221
Views
0
CrossRef citations to date
0
Altmetric
Original Article

Serum neurofilament light chain in functionally relevant coronary artery disease and adverse cardiovascular outcomes

ORCID Icon, , , , , , , , , , , , , , & show all
Pages 341-351 | Received 06 Sep 2022, Accepted 03 Jan 2023, Published online: 12 Feb 2023

References

  • Aeschbacher, S., et al., 2018. P2908Serum light-chain neurofilament, a brain lesion marker, correlates with CHA2DS2-VASc score among patients with atrial fibrillation: a cross-sectional study. European Heart journal, 39 (suppl_1), ehy565-P2908.
  • Akamine, S., et al., 2020. Renal function is associated with blood neurofilament light chain level in older adults. Scientific reports, 10 (1), 20350.
  • Altmann, P., et al., 2020. Serum neurofilament light chain withstands delayed freezing and repeated thawing. Scientific reports, 10 (1), 19982.
  • Altmann, P., et al., 2021. Seven day pre-analytical stability of serum and plasma neurofilament light chain. Scientific reports, 11 (1), 11034.
  • Barro, C., et al., 2020. Blood neurofilament light: a critical review of its application to neurologic disease. Annals of clinical and translational neurology, 7 (12), 2508–2523.
  • Benkert, P., et al., 2022. Serum neurofilament light chain for individual prognostication of disease activity in people with multiple sclerosis: a retrospective modelling and validation study. The Lancet. Neurology, 21 (3), 246–257.
  • Bossuyt, P.M., et al., 2015. STARD 2015: an updated list of essential items for reporting diagnostic accuracy studies. Clinical chemistry, 61 (12), 1446–1452.
  • Czeiter, E., et al., 2020. Blood biomarkers on admission in acute traumatic brain injury: relations to severity, CT findings and care path in the CENTER-TBI study. EBioMedicine, 56, 102785.
  • DeLong, E.R., et al., 1988. Comparing the areas under two or more correlated receiver operating characteristic curves: a nonparametric approach. Biometrics, 44 (3), 837–845.
  • Devereaux, P.J., 2018. The potential for troponin to inform prognosis in patients with stable coronary artery disease. Annals of internal medicine, 169 (11), 808–809.
  • Disanto, G., et al., 2017. Serum Neurofilament light: A biomarker of neuronal damage in multiple sclerosis. Annals of neurology, 81 (6), 857–870.
  • Falkensammer, J., et al., 2012. Elevated baseline hs-cTnT levels predict exercise-induced myocardial ischemia in patients with peripheral arterial disease. Clinica chimica acta; international journal of clinical chemistry, 413 (19–20), 1678–1682.
  • Hammadah, M., et al., 2018. Use of high-sensitivity cardiac troponin for the exclusion of inducible myocardial ischemia: a cohort study. Annals of internal medicine, 169 (11), 751–760.
  • Hastie, T., et al., 2021. An introduction to glmnet. CRAN R Repositary, 5, 1–35.
  • Hortmann, M., et al., 2019. Droplet digital PCR of serum miR-499, miR-21 and miR-208a for the detection of functionally relevant coronary artery disease. International journal of cardiology, 275, 129–135.
  • Hosmer, D. W., Jr., et al., 2013. Applied logistic regression. Hoboken, NJ: John Wiley & Sons.
  • Jauch, E.C., et al., 2013. Guidelines for the early management of patients with acute ischemic stroke. Stroke, 44 (3), 870–947.
  • Kaeser, S.A., et al., 2021. A neuronal blood marker is associated with mortality in old age. Nature Aging, 1 (2), 218–225.
  • Khalil, M., et al., 2018. Neurofilaments as biomarkers in neurological disorders. Nature reviews. Neurology, 14 (10), 577–589.
  • Khalil, M., et al., 2020. Serum neurofilament light levels in normal aging and their association with morphologic brain changes. Nature communications, 11 (1), 812.
  • Knuuti, J., et al., 2020. 2019 ESC guidelines for the diagnosis and management of chronic coronary syndromes. European heart journal, 41 (3), 407–477.
  • Korley, F.K., et al., 2019. Serum NfL (Neurofilament Light Chain) Levels and Incident Stroke in Adults With Diabetes Mellitus. Stroke, 50 (7), 1669–1675.
  • Krintus, M., et al., 2014. European multicenter analytical evaluation of the Abbott ARCHITECT STAT high sensitive troponin I immunoassay. Clinical chemistry and laboratory medicine, 52 (11), 1657–1665.
  • Ladapo, J.A., et al., 2014. Physician decision making and trends in the use of cardiac stress testing in the United States: an analysis of repeated cross-sectional data. Annals of internal medicine, 161 (7), 482.
  • Lee, G., et al., 2016. Clinical benefit of high-sensitivity cardiac troponin I in the detection of exercise-induced myocardial ischemia. American heart journal, 173, 8–17.
  • Levey, A.S., et al., 2009. A new equation to estimate glomerular filtration rate. Annals of internal medicine, 150 (9), 604–612.
  • Li, Q., et al., 2018. Cerebral small vessel disease. Cell transplantation, 27 (12), 1711–1722.
  • Liu, D., et al., 2020. Serum neurofilament light chain as a predictive biomarker for ischemic stroke outcome: a systematic review and meta-analysis. Journal of stroke and cerebrovascular diseases, 29 (6), 104813.
  • Lucas, F.L., et al., 2006. Temporal trends in the utilization of diagnostic testing and treatments for cardiovascular disease in the United States, 1993\&\#x2013;2001. Circulation, 113 (3), 374–379.
  • Mueller, D., et al., 2018. Direct comparison of Cardiac Troponin T and I using a uniform and a sex-specific approach in the detection of functionally relevant coronary artery disease. Clinical chemistry, 64 (11), 1596–1606.
  • Myhre, P.L., et al., 2018. Cardiac troponin T concentrations, reversible myocardial ischemia, and indices of left ventricular remodeling in patients with suspected stable angina pectoris: a DOPPLER-CIP substudy. Clinical chemistry, 64 (9), 1370–1379.
  • Nielsen, H.H., et al., 2020. Acute neurofilament light chain plasma levels correlate with stroke severity and clinical outcome in ischemic stroke patients. Frontiers in neurology, 11, 448.
  • Olesen, K.K.W., et al., 2017. Coronary artery disease and risk of adverse cardiac events and stroke. European journal of clinical investigation, 47 (11), 819–828.
  • Polymeris, A.A., et al., 2020. Serum neurofilament light in atrial fibrillation: clinical, neuroimaging and cognitive correlates. Brain communications, 2 (2), fcaa166.
  • Preische, O., et al., 2019. Serum neurofilament dynamics predicts neurodegeneration and clinical progression in presymptomatic Alzheimer’s disease. Nature medicine, 25 (2), 277–283.
  • Puelacher, C., et al., 2018. Combining high-sensitivity cardiac troponin and B-type natriuretic peptide in the detection of inducible myocardial ischemia. Clinical biochemistry, 52, 33–40.
  • Qu, Y., et al., 2021. Association of plasma neurofilament light with small vessel disease burden in nondemented elderly. Stroke, 52 (3), 896–904.
  • Røsjø, H., et al., 2012. Troponin I measured by a high-sensitivity assay in patients with suspected reversible myocardial ischemia: data from the Akershus Cardiac Examination (ACE) 1 study. Clinical chemistry, 58 (11), 1565–1573.
  • Sanders, R.D., et al., 2021. Postoperative troponin increases after noncardiac surgery are associated with raised neurofilament light: a prospective observational cohort study. British journal of anaesthesia, 126 (4), 791–798.
  • Shahim, P., et al., 2020. Time course and diagnostic utility of NfL, tau, GFAP, and UCH-L1 in subacute and chronic TBI. Neurology, 95 (6), e623–e636.
  • Tanglay, Y., et al., 2015. Incremental value of a single high-sensitivity cardiac troponin I measurement to rule out myocardial ischemia. The American journal of medicine, 128 (6), 638–646.
  • Thebault, S., et al., 2020. Blood neurofilament light chain: the neurologist’s troponin? Biomedicines, 8 (11), 523.
  • Tveit, S.H., et al., 2021. Differential associations of cardiac troponin T and cardiac troponin I with coronary artery pathology and dynamics in response to short-duration exercise. Clinical biochemistry, 88, 23–29.
  • Uphaus, T., et al., 2019. NfL (neurofilament light chain) levels as a predictive marker for long-term outcome after ischemic stroke. Stroke, 50 (11), 3077–3084.
  • Walter, J., et al., 2019. Clinical utility of circulating interleukin-6 concentrations in the detection of functionally relevant coronary artery disease. International Journal of cardiology, 275, 20–25.
  • Walter, J., et al., 2020. Using high-sensitivity cardiac troponin for the exclusion of inducible myocardial ischemia in symptomatic patients: a cohort study. Annals of internal medicine, 172 (3), 175–185.
  • Walter, J.E., et al., 2018. Prospective validation of a biomarker-based rule out strategy for functionally relevant coronary artery disease. Clinical chemistry, 64 (2), 386–395.
  • Wang, P., et al., 2020. Serum neurofilament light predicts severity and prognosis in patients with ischemic stroke. Neurotoxicity research, 37 (4), 987–995.
  • World Health Organization. 2019. World health statistics overview 2019: Monitoring health for the SDGs, sustainable development goals. World Health Organization, No. WHO/DAD/2019.1.

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.