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Original Article

The role of protein phosphatases in the regulation of mitogen and stress-activated protein kinases

Pages 341-349 | Received 22 Mar 1999, Published online: 07 Jul 2009

References

  • Nishida E., Gotoh Y. The MAP kinase cascade is essential for diverse signal transduction pathways. Trends in Biochemical Sciences 1993; 18: 128–131
  • Marshall C.J. MAP kinase kinase kinase, MAP kinase kinase and MAP kinase. Current Opinion in Genetics and Development 1994; 4: 82–89
  • Robinson M.J., Cobb M.H. Mitogen-activated protein kinase pathways. Current Opinion in Cell Biology 1997; 9: 180–186
  • Cohen P. The search for physiological substrates of the MAP and SAP kinases in mammalian cells. Trends in Cell Biology 1997; 7: 353–361
  • Cobb M.H., Hepler J.E., Cheng M., Robbins D. The mitogen activated protein-kinases, ERK1 and ERK2. Seminars in Cancer Biology 1994; 5: 261–268
  • Lee J.-D., Ulevitch R.J., Han J. Primary structure of BMK1: a new mammalian MAP kinase. Biochemical and Biophysical Research Communications 1995; 213: 715–724
  • Zhou G., Bao Z.Q., Dixon J.E. Components of a new human protein kinase signal transduction pathway. The Journal of Biological Chemistry 1995; 270: 12665–12669
  • Abe M.K., Kuo W.-L., Hershenson M.B., Rosner M.R. Extracellular signal-regulated kinase 7 (ERK7), a novel ERK with a C-terminal domain that regulates its activity, its cellular localisation and cell growth. Molecular and Cellular Biology 1999; 19: 1301–1312
  • Wasylyk B., Hagman J., Gutierrez-Hartmann A. Ets transcription factors: nuclear effectors of the ras-MAP kinase signaling pathway. Trends in Biochemical Sciences 1998; 23: 213–216
  • Khokhlatchev A.V., Canagarajah B., Wilsbacher J., Robinson M., Atkinson M., Goldsmith E., Cobb M.H. Phosphorylation of the MAP kinase ERK2 promotes its homodimerisation and nuclear translocation. Cell 1998; 108: 605–615
  • Marshall C.J. Specificity of receptor tyrosine kinase signalling: Transient versus sustained extracellular signal regulated kinase activation. Cell 1995; 80: 179–185
  • Traverse S., Gomez N., Paterson H., Marshall C., Cohen P. Sustained activation of the mitogen-activated protein (MAP) kinase cascade may be required for differentiation of PC12 cells. Comparison of the effects of nerve growth factor and epidermal growth factor. The Biochemical Journal 1992; 288: 351–355
  • Keyse S.M., Emslie E.A. Oxidative stress and heat shock induce a human gene encoding a protein tyrosine phosphatase. Nature 1992; 359: 644–647
  • Keyse S.M., Ginsburg M. Amino acid similarity between CL100, a dual specificity MAP kinase phosphatase and cdc25. Trends in Biochemical Sciences 1993; 18: 377–378
  • Alessi D.R., Smythe C., Keyse S.M. The human CL100 gene encodes a Tyr/Thr-protein phosphatase which potently and specifically inactivates MAP kinase and suppresses its activation by oncogenic ras in Xenopus oocyte extracts. Oncogene 1993; 8: 2015–2020
  • Sun H., Charles C.H., Lau L.F., Tonks N.K. MKP-1(3CH134), an immediate early gene product, is a dual specificity phosphatase that dephosphorylates MAP kinase in vivo. Cell 1993; 75: 487–493
  • Herskowitz I. MAP kinase pathways in yeast: For mating and more. Cell 1995; 80: 187–197
  • Doi K., Gartner A., Ammerer G., Errede B., Shinkawa H., Sugimoto K., Matsumoto K. MSG5, a novel protein phosphatase promotes adaptation to pheromone. The EMBO Journal 1994; 13: 61–70
  • Martin-Blanco E., Gampel A., Ring J., Virdee K., Kirov N., Tolkovsky A.M., Martinez-Ariaz A. Puckered encodes aphosphatase that mediates a feedback loop regulating JNK activity during dorsal closure in Drosophila. Genes and Development 1998; 12: 557–570
  • Keyse S.M. An emerging family of dual-specificity MAP kinase phosphatases. Biochimica et Biophysica Acta 1995; 1265: 152–160
  • Groom L.A., Sneddon A.A., Alessi D.R., Dowd S., Keyse S.M. Differential regulation of the MAP,SAP and RK/p38 kinases by Pyst1, a novel cytoplasmic dual-specificity phosphatase. The EMBO Journal 1996; 15: 3621–3632
  • Muda M., Boschert U., Dickinson R., Martinou J.-C., Martinou I., Camps M., Schlegel W., Arkinstall S. MKP-3, a novel cytosolic protein tyrosine phosphatase that exemplifies a new class of mitogen-activated protein kinase phosphatase. The Journal of Biological Chemistry 1996; 271: 4319–4326
  • Mourey R.J., Vega Q.C., Campbell J.S., Wenderoth M.P., Hauschka S.D., Krebs E.G., Dixon J.E. A novel cytoplasmic dual specificity protein tyrosine phosphatase implicated in muscle and neuronal differentiation. The Journal of Biological Chemistry 1996; 271: 3795–3802
  • Dowd S., Sneddon A.A., Keyse S.M. Isolation of the human genes encoding the Pyst1 and Pyst2 phosphatases: characterisation of Pyst2 as a cytosolic dual-specificity MAP kinase phosphatase and its catalytic activation by both MAP and SAP kinases. Journal of Cell Science 1998; 111: 3389–3399
  • Muda M., Boschert U., Smith A., Antonsson B., Gillieron C., Chabert C., Camps M., Martinou I., Ashworth A., Arkinstall S. Molecular cloning and functional characterisation of a novel mitogenactivated protein kinase phosphatase, MKP-4. The Journal of Biological Chemistry 1997; 272: 5141–5151
  • Theodosiou A.M., Rodrigues N.R., Nesbitt M.A., Ambrose H.J., Paterson H., McLellan-Arnold E., Boyd Y., Leversha M.A., Owen N., Blake D.J., Ashworth A., Davies K.E. A member of the MAP kinase phosphatase gene family in mouse containing a complex trinucleotide repeat in the coding region. Human Molecular Genetics 1996; 5: 675–684
  • Martell K.J., Seasholz A.F., Kwak S.P., Clemens K.K., Dixon J.E. hVH-5: A protein tyrosine phosphatase abundant in brain that inactivates mitogenactivated protein kinase. The Journal of Neurochemistry 1995; 65: 1823–1833
  • Muda M., Theodosiou A., Rodrigues N., Boschert U., Camps M., Gillieron C., Davies K., Ashworth A., Arkinstall S. The dual specificity phosphatases M3/6 and MKP-3 are highly selective for the inactivation of distinct mitogen-activated protein kinases. The Journal of Biological Chemistry 1996; 271: 27205–27208
  • Chu Y., Solski P.A., Khosravi-Far R., Der C.J., Kelly K. The mitogen-activated protein kinase phosphatases PAC1, MKP-1 and MKP-2 have unique substrate specificities and reduced activity in vivo towards the ERK2 sevenmaker mutation. The Journal of Biological Chemistry 1996; 271: 6497–6501
  • Muda M., Theodosiou A., Gillieron C., Smith A., Chabert C., Camps M., Boschert U., Rodrigues N., Davies K., Ashworth A., Arkinstall S. The mitogen-activated protein-kinase phosphatase-3 N-terminal noncatalytic region is responsible for tight substrate-binding and enzymatic specificity. The Journal of Biological Chemistry 1998; 273: 9323–9329
  • Camps M., Nichols A., Gillieron C., Antonsson B., Muda M., Chabert C., Boschert U., Arkinstall S. Catalytic activation of the phosphatase MKP-3 by ERK2 mitogen-activated protein kinase. Science 1998; 280: 1262–1265
  • Stewart A.E., Dowd S., Keyse S.M., McDonald N.Q. Crystal structure of the MAPK phosphatase Pyst1 catalytic domain and implications for regulated activation. Nature Structural Biology 1999; 6: 174–181
  • Yuvaniyama J., Denu J.M., Dixon J.E., Saper M.A. Crystal structure of the dual-specificity protein phosphatase VHR. Science 1996; 272: 1328–1331
  • Fauman E.B., Cogswell J.P., Lovejoy B., Rocque W.J., Holmes W., Montana V.G., Piwicna-Worms H., Rink M.J., Saper M.A. Crystal structure of the catalytic domain of the human cell cycle control phosphatase, cdc25A. Cell 1998; 93: 617–625
  • Fauman E.B., Saper M.A. Structure and function of the protein tyrosine phosphatases. Trends in Biochemical Sciences 1996; 21: 413–417
  • Denu J.M., Lohse D.L, Vijayalaksmi J., Saper M.A., Dixon J.E. Visualisation of intermediate and transition-state structures in protein tyrosine phosphatase catalysis. Proceedings of the National Academy of Sciences USA 1996; 93: 2493–2498
  • Wurgler-Murphy S.M., Maeda T., Witten E.A., Saito H. Regulation of the Saccharomyces cerevisiae HOG1 mitogen-activated protein-kinase by the PTP2 and PTP3 protein-tyrosine phosphatases. Molecular and Cellular Biology 1997; 17: 1289–1297
  • Jacoby T., Flanagan H., Faykin A., Seto A.G., Mattison C., Ota I. Two protein-tyrosine phosphatases inactivate the osmotic-stress response pathway in yeast by targeting the mitogen-activated protein kinase, Hog 1. The Journal of Biological Chemistry 1997; 272: 17749–17755
  • Millar J.B.A., Buck V., Willinson M.G. Pyp1 and pyp2 PTPases dephosphorylate an osmosensing MAP kinase controlling cell-size at division in fission yeast. Genes and Development 1995; 9: 2117–2130
  • Shiozaki K., Russell P. Cell-cycle control linked to extracellular environment by MAP kinase pathway in fission yeast. Nature 1995; 378: 739–743
  • Zhan X.L., Deschenes R.J., Guan K.L. Differential regulation of FUS3 map kinase by tyrosine-specific phosphatases PTP2/PTP3 and dual-specificity phosphatase Msg5 in Saccharomyces cerevisiae. Genes and Development 1997; 11: 1690–1702
  • Alessi D.R, Gomez N., Moorhead G., Lewis T., Keyse S.M., Cohen P. Inactivation of p42 MAP kinase by protein phosphatase 2A and a protein tyrosine phosphatase, but not CL100 in various cell lines. Current Biology 1995; 5: 283–295
  • Sarcevic B., Erikson E., Maller J.L. Purification and characterisation of a mitogen-activated protein kinase phosphatase from Xenopus eggs. The Journal of Biological Chemistry 1993; 268: 25075–25083
  • Pulido R., Zuniga A., Ullrich A. PTP-SL and STEP protein tyrosine phosphatases regulate the activation of the extracellular signal-regulated kinases ERK1 and ERK2 by association through a kinase interaction motif. The EMBO Journal 1998; 17: 7337–7350
  • Maeda T., Wurgler-Murphy S.M., Saito H. A two-component system that regulates an osmosensing MAP kinase cascade in yeast. Nature 1994; 369: 242–245
  • Shiozaki K., Russell P. Counteractive roles of protein phosphatase 2C (PP2C) and a MAP kinase kinase homolog in the osmoregulation of fission yeast. The EMBO Journal 1995; 14: 492–502
  • Gaits F., Shiozaki K., Russell P. Protein phosphatase 2C acts independently of stress activated kinase cascade to regulate the stress response in fission yeast. The Journal of Biological Chemistry 1997; 272: 17873–17879
  • Takekawa M., Maeda T., Saito H. Protein phosphatase 2Cα inhibits the human stress-responsive p38 and JNK MAPK pathways. The EMBO Journal 1998; 17: 4744–4752

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