7
Views
1
CrossRef citations to date
0
Altmetric
Articles

Ca2+ Channels and Chronic Hypoxia

, &
Pages 657-670 | Received 29 Mar 2006, Accepted 19 May 2006, Published online: 10 Jul 2009

REFERENCES

  • Alfranca A, Gutierrez M D, Vara A, Aragones J, Vidal F, Landazuri M O. c-Jun and hypoxia-inducible factor 1 functionally cooperate in hypoxia-induced gene transcription. Mol Cell Biol 2002; 22: 12–22, [INFOTRIEVE], [CSA]
  • Altura B M, Kostellow A B, Zhang A, Li W, Morrill G A, Gupta R K, Altura B T. Expression of the nuclear factor-kappaB and proto-oncogenes c-fos and c-jun are induced by low extracellular Mg2+ in aortic and cerebral vascular smooth muscle cells: possible links to hypertension, atherogenesis, and stroke. Am J Hypertens 2003; 16: 701–707, [INFOTRIEVE], [CSA], [CROSSREF]
  • Amenta F, Bisetti A, Bronzetti E, Coppola L, Felici L, Ferrante F, Mariotta S, Ricci A. Density and localization of calcium channels of the L-type in human pulmonary artery. Clin Exp Hypertens 1998; 20: 389–402, [INFOTRIEVE], [CSA]
  • Aromolaran A A, Blatter L A. Modulation of intracellular Ca2+ release and capacitative Ca2+ entry by CaMKII inhibitors in bovine vascular endothelial cells. Am J Physiol Cell Physiol 2005; 289: C1426–1436, [INFOTRIEVE], [CSA], [CROSSREF]
  • Bakhramov A, Evans A M, Kozlowski R Z. Differential effects of hypoxia on the intracellular Ca2+ concentration of myocytes isolated from different regions of the rat pulmonary arterial tree. Exp Physiol 1998; 83: 337–347, [INFOTRIEVE], [CSA]
  • Barbera J A, Roger N, Roca J, Rovira I, Higenbottam T W, Rodriguez-Roisin R. Worsening of pulmonary gas exchange with nitric oxide inhalation in chronic obstructive pulmonary disease. Lancet 1996; 347: 436–440, [INFOTRIEVE], [CSA], [CROSSREF]
  • Blaustein M P, Lederer W J. Sodium/calcium exchange: its physiological implications. Physiol Rev 1999; 79: 763–854, [INFOTRIEVE], [CSA]
  • Boittin F X, Macrez N, Halet G, Mironneau J. Norepinephrine-induced Ca2+ waves depend on InsP3 and ryanodine receptor activation in vascular myocytes. Am J Physiol 1999; 277: C139–C151, [INFOTRIEVE], [CSA]
  • Bonnet S, Belus A, Hyvelin J M, Roux E, Marthan R, Savineau J P. Effect of chronic hypoxia on agonist-induced tone and calcium signaling in rat pulmonary artery. Am J Physiol Lung Cell Mol Physiol 2001; 281: L193–L201, [INFOTRIEVE], [CSA]
  • Bonnet S, Hyvelin J M, Bonnet P, Marthan R, Savineau J P. Chronic hypoxia-induced spontaneous and rhythmic contractions in the rat main pulmonary artery. Am J Physiol Lung Cell Mol Physiol 2001; 281: L183–L192, [INFOTRIEVE], [CSA]
  • Bourinet E, Mangoni M E, Nargeot J. Dissecting the functional role of different isoforms of the L-type Ca2+ channel. J Clin Invest 2004; 113: 1382–1384, [INFOTRIEVE], [CSA], [CROSSREF]
  • Brough G H, Wu S, Cioffi D, Moore T M, Li M, Dean N, Stevens T. Contribution of endogenously expressed Trp1 to a Ca2+-selective, store-operated Ca2+ entry pathway. FASEB J 2001; 15: 1727–1738, [INFOTRIEVE], [CSA], [CROSSREF]
  • Brown S E, Linden G S, King R R, Blair G P, Stansbury D W, Light R W. Effects of verapamil on pulmonary haemodynamics during hypoxaemia, at rest, and during exercise in patients with chronic obstructive pulmonary disease. Thorax 1983; 38: 840–844, [INFOTRIEVE], [CSA]
  • Buckley B J, Mirza Z, Whorton A R. Regulation of Ca2+-dependent nitric oxide synthase in bovine aortic endothelial cells. Am J Physiol 1995; 269: C757–C765, [INFOTRIEVE], [CSA]
  • Busse R, Mulsch A. Calcium-dependent nitric oxide synthesis in endothelial cytosol is mediated by calmodulin. FEBS Lett 1990; 265: 133–136, [INFOTRIEVE], [CSA], [CROSSREF]
  • Catterall W A. Structure and regulation of voltage-gated Ca2+ channels. Annu Rev Cell Dev Biol 2000; 16: 521–555, [INFOTRIEVE], [CSA], [CROSSREF]
  • Chetham P M, Babal P, Bridges J P, Moore T M, Stevens T. Segmental regulation of pulmonary vascular permeability by store-operated Ca2+ entry. Am J Physiol 1999; 276: L41–L50, [INFOTRIEVE], [CSA]
  • Cioffi D L, Wu S, Stevens T. On the endothelial cell ISOC. Cell Calcium 2003; 33: 323–336, [INFOTRIEVE], [CSA], [CROSSREF]
  • Cornfield D N, Stevens T, McMurtry I F, Abman S H, Rodman D M. Acute hypoxia causes membrane depolarization and calcium influx in fetal pulmonary artery smooth muscle cells. Am J Physiol 1994; 266: L469–L475, [INFOTRIEVE], [CSA]
  • Corsini A, Bonfatti M, Quarato P, Accomazzo M R, Raiteri M, Sartani A, Testa R, Nicosia S, Paoletti R, Fumagalli R. Effect of the new calcium antagonist lercanidipine and its enantiomers on the migration and proliferation of arterial myocytes. J Cardiovasc Pharmacol 1996; 28: 687–694, [INFOTRIEVE], [CSA], [CROSSREF]
  • Davies P, Maddalo F, Reid L. Effects of chronic hypoxia on structure and reactivity of rat lung microvessels. J Appl Physiol 1985; 58: 795–801, [INFOTRIEVE], [CSA]
  • Dawson C A, Grimm D J, Linehan J H. Influence of hypoxia on the longitudinal distribution of pulmonary vascular resistance. J Appl Physiol 1978; 44: 493–498, [INFOTRIEVE], [CSA]
  • Dipp M, Nye P C, Evans A M. Hypoxic release of calcium from the sarcoplasmic reticulum of pulmonary artery smooth muscle. Am J Physiol Lung Cell Mol Physiol 2001; 281: L318–L325, [INFOTRIEVE], [CSA]
  • Emori T, Hirata Y, Ohta K, Shichiri M, Marumo F. Secretory mechanism of immunoreactive endothelin in cultured bovine endothelial cells. Biochem Biophys Res Commun 1989; 160: 93–100, [INFOTRIEVE], [CSA], [CROSSREF]
  • Fagan K A, Oka M, Bauer N R, Gebb S A, Ivy D D, Morris K G, McMurtry I F. Attenuation of acute hypoxic pulmonary vasoconstriction and hypoxic pulmonary hypertension in mice by inhibition of Rho-kinase. Am J Physiol Lung Cell Mol Physiol 2004; 287: L656–L664, [INFOTRIEVE], [CSA], [CROSSREF]
  • Fan Q I, Vanderpool K, Marsh J D. A 27 bp cis-acting sequence is essential for L-type calcium channel alpha(1C) subunit expression in vascular smooth muscle cells. Biochim Biophys Acta 2002; 1577: 401–411, [INFOTRIEVE], [CSA]
  • Fantozzi I, Zhang S, Platoshyn O, Remillard C V, Cowling R T, Yuan J X. Hypoxia increases AP-1 binding activity by enhancing capacitative Ca2+ entry in human pulmonary artery endothelial cells. Am J Physiol Lung Cell Mol Physiol 2003; 285: L1233–L1245, [INFOTRIEVE], [CSA]
  • Farrukh I S, Michael J R. Cellular mechanisms that control pulmonary vascular tone during hypoxia and normoxia: possible role of Ca2+ATPases. Am Rev Respir Dis 1992; 145: 1389–1397, [INFOTRIEVE], [CSA]
  • Fike C D, Kaplowitz M R. Nifedipine inhibits pulmonary hypertension but does not prevent decreased lung eNOS in hypoxic newborn pigs. Am J Physiol 1999; 277: L449–L456, [INFOTRIEVE], [CSA]
  • Fisher A B, Al-Mehdi A B, Manevich Y. Shear stress and endothelial cell activation. Crit Care Med 2002; 30: S192–S197, [INFOTRIEVE], [CSA], [CROSSREF]
  • Fishman A P. Hypoxia on the pulmonary circulation: how and where it acts. Circ Res 1976; 38: 221–231, [INFOTRIEVE], [CSA]
  • Flynn E R, Bradley K N, Muir T C, McCarron J G. Functionally separate intracellular Ca2+ stores in smooth muscle. J Biol Chem 2001; 276: 36411–36418, [INFOTRIEVE], [CSA], [CROSSREF]
  • Freay A, Johns A, Adams D J, Ryan U S, Van Breemen C. Bradykinin and inositol 1,4,5-trisphosphate-stimulated calcium release from intracellular stores in cultured bovine endothelial cells. Pflugers Arch 1989; 414: 377–384, [INFOTRIEVE], [CSA], [CROSSREF]
  • Ginty D D, Glowacka D, Bader D S, Hidaka H, Wagner J A. Induction of immediate early genes by Ca2+ influx requires cAMP-dependent protein kinase in PC12 cells. J Biol Chem 1991; 266: 17454–17458, [INFOTRIEVE], [CSA]
  • Golovina V A, Platoshyn O, Bailey C L, Wang J, Limsuwan A, Sweeney M, Rubin L J, Yuan J X. Upregulated TRP and enhanced capacitative Ca2+ entry in human pulmonary artery myocytes during proliferation. Am J Physiol Heart Circ Physiol 2001; 280: H746–H755, [INFOTRIEVE], [CSA]
  • Hales C A, Kradin R L, Brandstetter R D, Zhu Y J. Impairment of hypoxic pulmonary artery remodeling by heparin in mice. Am Rev Respir Dis 1983; 128: 747–751, [INFOTRIEVE], [CSA]
  • Hampl V, Cornfield D N, Cowan N J, Archer S L. Hypoxia potentiates nitric oxide synthesis and transiently increases cytosolic calcium levels in pulmonary artery endothelial cells. Eur Respir J 1995; 8: 515–522, [INFOTRIEVE], [CSA]
  • Harder D R, Madden J A, Dawson C. Hypoxic induction of Ca2+-dependent action potentials in small pulmonary arteries of the cat. J Appl Physiol 1985; 59: 1389–1393, [INFOTRIEVE], [CSA]
  • Hardingham G E, Cruzalegui F H, Chawla S, Bading H. Mechanisms controlling gene expression by nuclear calcium signals. Cell Calcium 1998; 23: 131–134, [INFOTRIEVE], [CSA], [CROSSREF]
  • Hisatsune C, Kuroda Y, Nakamura K, Inoue T, Nakamura T, Michikawa T, Mizutani A, Mikoshiba K. Regulation of TRPC6 channel activity by tyrosine phosphorylation. J Biol Chem 2004; 279: 18887–18894, [INFOTRIEVE], [CSA], [CROSSREF]
  • Hong Z, Weir E K, Nelson D P, Olschewski A. Subacute hypoxia decreases voltage-activated potassium channel expression and function in pulmonary artery myocytes. Am J Respir Cell Mol Biol 2004; 31: 337–343, [INFOTRIEVE], [CSA], [CROSSREF]
  • Hoshino Y, Obara H, Kusunoki M, Fujii Y, Iwai S. Hypoxic contractile response in isolated human pulmonary artery: role of calcium ion. J Appl Physiol 1988; 65: 2468–2474, [INFOTRIEVE], [CSA]
  • Howell K, Preston R J, McLoughlin P. Chronic hypoxia causes angiogenesis in addition to remodelling in the adult rat pulmonary circulation. J Physiol 2003; 547: 133–145, [INFOTRIEVE], [CSA], [CROSSREF]
  • Inoue R, Okada T, Onoue H, Hara Y, Shimizu S, Naitoh S, Ito Y, Mori Y. The transient receptor potential protein homologue TRP6 is the essential component of vascular α(1)-adrenoceptor-activated Ca2+-permeable cation channel. Circ Res 2001; 88: 325–332, [INFOTRIEVE], [CSA]
  • Jabr R I, Toland H, Gelband C H, Wang X X, Hume J R. Prominent role of intracellular Ca2+ release in hypoxic vasoconstriction of canine pulmonary artery. Br J Pharmacol 1997; 122: 21–30, [INFOTRIEVE], [CSA], [CROSSREF]
  • Janiak R, Wilson S M, Montague S, Hume J R. Heterogeneity of calcium stores and elementary release events in canine pulmonary arterial smooth muscle cells. Am J Physiol Cell Physiol 2001; 280: 22–33, [CSA]
  • Jernigan N L, Broughton B R, Walker B R, Resta T C. Impaired NO-dependent inhibition of store- and receptor-operated calcium entry in pulmonary vascular smooth muscle following after chronic hypoxia. Am J Physiol Lung Cell Mol Physiol 2006; 290: L517–L525, [INFOTRIEVE], [CSA], [CROSSREF]
  • Kang T M, Park M K, Uhm D Y. Characterization of hypoxia-induced [Ca2+]i rise in rabbit pulmonary arterial smooth muscle cells. Life Sci 2002; 70: 2321–2333, [INFOTRIEVE], [CSA], [CROSSREF]
  • Kennedy T P, Michael J R, Summer W. Calcium channel blockers in hypoxic pulmonary hypertension. Am J Med 1985; 78: 18–26, [INFOTRIEVE], [CSA], [CROSSREF]
  • Khachigian L M, Fries J W, Benz M W, Bonthron D T, Collins T. Novel cis-acting elements in the human platelet-derived growth factor B-chain core promoter that mediate gene expression in cultured vascular endothelial cells. J Biol Chem 1994; 269: 22647–22656, [INFOTRIEVE], [CSA]
  • Kohno M, Yokokawa K, Horio T, Yasunari K, Murakawa K, Ikeda M, Takeda T. Release mechanism of endothelin-1 and big endothelin-1 after stimulation with thrombin in cultured porcine endothelial cells. J Vasc Res 1992; 29: 56–63, [INFOTRIEVE], [CSA]
  • Kruse H J, Bauriedel G, Heimerl J, Hofling B, Weber P C. Role of L-type calcium channels on stimulated calcium influx and on proliferative activity of human coronary smooth muscle cells. J Cardiovasc Pharmacol 1994; 24: 328–335, [INFOTRIEVE], [CSA]
  • Kuga T, Sadoshima J, Tomoike H, Kanaide H, Akaike N, Nakamura M. Actions of Ca2+ antagonists on two types of Ca2+ channels in rat aorta smooth muscle cells in primary culture. Circ Res 1990; 67: 469–480, [INFOTRIEVE], [CSA]
  • Kunichika N, Yu Y, Remillard C V, Platoshyn O, Zhang S, Yuan J X. Overexpression of TRPC1 enhances pulmonary vasoconstriction induced by capacitative Ca2+ entry. Am J Physiol Lung Cell Mol Physiol 2004; 287: L962–L969, [INFOTRIEVE], [CSA], [CROSSREF]
  • Laporte R, Hui A, Laher I. Pharmacological modulation of sarcoplasmic reticulum function in smooth muscle. Pharmacol Rev 2004; 56: 439–513, [INFOTRIEVE], [CSA], [CROSSREF]
  • Lee M E, Dhadly M S, Temizer D H, Clifford J A, Yoshizumi M, Quertermous T. Regulation of endothelin-1 gene expression by Fos and Jun. J Biol Chem 1991; 266: 19034–19039, [INFOTRIEVE], [CSA]
  • Lin M J, Leung G P, Zhang W M, Yang X R, Yip K P, Tse C M, Sham J S. Chronic hypoxia-induced upregulation of store-operated and receptor-operated Ca2+ channels in pulmonary arterial smooth muscle cells: a novel mechanism of hypoxic pulmonary hypertension. Circ Res 2004; 95: 496–505, [INFOTRIEVE], [CSA], [CROSSREF]
  • Low A M, Sormaz L, Kwan C Y, Daniel E E. Mobilization of internal Ca2+ by vasoactive intestinal polypeptide in endothelial cells. Eur J Pharmacol 1997; 339: 227–235, [INFOTRIEVE], [CSA], [CROSSREF]
  • Madden J A, Dawson C A, Harder D R. Hypoxia-induced activation in small isolated pulmonary arteries from the cat. J Appl Physiol 1985; 59: 113–118, [INFOTRIEVE], [CSA]
  • Madden J A, Vadula M S, Kurup V P. Effects of hypoxia and other vasoactive agents on pulmonary and cerebral artery smooth muscle cells. Am J Physiol 1992; 263: L384–L393, [INFOTRIEVE], [CSA]
  • Magnier-Gaubil C, Herbert J M, Quarck R, Papp B, Corvazier E, Wuytack F, Levy-Toledano S, Enouf J. Smooth muscle cell cycle and proliferation. Relationship between calcium influx and sarco-endoplasmic reticulum Ca2+ATPase regulation. J Biol Chem 1996; 271: 27788–27794, [INFOTRIEVE], [CSA], [CROSSREF]
  • Marin J, Encabo A, Briones A, Garcia-Cohen E C, Alonso M J. Mechanisms involved in the cellular calcium homeostasis in vascular smooth muscle: calcium pumps. Life Sci 1999; 64: 279–303, [INFOTRIEVE], [CSA], [CROSSREF]
  • Martin T W, Michaelis K C. Ca2+-dependent synthesis of prostaglandin I2 and mobilization of arachidonic acid from phospholipids in cultured endothelial cells permeabilized with saponin. Biochim Biophys Acta 1990; 1054: 159–168, [INFOTRIEVE], [CSA], [CROSSREF]
  • McCulloch K M, Docherty C, MacLean M R. Endothelin receptors mediating contraction of rat and human pulmonary resistance arteries: effect of chronic hypoxia in the rat. Br J Pharmacol 1998; 123: 1621–1630, [INFOTRIEVE], [CSA], [CROSSREF]
  • McDaniel S S, Platoshyn O, Wang J, Yu Y, Sweeney M, Krick S, Rubin L J, Yuan J X. Capacitative Ca2+ entry in agonist-induced pulmonary vasoconstriction. Am J Physiol Lung Cell Mol Physiol 2001; 280: L870–L880, [INFOTRIEVE], [CSA]
  • McMurtry I F, Davidson A B, Reeves J T, Grover R F. Inhibition of hypoxic pulmonary vasoconstriction by calcium antagonists in isolated rat lungs. Circ Res 1976; 38: 99–104, [INFOTRIEVE], [CSA]
  • Mehta D, Malik A B. Signaling mechanisms regulating endothelial permeability. Physiol Rev 2006; 86: 279–367, [INFOTRIEVE], [CSA], [CROSSREF]
  • Meyrick B, Reid L. The effect of continued hypoxia on rat pulmonary arterial circulation: an ultrastructural study. Lab Invest 1978; 38: 188–200, [INFOTRIEVE], [CSA]
  • Michael J R, Kennedy T P, Buescher P, Farrukh I, Lodato R, Rock P C, Gottlieb J, Gurtner G, de la Monte S M, Hutchins G M. Nitrendipine attenuates the pulmonary vascular remodeling and right ventricular hypertrophy caused by intermittent hypoxia in rats. Am Rev Respir Dis 1986; 133: 375–379, [INFOTRIEVE], [CSA]
  • Mishra S K, Hermsmeyer K. Selective inhibition of T-type Ca2+ channels by Ro 40-5967. Circ Res 1994; 75: 144–148, [INFOTRIEVE], [CSA]
  • Mogami H, Kojima I. Stimulation of calcium entry is prerequisite for DNA synthesis induced by platelet-derived growth factor in vascular smooth muscle cells. Biochem Biophys Res Commun 1993; 196: 650–658, [INFOTRIEVE], [CSA], [CROSSREF]
  • Moinard J, Manier G, Pillet O, Castaing Y. Effect of inhaled nitric oxide on hemodynamics and VA/Q inequalities in patients with chronic obstructive pulmonary disease. Am J Respir Crit Care Med 1994; 149: 1482–1487, [INFOTRIEVE], [CSA]
  • Moore T M, Brough G H, Babal P, Kelly J J, Li M, Stevens T. Store-operated calcium entry promotes shape change in pulmonary endothelial cells expressing Trp1. Am J Physiol 1998; 275: L574–L582, [INFOTRIEVE], [CSA]
  • Muramatsu M, Tyler R C, Rodman D M, McMurtry I F. Possible role of T-type Ca2+ channels in L-NNA vasoconstriction of hypertensive rat lungs. Am J Physiol 1997; 272: H2616–H2621, [INFOTRIEVE], [CSA]
  • Nagaoka T, Morio Y, Casanova N, Bauer N, Gebb S, McMurtry I, Oka M. Rho/Rho kinase signaling mediates increased basal pulmonary vascular tone in chronically hypoxic rats. Am J Physiol Lung Cell Mol Physiol 2004; 287: L665–L672, [INFOTRIEVE], [CSA], [CROSSREF]
  • Nagasaka Y, Bhattacharya J, Nanjo S, Gropper M A, Staub N C. Micropuncture measurement of lung microvascular pressure profile during hypoxia in cats. Circ Res 1984; 54: 90–95, [INFOTRIEVE], [CSA]
  • Ng L C, Gurney A M. Store-operated channels mediate Ca2+ influx and contraction in rat pulmonary artery. Circ Res 2001; 89: 923–929, [INFOTRIEVE], [CSA]
  • Odell A F, Scott J L, Van Helden D F. Epidermal growth factor induces tyrosine phosphorylation, membrane insertion, and activation of transient receptor potential channel 4. J Biol Chem 2005; 280: 37974–37987, [INFOTRIEVE], [CSA], [CROSSREF]
  • Oka M, Morris K G, McMurtry I F. NIP-121 is more effective than nifedipine in acutely reversing chronic pulmonary hypertension. J Appl Physiol 1993; 75: 1075–1080, [INFOTRIEVE], [CSA]
  • Pacaud P, Loirand G. Release of Ca2+ by noradrenaline and ATP from the same Ca2+ store sensitive to both InsP3 and Ca2+ in rat portal vein myocytes. J Physiol 1995; 484: 549–555, [INFOTRIEVE], [CSA]
  • Pauvert O, Bonnet S, Rousseau E, Marthan R, Savineau J P. Sildenafil alters calcium signaling and vascular tone in pulmonary arteries from chronically hypoxic rats. Am J Physiol Lung Cell Mol Physiol 2004; 287: L577–L583, [INFOTRIEVE], [CSA], [CROSSREF]
  • Pearse D B, Shimoda L A, Verin A D, Bogatcheva N, Moon C, Ronnett G V, Welsh L E, Becker P M. Effect of cGMP on lung microvascular endothelial barrier dysfunction following hydrogen peroxide. Endothelium 2003; 10: 309–317, [INFOTRIEVE], [CSA]
  • Platoshyn O, Yu Y, Golovina V A, McDaniel S S, Krick S, Li L, Wang J Y, Rubin L J, Yuan J X. Chronic hypoxia decreases KV channel expression and function in pulmonary artery myocytes. Am J Physiol Lung Cell Mol Physiol 2001; 280: L801–L812, [INFOTRIEVE], [CSA]
  • Pozeg Z I, Michelakis E D, McMurtry M S, Thebaud B, Wu X C, Dyck J R, Hashimoto K, Wang S, Moudgil R, Harry G, Sultanian R, Koshal A, Archer S L. In vivo gene transfer of the O2-sensitive potassium channel Kv1.5 reduces pulmonary hypertension and restores hypoxic pulmonary vasoconstriction in chronically hypoxic rats. Circulation 2003; 107: 2037–2044, [INFOTRIEVE], [CSA], [CROSSREF]
  • Pozzan T, Rizzuto R, Volpe P, Meldolesi J. Molecular and cellular physiology of intracellular calcium stores. Physiol Rev 1994; 74: 595–636, [INFOTRIEVE], [CSA]
  • Pribnow D, Muldoon L L, Fajardo M, Theodor L, Chen L Y, Magun B E. Endothelin induces transcription of fos/jun family genes: a prominent role for calcium ion. Mol Endocrinol 1992; 6: 1003–1012, [INFOTRIEVE], [CSA], [CROSSREF]
  • Putney J W, Jr. A model for receptor-regulated calcium entry. Cell Calcium 1986; 7: 1–12, [INFOTRIEVE], [CSA], [CROSSREF]
  • Putney J W, Jr. Capacitative calcium entry revisited. Cell Calcium 1990; 11: 611–624, [INFOTRIEVE], [CSA], [CROSSREF]
  • Raj U, Shimoda L. Oxygen-dependent signaling in pulmonary vascular smooth muscle. Am J Physiol Lung Cell Mol Physiol 2002; 283: L671–L677, [INFOTRIEVE], [CSA]
  • Ramsey I S, Delling M, Clapham D E. An introduction to TRP channels. Annu Rev Physiol 2006; 68: 619–647, [INFOTRIEVE], [CSA], [CROSSREF]
  • Resnik E, Herron J, Keck M, Sukovich D, Linden B, Cornfield D N. Chronic intrauterine pulmonary hypertension selectively modifies pulmonary artery smooth muscle cell gene expression. Am J Physiol Lung Cell Mol Physiol 2006; 290: L426–L433, [INFOTRIEVE], [CSA], [CROSSREF]
  • Ricci A, Bronzetti E, El-Assouad D, Felici L, Greco S, Mariotta S, Sabbatini M, Amenta F. Influence of age on L-type Ca2+ channels in the pulmonary artery and vein of spontaneously hypertensive rats. Mech Ageing Dev 2000; 120: 33–44, [INFOTRIEVE], [CSA], [CROSSREF]
  • Rodman D M, Yamaguchi T, O'Brien R F, McMurtry I F. Hypoxic contraction of isolated rat pulmonary artery. J Pharmacol Exp Ther 1989; 248: 952–959, [INFOTRIEVE], [CSA]
  • Rodman D M, Reese K, Harral J, Fouty B, Wu S, West J, Hoedt-Miller M, Tada Y, Li K X, Cool C, Fagan K, Cribbs L. Low-voltage-activated (T-type) calcium channels control proliferation of human pulmonary artery myocytes. Circ Res 2005; 96: 864–872, [INFOTRIEVE], [CSA], [CROSSREF]
  • Rothman A, Wolner B, Button D, Taylor P. Immediate-early gene expression in response to hypertrophic and proliferative stimuli in pulmonary arterial smooth muscle cells. J Biol Chem 1994; 269: 6399–6404, [INFOTRIEVE], [CSA]
  • Sage S O, van Breemen C, Cannell M B. Sodium-calcium exchange in cultured bovine pulmonary artery endothelial cells. J Physiol 1991; 440: 569–580, [INFOTRIEVE], [CSA]
  • Sajkov D, Wang T, Frith P A, Bune A J, Alpers J A, McEvoy R D. A comparison of two long-acting vasoselective calcium antagonists in pulmonary hypertension secondary to COPD. Chest 1997; 111: 1622–1630, [INFOTRIEVE], [CSA]
  • Salvaterra C G, Rubin L J, Schaeffer J, Blaustein M P. The influence of the transmembrane sodium gradient on the responses of pulmonary arteries to decreases in oxygen tension. Am Rev Respir Dis 1989; 139: 933–939, [INFOTRIEVE], [CSA]
  • Salvaterra C G, Goldman W F. Acute hypoxia increases cytosolic calcium in cultured pulmonary arterial myocytes. Am J Physiol 1993; 264: L323–L328, [INFOTRIEVE], [CSA]
  • Sampieri A, Diaz-Munoz M, Antaramian A, Vaca L. The foot structure from the type 1 ryanodine receptor is required for functional coupling to store-operated channels. J Biol Chem 2005; 280: 24804–24815, [INFOTRIEVE], [CSA], [CROSSREF]
  • Santillan G, Baldi C, Katz S, Vazquez G, Boland R. Evidence that TRPC3 is a molecular component of the 1α, 25(OH)2D3-activated capacitative calcium entry (CCE) in muscle and osteoblast cells. J Steroid Biochem Mol Biol 2004; 89–90: 291–295, [CSA], [CROSSREF]
  • Savineau J P, Gonzalez de la Fuente P, Marthan R. Cellular mechanisms of hypoxia-induced contraction in human and rat pulmonary arteries. Respir Physiol 1995; 99: 191–198, [INFOTRIEVE], [CSA]
  • Schaefer M, Plant T D, Obukhov A G, Hofmann T, Gudermann T, Schultz G. Receptor-mediated regulation of the nonselective cation channels TRPC4 and TRPC5. J Biol Chem 2000; 275: 17517–17526, [INFOTRIEVE], [CSA]
  • Sedova M, Blatter L A. Dynamic regulation of [Ca2+]i by plasma membrane Ca2+-ATPase and Na+/Ca2+ exchange during capacitative Ca2+ entry in bovine vascular endothelial cells. Cell Calcium 1999; 25: 333–343, [INFOTRIEVE], [CSA], [CROSSREF]
  • Sham J S, Crenshaw B R, Jr., Deng L H, Shimoda L A, Sylvester J T. Effects of hypoxia in porcine pulmonary arterial myocytes: roles of KV channel and endothelin-1. Am J Physiol Lung Cell Mol Physiol 2000; 279: L262–L272, [INFOTRIEVE], [CSA]
  • Shimoda L A, Sylvester J T, Sham J S. Chronic hypoxia alters effects of endothelin and angiotensin on K+ currents in pulmonary arterial myocytes. Am J Physiol 1999; 277: L431–L439, [INFOTRIEVE], [CSA]
  • Shimoda L A, Sham J S, Shimoda T H, Sylvester J T. L-type Ca2+ channels, resting [Ca2+]i, and ET-1-induced responses in chronically hypoxic pulmonary myocytes. Am J Physiol Lung Cell Mol Physiol 2000; 279: L884–L894, [INFOTRIEVE], [CSA]
  • Short A D, Bian J, Ghosh T K, Waldron R T, Rybak S L, Gill D L. Intracellular Ca2+ pool content is linked to control of cell growth. Proc Natl Acad Sci USA 1993; 90: 4986–4990, [INFOTRIEVE], [CSA], [CROSSREF]
  • Shukla N, Rowe D, Hinton J, Angelini G D, Jeremy J Y. Calcium and the replication of human vascular smooth muscle cells: studies on the activation and translocation of extracellular signal regulated kinase (ERK) and cyclin D1 expression. Eur J Pharmacol 2005; 509: 21–30, [INFOTRIEVE], [CSA], [CROSSREF]
  • Smirnov S V, Robertson T P, Ward J P, Aaronson P I. Chronic hypoxia is associated with reduced delayed rectifier K+ current in rat pulmonary artery muscle cells. Am J Physiol 1994; 266: H365–H370, [INFOTRIEVE], [CSA]
  • Snetkov V A, Aaronson P I, Ward J P, Knock G A, Robertson T P. Capacitative calcium entry as a pulmonary specific vasoconstrictor mechanism in small muscular arteries of the rat. Br J Pharmacol 2003; 140: 97–106, [INFOTRIEVE], [CSA], [CROSSREF]
  • Staub N C. Site of hypoxic pulmonary vasoconstriction. Chest 1985; 88: 240S–245S, [INFOTRIEVE], [CSA]
  • Stevens T, Cornfield D N, McMurtry I F, Rodman D M. Acute reductions in PO2 depolarize pulmonary artery endothelial cells and decrease [Ca2+]i. Am J Physiol 1994; 266: H1416–H1421, [INFOTRIEVE], [CSA]
  • Suzuki H, Twarog B M. Membrane properties of smooth muscle cells in pulmonary hypertensive rats. Am J Physiol 1982; 242: H907–H915, [INFOTRIEVE], [CSA]
  • Sweeney M, Yu Y, Platoshyn O, Zhang S, McDaniel S S, Yuan J X. Inhibition of endogenous TRP1 decreases capacitative Ca2+ entry and attenuates pulmonary artery smooth muscle cell proliferation. Am J Physiol Lung Cell Mol Physiol 2002; 283: L144–L155, [INFOTRIEVE], [CSA]
  • Tiruppathi C, Freichel M, Vogel S M, Paria B C, Mehta D, Flockerzi V, Malik A B. Impairment of store-operated Ca2+ entry in TRPC4−/− mice interferes with increase in lung microvascular permeability. Circ Res 2002; 91: 70–76, [INFOTRIEVE], [CSA], [CROSSREF]
  • Tucker A, McMurtry I F, Grover R F, Reeves J T. Attenuation of hypoxic pulmonary vasoconstriction by verapamil in intact dogs. Proc Soc Exp Biol Med 1976; 151: 611–614, [INFOTRIEVE], [CSA]
  • Ullmer C, Boddeke H G, Schmuck K, Lubbert H. 5-HT2B receptor-mediated calcium release from ryanodine-sensitive intracellular stores in human pulmonary artery endothelial cells. Br J Pharmacol 1996; 117: 1081–1088, [INFOTRIEVE], [CSA]
  • Urena J, Franco-Obregon A, Lopez-Barneo J. Contrasting effects of hypoxia on cytosolic Ca2+ spikes in conduit and resistance myocytes of the rabbit pulmonary artery. J Physiol 1996; 496: 103–109, [INFOTRIEVE], [CSA]
  • Vadula M S, Kleinman J G, Madden J A. Effect of hypoxia and norepinephrine on cytoplasmic free Ca2+ in pulmonary and cerebral arterial myocytes. Am J Physiol 1993; 265: L591–L597, [INFOTRIEVE], [CSA]
  • Wang J, Juhaszova M, Rubin L J, Yuan X J. Hypoxia inhibits gene expression of voltage-gated K+ channel alpha subunits in pulmonary artery smooth muscle cells. J Clin Invest 1997; 100: 2347–2353, [INFOTRIEVE], [CSA]
  • Wang J, Shimoda L A, Sylvester J T. Capacitative calcium entry and TRPC channel proteins are expressed in rat distal pulmonary arterial smooth muscle. Am J Physiol Lung Cell Mol Physiol 2004; 286: L848–L858, [INFOTRIEVE], [CSA], [CROSSREF]
  • Wang J, Weigand L, Sylvester J, Shimoda L. Enhanced capacitative Ca2+ entry contributes to elevated resting Ca2+ and tension in pulmonary arterial smooth muscle from rats exposed to chronic hypoxia. Am Rev Repir Crit Care Med 2004; 169: A400, [CSA]
  • Wang J, Shimoda L A, Weigand L, Wang W, Sun D, Sylvester J T. Acute hypoxia increases intracellular [Ca2+] in pulmonary arterial smooth muscle by enhancing capacitative Ca2+ entry. Am J Physiol Lung Cell Mol Physiol 2005; 288: L1059–L1069, [INFOTRIEVE], [CSA], [CROSSREF]
  • Wang J, Weigand L, Wang W, Sylvester J T, Shimoda L A. Chronic hypoxia inhibits Kv channel gene expression in rat distal pulmonary artery. Am J Physiol Lung Cell Mol Physiol 2005; 288: L1049–L1058, [INFOTRIEVE], [CSA], [CROSSREF]
  • Wang J, Weigand L, Lu W, Sylvester J T, Semenza G L, Shimoda L A. Hypoxia inducible factor 1 mediates hypoxia-induced TRPC expression and elevated intracellular Ca2+ in pulmonary arterial smooth muscle cells. Circ Res 2006; 98: 1528–1537, [INFOTRIEVE], [CSA], [CROSSREF]
  • Wang Y X, Dhulipala P K, Kotlikoff M I. Hypoxia inhibits the Na+/Ca2+ exchanger in pulmonary artery smooth muscle cells. FASEB J 2000; 14: 1731–1740, [INFOTRIEVE], [CSA], [CROSSREF]
  • Waypa G B, Schumacker P T. O2 sensing in hypoxic pulmonary vasoconstriction: the mitochondrial door re-opens. Respir Physiol Neurobiol 2002; 132: 81–91, [INFOTRIEVE], [CSA], [CROSSREF]
  • Wei Z, Manevich Y, Al-Mehdi A B, Chatterjee S, Fisher A B. Ca2+ flux through voltage-gated channels with flow cessation in pulmonary microvascular endothelial cells. Microcirculation 2004; 11: 517–526, [INFOTRIEVE], [CSA], [CROSSREF]
  • Weigand L A, Sylvester J T, Shimoda L A. Mechanisms of endothelin-1-induced contraction in pulmonary arteries from chronically hypoxic rats. Am J Physiol Lung Cell Mol Physiol 2006; 290: L284–L290, [INFOTRIEVE], [CSA], [CROSSREF]
  • Wellman G C, Nelson M T. Signaling between SR and plasmalemma in smooth muscle: sparks and the activation of Ca2+-sensitive ion channels. Cell Calcium 2003; 34: 211–229, [INFOTRIEVE], [CSA], [CROSSREF]
  • Wesson D E, Elliott S J. The H2O2-generating enzyme, xanthine oxidase, decreases luminal Ca2+ content of the IP3-sensitive Ca2+ store in vascular endothelial cells. Microcirculation 1995; 2: 195–203, [INFOTRIEVE], [CSA]
  • Whorton A R, Willis C E, Kent R S, Young S L. The role of calcium in the regulation of prostacyclin synthesis by porcine aortic endothelial cells. Lipids 1984; 19: 17–24, [INFOTRIEVE], [CSA]
  • Wu S, Haynes J, Jr., Taylor J T, Obiako B O, Stubbs J R, Li M, Stevens T. Cav3.1 (alpha1G) T-type Ca2+ channels mediate vaso-occlusion of sickled erythrocytes in lung microcirculation. Circ Res 2003; 93: 346–353, [INFOTRIEVE], [CSA], [CROSSREF]
  • Yang H, Mergler S, Sun X, Wang Z, Lu L, Bonanno J A, Pleyer U, Reinach P S. TRPC4 knockdown suppresses epidermal growth factor-induced store-operated channel activation and growth in human corneal epithelial cells. J Biol Chem 2005; 280: 32230–32237, [INFOTRIEVE], [CSA], [CROSSREF]
  • Yang X R, Lin M J, Yip K P, Jeyakumar L H, Fleischer S, Leung G P, Sham J S. Multiple ryanodine receptor subtypes and heterogeneous ryanodine receptor-gated Ca2+ stores in pulmonary arterial smooth muscle cells. Am J Physiol Lung Cell Mol Physiol 2005; 289: L338–L348, [INFOTRIEVE], [CSA], [CROSSREF]
  • Yang X R, Lin M J, McIntosh L S, Sham J S. Functional expression of transient receptor potential melastatin- and vanilloid-related channels in pulmonary arterial and aortic smooth muscle. Am J Physiol Lung Cell Mol Physiol 2006; 290: L1267–L1276, [INFOTRIEVE], [CSA], [CROSSREF]
  • Yu Y, Sweeney M, Zhang S, Platoshyn O, Landsberg J, Rothman A, Yuan J X. PDGF stimulates pulmonary vascular smooth muscle cell proliferation by upregulating TRPC6 expression. Am J Physiol Cell Physiol 2003; 284: C316–C330, [INFOTRIEVE], [CSA]
  • Yuan X J. Voltage-gated K+ currents regulate resting membrane potential and [Ca2+]i in pulmonary arterial myocytes. Circ Res 1995; 77: 370–378, [INFOTRIEVE], [CSA]
  • Zhang F, Carson R C, Zhang H, Gibson G, Thomas H M, 3rd. Pulmonary artery smooth muscle cell [Ca2+]i and contraction: responses to diphenyleneiodonium and hypoxia. Am J Physiol 1997; 273: L603–L611, [INFOTRIEVE], [CSA]
  • Zhang S, Yuan J X, Barrett K E, Dong H. Role of Na+/Ca2+ exchange in regulating cytosolic Ca2+ in cultured human pulmonary artery smooth muscle cells. Am J Physiol Cell Physiol 2005; 288: C245–C252, [INFOTRIEVE], [CSA], [CROSSREF]
  • Zhang W M, Yip K P, Lin M J, Shimoda L A, Li W H, Sham J S. ET-1 activates Ca2+ sparks in PASMC: local Ca2+ signaling between inositol trisphosphate and ryanodine receptors. Am J Physiol Lung Cell Mol Physiol 2003; 285: L680–L690, [INFOTRIEVE], [CSA]
  • Zheng Y M, Mei Q B, Wang Q S, Abdullaev I, Lai F A, Xin H B, Kotlikoff M I, Wang Y X. Role of FKBP12.6 in hypoxia- and norepinephrine-induced Ca2+ release and contraction in pulmonary artery myocytes. Cell Calcium 2004; 35: 345–355, [INFOTRIEVE], [CSA], [CROSSREF]
  • Zheng Y M, Wang Q S, Rathore R, Zhang W H, Mazurkiewicz J E, Sorrentino V, Singer H A, Kotlikoff M I, Wang Y X. Type-3 ryanodine receptors mediate hypoxia-, but not neurotransmitter-induced calcium release and contraction in pulmonary artery smooth muscle cells. J Gen Physiol 2005; 125: 427–440, [INFOTRIEVE], [CSA], [CROSSREF]
  • Ziegelstein R C, Spurgeon H A, Pili R, Passaniti A, Cheng L, Corda S, Lakatta E G, Capogrossi M C. A functional ryanodine-sensitive intracellular Ca2+ store is present in vascular endothelial cells. Circ Res 1994; 74: 151–156, [INFOTRIEVE], [CSA]
  • Zucchi R, Ronca-Testoni S. The sarcoplasmic reticulum Ca2 + channel/ryanodine receptor: modulation by endogenous effectors, drugs and disease states. Pharmacol Rev 1997; 49: 1–51, [INFOTRIEVE], [CSA]

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.