A bifunctional peptide, “peptope”, for pre-targeting antibody 7D8 to systemic amyloid deposits

Jonathan S. WallDepartment of Medicine, and ;Department of Radiology, University of Tennessee Medical Center, Knoxville, TN, USA, and Correspondence[email protected]

Angela WilliamsDepartment of Medicine, and

James S. FosterDepartment of Medicine, and

Emily B. MartinDepartment of Medicine, and

Tina RicheyDepartment of Medicine, and

Alan StuckeyDepartment of Medicine, and

Sallie MacyDepartment of Medicine, and

Wagner ZagoProthena Biosciences, San Francisco, CA, USA

Gene G. KinneyProthena Biosciences, San Francisco, CA, USA

Stephen J. KennelDepartment of Medicine, and ;Department of Radiology, University of Tennessee Medical Center, Knoxville, TN, USA, and

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References

Gertz MA, Landau H, Comenzo RL, Seldin D, Weiss B, Zonder J, Merlini G, et al. First-in-human phase I/II study of NEOD001 in patients with light chain amyloidosis and persistent organ dysfunction. J Clin Oncol 2016;34:1097–103.
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Langer AL, Miao S, Mapara M, Radhakrishnan J, Maurer MS, Raza S, Mearset JG, et al. Results of phase i study of chimeric fibril-reactive monoclonal antibody 11-1f4 in patients with AL amyloidosis. Blood 2015;126:188.
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A bifunctional peptide, “peptope”, for pre-targeting antibody 7D8 to systemic amyloid deposits

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A bifunctional peptide, “peptope”, for pre-targeting antibody 7D8 to systemic amyloid deposits

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