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Letters

Probing the structural requirements of polybasic peptides for effective and specific amyloid reactivity

, , , , , , , & show all
Pages 30-31 | Received 15 Nov 2016, Accepted 13 Feb 2017, Published online: 22 Apr 2017

References

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  • Wall JS, Martin EB, Richey T, Stuckey AC, Macy S, Wooliver C, Williams A, et al. Preclinical validation of the heparin-reactive peptide p5 + 14 as a molecular imaging agent for visceral amyloidosis. Molecules 2015;20:7657–82
  • Wall JS, Williams A, Wooliver C, Martin EB, Cheng X, Heidel RE, Kennel SJ. Secondary structure propensity and chirality of the amyloidophilic peptide p5 and its analogues impacts ligand binding - In vitro characterization. Biochem Biophys Rep 2016;8:89–99
  • Lührs T, Ritter C, Adrian M, Riek-Loher D, Bohrmann B, Döbeli H, Schubert D, et al. 3D structure of Alzheimer's amyloid-beta(1-42) fibrils. Proc Natl Acad Sci USA 2005;102:17342–7

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