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Research Article

Comparative Binding of 125I-and 99mTc-Labeled Native and Glycated Low-Density Lipoprotein to Human Microvascular Endothelial Cells-Potential for Atherosclerosis Imaging?

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Pages 693-707 | Published online: 10 Oct 2008

REFERENCES

  • Steinbrecher U P, Lougheed M, Kwan Wing-Cheung, Dirks M. Recognition of low density lipoprotein by scavenger receptor of macrophages results from derivatization of apolipoprotein B by products of fatty acid peroxidation. J Biol Chem 1989; 264: 15216–15223
  • Költringer P, Jürgens G. A dominant role of lipoprotein(a) in the investigation and evaluation of parameters indicating the development of cervical atherosclerosis. Atherosclerosis 1985; 58: 187–198
  • Kawamori R, Yamasaki Y, Matsushima H, Nishizawa H, Nao K, Hougaku H, Maeda H, Handa N, Matsumoto M, Kamada T. Prevalence of carotid atherosclerosis in diabetic patients. Ultrasound high-resolution B-mode imaging on carotid arteries. Diabetes Care 1992; 15: 1290–1294
  • Hunt J V, Smith C CT, Wolff S P. Autoxidative glycosylation and possible involvement of peroxides and free radicals in LDL modification by glucose. Diabetes 1990; 39: 1420–1424
  • Cominacini L, Garbin U, Pastorino A M. Increased susceptibility of LDL to in vitro oxidation in patients with insulin-dependent and non-insulin-dependent diabetes mellitus. Diabetes Res 1994; 26: 173–184
  • Bucala R, Makita Z, Koschinsky T, Cerami A, Vlassara H. Lipid advanced glycosylation: Pathway for lipid oxidation in vivo. Proc Natl Acad Sci USA 1993; 90: 6434–6438
  • Menzel E J, Sobal G, Staudinger A. The role of oxidative stress in the long-term glycation of LDL. Biofactors 1997; 6: 111–124
  • Napoli C, Triggiani M, Palumbo G, Condorelli M, Chiariello M, Ambrosio G. Glycosylation enhances oxygen radical-induced modifications and decreases acetylhydrolase activity of human low density lipoprotein. Basic Res Cardiol 1997; 92: 96–105
  • Sobal G, Menzel E J, Sinzinger H. Why is glycated LDL more sensitive to oxidation than native LDL? A comparative study. Prostaglandins Leukot Essent Fatty Acids 2000; 63: 177–186
  • Bucala R, Makita Z, Vega G, Grundy S, Koschinsky T, Cerami A, Vlassara H. Modification of low density lipoprotein by advanced glycation end products contributes to the dyslipidemia of diabetes and renal insufficiency. Proc Natl Acad Sci USA 1994; 91: 9441–9445
  • Brownlee M. Glycation and diabetic complication. Diabetes 1994; 43: 836–841
  • Jinnouchi Y, Sano H, Nagai R, Hakamata H, Kodama T, Suzuki H, Yoshida M, Ueda S, Horiuchi S. Glycolaldehyde-modified low density lipoprotein leads macrophages to foam cells via the macrophage scavenger receptor. J Biochem Tokyo 1998; 123: 1208–1217
  • Dobrian A, Lazar V, Tirziu D, Simionescu M. Increased macrophage uptake of irreversibly glycated albumin modified-low density lipoproteins of normal and diabetic subjects is mediated by non-saturable mechanisms. Biochim Biophys Acta 1996; 1317: 5–14
  • Lees R S, Lees A M, Strauss H W. External imaging of human atherosclerosis. J Nucl Med 1983; 24: 154–156
  • Lees R S, Garabedian H D, Lees A M, Schumacher D J, Miller A, Isaacsohn J L, Strauss H W. Tc-99m low density lipoproteins: Preparation and biodistribution. J Nucl Med 1985; 26: 1056–1062
  • Mc Carthy P A. New approaches to atherosclerosis: An overview. Med Res Rev 1993; 13: 139–159
  • Yamashina H. Evaluation of biodistribution and imaging of atherosclerotic lesions using 111In-labeled low-density lipoprotein. Kaku-Igaku 1993; 30: 769–778
  • Virgolini I, Angelberger P, O'Grady J, Sinzinger H. Low density lipoprotein labelling characterizes experimentally induced atherosclerotic lesions in rabbits in vivo as to presence of foam cells and endothelial coverage. Eur J Nucl Med 1991; 8: 944–947
  • Lees A M, Lees R S, Schoen F J, Isaacsohn J L, Fischman A J, McKusick K A, Strauss H W. Imaging human atherosclerosis with 99mTc-labeled low density lipoproteins. Arteriosclerosis 1988; 8: 461–470
  • Iuliano L, Signore A, Vallabajosula S, Camastra C, Ronga G, Alessandri C, Sbarigia E, Fiorani P, Violi F. Preparation and biodistribution of 99mtechnetium-labelled oxidized LDL in man. Atherosclerosis 1996; 126: 131–141
  • Tsimikas S, Palinski W, Halpern S E, Yeung D W, Curtiss L K, Witztum J L. Radiolabeled MDA2, an oxidation-specific, monoclonal antibody, identifies native atherosclerotic lesions in vivo. J Nucl Cardiol 1999; 6: 41–53
  • Havel R J, Eder H A, Bragdon J H. The distribution and chemical composition of ultracentrifugally separeted lipoproteins in human serum. J Clin Invest 1985; 34: 1345–1353
  • Lowry O H, Rosebrough N J, Farr A L, Randall R J. Protein measurement with Folin phenol reagent. J Biol Chem 1951; 193: 265–275
  • Panteghini M, Bonora R, Pagani F. Determination of glycated apolipoprotein B in serum by a combination of affinity chromatography and immunonephelometry. Ann Clin Biochem 1994; 31: 544–549
  • Buege J A, Aust S D. Lactoperoxidase-catalyzed lipid peroxidation of microsomal and artifical membranes. Biochim Biophys Acta 1976; 444: 192–201
  • McConahey P J, Dixon F J. A method of trace iodination of proteins for immunologic studies. Int Arch Allergy 1966; 29: 185–187
  • Tontonoz P, Nagy L, Alvarez J G, Thomazy V A, Evans R M. PPARγ promotes monocyte-macrophage differentiation and uptake of oxidized LDL. Cell 1998; 93: 241–252
  • Van der Kooij M A, von der Mark E M, Kruijt J K, van Velzen A, van Berkel T J, Morand O H. Human monocyte-derived macrophages express an approximately 120 kD ox-LDL binding protein with strong identity to CD68. Arterioscler Thromb Vasc Biol 1997; 17: 3107–3116
  • Atsma D E, Feitsma R I, Camps J, van't Hooft F M, van der Wall E E, Nieuwzenhuizen W, Pauwels E K. Potential of 99mTc-LDLs labeled with two different methods for scintigraphic detection of experimental atherosclerosis in rabbits. Arterioscler Thromb 1993; 13: 78–83
  • Lees A M, Lees R S. 99mTc-labeled LDL: Receptor recognition and intracellular sequestration of radiolabel. J Lipid Res 1991; 32: 1–8
  • Virgolini I, Angelberger P, Li S R, Koller F, Pidlich J, Lupattelli G, Sinzinger H. Indium-111-labeled low-density lipoprotein binds with higher affinity to the human liver as compared to iodine-123-low-density-labeled lipoprotein. J Nucl Med 1991; 32: 2132–2138
  • Moriwaki H, Kume S, Sawamura T, Aoyama T, Hoshikawa H, Ochi H, Nishi E, Masaki T, Kita T. Ligand specificity of LOX-1, a novel endothelial receptor for oxidized low density lipoprotein. Arterioscler Thromb Vasc Biol 1998; 18: 1541–1547

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