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Original Articles

CBD (Cannabidiol) Product Attitudes, Knowledge, and Use Among Young Adults

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References

  • Abrams, D. I., Jay, C. A., Shade, S. B., Vizoso, H., Reda, H., Press, S., … Petersen, K. L. (2007). Cannabis in painful HIV-associated sensory neuropathy: A randomized placebo-controlled trial. Neurology, 68(7), 515–521. doi:10.1212/01.wnl.0000253187.66183.9c
  • Aizpurua-Olaizola, O., Soydaner, U., Öztürk, E., Schibano, D., Simsir, Y., Navarro, P., … Usobiaga, A. (2016). Evolution of the cannabinoid and terpene content during the growth of Cannabis sativa plants from different chemotypes. Journal of Natural Products, 79(2), 324–331. doi:10.1021/acs.jnatprod.5b00949
  • Axon, D. R., Vanova, J., Edel, C., & Slack, M. (2017). Dietary supplement use, knowledge, and perceptions among student pharmacists. American Journal of Pharmaceutical Education, 81(10), 6854–6812. doi:10.5688/ajpe6854
  • Bergamaschi, M. M., Queiroz, R. H. C., Chagas, M. H. N., de Oliveira, D. C. G., De Martinis, B. S., Kapczinski, F., … Crippa, J. A. S. (2011). Cannabidiol reduces the anxiety induced by simulated public speaking in treatment-naive social phobia patients. Neuropsychopharmacology, 36(6), 1219–1226. doi:10.1038/npp.2011.6
  • Bonn-Miller, M. O., Loflin, M. J. E., Thomas, B. F., Marcu, J. P., Hyke, T., & Vandrey, R. (2017). Labeling accuracy of cannabidiol extracts sold online. JAMA, 318(17), 1708–1709. doi:10.1001/jama.2017.11909
  • Bornheim, L. M., & Correia, M. A. (1990). Selective inactivation of mouse liver cytochrome P-450IIIA by cannabidiol. Molecular Pharmacology, 38(3), 319–326.
  • Bornheim, L. M., Everhart, E. T., Li, J., & Correia, M. A. (1994). Induction and genetic regulation of mouse hepatic cytochrome P450 by cannabidiol. Biochemical Pharmacology, 48(1), 161–171. doi:10.1016/0006-2952(94)90236-4
  • Campos, A. C., Fogaça, M. V., Sonego, A. B., & Guimarães, F. S. (2016). Cannabidiol, neuroprotection and neuropsychiatric disorders. Pharmacological Research, 112, 119–127. doi:10.1016/j.phrs.2016.01.033
  • Cohen, P. A., Maller, G., DeSouza, R., & Neal-Kababick, J. (2014). Presence of banned drugs in dietary supplements following FDA recalls. JAMA, 312(16), 1691–1693. doi:10.1001/jama.2014.10308
  • Corroon, J., & Kight, R. (2018). Regulatory status of cannabidiol in the United States: A perspective. Cannabis and Cannabinoid Research, 3(1), 190–194. doi:10.1089/can.2018.0030
  • Corroon, J., & Phillips, J. A. (2018). A cross-sectional study of cannabidiol users. Cannabis and Cannabinoid Research, 3(1), 152–61. doi:10.1089/can.2018.0006
  • Devinsky, O., Cross, J. H., Laux, L., Marsh, E., Miller, I., Nabbout, R., … Wright, S. (2017). Cannabidiol in Dravet syndrome study group. Trial of cannabidiol for drug-resistant seizures in the Dravet syndrome. New England Journal of Medicine, 376(21), 2011–2020. doi:10.1056/NEJMoa1611618
  • Epidiolex Highlights of Prescribing Information. 2018. Retrieved from https://www.accessdata.fda.gov/drugsatfda_docs/label/2018/210365lbl.pdf
  • Ewing, L. E., Skinner, C. M., Quick, C. M., Kennon-McGill, S., McGill, M. R., Walker, L. A., … Koturbash, I. (2019). Hepatotoxicity of a cannabidiol-rich cannabis extract in the mouse model. Molecules, 24(9), 1694. doi:10.3390/molecules24091694
  • Expert Committee on Drug Dependence. (2017). World Health Organization (WHO). Cannabidiol (CBD) pre-review report (Thirty-Ninth Meeting). Retrieved from https://www.who.int/medicines/access/controlled-substances/5.2_CBD.pdf
  • Expert Committee on Drug Dependence. (2018). World Health Organization (WHO). Cannabidiol (CBD) critical review report (Fortieth Meeting). Retrieved from https://www.who.int/medicines/access/controlled-substances/CannabidiolCriticalReview.pdf
  • Hložek, T., Uttl, L., Kadeřábek, L., Balíková, M., Lhotková, E., Horsley, R. R., … Páleníček, T. (2017). Pharmacokinetics and behavioural profile of THC, CBD, and THC + CBD combination after pulmonary, oral, and subcutaneous administration in rats and confirmation of conversion in vivo of CBD to THC. European Neuropsychopharmacology, 27(12), 1223–1237. doi:10.1016/j.euroneuro.2017.10.037
  • Homer, P. M., & Mukherjee, S. (2018). The impact of dietary supplement form and dosage on perceived efficacy. Journal of Consumer Marketing, 35(2), 228–238. doi:10.1108/JCM-02-2017-2108
  • Hurd, Y. L., Spriggs, S., Alishayev, J., Winkel, G., Gurgov, K., Kudrich, C., … Salsitz, E. (2019). Cannabidiol for the reduction of cue-induced craving and anxiety in drug-abstinent individuals with heroin use disorder: A double-blind randomized placebo-controlled trial. American Journal of Psychiatry, 176(11), 1–12. doi:10.1176/appi.ajp.2019.18101191
  • Iffland, K., & Grotenhermen, F. (2017). An update on safety and side effects of cannabidiol: A review of clinical data and relevant animal studies. Cannabis and Cannabinoid Research, 2, 139–154. doi:10.1089/can.2016.0034
  • Kaplan, S. (2019, May). Cannabis companies push F.D.A. to ease rules on CBD products. The New York Times. Retrieved from https://www.nytimes.com/2019/05/31/health/cannabis-fda-regulate.html
  • Knapik, J. J., Trone, D. W., Austin, K. G., Steelman, R. A., Farina, E. K., & Lieberman, H. R. (2016). Prevalence, adverse events, and factors associated with dietary supplement and nutritional supplement use by US navy and marine corps personnel. Journal of the Academy of Nutrition and Dietetics, 116, 1423–1442. doi:10.1016/j.jand.2016.02.015
  • Koenig, C. J., Ho, E. Y., Yadegar, V., & Tarn, D. M. (2012). Negotiating complementary and alternative medicine use in primary care visits with older patients. Patient Education and Counseling, 89, 368–373. doi:10.1016/j.pec.2012.02.020
  • Linares, I. M., Zuardi, A. W., Pereira, L. C., Queiroz, R. H., Mechoulam, R., Guimarães, F. S., & Crippa, J. A. (2019). Cannabidiol presents an inverted U-shaped dose-response curve in simulated public speaking test. Brazilian Journal of Psychiatry, 41(1), 9–14.
  • Massad, S. J., Hamdan, M., Agha, H., & Amr, A. (2017). Sports nutrition supplement use: Comparison between a USA and a Palestinian community. International Journal of Science Commerce & Humanities, 5, 25–41.
  • Maughan, R. J., King, D. S., & Lea, T. (2004). Dietary supplements. Journal of Sports Sciences, 22(1), 95–113. doi:10.1080/0264041031000140581
  • McGuire, P., Robson, P., Cubala, W. J., Vasile, D., Morrison, P. D., Barron, R., … Wright, S. (2018). Cannabidiol (CBD) as an adjunctive therapy in schizophrenia: A multicenter randomized controlled trial. American Journal of Psychiatry, 175(3), 225–231. doi:10.1176/appi.ajp.2017.17030325
  • Mead, A. (2017). The legal status of cannabis (marijuana) and cannabidiol (CBD) under U.S. law. Epilepsy & Behavior : E&B, 70(Pt B), 288–291. doi:10.1016/j.yebeh.2016.11.021
  • Narimatsu, S., Watanabe, K., Matsunaga, T., Yamamoto, I., Imaoka, S., Funae, Y., … Yoshimura, H. (1990). Inhibition of hepatic microsomal cytochrome P450 by cannabidiol in adult male rats. Chemical & Pharmaceutical Bulletin, 38, 1365–1368. doi:10.1248/cpb.38.1365
  • NIH US National Library of Medicine. (2019). ClinicalTrials.gov. Retrieved from https://clinicaltrials.gov/ct2/results?cond=&term=cannabidiol&cntry=&state=&city=&dist=&Search=Search
  • Pain, S. (2015). A potted history. Nature, 525(7570), S10–S11. doi:10.1038/525S10a
  • Pavlovic, R., Nenna, G., Calvi, L., Panseri, S., Borgonovo, G., Giupponi, L., … Giorgi, A. (2018). Quality traits of “cannabidiol oils”: Cannabinoids content, terpene fingerprint and oxidation stability of European commercially available preparations. Molecules, 23(5), 1230–1222. doi:10.3390/molecules23051230
  • Peace, M. R., Butler, K. E., Wolf, C. E., Poklis, J. L., & Poklis, A. (2016). Evaluation of two commercially available cannabidiol formulations for use in electronic cigarettes. Frontiers in Pharmacology, 7(279), 1–6. doi:10.3389/fphar.2016.00279
  • Pisanti, S., Malfitano, A. M., Ciaglia, E., Lamberti, A., Ranieri, R., & Cuomo, G. (2017). Cannabidiol: State of the art and new challenges for therapeutic application. Pharmacology & Therapeutics, 175, 133–150. doi:10.1016/j.pharmthera.2017.02.041
  • Rong, C., Lee, Y., Carmona, N. E., Cha, D. S., Ragguett, R.-M., Rosenblat, J. D., … McIntyre, R. S. (2017). Cannabidiol in medical marijuana: Research vistas and potential opportunities. Pharmacological Research, 121, 213–218. doi:10.1016/j.phrs.2017.05.005
  • Schoedel, K. A., Szeto, I., Setnik, B., Sellers, E. M., Levy-Cooperman, N., Mills, C., … Sommerville, K. (2018). Abuse potential assessment of cannabidiol (CBD) in recreational polydrug users: A randomized, double-blind, controlled trial. Epilepsy & Behavior, 88, 162–171. doi:10.1016/j.yebeh.2018.07.027
  • Shannon, S., Lewis, N., Lee, H., & Hughes, S. (2019). Cannabidiol in anxiety and sleep: A large case series. The Permanente Journal, 23, 18–041. doi:10.7812/TPP/18-041
  • Silote, G. P., Sartim, A., Sales, A., Eskelund, A., Guimaraes, F. S., Wegener, G., … Joca, S. (2019). Emerging evidence for the antidepressant effect of cannabidiol and the underlying molecular mechanisms. Journal of Chemical Neuroanatomy, 98, 104–116. doi:10.1016/j.jchemneu.2019.04.006
  • Starr, R. R. (2015). Too little, too late: Ineffective regulation of dietary supplements in the United States. American Journal of Public Health, 105(3), 478–485. doi:10.2105/AJPH.2014.302348
  • Tarn, D. M., Paterniti, D. A., Good, J. S., Coulter, I. D., Galliher, J. M., & Kravitz, R. L. (2013). Physician-patient communication about dietary supplements. Patient Education and Counseling, 91, 287–294. doi:10.1016/j.pec.2013.01.021
  • U.S. Food and Drug Administration. (2019). Warning letters and test results for cannabidiol related products. Retrieved from https://www.fda.gov/news-events/public-health-focus/warning-letters-and-test-results-cannabidiol-related-products
  • Yamaori, S., Ebisawa, J., Okushima, Y., Yamamoto, I., & Watanabe, K. (2011). Potent inhibition of human cytochrome P450 3A isoforms by cannabidiol: Role of phenolic hydroxyl groups in resorcinol moiety. Life Sciences, 88(15–16), 730–736. doi:10.1016/j.lfs.2011.02.017
  • Zhomitsky, S., & Potvin, S. (2012). Cannabidiol in humans–the quest for therapeutic targets. Pharmaceuticals ( Pharmaceuticals), 5(5), 529–552. doi:10.3390/ph5050529
  • Zuardi, A. W., Cosme, R. A., Graeff, F. G., & Guimaraes, F. S. (1993). Effects of ipsapirone and cannabidiol on human experimental anxiety. Journal of Psychopharmacology, 7(1_suppl), 82–88. doi:10.1177/026988119300700112
  • Zuardi, A. W., Rodrigues, N. P., Silva, A. L., Bernardo, S. A., Hallak, J. E. C., Guimaraes, F. S., … Crippa, J. A. S. (2017). Inverted U-shaped dose-response curve of the anxiolytic effect of cannabidiol during public speaking in real life. Frontiers in Pharmacology, 8, 259. doi:10.3389/fphar.2017.00259
  • Zuk-Golaszewska, K., & Golaszewski, J. (2018). Cannabis sativa L.- Cultivation and quality of raw material. Journal of Elementology, 23(3), 971–984. doi:10.5601/jelem.2017.22.3.1500

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