpakom S, Iorio F, Eyers PA, et al. Drug repurposing: progress, challenges and recommendations. Nat Rev Drug Discov. 2019;18(1):41–58.
   PubMed Web of Science ®Google Scholar
• Han HJ, Nwagwu C, Anyim O, et al. COVID-19 and cancer: from basic mechanisms to vaccine development using nanotechnology. Int Immunopharmacol. 2021;90:107247.
   PubMed Web of Science ®Google Scholar
• Huang C, Wang Y, Li X, et al. Clinical features of patients infected with 2019 novel coronavirus in Wuhan, China. Lancet. 2020;395(10223):497–506.
   PubMed Web of Science ®Google Scholar
• Nasiripour S, Zamani F, Farasatinasab M. Can colchicine as an old anti-Inflammatory agent be effective in COVID-19? J Clin Pharmacol. 2020;60(7):828–829.
   PubMed Web of Science ®Google Scholar
• Asselah T, Durantel D, Pasmant E, et al. COVID-19: discovery, diagnostics and drug development. J Hepatol. 2021;74(1):168–184.
   PubMed Web of Science ®Google Scholar
• Dinarello CA, Wolff SM, Goldfinger SE, et al. Colchicine therapy for familial Mediterranean fever: a double-blind trial. N Engl J Med. 1974;291(18):934–937.
   PubMed Web of Science ®Google Scholar
• Georgin-Lavialle S, Hentgen V, Stankovic Stojanovic K, et al. Familial mediterranean fever. Rev Med Intern. 2018;39(4):240–255.
   PubMed Web of Science ®Google Scholar
• Dalbeth N, Lauterio TJ, Wolfe HR. Mechanism of action of colchicine in the treatment of gout. Clin Ther. 2014;36(10):1465–1479.
   PubMed Web of Science ®Google Scholar
• Ravelli RB, Gigant B, Curmi PA, et al. Insight into tubulin regulation from a complex with colchicine and a stathmin-like domain. Nature. 2004;428(6979):198–202.
   PubMed Web of Science ®Google Scholar
• Lopes MI, Bonjorno LP, Giannini MC, et al. Beneficial effects of colchicine for moderate to severe COVID-19: a randomised, double-blinded, placebo-controlled clinical trial. RMD Open. 2021;7(1):e001455.
   PubMed Web of Science ®Google Scholar
• Rodrigues TS, de Sá KSG, Ishimoto AY, et al. Inflammasomes are activated in response to SARS-CoV-2 infection and are associated with COVID-19 severity in patients. J Exp Med. 2021;218:e20201707.
   PubMed Web of Science ®Google Scholar
• Gonnet M, Lethuaut L, Boury F. New trends in encapsulation of liposoluble vitamins. J Control Release. 2010;146(3):276–290.
   PubMed Web of Science ®Google Scholar
• Kumari A, Singla R, Guliani A, et al. Nanoencapsulation for drug delivery. EXCLI J. 2014;13:265–286.
   PubMed Web of Science ®Google Scholar
• Pappus SA, Mishra M. A Drosophila model to decipher the toxicity of nanoparticles taken through oral routes. Adv Exp Med Biol. 2018;1048:311–322.
   PubMed Web of Science ®Google Scholar
• Ong C, Yung LY, Cai Y, et al. Drosophila melanogaster as a model organism to study nanotoxicity. Nanotoxicology. 2015;9(3):396–403.
   PubMed Web of Science ®Google Scholar
• Eriksson P, Tal AA, Skallberg A, et al. Cerium oxide nanoparticles with antioxidant capabilities and gadolinium integration for MRI contrast enhancement. Sci Rep. 2018;8(1):12.
   PubMedGoogle Scholar
• Misra JR, Horner MA, Lam G, et al. Transcriptional regulation of xenobiotic detoxification in Drosophila. Genes Dev. 2011;25(17):1796–1806.
   PubMed Web of Science ®Google Scholar
• Venturini CG, Jäger E, Oliveira CP, et al. Formulation of lipid core nanocapsules. Colloids Surf A. 2011;375(1–3):200–208.
   Google Scholar
• Sood K, Kaur J, Singh H, et al. Comparative toxicity evaluation of graphene oxide (GO) and zinc oxide (ZnO) nanoparticles on Drosophila melanogaster. Toxicol Rep. 2019;6:768–781.
   PubMed Web of Science ®Google Scholar
• Linford NJ, Bilgir C, Ro J, et al. Measurement of Lifespan in Drosophila melanogaster. JoVE. 2013;(71)10.3791/50068.
   Google Scholar
• Hirth F. Drosophila melanogaster in the study of human neurodegeneration. CNS Neurol Disord Drug Targets. 2010;9(4):504–523.
   PubMed Web of Science ®Google Scholar
• Pérez-Severiano F, Santamaría A, Pedraza-Chaverri J, et al. Increased formation of reactive oxygen species, but no changes in glutathione peroxidase activity, in striata of mice transgenic for the Huntington’s disease mutation. Neurochem Res. 2004;29(4):729–733.
   PubMed Web of Science ®Google Scholar
• Ohkawa H, Ohishi N, Yagi K. Assay for lipid peroxides in animal tissues by thiobarbituric acid reaction. Anal Biochem. 1979;95(2):351–358.
   PubMed Web of Science ®Google Scholar
• Ellman GL, Courtney KD, Andres V, Jr, et al. A new and rapid colorimetric determination of acetylcholinesterase activity. Biochem Pharmacol. 1961;7:88–95.
   PubMed Web of Science ®Google Scholar
• Aebi H. Catalase in vitro. Methods Enzymol. 1984;105:121–126.
   PubMed Web of Science ®Google Scholar
• Misra HP, Fridovich I. The role of superoxide anion in the autoxidation of epinephrine and a simple assay for superoxide dismutase. J Biol Chem. 1972;247(10):3170–3175.
   PubMed Web of Science ®Google Scholar
• Sun M, Zigman S. An improved spectrophotometric assay for superoxide dismutase based on epinephrine autoxidation. Anal Biochem. 1978;90(1):81–89.
   PubMed Web of Science ®Google Scholar
• Habig WH, Pabst MJ, Jakoby WB. Glutathione S-transferases. The first enzymatic step in mercapturic acid formation. J Biol Chem. 1974;249(22):7130–7139.
   PubMed Web of Science ®Google Scholar
• Brien J, et al. Investigation of the Alamar Blue (resazurin) fluorescent dye for the assessment of mammalian cell cytotoxicity. Eur J Biochem. 2000;267(17):5421–5426.[AQ]
   PubMedGoogle Scholar
• Ellman A. Tissue sulfhydryl groups. Arch Biochem Biophys. 1959;82(1):70–77.
   PubMed Web of Science ®Google Scholar
• Bradford MM. A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding. Anal Biochem. 1976;72:248–254.
   PubMed Web of Science ®Google Scholar
• Balaban RS, Nemoto S, Finkel T. Mitochondria, oxidants, and aging. Cell. 2005;120(4):483–495.
   PubMed Web of Science ®Google Scholar
• Isaenko OA, Karr TL, Feder ME. Hsp70 and thermal pretreatment mitigate developmental damage caused by mitotic poisons in Drosophila. Cell Stress Chaper. 2002;7(3):297–308.
   PubMed Web of Science ®Google Scholar
• Tian H, Eom HJ, Moon S, et al. Development of biomarker for detecting silver nanoparticles exposure using a GAL4 enhancer trap screening in Drosophila. Environ Toxicol Pharmacol. 2013;36(2):548–556.
   PubMed Web of Science ®Google Scholar
• Birben E, Murat U, Md S, et al. Oxidative stress and antioxidant defense. WAO J. 2012;5:9–19.
   Google Scholar
• Huang HY, Appel LJ, Croft KD, et al. Effects of vitamin C and vitamin E on in vivo lipid peroxidation: results of randomized controlled trial. Am J Clin Nutr. 2002;76(3):549–555.
   PubMed Web of Science ®Google Scholar
• Abdal Dayem A, Hossain MK, Lee SB, et al. The role of reactive oxygen species (ROS) in the biological activities of metallic nanoparticles. IJMS. 2017;18(1):120.
   Google Scholar
• Mishra M, Panda M. Reactive oxygen species: the root cause of nanoparticle-induced toxicity in Drosophila melanogaster. Free Radic Res. 2021;55(6):671–687.
   PubMed Web of Science ®Google Scholar
• Yang M, Lv H, Liu Q, et al. Colchicine alleviates cholesterol crystal-induced endothelial cell pyroptosis through activating AMPK/SIRT1 pathway. Oxid Med Cell Longev. 2020;2020:9173530.
   PubMed Web of Science ®Google Scholar
• Ghani MA, Barril C, Bedgood DR, Jr, et al. Measurement of antioxidant activity with the thiobarbituric acid reactive substances assay. Food Chem. 2017;230:195–207.
   PubMed Web of Science ®Google Scholar
• Jahromi SR, Haddadi M, Shivanandappa T, et al. Neuroprotective effect of Decalepis hamiltonii in paraquat-induced neurotoxicity in Drosophila melanogaster: biochemical and behavioral evidences. Neurochem Res. 2013;38(12):2616–2624.
   PubMed Web of Science ®Google Scholar
• Pandey A, Chandra S, Chauhan LK, et al. Cellular internalization and stress response of ingested amorphous silica nanoparticles in the midgut of Drosophila melanogaster. Biochim Biophys Acta. 2013;1830(1):2256–2266.
   PubMed Web of Science ®Google Scholar
• Yasuyama K, Salvaterra PM. Localization of choline acetyltransferase-expressing neurons in Drosophila nervous system. Microsc Res Tech. 1999;45(2):65–79.
   PubMed Web of Science ®Google Scholar
• Mukherjee PK, Kumar V, Mal M, et al. Acetylcholinesterase inhibitors from plants. Phytomedicine. 2007;14(4):289–300.
   PubMed Web of Science ®Google Scholar
• Moser VC. Dose-response and time-course of neurobehavioral changes following oral chlorpyrifos in rats of different ages. Neurotoxicol Teratol. 2000;22(5):713–723.
   PubMed Web of Science ®Google Scholar
• Fridovich I. Superoxide anion radical (O2-), superoxide dismutases, and related matters. J Biol Chem. 1997;272(30):18515–18517.
   PubMed Web of Science ®Google Scholar
• Wang Y, Branicky R, Noë A, et al. Superoxide dismutases: dual roles in controlling ROS damage and regulating ROS signaling. J Cell Biol. 2018;217(6):1915–1928.
   PubMed Web of Science ®Google Scholar
• Tschopp J, Schroder K. NLRP3 inflammasome activation: the convergence of multiple signalling pathways on ROS production? Nat Rev Immunol. 2010;10(3):210–215.
   PubMed Web of Science ®Google Scholar
• Yang W, Li J, Hekimi S. A measurable increase in oxidative damage due to reduction in superoxide detoxification fails to shorten the life span of long-lived mitochondrial mutants of Caenorhabditis elegans. Genetics. 2007;177(4):2063–2074.
   PubMed Web of Science ®Google Scholar
• Mitozo PA, de Souza LF, Loch-Neckel G, et al. A study of the relative importance of the peroxiredoxin-, catalase-, and glutathione-dependent systems in neural peroxide metabolism. Free Radic Biol Med. 2011;51(1):69–77.
   PubMed Web of Science ®Google Scholar
• Latunde-Dada GO. Ferroptosis: role of lipid peroxidation, iron and ferritinophagy. Biochim Biophys Acta Gen Subj. 2017;1861(8):1893–1900.
   PubMed Web of Science ®Google Scholar
• El-Rashid M, Nguyen-Ngo D, Minhas N, et al. Repurposing of metformin and colchicine reveals differential modulation of acute and chronic kidney injury. Sci Rep. 2020;10(1):21968.
   PubMed Web of Science ®Google Scholar
• Drasler B, Sayre P, Steinhäuser KG, et al. In vitro approaches to assess the hazard of nanomaterials. Nano Impact. 2017;8:99–116.
   Google Scholar
• Woodruff MA, Hutmacher DW. The return of a forgotten polymer - polycaprolactone in the 21st century. Prog Polym Sci. 2010;35(10):1217–1256. 2010
   Web of Science ®Google Scholar
• Bao W, Liu R, Wang Y, et al. PLGA-PLL-PEG-Tf-based targeted nanoparticles drug delivery system enhance antitumor efficacy via intrinsic apoptosis pathway. Int J Nanomedicine. 2015;10:557–566.
   PubMed Web of Science ®Google Scholar
• Missaoui WN, Arnold RD, Cummings BS. Toxicological status of nanoparticles: what we know and what we don’t know. Chem Biol Interact. 2018;295:1–12.
   PubMed Web of Science ®Google Scholar
• Hirayama I, Hiruma T, Ueda Y, et al. A critically ill patient after a colchicine overdose below the lethal dose: a case report. J Med Case Rep. 2018;12(1):191.
   PubMedGoogle Scholar
• Cho EJ, Holback H, Liu KC, et al. Nanoparticle characterization: state of the art, challenges, and emerging technologies. Mol Pharm. 2013;10(6):2093–2110.
   PubMed Web of Science ®Google Scholar