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Letters

Efficiency of siRNA for removal of transthyretin V30M in a TTR leptomeningeal animal model

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Pages 38-39 | Received 12 Oct 2016, Accepted 12 Dec 2016, Published online: 22 Apr 2017

References

  • Santos SD, Fernandes R, Saraiva MJ. The heat shock response modulates transthyretin deposition in the peripheral and autonomic nervous systems. Neurobiol Aging 2010;31:280–9.
  • Butler JS, Chan A, Costelha S, Fishman S, Willoughby JLS, Borland TD, Milstein S, et al. Preclinical evaluation of RNAi as a treatment for transthyretin-mediated amyloidosis. Amyloid 2016;31:1–10.
  • Maia LF, Magalhães R, Freitas J, Taipa R, Pires MM, Osório H, Dias D, et al. CNS involvement in V30M transthyretin amyloidosis: clinical, neuropathological and biochemical findings. J Neurol Neurosurg Psychiatry 2015;86:159–67.

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