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Amyloid
The Journal of Protein Folding Disorders
Volume 25, 2018 - Issue 4
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Articles

A pilot study demonstrating cardiac uptake with 18F-florbetapir PET in AL amyloidosis patients with cardiac involvement

Richa ManwaniNational Amyloidosis Centre, University College London (Royal Free Campus), London, UK;
,
Jo PageDepartment of Nuclear Medicine, Royal Free Hospital, London, UK;
,
Thirusha LaneNational Amyloidosis Centre, University College London (Royal Free Campus), London, UK;
,
Maria BurnistonDepartment of Nuclear Medicine, Barts Health NHS Trust, London, UK
,
Annah SkillenDepartment of Nuclear Medicine, Royal Free Hospital, London, UK;
,
Helen J. LachmannNational Amyloidosis Centre, University College London (Royal Free Campus), London, UK;
,
Julian D. GillmoreNational Amyloidosis Centre, University College London (Royal Free Campus), London, UK;
,
Marianna FontanaNational Amyloidosis Centre, University College London (Royal Free Campus), London, UK;
,
Carol WhelanNational Amyloidosis Centre, University College London (Royal Free Campus), London, UK;
,
Philip N. HawkinsNational Amyloidosis Centre, University College London (Royal Free Campus), London, UK;
,
Thomas WagnerDepartment of Nuclear Medicine, Royal Free Hospital, London, UK;
&
Ashutosh D. WechalekarNational Amyloidosis Centre, University College London (Royal Free Campus), London, UK; Correspondence[email protected]
 show all
Pages 247-252 | Received 25 May 2018, Accepted 22 Nov 2018, Published online: 19 Jan 2019

References

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  • Park MA, Padera RF, Belanger A, et al. 18F-Florbetapir binds specifically to myocardial light chain and transthyretin amyloid deposits: autoradiography study. Circ Cardiovasc Imaging. 2015;8:pii: e002954.
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  • Wagner T, Page J, Burniston M, et al. Extracardiac 18F-florbetapir imaging in patients with systemic amyloidosis: more than hearts and minds. Eur J Nucl Med Mol Imaging. 2018;45:1129–1138.
  • Comenzo RL, Reece D, Palladini G, et al. Consensus guidelines for the conduct and reporting of clinical trials in systemic light-chain amyloidosis. Leukemia. 2012;26:2317–2325.
  • Gertz MA, Comenzo R, Falk RH, et al. Definition of organ involvement and treatment response in immunoglobulin light chain amyloidosis (AL): a consensus opinion from the 10th International Symposium on Amyloid and Amyloidosis, Tours, France, 18-22 April 2004. Am J Hematol. 2005;79:319–328.
  • Dispenzieri A, Gertz MA, Kyle RA, et al. Serum cardiac troponins and N-terminal pro-brain natriuretic peptide: a staging system for primary systemic amyloidosis. Jco. 2004;22:3751–3757.
  • Wells K, Osborne D, Stuckey A, et al. 18F Florbetapir PET/CT cardiac amyloid imaging in patients with systemic amyloidosis. J Nucl Med. 2013;54:294.

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