REFERENCES
- Karavitis, M., Fronticelli, C., Brinigar, W.S., Vasquez, G.B., Militello, V., Leone, M., Cupane, A. (1998). Properties of human hemoglobin with increased polarity in the α or β heme pocket. Carbonmonoxy derivatives. J. Biol. Chem. 237: 23740–23749.
- Fronticelli, C., Bellelli, A., Brinigar, W.S. (2004). Approaches to the engineering of hemoglobin-based oxygen carriers. Trans. Alt. in Trans. Med. 5: 516–520.
- Bobofchak, K.M., Mito, T., Texel, S.J., Bellelli, A., Nemoto, M., Traystman, R.J., Koehler, R.C., Brinigar, W.S., Fronticelli, C. (2003). A recombinant polymeric hemoglobin with the conformational, functional, and physiological characteristics of an in vivo O2 transporter. Am. J. Physiol. Heart Circ. Physiol. 285: H549–H561.
- Fronticelli, C., Sanna, M.T., Perez-Alvarado, G.C., Karavitis, M., Lu, A.-L., Brinigar, W.S. (1995). Allosteric modulation by tertiary structure in mammalian hemoglobins. Introduction of the functional characteristics of bovine hemoglobin into human hemoglobin by five amino acid substitutions. J. Biol. Chem. 270: 30588–30592.
- Fronticelli, C., Bobofchak, K.M., Karavitis, M., Sanna, M.T., Brinigar, W.S. (2002). Introduction of a new regulatory mechanism into human hemoglobin. Biophys. Chem. 98: 115–126.
- Doherty, D.H., Doyle, M.P., Curry, S.R., Vali, R.J., Fattor, T.J., Olson, J.S., Lemon, D.D. (1998). Rate of reaction with nitric oxide determines the hypertensive effect of cell-free hemoglobin. Nat. Biotechnol. 16: 672–676.
- Sakai, H., Hara, H., Yuasa, M., Tsai,A.G., Takeoka, S., Tsuchida, E., Intaglietta, M. (2000). Molecular dimensions of Hb-based O2 carriers determine constriction of resistance arteries and hypertension. Am. J. Physiol. (Heart Circ. Physiol.) 279: H908–H915.
- Matheson, B., Kwansa, H.E., Bucci, E., Rebel, A., Koehler, R.C. (2002). Vascular response to infusion of non extravasating hemoglobin polymer. J. Appl. Physiol. 93: 1479–1486.
- Fronticelli, C., Arosio, D., Bobofchak, K.M., Vasquez, G.B. (2001). Molecular engineering of a polymer of tetrameric hemoglobins. Proteins 44: 212–222.
- Hughes, G.S., Antal, E.J., Locker, P.K., Francom, S.F., Adams, W.J., Jacobs, E.E. (1996). Physiology and pharmacokinetics of a novel hemoglobin-based oxygen carrier in humans. Crit. Care. Med. 24: 756–764.
- Hughes, G.S., Francom, S.F., Antal, E.J., Adams, W.J., Locker, P.K., Yancey, E.P., Jacobs, E.E. (1995). Hematologic effects of a novel hemoglobin-based oxygen carrier in normal male and female subjects. J. Lab. Clin. Med. 126: 444–451.