2,806
Views
5
CrossRef citations to date
0
Altmetric
Research Article

Formulation and evaluation of Piroxicam nanosponge for improved internal solubility and analgesic activity

, , , , , , & show all
Article: 2174208 | Received 08 Dec 2022, Accepted 24 Jan 2023, Published online: 06 Feb 2023

References

  • Adams W, Yehur S, Woods L, Mitchell C. (1969). Drug interaction as a factor in the development of tolerance to the analgesic effect of morphine. J Pharm Exp Ther 168:1–10.
  • Amberkar M, Tara S, Meena K, Smita S. (2011). Evaluation of anti-inflammatory and analgesic activities of alcoholic extract of kaempferia galangal in rats. Indian J Physiol Pharmacol 55:13–24.
  • Amidon GL, Lennernas H, Shah VP, Crison JR. (1995). A theoretical basis for a biopharmaceutic drug classification: the correlation of in vitro drug product dissolution and in vivo bioavailability. Pharm Res 12:413–20.
  • Ansari KA, Vavia PR, Trotta F, Cavalli R. (2011). Cyclodextrin-based nanosponges for delivery of resveratrol: in vitro characterisation, stability, cytotoxicity and permeation study. AAPS PharmSciTech 12:279–86.
  • Attia IA, El-Gizawy SA, Fouda MA, Donia AM. (2007). Influence of a niosomal formulation on the oral bioavailability of Acyclovir in rabbits. AAPS PharmSciTech 8:206–12.
  • Bencini M, Ranucci E, Ferruti P, et al. (2008). Preparation and in vitro evaluation of the antiviral activity of the Acyclovir complex of a beta-cyclodextrin/poly(amidoamine) copolymer. J Control Release 126:17–25.
  • Bertino Ghera B, Perret F, Chevalier Y, Parrot-Lopez H. (2009). Novel nanoparticles made from amphiphilic perfluoroalkyl_-cyclodextrin derivatives: preparation, characterization and application to the transport of Acyclovir. Int J Pharm 375:155–62.
  • Bolton S, Bon C. 2004. Pharmaceutical statistics and practical and clinical applications. 4th ed., Rev. and Expanded ed. New York: Marcel Dekker Inc., 96–146.
  • Burcea-Dragomiroiu G, Cimpoiesu A, Ginghina O, et al. (2015). The development and validation of a rapid HPLC method for determination of piroxicam. Farmacia 63:123–31.
  • Cavalli R, Trotta F, Tumiatti W. (2006). Cyclodextrin-based nanosponges for drug delivery. J Incl Phenom Macrocycl Chem 56:209–13.
  • Deng J, Huang L, Liu F. (2010). Understanding the structure and stability of paclitaxel nanocrystals. Int J Pharm 390:242–9.
  • Diehl KH, Hull R, Morton D, European Federation of Pharmaceutical Industries Association and European Centre for the Validation of Alternative Methods, et al. (2001). A good practice guide to the administration of substances and removal of blood, including routes and volumes. J Appl Toxicol 21:15–23.
  • Dubes A, Degobert G, Fessi H, Parrot-Lopez H. (2003). Synthesis and characterization of sulfated amphiphilic α-, β-, γ and cyclodextrins: application to the complexation of Acyclovir. Carbohydr Res 338:2185–93.
  • Gaber DA, Alhuwaymili AS, Alhawas HS, et al. (2022a). Synthesized nano particles of glimepiride via spray freezing into cryogenic liquid: characterization, antidiabetic activity, and bioavailability. Drug Deliv 29:364–73.
  • Gaber DA, Alnwiser MA, Alotaibi NL, et al. (2022b). Design and optimization of ganciclovir solid dispersion for improving its bioavailability. Drug Deliv 29:1836–47.
  • Gangadharappa HV, Chandra Prasad SM, Singh RP. (2017). Formulation, in vitro and in vivo evaluation of celecoxib nanosponge hydrogels for topical application. J Drug Deliv Sci Technol 41:488–501.
  • Haroon R, AbdulSadiq SK, Khan MA, et al. (2017). Aceclofenac nanocrystals with enhanced in vitro, in vivo performance: formulation optimization, characterization, analgesic and acute toxicity studies. Drug Des Devel Ther 11:2443–52.
  • Higuchi T. (1963). Mechanism of sustained action medication: theoretical analysis of rate of release of solid drugs dispersed in solid matrices. J Pharm Sci 52:1145–9.
  • Huang Z, Liu S, Fang G, Zhang B. (2013). Synthesis and swelling properties of bcyclodextrin-based superabsorbent resin with network structure. Carbohydr Polym 92:2314–20.
  • ICH Harmonized Tripartite Guidelines. (2003). Stability testing of new drug substances and products. ICH Q1A (R2). Fed Regist 68:65717–e65718.
  • Kawabata Y, Wada K, Nakatani M, et al. (2011). Formulation design for poorly watersoluble drugs based on biopharmaceutics classification system: basic approaches and practical applications. Int J Pharm 420:1–10.,
  • Khalid A, Ansari PR, Vavia FT, Cavalli R. (2011). Cyclodextrin-based nanosponges for delivery of resveratrol: in vitro characterisation, stability, cytotoxicity and permeation study. AAPS PharmSciTech 12:111–123.
  • Kumar S, Narasimhan B, Lim SM, et al. (2019). Design, synthesis and biological potential of 5-(2-amino-6-(3/4-bromophenyl)pyrimidin-4-yl)benzene-1,3-diol scaffolds as promising antimicrobial and anticancer agents. Mini Rev Med Chem 19:851–64.
  • Mani V, Arfeen M, Ali HM, et al. (2021). Neuroprotective effect of clobenpropit against lipopolysaccharide-induced cognitive deficits via attenuating neuroinflammation and enhancing mitochondrial functions in mice. Brain Sci 11:1617.
  • Merisko-Liversidge E, Liversidge GG, Cooper ER. (2003). Nanosizing: a formulation approach for poorly-water-soluble compounds. Eur J Pharm Sci 18:113–20.
  • Ming-Wei J, Cheng-Gong G, Liang W, et al. (2013). Studies on the orthogonal assembly of b-cyclodextrin-poly (epsilon-caprolactone) and ferrocene-poly (ethylene oxide. Carbohydr Polym 92:1566–72.
  • Mognetti B, Barberis A, Marino S, et al. (2012). In vitro enhancement of anticancer activity of paclitaxel by a Cremophor free cyclodextrin-based nanosponge formulation. J Incl Phenom Macrocycl Chem 74:201–10.
  • Patel TB, Patel LD. (2012). Formulation and development strategies for drugs insoluble in gastric fluid. Int Res J Pharm 3:106–13.
  • Prabhu S, Ortega M, Ma C. (2005). Novel lipid-based formulations enhancing the in vitro dissolution and permeability characteristics of a poorly water–soluble model drug, piroxicam. Int J Pharm 301:209–16.
  • Pushpalatha R, Selvamuthukumar S, Kilimozhi D. (2018). Cross-linked, cyclodextrin-based nanosponges for curcumin delivery - Physicochemical characterization, drug release, stability and cytotoxicity. J Drug Delivery Sci Technol 45:45–53.
  • Rao M, Bajaj A, Khole I, et al. (2013). In vitro and in vivo evaluation of b-cyclodextrin-based nanosponges of telmisartan. J Incl Phenom Macrocycl Chem 77:135–45.
  • Serajuddin ATM. (2007). Salt formation to improve solubility. Advan. Drug Delivery Rev 59:603–16.
  • Shah SMH, Ullah F, Khan S, et al. (2016). Smart nanocrystals of artemether: fabrication, characterization, and comparative in vitro and in vivo antimalarial evaluation. Drug Des Devel Ther 10:3837–50.
  • Shikov AN, Pozharitskaya ON, Miroshnyk I, et al. (2009). Nanodispersions of taxifolin: impact of solid-state properties on dissolution behavior. Int J Pharm 377:148–52.
  • Shringirishi M, Mahor A, Gupta R, et al. (2017). Fabrication and characterization of nifedipine loaded b-cyclodextrin nanosponges: an in vitro and in vivo evaluation. J Drug Deliv Sci Technol 41:344–50.
  • Suresh G, Manjunath K, Venkateswarlu V, Satyanarayana V. (2007). Preparation, characterization, and in vitro and in vivo evaluation of lovastatin solid lipid nanoparticles. AAPS PharmSciTech 8:E162–E170.
  • Swaminathan S, Vavia P, Trotta F, Torne S. (2007). Formulation of cyclodextrinbased nanosponges of itraconazole. J Incl Phenom Macrocycl Chem 57:89–94.
  • Swaminathan S, Vavia PR, Trotta F, Cavalli R. (2013). Nanosponges encapsulating dexamethasone for ocular delivery: formulation design, physicochemical characterization, safety and corneal permeability assessment. J Biomed Nanotechnol 9:998–1007.
  • Torne S, Darandale S, Vavia P, et al. (2013). Cyclodextrin-based nanosponges: effective nanocarrier for tamoxifen delivery. Pharm Dev Technol 18:619–25.
  • Trotta F, Zanetti M, Cavalli R. (2012). Cyclodextrin-based nanosponges as drug carriers. Beilstein J Org Chem 8:2091–9.
  • Wu K, Li J, Wang W, Winstead DA. (2009). Formation and characterization of solid dispersions of piroxicam and polyvinylpyrrolidone using spray drying and precipitation with compressed antisolvent. J Pharm Sci 98:2422–31.