An evaluation of tocotrienol ethosomes for transdermal delivery using Strat-M^® membrane and excised human skin

References

• Aggarwal BB, Kumar A, Bharti AC. 2003. Anticancer potential of curcumin: preclinical and clinical studies. Anticancer Res. 23(1A):363–398.
   PubMed Web of Science ®Google Scholar
• Ahad A, Aqil M, Kohli K, Sultana Y, Mujeeb M. 2013. Enhanced transdermal delivery of an anti-hypertensive agent via nanoethosomes: statistical optimization, characterization and pharmacokinetic assessment. Int J Pharm. 443(1–2):26–38.
   PubMed Web of Science ®Google Scholar
• Alqahtani S, Alayoubi A, Nazzal S, Sylvester PW, Kaddoumi A. 2013. Nonlinear absorption kinetics of self-emulsifying drug delivery systems (SEDDS) containing tocotrienols as lipophilic molecules: in vivo and in vitro studies. AAPS J. 15(3):684–695.
   PubMed Web of Science ®Google Scholar
• Alqahtani S, Alayoubi A, Nazzal S, Sylvester PW, Kaddoumi A. 2014. Enhanced solubility and oral bioavailability of γ-tocotrienol using a self-emulsifying drug delivery system (SEDDS). Lipids. 49(8):819–829.
   PubMed Web of Science ®Google Scholar
• Andrews SN, Jeong E, Prausnitz MR. 2013. Transdermal delivery of molecules is limited by full epidermis, not just stratum corneum. Pharm Res. 30(4):1099–1109.
   PubMed Web of Science ®Google Scholar
• Avadhani KS, Manikkath J, Tiwari M, Chandrasekhar M, Godavarthi A, Vidya SM, Hariharapura RC, Kalthur G, Udupa N, Mutalik S. 2017. Skin delivery of epigallocatechin-3-gallate (EGCG) and hyaluronic acid loaded nano-transfersomes for antioxidant and anti-aging effects in UV radiation induced skin damage. Drug Deliv. 24(1):61–74.
   PubMed Web of Science ®Google Scholar
• Barry BW. 2001. Novel mechanisms and devices to enable successful transdermal drug delivery. Eur J Pharm Sci. 14(2):101–114.
   PubMed Web of Science ®Google Scholar
• Brownlow B, Nagaraj VJ, Nayel A, Joshi M, Elbayoumi T. 2015. Development and in vitro evaluation of vitamin E-enriched nanoemulsion vehicles loaded with genistein for chemoprevention against UVB-induced skin damage. J Pharm Sci. 104(10):3510–3523.
   PubMed Web of Science ®Google Scholar
• Dayan N, Touitou E. 2000. Carriers for skin delivery of trihexyphenidyl HCl: ethosomes vs. liposomes. Biomaterials. 21(18):1879–1885.
   PubMed Web of Science ®Google Scholar
• Dubey V, Mishra D, Dutta T, Nahar M, Saraf D, Jain N. 2007. Dermal and transdermal delivery of an anti-psoriatic agent via ethanolic liposomes. J Control Release. 123(2):148–154.
   PubMed Web of Science ®Google Scholar
• Eaton P, Quaresma P, Soares C, Neves C, de Almeida MP, Pereira E, West P. 2017. A direct comparison of experimental methods to measure dimensions of synthetic nanoparticles. Ultramicroscopy. 182:179–190.
   PubMed Web of Science ®Google Scholar
• Fang Y-P, Tsai Y-H, Wu P-C, Huang Y-B. 2008. Comparison of 5-aminolevulinic acid-encapsulated liposome versus ethosome for skin delivery for photodynamic therapy. Int J Pharm. 356(1–2):144–152.
   PubMed Web of Science ®Google Scholar
• Freitas C, Müller RH. 1998. Effect of light and temperature on zeta potential and physical stability in solid lipid nanoparticle (SLN™) dispersions. Int J Pharm. 168(2):221–229.
   Web of Science ®Google Scholar
• Haq A, Dorrani M, Goodyear B, Joshi V, Michniak-Kohn B. 2018. Membrane properties for permeability testing: skin versus synthetic membranes. Int J Pharm. 539(1–2):58–64.
   PubMedGoogle Scholar
• Hasan ZAA, Idris Z, Gani S, Basri M. 2018. In vitro safety evaluation of palm tocotrienol-rich fraction nanoemulsions for topical application. J Oil Palm Res. 30:150–162.
   Web of Science ®Google Scholar
• Heeremans JL, Gerritsen HR, Meusen SP, Mijnheer FW, Gangaram Panday RS, Prevost R, Kluft C, Crommelin DJ. 1995. The preparation of tissue-type Plasminogen Activator (t-PA) containing liposomes: entrapment efficiency and ultracentrifugation damage. J Drug Target. 3(4):301–310.
   PubMed Web of Science ®Google Scholar
• Jose A, Labala S, Ninave KM, Gade SK, Venuganti VVK. 2018. Effective skin cancer treatment by topical co-delivery of curcumin and STAT3 siRNA using cationic liposomes. AAPS PharmSciTech. 19(1):166–175.
   PubMed Web of Science ®Google Scholar
• Kohli AK, Alpar HO. 2004. Potential use of nanoparticles for transcutaneous vaccine delivery: effect of particle size and charge. Int J Pharm. 275(1–2):13–17.
   PubMed Web of Science ®Google Scholar
• Ling MT, Luk SU, Al-Ejeh F, Khanna KK. 2012. Tocotrienol as a potential anticancer agent. Carcinogenesis. 33(2):233–239.
   PubMed Web of Science ®Google Scholar
• Liu D, Hu H, Lin Z, Chen D, Zhu Y, Hou S, Shi X. 2013. Quercetin deformable liposome: preparation and efficacy against ultraviolet B induced skin damages in vitro and in vivo. J Photochem Photobiol B. 127:8–17.
   PubMed Web of Science ®Google Scholar
• Manickam B, Sreedharan R, Chidambaram K. 2019. Drug/vehicle impacts and formulation centered stratagems for enhanced transdermal drug permeation, controlled release and safety: unparalleled past and recent innovations-an overview. Curr Drug Ther. 14(3):192–209.
   Web of Science ®Google Scholar
• Marto J, Vitor C, Guerreiro A, Severino C, Eleutério C, Ascenso A, Simões S. 2016. Ethosomes for enhanced skin delivery of griseofulvin. Colloids Surf B Biointerfaces. 146:616–623.
   PubMed Web of Science ®Google Scholar
• Mba OI, Dumont M-J, Ngadi M. 2015. Palm oil: processing, characterization and utilization in the food industry – a review. Food Biosci. 10:26–41.
   Web of Science ®Google Scholar
• Nainwal N, Jawla S, Singh R, Saharan VA. 2019. Transdermal applications of ethosomes - a detailed review. J Liposome Res. 29(2):103–113.
   PubMed Web of Science ®Google Scholar
• Nair RS, Morris A, Billa N, Leong C-O. 2019. An evaluation of curcumin-encapsulated chitosan nanoparticles for transdermal delivery. AAPS PharmSciTech. 20(2):69.
   PubMed Web of Science ®Google Scholar
• Nair RS, Nair S. 2015. Permeation studies of captopril transdermal films through human cadaver skin. Curr Drug Deliv. 12(5):517–523.
   PubMed Web of Science ®Google Scholar
• Nzai JM, Proctor A. 1998. Determination of phospholipids in vegetable oil by Fourier transform infrared spectroscopy. J Amer Oil Chem Soc. 75(10):1281–1289.
   Web of Science ®Google Scholar
• Ogiso T, Yamaguchi T, Iwaki M, Tanino T, Miyake Y. 2001. Effect of positively and negatively charged liposomes on skin permeation of drugs. J Drug Targeting. 9(1):49–59.
   PubMed Web of Science ®Google Scholar
• Pandey V, Golhani D, Shukla R. 2015. Ethosomes: versatile vesicular carriers for efficient transdermal delivery of therapeutic agents. Drug Deliv. 22(8):988–1002.
   PubMed Web of Science ®Google Scholar
• Pathan IB, Jaware BP, Shelke S, Ambekar W. 2018. Curcumin loaded ethosomes for transdermal application: formulation, optimization, in-vitro and in-vivo study. J Drug Delivery Sci Technol. 44:49–57.
   Web of Science ®Google Scholar
• Pham J, Nayel A, Hoang C, Elbayoumi T. 2016. Enhanced effectiveness of tocotrienol-based nano-emulsified system for topical delivery against skin carcinomas. Drug Deliv. 23(5):1514–1524.
   PubMed Web of Science ®Google Scholar
• Potts RO, Guy RH. 1992. Predicting skin permeability. Pharm Res. 9(5):663–669.
   PubMed Web of Science ®Google Scholar
• Ruela ALM, Perissinato AG, Lino MEdS, Mudrik PS, Pereira GR. 2016. Evaluation of skin absorption of drugs from topical and transdermal formulations. Braz J Pharm Sci. 52(3):527–544.
   Web of Science ®Google Scholar
• Sapra B, Jindal M, Tiwary AK. 2012. Tight junctions in skin: new perspectives. Ther Deliv. 3(11):1297–1327.
   PubMedGoogle Scholar
• Scolari IR, Páez PL, Sánchez-Borzone ME, Granero GE. 2019. Promising chitosan-coated alginate-tween 80 nanoparticles as rifampicin coadministered ascorbic acid delivery carrier against Mycobacterium tuberculosis. AAPS PharmSciTech. 20(2):67.
   PubMed Web of Science ®Google Scholar
• Silva R, Ferreira H, Little C, Cavaco-Paulo A. 2010. Effect of ultrasound parameters for unilamellar liposome preparation. Ultrason Sonochem. 17(3):628–632.
   PubMed Web of Science ®Google Scholar
• Singh I, Nair RS, Gan S, Cheong V, Morris A. 2019. An evaluation of crude palm oil (CPO) and tocotrienol rich fraction (TRF) of palm oil as percutaneous permeation enhancers using full-thickness human skin. Pharm Dev Technol. 24(4):448–454.
   PubMed Web of Science ®Google Scholar
• Touitou E, Dayan N, Bergelson L, Godin B, Eliaz M. 2000. Ethosomes - novel vesicular carriers for enhanced delivery: characterization and skin penetration properties. J Control Release. 65(3):403–418.
   PubMed Web of Science ®Google Scholar
• Verma P, Pathak K. 2010. Therapeutic and cosmeceutical potential of ethosomes: an overview. J Adv Pharm Technol Res. 1(3):274–282.
   PubMedGoogle Scholar
• Verma P, Pathak K. 2012. Nanosized ethanolic vesicles loaded with econazole nitrate for the treatment of deep fungal infections through topical gel formulation. Nanomedicine. 8(4):489–496.
   PubMed Web of Science ®Google Scholar
• Verma DD, Verma S, Blume G, Fahr A. 2003. Particle size of liposomes influences dermal delivery of substances into skin. Int J Pharm. 258(1–2):141–151.
   PubMed Web of Science ®Google Scholar
• Williams AC, Barry BW. 2004. Penetration enhancers. Adv Drug Deliv Rev. 56(5):603–618.
   PubMed Web of Science ®Google Scholar
• Xie J, Ji Y, Xue W, Ma D, Hu Y. 2018. Hyaluronic acid-containing ethosomes as a potential carrier for transdermal drug delivery. Colloids Surf B Biointerfaces. 172:323–329.
   PubMed Web of Science ®Google Scholar
• Yamaguchi K, Mitsui T, Aso Y, Sugibayashi K. 2008. Structure-permeability relationship analysis of the permeation barrier properties of the stratum corneum and viable epidermis/dermis of rat skin. J Pharm Sci. 97(10):4391–4403.
   PubMed Web of Science ®Google Scholar
• Yang L, Wu L, Wu D, Shi D, Wang T, Zhu X. 2017. Mechanism of transdermal permeation promotion of lipophilic drugs by ethosomes. Int J Nanomed. 12:3357–3364.
   PubMed Web of Science ®Google Scholar
• Yu X, Du L, Li Y, Fu G, Jin Y. 2015. Improved anti-melanoma effect of a transdermal mitoxantrone ethosome gel. Biomed Pharmacother. 73:6–11.
   PubMed Web of Science ®Google Scholar
• Zhai Y, Xu R, Wang Y, Liu J, Wang Z, Zhai G. 2015. Ethosomes for skin delivery of ropivacaine: preparation, characterization and ex vivo penetration properties. J Liposome Res. 25(4):316–324.
   PubMed Web of Science ®Google Scholar