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Research Articles

Utilizing circulating tumour DNA as a prognostic predictor of gastric cancer: a meta-analysis

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Pages 427-436 | Received 16 Jan 2023, Accepted 05 Apr 2023, Published online: 30 May 2023

References

  • Balgkouranidou, I., et al., 2013. Assessment of SOX17 DNA methylation in cell free DNA from patients with operable gastric cancer. Association with prognostic variables and survival. Clinical chemistry and laboratory medicine, 51 (7), 1505–1510.
  • Balgkouranidou, I., et al., 2015. Prognostic role of APC and RASSF1A promoter methylation status in cell free circulating DNA of operable gastric cancer patients. Mutation research, 778, 46–51.
  • Borggreve, A.S., et al., 2019. Imaging strategies in the management of gastric cancer: current role and future potential of MRI. The british journal of radiology, 92 (1097), 20181044.
  • Bronkhorst, A.J., Ungerer, V., and Holdenrieder, S., 2020. Early detection of cancer using circulating tumor DNA: biological, physiological and analytical considerations. Critical reviews in clinical laboratory sciences, 57 (4), 253–269.
  • Bu, J., et al., 2020. Enhanced detection of cell-free DNA (cfDNA) enables its use as a reliable biomarker for diagnosis and prognosis of gastric cancer. PLoS one, 15 (12), e0242145.
  • Cai, Z., et al., 2020. Detection of microsatellite instability from circulating tumor DNA by targeted deep sequencing. The journal of molecular diagnostics: JMD, 22 (7), 860–870.
  • Căinap, C., et al., 2015. Classic tumor markers in gastric cancer. Current standards and limitations. Clujul medical (1957), 88 (2), 111–115.
  • Chae, Y.K., and Oh, M.S., 2019. Detection of minimal residual disease using ctDNA in lung cancer: current evidence and future directions. Journal of thoracic oncology, 14 (1), 16–24.
  • Chen, X., et al., 2020. Non-invasive early detection of cancer four years before conventional diagnosis using a blood test. Nature communications, 11 (1), 3475.
  • Comprehensive molecular characterization of gastric adenocarcinoma. 2014. Nature, 513 (7517), 202–209.
  • Costa Normando, S.R., et al., 2018. Circulating free plasma tumor DNA in patients with advanced gastric cancer receiving systemic chemotherapy. BMC clinical pathology, 18, 12.
  • Duval, S., and Tweedie, R., 2000. Trim and fill: A simple funnel-plot-based method of testing and adjusting for publication bias in meta-analysis. Biometrics, 56 (2), 455–463.
  • Egger, M., et al., 1997. Bias in meta-analysis detected by a simple, graphical test. BMJ (clinical research ed.), 315 (7109), 629–634.
  • Fang, W.-L., et al., 2016. Clinical significance of circulating plasma DNA in gastric cancer. International journal of cancer, 138 (12), 2974–2983.
  • Fang, W.-L., et al., 2019. Analysis of the clinical significance of DNA methylation in gastric cancer based on a genome-wide high-resolution array. Clinical epigenetics, 11 (1), 154.
  • Faulkner, L.G., et al., 2023. The utility of ctDNA in detecting minimal residual disease following curative surgery in colorectal cancer: a systematic review and meta-analysis. British journal of cancer, 128 (2), 297–309.
  • Gale, D., et al., 2022. Residual ctDNA after treatment predicts early relapse in patients with early-stage non-small cell lung cancer. Annals of oncology, 33 (5), 500–510.
  • Gao, Y., et al., 2017. Diagnostic and prognostic value of circulating tumor DNA in gastric cancer: a meta-analysis. Oncotarget, 8 (4), 6330–6340.
  • Han, J., et al., 2014. Circulating methylated MINT2 promoter DNA is a potential poor prognostic factor in gastric cancer. Digestive diseases and sciences, 59 (6), 1160–1168.
  • Hariharan, R., and Jenkins, M., 2020. Utility of the methylated SEPT9 test for the early detection of colorectal cancer: a systematic review and meta-analysis of diagnostic test accuracy. BMJ open gastroenterology, 7 (1), e000355.
  • Hayden, J.A., et al., 2013. Assessing bias in studies of prognostic factors. Annals of internal medicine, 158 (4), 280–286.
  • He, C.-Z., et al., 2013. Combined use of AFP, CEA, CA125 and CAl9-9 improves the sensitivity for the diagnosis of gastric cancer. BMC gastroenterology, 13 (1), 87.
  • Heitzer, E., Auinger, L., and Speicher, M.R., 2020. Cell-free DNA and apoptosis: how dead cells inform about the living. Trends in molecular medicine, 26 (5), 519–528.
  • Higgins, J.P.T., et al., 2003. Measuring inconsistency in meta-analyses. BMJ (clinical research ed.), 327 (7414), 557–560.
  • Hu, X.-Y., et al., 2021. Circulating methylated THBS1 DNAs as a novel marker for predicting peritoneal dissemination in gastric cancer. Journal of clinical laboratory analysis, 35 (9), e23936.
  • Hu, Y., et al., 2019. Predictive value of the serum RASSF10 promoter methylation status in gastric cancer. The journal of international medical research, 47 (7), 2890–2900.
  • Huang, Y., et al., 2020. A novel nest hybridization chain reaction based electrochemical assay for sensitive detection of circulating tumor DNA. Analytica chimica acta, 1107, 40–47.
  • Japanese Gastric Cancer Association. 2023. Japanese Gastric Cancer Treatment Guidelines 2021 (6th edition). Gastric cancer, 26 (1), 1–25.
  • Jelski, W., et al., 2008. Alcohol dehydrogenase (ADH) isoenzymes and aldehyde dehydrogenase (ALDH) activity in the sera of patients with gastric cancer. Digestive diseases and sciences, 53 (8), 2101–2105.
  • Jelski, W., et al., 2010. The diagnostic value of alcohol dehydrogenase (ADH) isoenzymes and aldehyde dehydrogenase (ALDH) measurement in the sera of gastric cancer patients. Clinical and experimental medicine, 10 (4), 215–219.
  • Jin, Y., et al., 2020. The predicting role of circulating tumor DNA landscape in gastric cancer patients treated with immune checkpoint inhibitors. Molecular cancer, 19 (1), 154.
  • Jogo, T., et al., 2021. Circulating tumor DNA analysis detects FGFR2 amplification and concurrent genomic alterations associated with FGFR inhibitor efficacy in advanced gastric cancer. Clinical cancer research, 27 (20), 5619–5627.
  • Karamitrousis, E.I., et al., 2021. Prognostic role of RASSF1A, SOX17 and Wif-1 promoter methylation status in cell-free DNA of advanced gastric cancer patients. Technology in cancer research & treatment, 20, 1533033820973279–1533033820973279.
  • Kato, S., et al., 2018. Analysis of circulating tumor DNA and clinical correlates in patients with esophageal, gastroesophageal junction, and gastric adenocarcinoma. Clinical cancer research, 24 (24), 6248–6256.
  • Kim, S.S., et al., 2020. MLH1 single-nucleotide variant in circulating tumor DNA predicts overall survival of patients with hepatocellular carcinoma. Scientific reports, 10 (1), 17862.
  • Leal, A., et al., 2020. White blood cell and cell-free DNA analyses for detection of residual disease in gastric cancer. Nature communications, 11 (1), 525.
  • Leon, S., et al., 1977. Free DNA in the serum of cancer patients and the effect of therapy. Cancer research, 37 (3), 646–650.
  • Li, Z., and Guo, Z., 2020. Comparison of CDH1 gene hypermethylation status in blood and serum among gastric cancer patients. Pathology oncology research: POR, 26 (2), 1057–1062.
  • Lim, H.-K., et al., 2013. Disappearance of serum methylated p16 indicates longer survival in patients with gastric cancer. Journal of gastric cancer, 13 (3), 157–163.
  • Lin, X., et al., 2020. Plasma cell-free DNA for screening patients with benefit-assisted neoadjuvant chemotherapy for advanced gastric cancer. ScienceAsia, 46 (4), 462–471.
  • Ling, Z.-Q., et al., 2013. Circulating methylated XAF1 DNA indicates poor prognosis for gastric cancer. PLoS one, 8 (6), e67195.
  • Maron, S.B., et al., 2019. Circulating tumor DNA sequencing analysis of gastroesophageal adenocarcinoma. Clinical cancer research, 25 (23), 7098–7112.
  • Moher, D., et al., 2009. Preferred reporting items for systematic reviews and meta-analyses: the PRISMA statement. BMJ (clinical research ed.), 339, b2535.
  • Oikonomidou, E., Greek General Practice Dyspepsia Group*., et al., 2011. Upper gastrointestinal endoscopy for dyspepsia: Εxploratory study of factors influencing patient compliance in Greece. BMC gastroenterology, 11 (1), 11. and,
  • Openshaw, M.R., et al., 2020. Longitudinal monitoring of circulating tumour DNA improves prognostication and relapse detection in gastroesophageal adenocarcinoma. British journal of cancer, 123 (8), 1271–1279.
  • Page, M.J., et al., 2021. The PRISMA 2020 statement: an updated guideline for reporting systematic reviews. BMJ (clinical research ed.), 372, n71.
  • Parikh, R.B., and Prasad, V., 2016. Blood-based screening for colon cancer: A disruptive innovation or simply a disruption? JAMA, 315 (23), 2519–2520.
  • Peng, H., et al., 2019. CNV detection from circulating tumor DNA in late stage non-small cell lung cancer patients. Genes, 10 (11), 926.
  • Pessoa, L.S., Heringer, M., and Ferrer, V.P., 2020. ctDNA as a cancer biomarker: A broad overview. Critical reviews in oncology/hematology, 155, 103109.
  • Pimson, C., et al., 2016. Aberrant methylation of PCDH10 and RASSF1A genes in blood samples for non-invasive diagnosis and prognostic assessment of gastric cancer. PeerJ, 4, e2112.
  • Rawla, P., and Barsouk, A., 2019. Epidemiology of gastric cancer: global trends, risk factors and prevention. Przeglad gastroenterologiczny, 14 (1), 26–38.
  • Saluja, H., et al., 2018. The use of circulating tumor DNA for prognosis of gastrointestinal cancers. Frontiers in oncology, 8, 275.
  • Schwarzer, G., 2007. meta: An R package for meta-analysis. R news, 7 (3), 40–45.
  • Sexton, R.E., et al., 2020. Gastric cancer: a comprehensive review of current and future treatment strategies. Cancer metastasis reviews, 39 (4), 1179–1203.
  • Smyth, E.C., et al., 2020. Gastric cancer. Lancet (London, England), 396 (10251), 635–648.
  • Smyth, E.C., et al., 2021. EGFR amplification and outcome in a randomised phase III trial of chemotherapy alone or chemotherapy plus panitumumab for advanced gastro-oesophageal cancers. Gut, 70 (9), 1632–1641.
  • Song, L., et al., 2020. Opportunistic screening and survival prediction of digestive cancers by the combination of bloodmSEPT9with protein markers. Therapeutic advances in medical oncology, 12, 175883592096296.
  • Spolverato, G., et al., 2014. Rates and patterns of recurrence after curative intent resection for gastric cancer: a United States multi-institutional analysis. Journal of the American college of surgeons, 219 (4), 664–675.
  • Stroup, D.F., et al., 2000. Meta-analysis of observational studies in epidemiology: a proposal for reporting. Meta-analysis of observational studies in epidemiology (MOOSE) group. JAMA, 283 (15), 2008–2012.
  • Thrift, A.P., and El-Serag, H.B., 2020. Burden of gastric cancer. Clinical gastroenterology and hepatology, 18 (3), 534–542.
  • Tierney, J.F., et al., 2007. Practical methods for incorporating summary time-to-event data into meta-analysis. Trials, 8 (1), 16.
  • van Velzen, M.J.M., et al., 2022. Circulating tumor DNA predicts outcome in metastatic gastroesophageal cancer. Gastric cancer, 25 (5), 906–915.
  • Viechtbauer, W., 2010. Conducting meta-analyses in R with the meta for package. Journal of statistical software, 36 (3), 1–48.
  • Viechtbauer, W., and Cheung, M.W.-L., 2010. Outlier and influence diagnostics for meta-analysis. Research synthesis methods, 1 (2), 112–125.
  • Wang, G., et al., 2015. The diagnosis value of promoter methylation of UCHL1 in the serum for progression of gastric cancer. Biomed research international, 2015, 1–8.
  • Wang, Y., et al., 2019. Circulating tumor DNA analyses predict progressive disease and indicate trastuzumab-resistant mechanism in advanced gastric cancer. EBioMedicine, 43, 261–269.
  • Wong, M.C.S., et al., 2021. Global incidence and mortality of gastric cancer, 1980-2018. JAMA network open, 4 (7), e2118457.
  • Wu, R., et al., 2020. Detection of circulating tumor cell DNA for monitoring advanced gastric cancer. International journal of clinical and experimental pathology, 13 (2), 203–211.
  • Wu, Y.-C., et al., 2014. Enhanced serum methylated p16 DNAs is associated with the progression of gastric cancer. International journal of clinical and experimental pathology, 7 (4), 1553–1562.
  • Xi, W., et al., 2022. Molecular evolutionary process of advanced gastric cancer during sequential chemotherapy detected by circulating tumor DNA. Journal of translational medicine, 20 (1), 365.
  • Xu, R., et al., 2017. Circulating tumour DNA methylation markers for diagnosis and prognosis of hepatocellular carcinoma. Nature materials, 16 (11), 1155–1161.
  • Xue, W.-J., et al., 2016. The value of serum RASSF10 hypermethylation as a diagnostic and prognostic tool for gastric cancer. Tumour biology, 37 (8), 11249–11257.
  • Yan, H., et al., 2021a. Value of plasma methylated SFRP2 in prognosis of gastric cancer. Digestive diseases and sciences, 66 (11), 3854–3861.
  • Yan, Y., et al., 2021b. Cell-free DNA: hope and potential application in cancer. Frontiers in cell and developmental biology, 9, 639233.
  • Yang, J., et al., 2020. Deep sequencing of circulating tumor DNA detects molecular residual disease and predicts recurrence in gastric cancer. Cell death & disease, 11 (5), 346.
  • Yi, X., et al., 2017. The feasibility of using mutation detection in ctDNA to assess tumor dynamics. International journal of cancer, 140 (12), 2642–2647.
  • Yoruker, E.E., et al., 2021. Fragmentation analysis of plasma DNA reveals its prognostic value in gastric cancer. The turkish journal of gastroenterology, 32 (9), 720–726.
  • Yu, J.-L., et al., 2014. Methylated TIMP-3 DNA in body fluids is an independent prognostic factor for gastric cancer. Archives of pathology & laboratory medicine, 138 (11), 1466–1473.
  • Zhang, Z., et al., 2020. Using circulating tumor DNA as a novel biomarker to screen and diagnose hepatocellular carcinoma: a systematic review and meta-analysis. Cancer medicine, 9 (4), 1349–1364.

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