In-depth study of anticancer drug diffusion through a cross-linked ­pH-responsive polymeric vesicle membrane

References

• Bories-Azeau X, Armes SP, van den Haak HJW. (2004). Facile synthesis of zwitterionic diblock copolymers without protecting group chemistry. Macromolecules 37:1–11.
   Web of Science ®Google Scholar
• Che H, van Hest JCM. (2016). Stimuli-responsive polymersomes and nanoreactors. J Mater Chem B 4:4632–47.
   PubMed Web of Science ®Google Scholar
• Chen W, Meng FH, Cheng R, Zhong ZY. (2010). pH-sensitive degradable polymersomes for triggered release of anticancer drugs: a comparative study with micelles. J Control Release 142:40–6.
   PubMed Web of Science ®Google Scholar
• Colley HE, Hearnden V, Avila-Olias M, Cecchin D, Canton I, Madsen J, MacNeil S, Warren N, Hu K, McKeating JA, Armes SP, Murdoch C, Thornhill MH, Battaglia G. (2014). Polymersome-mediated delivery of combination anticancer therapy to head and neck cancer cells: 2D and 3D in vitro evaluation. Mol Pharm 11:1176–88.
   PubMed Web of Science ®Google Scholar
• Dai XC, Yu LL, Zhang YX, Zhang L, Tan JB. (2019). Polymerization-induced self-assembly via RAFT-mediated emulsion polymerization of methacrylic monomers. Macromolecules 52:7468–76.
   Web of Science ®Google Scholar
• Deane OJ, Musa OM, Fernyhough A, Armes SP. (2020). Synthesis and characterization of waterborne pyrrolidone functional diblock copolymer nanoparticles prepared via surfactant-free RAFT emulsion polymerization. Macromolecules 53:1422–34.
   Web of Science ®Google Scholar
• Du Y, Jia S, Chen Y, Zhang L, Tan JB. (2021). Type I photoinitiator-functionalized block copolymer nanoparticles prepared by RAFT-mediated polymerization-induced self-assembly. ACS Macro Lett 10:297–306.
   PubMed Web of Science ®Google Scholar
• Feng A, Yuan J. (2014). Smart nanocontainers: progress on novel stimuli-responsive polymer vesicles. Macromol Rapid Commun 35:767–79.
   PubMed Web of Science ®Google Scholar
• Fox ME, Szoka FC, Frechet JM. (2009). Soluble polymer carriers for the treatment of cancer: the importance of molecular architecture. Acc Chem Res 42:1141–51.
   PubMed Web of Science ®Google Scholar
• Gao C, Wang Y, Zhu WP, Shen ZQ. (2014). Resorcinarene-centered amphiphilic star-block copolymers: synthesis, micellization and controlled drug release. Chin J Polym Sci 32:1431–41.
   Web of Science ®Google Scholar
• Gu Y, Zhao J, Liu Q, Zhou N, Zhang Z, Zhu X. (2014). Zero-valent iron (Fe(0)) mediated RAFT miniemulsion polymerization: a facile approach for the fabrication of Fe(0)-encapsulated polymeric nanoparticles. Polym Chem 5:4215–8.
   Web of Science ®Google Scholar
• Gu Y, Zhao J, Liu Q, Pan X, Zhang W, Zhang Z, Zhu X. (2015). Zero valent metal/RAFT agent mediated CRP of functional monomers at room temperature: a promising catalyst system for CRP. Polym Chem 6:359–63.
   Web of Science ®Google Scholar
• Hu XL, Tian J, Liu T, Zhang GY, Liu SY. (2013). Photo-triggered release of caged camptothecin prodrugs from dually responsive shell cross-linked micelles. Macromolecules 46:6243–56.
   Web of Science ®Google Scholar
• Hu XL, Zhai SD, Liu GH, Xing D, Liang HJ, Liu SY. (2018). Concurrent drug unplugging and permeabilization of polyprodrug-gated crosslinked vesicles for cancer combination chemotherapy. Adv Mater 30:1706307.
   Web of Science ®Google Scholar
• Hu XL, Zhang YG, Xie ZG, Jing XB, Bellotti A, Gu Z. (2017). Stimuli-responsive polymersomes for biomedical applications. Biomacromolecules 18:649–73.
   PubMed Web of Science ®Google Scholar
• Kamaly N, Yameen B, Wu J, Farokhzad OC. (2016). Degradable controlled-release polymers and polymeric nanoparticles: mechanisms of controlling drug release. Chem Rev 116:2602–63.
   PubMed Web of Science ®Google Scholar
• Karagoz B, Esser L, Duong HT, Basuki JS, Boyer C, Davis TP. (2014). Polymerization-induced self-assembly (PISA)-control over the morphology of nanoparticles for drug delivery applications. Polym Chem 5:350–5.
   Web of Science ®Google Scholar
• Kim BS, Chuanoi S, Suma T, Anraku Y, Hayashi K, Naito M, Kim HJ, Kwon IC, Miyata K, Kishimura A, Kataoka K. (2019). Self-assembly of siRNA/PEG-b-catiomer at integer molar ratio into 100 nm-sized vesicular polyion complexes (siRNAsomes) for RNAi and codelivery of cargo macromolecules. J Am Chem Soc 141:3699–709.
   PubMed Web of Science ®Google Scholar
• Lee JS, Feijen J. (2012). Polymersomes for drug delivery: design, formation and characterization. J Control Release 161:473–83.
   PubMed Web of Science ®Google Scholar
• Li X, Yang WJ, Zou Y, Meng FH, Deng C, Zhong ZY. (2015). Efficacious delivery of protein drugs to prostate cancer cells by PSMA-targeted pH-responsive chimaeric polymersomes. J Control Release 220:704–14.
   PubMed Web of Science ®Google Scholar
• Liu X, Formanek P, Voit B, Appelhans D. (2017). Functional cellular mimics for the spatiotemporal control of multiple enzymatic cascade reactions. Angew Chem 129:16451–6.
   Google Scholar
• Liu Z, Lv Y, An ZS. (2017). Enzymatic cascade catalysis for the synthesis of multiblock and ultrahighmolecular-weight polymers with oxygen tolerance. Angew Chem Int Ed 56:13852–6.
   PubMed Web of Science ®Google Scholar
• Liu S, Maheshwari R, Kiick KL. (2009). Polymer-based therapeutics. Macromolecules 42:3–13.
   PubMed Web of Science ®Google Scholar
• Liu GY, Qiu Q, Shen WQ, An ZS. (2011). Aqueous dispersion polymerization of 2-methoxyethyl acrylate for the synthesis of biocompatible nanoparticles using a hydrophilic RAFT polymer and a redox initiator. Macromolecules 44:5237–45.
   Web of Science ®Google Scholar
• Liu GH, Tan JJ, Cen J, Zhang GY, Hu JM, Liu SY. (2022). Oscillating the local milieu of polymersome interiors via single input-regulated bilayer crosslinking and permeability tuning. Nat Commun 13:585.
   PubMed Web of Science ®Google Scholar
• Li Hz, Xu W, Li F, Zeng R, Zhang XM, Wang XW, Zhao SJ, Weng J, Li Z, Sun LP. (2022). Amplification of anticancer efficacy by co-delivery of doxorubicin and lonidamine with extracellular vesicles. Drug Deliv 29:192–202.
   PubMed Web of Science ®Google Scholar
• Lomas H, Canton I, MacNeil S, Du JZ, Armes SP, Ryan AJ, Lewis AL, Battaglia G. (2007). Biomimetic pH sensitive polymersomes for efficient DNA encapsulation and delivery. Adv Mater 19:4238–43.
   Web of Science ®Google Scholar
• Lv Y, Liu Z, Zhu A, An ZS. (2017). Glucose oxidase deoxygenation-redox initiation for RAFT polymerization in air. J Polym Sci Part A: Polym Chem 55:164–74.
   Web of Science ®Google Scholar
• Moreno S, Voit B, Gaitzsch J. (2021). The chemistry of cross-linked polymeric vesicles and their functionalization towards biocatalytic nanoreactors. Colloid Polym Sci 299:309–24.
   Web of Science ®Google Scholar
• Park M, Kim K, Mohanty AK, Cho HY, Lee H, Kang Y, Seo B, Lee W, Jeon HB, Paik HJ. (2020). Redox-initiated reversible addition-fragmentation chain transfer (RAFT) miniemulsion polymerization of styrene using PPEGMA-based macro-RAFT agent. Macromol Rapid Commun 41:2000399.
   Web of Science ®Google Scholar
• Peer D, Karp JM, Hong S, Farokhzad OC, Margalit R, Langer R. (2007). Nanocarriers as an emerging platform for cancer therapy. Nat Nanotechnol 2:751–60.
   PubMed Web of Science ®Google Scholar
• Penfold NJW, Whatley JR, Armes SP. (2019). Thermoreversible block copolymer worm gels using binary mixtures of PEG stabilizer blocks. Macromolecules 52:1653–62.
   Web of Science ®Google Scholar
• Qiu L, Xu CR, Zhong F, Hong CY, Pan CY. (2016). Fabrication of functional nano-objects through RAFT dispersion polymerization and influences of morphology on drug delivery. ACS Appl Mater Interfaces 8:18347–59.
   PubMed Web of Science ®Google Scholar
• Sztandera K, Gorzkiewicz M, Wang X, Boye S, Appelhans D, Klajnert-Maculewicz B. (2022). pH-stable polymersome as nanocarrier for post-loaded rose bengal in photodynamic therapy. Colloids Surf B Biointerfaces 217:112662.
   PubMed Web of Science ®Google Scholar
• Tan JB, Zhang X, Liu D, Bai Y, Huang C, Li X, Zhang L. (2017). Facile preparation of CO2-responsive polymer nano-objects via aqueous photoinitiated polymerization-induced self-assembly (photo-PISA). Macromol Rapid Commun 38:1600508.
   Web of Science ®Google Scholar
• Tenchov R, Bird R, Curtze AE, Zhou QQ. (2021). Lipid nanoparticles-from liposomes to mRNA vaccine delivery, a landscape of research diversity and advancement. ACS Nano 15:16982–7015.
   PubMed Web of Science ®Google Scholar
• Thambi T, Park JH, Lee DS. (2016). Stimuli-responsive polymersomes for cancer therapy. Biomater Sci 4:55–69.
   PubMed Web of Science ®Google Scholar
• Tian XY, Ding JJ, Zhang B, Qiu F, Zhuang XD, Chen Y. (2018). Recent advances in RAFT polymerization: novel initiation mechanisms and optoelectronic applications. Polymers 10:318.
   PubMed Web of Science ®Google Scholar
• Wang XR, Hu JM, Liu GH, Tian J, Wang HJ, Gong M, Liu SY. (2015). Reversibly switching bilayer permeability and release modules of photochromic polymersomes stabilized by cooperative noncovalent interactions. J Am Chem Soc 137:15262–75.
   PubMed Web of Science ®Google Scholar
• Warren NJ, Armes SP. (2014). Polymerization-induced self-assembly of block copolymer nanoobjects via RAFT aqueous dispersion polymerization. J Am Chem Soc 136:10174–85.
   PubMed Web of Science ®Google Scholar
• Xu XF, Pan CY, Zhang WJ, Hong CY. (2019). Polymerization-induced self-assembly generating vesicles with adjustable pH-responsive release performance. Macromolecules 52:1965–75.
   Web of Science ®Google Scholar
• Yao CZ, Li YM, Wang ZX, Song CZ, Hu XL, Liu SY. (2020). Cytosolic NQO1 enzyme-activated near-infrared fluorescence imaging and photodynamic therapy with polymeric vesicles. ACS Nano 14:1919–35.
   PubMed Web of Science ®Google Scholar
• Yu SY, Azzam T, Rouiller I, Eisenberg A. (2009). “Breathing” vesicles. J Am Chem Soc 131:10557–66.
   PubMed Web of Science ®Google Scholar
• Yu WQ, Liu R, Zhou Y, Gao HL. (2020). Size-tunable strategies for a tumor targeted drug delivery system. ACS Cent Sci 6:100–16.
   PubMed Web of Science ®Google Scholar
• Zhang WJ, Hong CY, Pan CY. (2016). Fabrication of reductive-responsive prodrug nanoparticles with superior structural stability by polymerization-induced self-assembly and functional nanoscopic platform for drug delivery. Biomacromolecules 17:2992–9.
   PubMed Web of Science ®Google Scholar
• Zhang WJ, Hong CY, Pan CY. (2017). Artificially smart vesicles with superior structural stability: fabrication, characterizations, and transmembrane traffic. ACS Appl Mater Interfaces 9:15086–95.
   PubMed Web of Science ®Google Scholar
• Zhang WJ, Hong CY, Pan CY. (2017). Efficient fabrication of photosensitive polymeric nano-objects via an ingenious formulation of RAFT dispersion polymerization and their application for drug delivery. Biomacromolecules 18:1210–7.
   PubMed Web of Science ®Google Scholar
• Zhang F, Niu YL, Li YT, Yao Q, Chen XQ, Zhou HJ, Zhou MM, Xiao JJ. (2021). Fabrication and characterization of structurally stable pH-responsive polymeric vesicles by polymerization-induced self-assembly. RSC Adv 11:29042–51.
   PubMed Web of Science ®Google Scholar
• Zhao M, Ma W, Ma CN. (2020). Circ_0067934 promotes non-small cell lung cancer development by regulating miR-1182/KLF8 axis and activating Wnt/β-catenin pathway. Biomed Pharmacother 129:110461.
   PubMed Web of Science ®Google Scholar
• Zhu HS, Geng QR, Chen WQ, Zhu YQ, Chen J, Du JZ. (2013). Antibacterial high-genus polymer vesicle as an “armed” drug carrier. J Mater Chem B 1:5496–504.
   PubMed Web of Science ®Google Scholar
• Zhu AQ, Lv XQ, Shen LL, Zhang BH, An ZS. (2017). Polymerization-induced cooperative assembly of block copolymer and homopolymer via RAFT dispersion polymerization. ACS Macro Lett 6:304–9.
   PubMed Web of Science ®Google Scholar
• Zhuang XB, Qiao TK, Xu GX, Yuan SJ, Zhang Q, Chen X. (2016). Combination of nadroparin with radiotherapy results in powerful synergistic antitumor effects in lung adenocarcinoma A549 cells. Oncol Rep 36:2200–6.
   PubMed Web of Science ®Google Scholar