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Paper: Biomarkers of Susceptibility

Association of metabolic gene polymorphisms with alcohol consumption in controls

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Pages 180-189 | Received 09 Apr 2004, Accepted 28 May 2004, Published online: 22 Jan 2010

References

  • BADGER, T M., HUANG, J., RONIS, M. and LUMPKIN, C. K 1993, Induction of cytochrome P450 2E1 during chronic ethanol exposure occurs via transcription of the CYP2E1 gene when blood alcohol concentration are high. Biochemical and Biophysical Research Communications, 190, 780–785.
  • BoRRAs, E., COUTELI-E, C., ROSELL, A., FERNANDEZ-MUIXI, F., BROCH, M., CROSAS, B., HJELMQUIST, L., LORENZO, A., GUTIERREZ, C., SANTOS, M., SZCZEPANEK, M., HEILIG, M., QUATTROCCHI, P., FARRES, J., VIDAL, F., RICHART, C., MACH, T, BOGDAL, J., JORNVALL, H., SEITZ, H. K, COUZIGOU, P. and PARES, X. 2000, Genetic polymorphism of alcohol dehydrogenase in Europeans: the ADH2*2 allele decreases the risk for alcoholism and is associated with ADH3*1. Hepatology, 31, 984–989.
  • BOSRON, W. F., EHRIG, T. and Li, T.-K 1993, Genetic factors in alcohol metabolism and alcoholism. Seminars in Liver Disease, 13, 126–135.
  • BOTJCHARDY, C., HIRVONEN, A., COUTELI-E, C., WARD, P. J., DAYER, P. and BENHAMOU, S. 2000, Role of alcohol dehydrogenase 3 and cytochrome P-4502E1 genotypes in susceptibility to cancers of the upper aerodigestive tract. International Journal of Cancer, 87, 734–740.
  • CAI, L., Yu, S. Z. and ZHAN, Z. F. 2001, Cytochrome P450 2E1 genetic polymorphism and gastric cancer in Changle, Fujian Province. World Journal of Gastroenterology, 7, 792–795.
  • CARER, A., ANDREA011, C., GALATI, R, LEOPARDI, P., MARCON, F., ROSATI, M. V, ROSSI, S., TOMEI, F., VERDINA, A., ZIJNO, A. and CREBELLI, R 2002, Biomonitoring of exposure to urban air pollutants: analysis of sister chromatid exchanges and DNA lesions in peripheral lymphocytes of traffic policemen. Mutation Research, 518, 215–224.
  • CHEN, H., Lum, A., SEIFRIED, A., WILKENS, L. R and LE MARCHAND, L. 1999, Association of the NAD(P)H: quinone oxidoreductase 609C -> T polymorphism with a decreased lung cancer risk. Cancer Research, 59, 3045–3048.
  • CHEN, W. J., Lox, E. W, Hsu, Y.-P. P., CHEN, C-C., Yu, J.-M. and CHENG, A. T. A. 1996, Alcohol-metabolising genes and alcoholism among Taiwanese Han men: independent effect of ADH2, ADH3 and ALDH2. British Journal of Psychiatry, 168, 762–767.
  • CHEN, W. J., Lox, E. W, Hsu, Y-P. P. and CHENG, A. T. A. 1997, Alcohol dehydrogenase and aldehyde dehydrogenase genotypes and alcoholism among Taiwanese Aborigines. Biological Psychiatry, 41, 703–709.
  • CRABS, D. W, DIPPLE, K M. and THOMASSON, H. R. 1993, Alcohol sensitivity, alcohol metabolism, risk of alcoholism, and the role of alcohol and aldehyde dehydrogenase genotypes. Journal of Laboratory and Clinical Medicine, 122, 234–240.
  • GARTE, S., GASPARI, L, ALExANDRIE, A-K., AMBROSONE, C., AUTRUP, H., AUTRUP, J. L., BARANOVA, H., BATHUM, L., BENHAMOU, S., BOFFETTA, P., BOUCHARDY, C., BRESKVAR, K., BROCKMOL-LER, J., CASCORBI, I., CLAPPER, M. L., COUTELI-E, C., DALY, A., DELL'Omo, M., DOLZAN, V., DRESLER, C. M., FRYER, A., HAUGEN, A., HEIN, D. VV., HILDESHEIM, A., HIRVONEN, A., HSIEH, L.-L., INGELMAN-SUNDBERG, M., KALINA, I., KANG, D., KIHARA, M., KIYOHARA, C., KREMERS, P., LAZARUS, P., LE MARCHAND, L., LECIINER, M. C., VAN LIESHOUT, E. M. M., LONDON, S., MANNI, J. J., MAUGARD, C. M., MORITA, S., NAZAR-STEWART, V, NODA, K., ODA, Y., PARE, F. F., PASTORELLS, R., PERSSON, I., PETERS, W. H. M., RANNUG, A., REBBECK, T., RISCH, A., ROELANDT, L., ROMKES, M., RYBERG, D., SALAGOVIC, J., SCHOKET, B., SELDEGARD, J., SHIELDS, P. G., Sim, E., SLNNET, D., STRANGE, R C., STRUCKER, I., STJGIMTJRA, H., TO-FIGUERAS, J., VINEIS, P., Yu, M. C. ad TATOU, E. 2001, Metabolic gene polymorphism frequencies in control populations. Cancer Epidemiology. Biomarkersand Prevention, 10, 1239–1248.
  • GROPPI, A., CourELLE, C., FLEURY, B., IRON, A., BEGUERET, J. and COUZIGOU, P. 1991, Glutathione 5-transferase class n in French alcoholic cirrhotic patients. Human Genetics, 87, 628–630.
  • HARADA, S., AGARWAL, D. P., NOMURA, F. and HIGUCHI, 5.2001, Metabolic and ethnic determinants of alcohol drinking habits and vulnerability to alcohol-related disorder. Alcoholism: Clinical and Experimental Research, 25, 71S–75S.
  • HARTY, L. C., CAPORASO, N. E., HAYES, R. B., Wm, D. M., BRAVO-OTERO, E., BLOT, W. J., KLEINMAN, D. V, BROWN, L M., ARMENIAN, H. K., FRAUMENI, J. F. and SHIELDS, P. G. 1997, Alcohol dehydrogenase 3 genotype and risk of oral cavity and pharyngeal cancers. Journal of the National Cancer Institute, 89, 1698–1705.
  • HAYASHI, S., WATANABE, J. and KAWAJIRI, K. 1991, Genetic polymorphisms in the 5'-flanking region change transcriptional regulation of the human cytochrome P450 IlE1 gene. Journal of Biochemistry (Tokyo), 110, 559–565.
  • HEATH, A. C., Bucnotz, K. K, MADDEN, P. A., DINWIDDIE, S. H., SEursKE, W. S., BEIRUT, D. J., STATHAN, D. J., DONNE, M. P., WiirrnEED, J. B. and MARTIN, N. G. 1997, Genetic and environmental contributions to alcohol dependence risk in a national twin sample: consistency of findings in women and men. Psychological Medicine, 27, 1381–1384.
  • HIGTJCHI, S., MTJRAMATSU, T, MATSUSHITA, S., MURAYAMA, M. and HAYASHLDA, M. 1996, Polymorphism of ethanol-oxidizing enzymes in alcoholics with inactive ALDH2. Human Genetics, 97, 431–434.
  • ITOGA, S., HARADA, S. and NOMURA, F. 2001, Polymorphism of the 5'-flanking region of the CYP2E1 gene: an association study with alcoholism. Alcoholism: Clinical and Experimental Research, 25, 11S–15S.
  • IWAHASHI, K., AMENO, S., AMANO, K, OKADA, N., KINOSHITA, H., SAKAE, Y., NAKAMURA, K, WATANABE, M., IJIRI, I. and HARADA, S. 1998, Relationship between alcoholism and CYP2E1 Cl D polymorphism. Neuropsychobiology, 38, 218–221.
  • IWAHASHI, K., NAKAMURA, K., Suwmu, H., MATSU°, Y. and ORnvo, K. 1993, Contribution of the ALDH2 and CYP2E1 genes to flushing response and drinking patterns in Japanese healthy volunteers. Arukoru Kenkyuto Yakubutsu Ison, 28, 395–399. [in Japanese]
  • KELSEY, K T., Ross, D., TRAVER, R. D., CHRISTIANI, D. C., ZTJO, Z.-F, SPITZ, M. R, WANG, M., XU, X., LEE, B. K, SCHWARTZ, B. S. and WIENCKE, J. K. 1997, Ethnic variation in the prevalence of a common NAD(P)H quinone oxidoreductase polymorphism and its implications for anti-cancer chemotherapy. British Journal of Cancer, 76, 852–854.
  • KENDLER, K S., HEATH, A. C., NEALE, M. C., KESSLER, R C. and EAVENS, L J. 1992, A population-based twin study of alcoholism in women. Journal of the American Medical Association, 268, 1877–1882.
  • KONISHI, T., CAVILS-0, M., LENG, A-S., FENG, J., LEE, T., LEE, H., SMITH, J. L., Sim., S. H., BERMAN, N., FRENCH, S., EYSSELEIN, V, Lm, K.-M. and WAN, Y.-J. Y. 2003, The ADH3*2 and CYP2E1 c2 alleles increase the risk of alcoholism in Mexican American men. Experimental and Molecular Pathology, 74, 183–189.
  • KuNrron, S., IMAOKA, S., HIROI, T, YABUSAKI, Y, MONNA, T. and FUNAE, Y. 1997, Acetaldehyde as well as ethanol is metabolized by human CYP2E1. Journal of Pharmacology and Experimental Therapeutics, 280, 527–532.
  • LE MARCHAND, L., SIVARAMAN, L., PIERCE, L., SEIFRIED, A., Lum, A., WILKENS, L. R. and LAU, A. 1998, Associations of CYP1A1, GSTM1, and CYP2E1 polymorphisms with lung cancer suggest cell type specificities to tobacco carcinogens. Cancer Research, 58, 4858–4863.
  • LEWIS, S. J., CHERRY, N. M., NIVEN, R, BARBER, P. V. and POVEY, A. C. 2001, Polymorphisms in the NAD(P)H: quinone o:cidoreductase gene and small cell lung cancer risk in a UK population. Lung Cancer, 34, 177–183.
  • LIEBER, C. S. 1999, Microsomal ethanol-oxiding system (MEOS): the first 30 years (1968-1988) — a review. Alcoholism: Clinical and Experimental Research, 23, 991–1007.
  • Liu, J., PARK, J. Y., SCHANTZ, S. P., STERN, J. C. and LAZARUS, P. 2001, Elucidation of CYP2E1 5' regulatory RsaIlPstl allelic variants and their role in risk for oral cancer. Oral Oncology, 37, 437–445.
  • MoRrrA, S., Yo, M., TSUJINAKA, T, AKIYAMA, Y, TANIGUCHI, M., KANEKO, K, Mnu, H., Fun', T., YosinNo, K., KUSUOKA, H. and MONDEN, M. 1999, Genetic polymorphisms of drug-metabolizing enzymes and susceptibility to head-and-neck squamous-cell carcinoma. International Journal of Cancer, 80, 685–688.
  • MUNAKA, M., KOHSHI, K, KAWAMOTO, T, TAKASAWA, S., NAGATA, N., ITOH, H., ODA, S. and KATOH, T. 2003, Genetic polymorphisms of tobacco- and alcohol-related metabolizing enzymes and the risk of hepatocellular carcinoma. Journal of Cancer Research and Clinical Oncology, 129, 355–360.
  • NAKAMURA, K, IWAHASHI, K, MATSUO, Y, MIYATAKE, R., ICHIKAWA, Y and Suwpau, H. 1996, Characteristics of Japanese alcoholics with the atypical aldehyde dehydrogenase 2*2. I. A comparison of the genotypes of ALDH2, ADH2, ADH3, and cytochrome P-4502E1 between alcoholics and nonalcoholics. Alcoholism: Clinical and Experimental Research, 20, 52–55.
  • NEUMARK, Y. D., FRIEDLANDER, Y, THOMASSON, H. R and LL T.-K 1997, Association of the ADH2*2 allele with reduced ethanol consumption in Jewish men in Israel: a pilot study. Journal of Studies on Alcohol, 59, 133–139.
  • OKAMOTO, K, MURAWAKI, Y, YUASA, I. and KAWASAKI, H. 2001, Effect of ALDH2 and CYP2E1 gene polymorphisms on drinking behavior and alcoholic liver disease in Japanese male workers. Alcoholism: Clinical and Experimental Research, 25, 19S–23S.
  • OSIER, M., PAKSTIS, A. J., KIDD, J. R, LEE, J.-F., YIN, S.4., Ko, H.-C., EDENBERG, H. J., Lu, R-B. and KIDD, K K. 1998, Linkage disequilibrium at the ADH2 and ADH3 loci and risk of alcoholism. American Journal of Human Genetics, 64, 1147–1157.
  • PASTORELLI, R., BARDAZZI, G., SAIEVA, C., CERRI, A., GESTRI, D., ALLAMANI, A., AIROLDI, L. and PAW, D. 2001, Genetic determinants of alcohol addiction and metabolism: a survey in Italy. Alcoholism: Clinical and Experimental Research, 25, 221–227.
  • Ross, D., TRAVER, R D., SIEGEL, D., KUEHL, B. L, MISRA, V. and RAum, A. M. 1996, A polymorphism in NAD(P)H: quinone oxidoreductase (NQ01): relationship of a homozygous mutation at position 609 of the NQ01 cDNA to NQ01 activity. British Journal of Cancer, 74, 995–996.
  • SUN, F., TsuRrrANL I., HONDA, R, ZHENG-YE, M. and YAMADA, Y. 1999, Association of genetic polymorphisms of alcohol-metabolizing enzymes with excessive alcohol consumption in Japanese men. Human Genetics, 105, 295–300.
  • SUN, F., TsuRrrANL I. and YAMADA, Y. 2002, Contribution of genetic polymorphisms in ethanol-metabolizing enzymes to problem drinking behavior in middle-aged Japanese men. Behavior Genetics, 32, 229–235.
  • TATOU, E. 1999, International Collaborative Study on Genetic Susceptibility to Environmental Carcinogens. Cancer Epidemiology. Biomarkers and Prevention, 8, 727–728.
  • TAKAHASHI, T, LASKER, J. M., ROSMAN, A. S. and LIEBER, C. S. 1993, Induction of cytochrome P-4502E1 in the human liver by ethanol is caused by a corresponding increase in encoding messenger RNA. Hepatology, 17, 236–245.
  • TAMARA, L. W., LUCINDA, G. C. and EHLERS, C. L. 2003, Protective association of genetic variation in alcohol dehydrogenase with alcohol dependence in Native American Mission Indians. American Journal of Psychiatry, 160, 41–46.
  • THOMASSON, H. R., CRABS, D. W, EDEMBERG, H. J. and LL T.-K 1993, Alcohol and aldehyde dehydrogenase polymorphisms and alcoholism. Behavior Genetics, 23, 131–136.
  • THOMASSON, H. R, EDENBERG, H. J., CRABS, D. W., MAL X.-L., JEROME, R E., LL T.-K, WANG, S.-P., Y.-T., Lu, R.-B. and YIN, S.-J. 1991, Alcohol and aldehyde dehydrogenase genotypes and alcoholism in Chinese men. American Journal of Human Genetics, 48, 677–681.
  • TRAVER, R. D., HORIKOSHI, T., DANENBERG, K. D., STADLBATJER, T. H., DANENBERG, P. V., Ross, D. and GIBSON, N. W. 1992, NAD(P)H: quinone oxidoreductase gene expression in human colon carcinoma cells: characterization of a mutation which modulates DT-diaphorase activity and mitomycin sensitivity. Cancer Research, 52, 797–802.
  • Tsu-rsumL M., WANG, J. S., TAKASE, S. and TAKADA, A. 1994, Hepatic messenger RNA contents of cytochrome P4502E1 in patients with different P4502E1 genotypes. Alcohol, 29 (Suppl. 11), 29–32.
  • VAN DIJK, B. A. C., VAN HOUWELINGEN, K P., WI11ES, J. A., SCHALKEN, J. A. and KIEMENEY, L A. L.M. 2001, Alcohol dehydrogenase type 3 (ADH3) and the risk of bladder cancer. European Urology, 40, 509–514.
  • VINEIS, P., MALATS, N., LANG, M., D'ERRIco, A., CAPORASO, N., CuzicK, J. and BoFFErrA, P. 1999, Metabolic Polymorphism and Susceptibility to Cancer (Oxford: Oxford University Press for the IARC).

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