Characterizing Opioid Withdrawal Experiences and Consequences Among a Community Sample of People Who Use Opioids

References

• Adams, K., Miech, E., & Sobieraj, D. (2022). Factors that distinguish opioid withdrawal during induction with buprenorphine microdosing: A configurational analysis. Addiction Science & Clinical Practice, 17(1), 55. https://doi.org/10.1186/s13722-022-00336-z
   PubMed Web of Science ®Google Scholar
• Albayati, A., Douedi, S., Alshami, A., Hossain, M. A., Sen, S., Buccellato, V., Cutroneo, A., Beelitz, J., & Asif, A. (2021). Why Do patients leave against medical advice? Reasons, consequences, prevention, and interventions. Healthcare (Basel, Switzerland), 9(2), 111. https://doi.org/10.3390/healthcare9020111
   PubMedGoogle Scholar
• Azar, P., Mathew, N., Mahal, D., Wong, J. S. H., Westenberg, J. N., Schütz, C. G., & Greenwald, M. K. (2023). Developing a rapid transfer from opioid full agonist to buprenorphine: “Ultrarapid micro-dosing” proof of concept. Journal of Psychoactive Drugs, 55(1), 94–101. https://doi.org/10.1080/02791072.2022.2039814
   PubMed Web of Science ®Google Scholar
• Bluthenthal, R., Goldshear, J., Wilkins, P., Page, C., Kral, A. H., Kovalsky, E., Simpson K.A., Portillo, G.O., Corsi, K.(2023). Adapting to an unsafe drug supply: Evidence of changes in drug use ingestion methods among people who inject drugs in Los Angeles, CA and Denver, CO, 2021 to 2022. Paper presented at the Harm Reduction International Conference 2023, Melbourne, Australia.
   Google Scholar
• Bluthenthal, R., Simpson, K., Ceasar, R., Zhao, J., Wenger, L., & Kral, A. (2020). Opioid withdrawal symptoms, frequency, and pain characteristics as correlates of health risk among people who inject drugs. Drug & Alcohol Dependence, 211, 107932.
   PubMed Web of Science ®Google Scholar
• Bluthenthal, R., & Watters, J. (1995). Multimethod research from targeted sampling to HIV risk environments. NIDA Research Monograph, 157, 212–230.
   PubMedGoogle Scholar
• Bolinski, R. S., Walters, S., Salisbury-Afshar, E., Ouellet, L. J., Jenkins, W. D., Almirol, E., Van Ham, B., Fletcher, S., Johnson, C., Schneider, J. A., Ompad, D., & Pho, M. T. (2022). The impact of the COVID-19 pandemic on drug use behaviors, fentanyl exposure, and harm reduction service support among people who use drugs in rural settings. International Journal of Environmental Research and Public Health, 19(4), 2230. https://doi.org/10.3390/ijerph19042230
   PubMed Web of Science ®Google Scholar
• Braun, V., & Clarke, V. (2006). Using thematic analysis in psychology. Qualitative Research in Psychology, 3(2), 77–101. https://doi.org/10.1191/1478088706qp063oa
   Google Scholar
• Buresh, M., Genberg, B. L., Astemborski, J., Kirk, G. D., & Mehta, S. H. (2019). Recent fentanyl use among people who inject drugs: Results from a rapid assessment in Baltimore, Maryland. The International Journal on Drug Policy, 74, 41–46. https://doi.org/10.1016/j.drugpo.2019.08.006
   PubMed Web of Science ®Google Scholar
• Chandra, D. K., Altice, F. L., Copenhaver, M. M., Zhou, X., Didomizio, E., & Shrestha, R. (2021). Purposeful fentanyl use and associated factors among opioid-dependent people who inject drugs. Substance Use & Misuse, 56(7), 979–987. https://doi.org/10.1080/10826084.2021.1901931
   PubMed Web of Science ®Google Scholar
• Coffin, P. O., Tracy, M., Bucciarelli, A., Ompad, D., Vlahov, D., & Galea, S. (2007). Identifying injection drug users at risk of nonfatal overdose. Academic Emergency Medicine: Official Journal of the Society for Academic Emergency Medicine, 14(7), 616–623. https://doi.org/10.1197/j.aem.2007.04.005
   PubMed Web of Science ®Google Scholar
• Daniels, A. M., Salisbury-Afshar, E., Hoffberg, A., Agus, D., & Fingerhood, M. I. (2014). A novel community-based buprenorphine program: Client description and initial outcomes. Journal of Addiction Medicine, 8(1), 40–46. https://doi.org/10.1097/ADM.0000000000000004
   PubMed Web of Science ®Google Scholar
• Darke, S., Larney, S., & Farrell, M. (2017). Yes, people can die from opiate withdrawal. Addiction (Abingdon, England), 112(2), 199–200. https://doi.org/10.1111/add.13512
   PubMed Web of Science ®Google Scholar
• Evans, C. J., & Cahill, C. M. (2016). Neurobiology of opioid dependence in creating addiction vulnerability. F1000Research, 5, 1748. https://doi.org/10.12688/f1000research.8369.1
   Google Scholar
• Friedman, J., Bourgois, P., Godvin, M., Chavez, A., Pacheco, L., Segovia, L. A., Beletsky, L., & Arredondo, J. (2022). The introduction of fentanyl on the US-Mexico border: An ethnographic account triangulated with drug checking data from Tijuana. The International Journal on Drug Policy, 104, 103678. https://doi.org/10.1016/j.drugpo.2022.103678
   PubMed Web of Science ®Google Scholar
• Gilchrist, G., Swan, D., Widyaratna, K., Marquez-Arrico, J. E., Hughes, E., Mdege, N. D., Martyn-St James, M., & Tirado-Munoz, J. (2017). A systematic review and meta-analysis of psychosocial interventions to reduce drug and sexual blood borne virus risk behaviours among people who inject drugs. AIDS and Behavior, 21(7), 1791–1811. https://doi.org/10.1007/s10461-017-1755-0
   PubMed Web of Science ®Google Scholar
• Goldfine, C. E., Chapman, B. P., Taylor, M. M., Bradley, E. S., Carreiro, S. P., Rosen, R. K., Babu, K. M., & Lai, J. T. (2023). Experiences with medications for addiction treatment among emergency department patients with opioid use disorder. The Western Journal of Emergency Medicine, 24(2), 236–242. https://doi.org/10.5811/westjem.2022.9.57821
   PubMed Web of Science ®Google Scholar
• Gowing, L., Farrell, M., Bornemann, R., & Ali, R. (2004). Substitution treatment of injecting opioid users for prevention of HIV infection. The Cochrane Database of Systematic Reviews, (4), CD004145. https://doi.org/10.1002/14651858.CD004145.pub2
   PubMedGoogle Scholar
• Hodder, S. L., Feinberg, J., Strathdee, S. A., Shoptaw, S., Altice, F. L., Ortenzio, L., & Beyrer, C. (2021). The opioid crisis and HIV in the USA: Deadly synergies. Lancet (London, England), 397(10279), 1139–1150. https://doi.org/10.1016/s0140-6736(21)00391-3
   PubMed Web of Science ®Google Scholar
• Ivsins, A., Boyd, J., Beletsky, L., & McNeil, R. (2020). Tackling the overdose crisis: The role of safe supply. The International Journal on Drug Policy, 80, 102769. https://doi.org/10.1016/j.drugpo.2020.102769
   PubMed Web of Science ®Google Scholar
• Kilmer, B., Pardo, B., Pujol, T. A., & Caulkins, J. P. (2022). Rapid changes in illegally manufactured fentanyl products and prices in the United States. Addiction (Abingdon, England), 117(10), 2745–2749. https://doi.org/10.1111/add.15942
   PubMed Web of Science ®Google Scholar
• Knight, K. R. (2015). Addicted pregnant poor critical global health: Evidence, efficacy, ethnography (pp. 1 online resource (320 p.)).
   Google Scholar
• Kosten, T. R., & Baxter, L. E. (2019). Review article: Effective management of opioid withdrawal symptoms: A gateway to opioid dependence treatment. The American Journal on Addictions, 28(2), 55–62. https://doi.org/10.1111/ajad.12862
   PubMed Web of Science ®Google Scholar
• Kral, A. H., Lambdin, B. H., Browne, E. N., Wenger, L. D., Bluthenthal, R. N., Zibbell, J. E., & Davidson, P. J. (2021). Transition from injecting opioids to smoking fentanyl in San Francisco, California. Drug and Alcohol Dependence, 227, 109003. https://doi.org/10.1016/j.drugalcdep.2021.109003
   PubMed Web of Science ®Google Scholar
• Kral, A. H., Malekinejad, M., Vaudrey, J., Martinez, A. N., Lorvick, J., Mcfarland, W., & Raymond, H. F. (2010). Comparing respondent-driven sampling and targeted sampling methods of recruiting injection drug users in San Francisco. Journal of Urban Health: Bulletin of the New York Academy of Medicine, 87(5), 839–850. https://doi.org/10.1007/s11524-010-9486-9
   PubMed Web of Science ®Google Scholar
• Lambdin, B. H., Bluthenthal, R. N., Zibbell, J., Wenger, L., Simpson, K. A., & Kral, A. (2019). Associations between illicit fentanyl use and infectious disease risks among people who inject drugs. The International Journal on Drug Policy, 74, 299–304. https://doi.org/10.1016/j.drugpo.2019.10.004
   PubMed Web of Science ®Google Scholar
• Latkin, C. A., Forman, V., Knowlton, A., & Sherman, S. (2003). Norms, social networks, and HIV-related risk behaviors among urban disadvantaged drug users. Social Science & Medicine (1982), 56(3), 465–476. https://doi.org/10.1016/s0277-9536(02)00047-3
   PubMed Web of Science ®Google Scholar
• MacArthur, G. J., Minozzi, S., Martin, N., Vickerman, P., Deren, S., Bruneau, J., Degenhardt, L., & Hickman, M. (2012). Opiate substitution treatment and HIV transmission in people who inject drugs: Systematic review and meta-analysis. BMJ (Clinical Research ed.), 345(oct03 3), e5945–e5945. https://doi.org/10.1136/bmj.e5945
   PubMedGoogle Scholar
• Mateu-Gelabert, P., Jessell, L., Goodbody, E., Kim, D., Gile, K., Teubl, J., Syckes, C., Ruggles, K., Lazar, J., Friedman, S., & Guarino, H. (2017). High enhancer, downer, withdrawal helper: Multifunctional nonmedical benzodiazepine use among young adult opioid users in New York City. The International Journal on Drug Policy, 46, 17–27. https://doi.org/10.1016/j.drugpo.2017.05.016
   PubMed Web of Science ®Google Scholar
• Mateu-Gelabert, P., Sandoval, M., Meylakhs, P., Wendel, T., & Friedman, S. R. (2010). Strategies to avoid opiate withdrawal: Implications for HCV and HIV risks. The International Journal on Drug Policy, 21(3), 179–185. https://doi.org/10.1016/j.drugpo.2009.08.007
   PubMed Web of Science ®Google Scholar
• Mcneil, R., Small, W., Wood, E., & Kerr, T. (2014). Hospitals as a ‘risk environment’: An ethno-epidemiological study of voluntary and involuntary discharge from hospital against medical advice among people who inject drugs. Social Science & Medicine (1982), 105, 59–66. https://doi.org/10.1016/j.socscimed.2014.01.010
   PubMed Web of Science ®Google Scholar
• Merrill, J. O., Rhodes, L. A., Deyo, R. A., Marlatt, G. A., & Bradley, K. A. (2002). Mutual mistrust in the medical care of drug users: The keys to the “narc” cabinet. Journal of General Internal Medicine, 17(5), 327–333. https://doi.org/10.1007/s11606-002-0034-5
   PubMed Web of Science ®Google Scholar
• Motavalli, D., Taylor, J. L., Childs, E., Valente, P. K., Salhaney, P., Olson, J., Biancarelli, D. L., Edeza, A., Earlywine, J. J., Marshall, B. D. L., Drainoni, M.-L., Mimiaga, M. J., Biello, K. B., & Bazzi, A. R. (2021). Health is on the back burner:” Multilevel barriers and facilitators to primary care among people who inject drugs. Journal of General Internal Medicine, 36(1), 129–137. https://doi.org/10.1007/s11606-020-06201-6
   PubMed Web of Science ®Google Scholar
• Nordeck, C. D., Buresh, M., Krawczyk, N., Fingerhood, M., & Agus, D. (2021). Adapting a Low-threshold buprenorphine program for vulnerable populations during the COVID-19 pandemic. Journal of Addiction Medicine, 15(5), 364–369. https://doi.org/10.1097/adm.0000000000000774
   PubMed Web of Science ®Google Scholar
• Pergolizzi, J. V., Raffa, R. B., & Rosenblatt, M. H. (2020). Opioid withdrawal symptoms, a consequence of chronic opioid use and opioid use disorder: Current understanding and approaches to management. Journal of Clinical Pharmacy and Therapeutics, 45(5), 892–903. https://doi.org/10.1111/jcpt.13114
   PubMed Web of Science ®Google Scholar
• Phillips, K. T. (2016). Barriers to practicing risk reduction strategies among people who inject drugs. Addiction Research & Theory, 24(1), 62–68. https://doi.org/10.3109/16066359.2015.1068301
   PubMed Web of Science ®Google Scholar
• Platt, L., Minozzi, S., Reed, J., Vickerman, P., Hagan, H., French, C., Jordan, A., Degenhardt, L., Hope, V., Hutchinson, S., Maher, L., Palmateer, N., Taylor, A., Bruneau, J., & Hickman, M. (2017). Needle syringe programmes and opioid substitution therapy for preventing hepatitis C transmission in people who inject drugs. The Cochrane Database of Systematic Reviews, 9(9), CD012021. https://doi.org/10.1002/14651858.CD012021.pub2
   PubMed Web of Science ®Google Scholar
• Pollini, R. A., Paquette, C. E., Drvar, T., Marshalek, P., Ang-Rabanes, M., Feinberg, J., & Haut, M. W. (2021). A qualitative assessment of discharge against medical advice among patients hospitalized for injection-related bacterial infections in West Virginia. The International Journal on Drug Policy, 94, 103206. https://doi.org/10.1016/j.drugpo.2021.103206
   PubMed Web of Science ®Google Scholar
• Rhodes, T. (2009). Risk environments and drug harms: A social science for harm reduction approach. The International Journal on Drug Policy, 20(3), 193–201. https://doi.org/10.1016/j.drugpo.2008.10.003
   PubMed Web of Science ®Google Scholar
• Rhodes, T., & Treloar, C. (2008). The social production of hepatitis C risk among injecting drug users: A qualitative synthesis. Addiction (Abingdon, England), 103(10), 1593–1603. https://doi.org/10.1111/j.1360-0443.2008.02306.x
   PubMed Web of Science ®Google Scholar
• Ross, M. W., Wodak, A., Stowe, A., & Gold, J. (1994). Explanations for sharing injection equipment in injecting drug users and barriers to safer drug use. Addiction (Abingdon, England), 89(4), 473–479. https://doi.org/10.1111/j.1360-0443.1994.tb00928.x
   PubMed Web of Science ®Google Scholar
• Samuels, E. A., Clark, S. A., Wunsch, C., Jordison Keeler, L. A., Reddy, N., Vanjani, R., & Wightman, R. S. (2020). Innovation During COVID-19: Improving Addiction Treatment Access. Journal of Addiction Medicine, 14(4), e8–e9. https://doi.org/10.1097/adm.0000000000000685
   PubMed Web of Science ®Google Scholar
• Saxon, A. J., Hser, Y.-I., Woody, G., & Ling, W. (2013). Medication-assisted treatment for opioid addiction: Methadone and buprenorphine. Journal of Food and Drug Analysis, 21(4), S69–S72. https://doi.org/10.1016/j.jfda.2013.09.037
   PubMedGoogle Scholar
• Srivastava, A. B., Mariani, J. J., & Levin, F. R. (2020). New directions in the treatment of opioid withdrawal. Lancet (London, England), 395(10241), 1938–1948. https://doi.org/10.1016/s0140-6736(20)30852-7
   PubMed Web of Science ®Google Scholar
• Stein, M. D., Dubyak, P., Herman, D., & Anderson, B. J. (2007). Perceived barriers to safe-injection practices among drug injectors who remain HCV-negative. The American Journal of Drug and Alcohol Abuse, 33(4), 517–525. https://doi.org/10.1080/00952990701407298
   PubMed Web of Science ®Google Scholar
• Strathdee, S. A., Hallett, T. B., Bobrova, N., Rhodes, T., Booth, R., Abdool, R., & Hankins, C. A. (2010). HIV and risk environment for injecting drug users: The past, present, and future. Lancet (London, England), 376(9737), 268–284. https://doi.org/10.1016/s0140-6736(10)60743-x
   PubMed Web of Science ®Google Scholar
• Sullivan, L. E., Metzger, D. S., Fudala, P. J., & Fiellin, D. A. (2005). Decreasing international HIV transmission: The role of expanding access to opioid agonist therapies for injection drug users. Addiction (Abingdon, England), 100(2), 150–158. https://doi.org/10.1111/j.1360-0443.2004.00963.x
   PubMed Web of Science ®Google Scholar
• Summers, P. J., Hellman, J. L., MacLean, M. R., Rees, V. W., & Wilkes, M. S. (2018). Negative experiences of pain and withdrawal create barriers to abscess care for people who inject heroin. A mixed methods analysis. Drug and Alcohol Dependence, 190, 200–208. https://doi.org/10.1016/j.drugalcdep.2018.06.010
   PubMed Web of Science ®Google Scholar
• Ti, L., Milloy, M.-J., Buxton, J., McNeil, R., Dobrer, S., Hayashi, K., Wood, E., & Kerr, T. (2015). Factors associated with leaving hospital against medical advice among people who use illicit drugs in Vancouver, Canada. PloS One, 10(10), e0141594. https://doi.org/10.1371/journal.pone.0141594
   PubMed Web of Science ®Google Scholar
• Tsui, J. I., Burt, R., Thiede, H., & Glick, S. N. (2018). Utilization of buprenorphine and methadone among opioid users who inject drugs. Substance Abuse, 39(1), 83–88. https://doi.org/10.1080/08897077.2017.1363844
   PubMed Web of Science ®Google Scholar
• Weller, S. C., Vickers, B., Bernard, H. R., Blackburn, A. M., Borgatti, S., Gravlee, C. C., & Johnson, J. C. (2018). Open-ended interview questions and saturation. PloS One, 13(6), e0198606. https://doi.org/10.1371/journal.pone.0198606
   PubMed Web of Science ®Google Scholar
• Wright, N. M. J., Tompkins, C. N. E., & Jones, L. (2005). Exploring risk perception and behaviour of homeless injecting drug users diagnosed with hepatitis C. Health & Social Care in the Community, 13(1), 75–83. https://doi.org/10.1111/j.1365-2524.2005.00552.x
   PubMed Web of Science ®Google Scholar
• Zibbell, J. E., Asher, A. K., Patel, R. C., Kupronis, B., Iqbal, K., Ward, J. W., & Holtzman, D. (2018). Increases in acute hepatitis C virus infection related to a growing opioid epidemic and associated injection drug use, United States, 2004 to 2014. American Journal of Public Health, 108(2), 175–181. https://doi.org/10.2105/AJPH.2017.304132
   PubMed Web of Science ®Google Scholar
• Zinberg, N. (1984). Drug, set, and setting: The basis for controlled intoxicant use. Yale University Press.
   Google Scholar