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Research Article

Oxidative Stress, Perturbed Calcium Homeostasis, and Immune Dysfunction in Alzheimer's Disease

Pages 539-550 | Published online: 10 Jul 2009

References

  • Artavanis-Tsakonis S, Matsuno K, Fortini ME (1995). Notch signaling. Science 268: 225–231.
  • Atwood CS, Huang X, Khatri A, Scarpa RC, Kim YS, Moir RD, Tanzi RE, Roher AE, Bush Al (2000). Copper cat-alyzed oxidation of Alzheimer Abeta. Cell Mol Biol 46: 777–783.
  • Baker HF, Ridley RM, Duchen LW, Crow TJ, Bruton CJ (1994). Induction of beta (A4)-amyloid in primates by injection of Alzheimer's disease brain homogenate. Comparison with transmission of spongiform en-cephalop athy. Mol Neurobiol 8: 25–39.
  • Barger SW, Basile AS (2001). Activation of microglia by secreted amyloid precursor protein evokes release of glutamate by cystine exchange and attenuates synaptic function. J Neurochem 76: 846–854.
  • Barger SW, Horster D, Furukawa K, Goodman Y, Krieglstein J, Mattson MP (1995). Tumor necrosis factors alpha and beta protect neurons against amyloid beta-peptide toxi-city: evidence for involvement of a kappa B-binding fac-tor and attenuation of peroxide and Ca2+ accumulation. Proc Nati Acad Sci USA 92: 9328–9332.
  • Barrow PA, Empson RM, Gladwell SJ, Anderson CM, Killick R, Yu X, Jefferys JG, Duff K (2000). Functional phenotype in transgenic mice expressing mutant human presenilin-1. Neurobiol Dis 7: 119–126.
  • Begley JG, Duan W, Chan S, Duff K, Mattson MP (1999). Al-tered calcium homeostasis and mitochondrial dysfunc-tion in cortical synaptic compartments of presenilin-1 mutant mice. J Neurochem 72: 1030–1039.
  • Berridge MJ, Lipp P, Bootman MD (2000). The versatility and universality of calcium signaling, Nat Rev Mol Cell Biol 1: 11–21.
  • Blanc EM, Keller JN, Fernandez S, Mattson MP (1998). 4-Hydroxynonenal, a lipid peroxidation product, im-pairs glutamate transport in cortical astrocytes. Glia 22: 149–160.
  • Bongioanni P, Boccardi B, Borgna M, Castagna M, Mondino C (1997). T-cell interferon gamma binding in patients with dementia of the Alzheimer type. Arch Neurol 54: 457–462.
  • Bongioanni P, Boccardi B, Borgna M, Rossi B (1998). T-lymphocyte interleukin 6 receptor binding in patients with dementia of Alzheimer type. Arch Neurol 55: 1305–1308.
  • Bourguignon LY, Jin H (1995). Identification of the ankyrin-binding domain of the mouse T-lymphoma cell inosi-tol 1,4,5-trisphosphate (IP3) receptor and its role in the regulation of 1P3 -mediated internal Ca2+ release. J Biol Chem 270: 7257–7260.
  • Brillantes AM, Ondrias BK, Scott A, Kobrinsky E, Ondriasova E, Moschella MC, Jararaman T, Landers M, Ehrlich BE, Marks AR (1994). Stabilization of calcium release channel (ryanodine receptor) function by FK-506 binding protein. Cell 77: 513–523.
  • Bruce-Keller AJ, Umberger G, McFall R, Mattson MP (1999). Food restriction reduces brain damage and improves be-havioral outcome following excitotoxic and metabolic insults. Ann Neurol 45: 8–15.
  • Bruunsgaard H, Andersen-Ranberg K, Jeune B, Pedersen AN, Skinhoj P, Pedersen BK (1999). A high plasma con-centration of TNF-alpha is associated with dementia in centenarians. J Gerontol A Biol Sci Med Sci 54: M357–M364.
  • Butterfield DA, Drake J, Pocernich C, Castegna A (2001). Evidence of oxidative damage in Alzheimer's disease brain: central role for amyloid beta-peptide. Trends Mol Med 7: 548–554.
  • Buxbaum JD, Choi EK, Luo Y, Lilliehook C, Crowley AC, Merriam DE, Wasco W (1998). Calsenilin: a calcium-binding protein that interacts with the presenilins and regulates the levels of a presenilin fragment. Nat Med 4: 1177–1181.
  • Cameron AM, Steiner JP, Roskams AJ, Ali SM, Ronnett GV, Snyder SH (1996). Calcineurin associated with the inos-itol 1,4,5-trisphosphate receptor-FKBP12 complex mod-ulates Ca2+ flux. Cell 83: 463–472.
  • Cecchi C, Latorraca S, Sorbi S, Iantomasi T, Favilli F, Vincenzini MT, Liguri G (1999). Gluthatione level is altered in lymphoblasts from patients with familial Alzheimer's disease. Neurosci Lett 275: 152–154.
  • Chan SL, Mayne M, Holden CP, Geiger JD, Mattson MP (2000). Presenilin-1 mutations increase levels of ryanodine receptors and calcium release in PC12 cells and cortical neurons. J Biol Chem 275: 18195–18200.
  • Chittajallu R, Alford S, Collingridge GL (1998). Ca2+ and synaptic plasticity. Cell Calcium 24: 377–385.
  • Conlon RA, Reaume AG, Rossant J (1995). Notch1 is required for the coordinate segmentation of somites. Development 121: 1533–1542.
  • Cruz-Sanchez F, Lafuente J, Figols J, Cervos-Navarro J (1988). Topographic analysis of neuropathologic find-ings in 16 cases of Creutzfeldt-Jacob disease. Arch Neu-robiol (Madr) 51: 191–196.
  • Culmsee C, Zhu Z, Yu QS, Chan SL, Camandola S, Guo Z, Greig N, Mattson MP (2001). A synthetic inhibitor of p53 protects neurons against death induced by ischemic and excitotoxic insults, and amyloid /3-peptide. J Neu-rochem 77: 220–228.
  • D'Adamio L, Lacana E, Vito P (1997). Functional cloning of genes involved in T-cell receptor-induced programmed cell death. Semin Immunol 9: 17–23.
  • DiCarlo G, Wilcock D, Henderson D, Gordon M, Morgan D (2001). Intrahippocampal LPS injections reduce A/3 load in APPH-PS1 transgenic mice. Neurobiol Aging 22: 1007–1012.
  • Duan W, Mattson MP (1999). Dietary restriction and 2-deoxyglucose administration improve behavioral out-come and reduce degeneration of dopaminergic neurons in models of Parkinson's disease. J Neurosci Res 57: 195–206.
  • Eckert A, Forstl H, Zerfass R, Hartmann H, Muller VVE (1996). Lymphocytes and neutrophils as peripheral models to study the effect of beta-amyloid on cellular calcium signalling in Alzheimer's disease. Life Sci 59: 499–510.
  • Eckert A, Schindowski K, Leutner S, Luckhaus C, Touchet N, Czech C, Muller WE (2001). Alzheimer's disease-like alterations in peripheral cells from presenilin-1 trans-genic mice. Neurobiol Dis 8: 331–342.
  • Evans DA, Hebert LE, Beckett LA, Scherr PA, Albert MS, Chown MJ, Pilgrim DM, Taylor JO (1997). Education and other measures of socioeconomic status and risk of inci-dent Alzheimer disease in a defined population of older persons. Arch Neurol 54: 1399–1405.
  • Fazakerley JK, Allsopp TE (2001). Programmed cell death in virus infections of the nervous system. Curr Top Mi-crobic)] Immunol 253: 95–119.
  • Flescher E, Ledbetter JA, Schieven GL, Vela-Roch N, Fossum D, Dang H, Ogawa N, Talal N (1994). Longitu-dinal exposure of human T lymphocytes to weak oxida-tive stress suppresses transmembrane and nuclear signal transduction. J Immunol 153: 4880–4889.
  • Galasko D, Hansen LA, Katzman R, Wiederholt W, Masliah E, Terry R, Hill LR, Lessin P, Thal LJ (1994). Clinical-neuropathological correlations in Alzheimer's disease and related dementias. Arch Neurol 51: 888–895.
  • Giese A, Kretzschmar HA (2001). Prion-induced neuronal damage-the mechanisms of neuronal destruction in the subacute spongiform encephalopathies. Curr Top Micro-bic)] Immunol 253: 203–217.
  • Grossmann A, Kukull WA, Jinneman JC, Bird TD, Villacres EC, Larson EB, Rabinovitch PS (1993). Intracellular cal-cium response is reduced in CD4+ lymphocytes in Alzheimer's disease and in older persons with Down's syndrome. Neurobiol Aging 14: 177–185.
  • Guo Q, Christakos S, Robinson N, Mattson MP (1998a). Cal-bindin D28k blocks the proapoptotic actions of mutant presenilin 1: reduced oxidative stress and preserved mi-tochondrial function. Proc Natl Acad Sci USA 95: 3227–3232.
  • Guo Q, Fu W, Sopher BL, Miller MW, Ware CB, Martin GM, Mattson MP (1999). Increased vulnerabil-ity of hippocampal neurons to excitotoxic necrosis in presenilin-1 mutant knockin mice. Nat Med 5: 101–107.
  • Guo Q, Furukawa K, Sopher BL, Pham DG, Robinson N, Martin GM, Mattson MP (1996). Alzheimer's PS-1 muta-tion perturbs calcium homeostasis and sensitizes PC12 cells to death induced by amyloid /3-peptide. Neuro-Report 8: 379–383.
  • Guo Q, Robinson N, Mattson MP (1998b). Secreted beta-amyloid precursor protein counteracts the proapoptotic action of mutant presenilin-1 by activation of NF-KB and stabilization of calcium homeostasis. J Biol Chem 273: 12341–12351.
  • Guo Q, Sopher BL, Pham DG, Furukawa K, Robinson N, Martin GM, Mattson MP (1997). Alzheimer's presenilin mutation sensitizes neural cells to apoptosis induced by trophic factor withdrawal and amyloid /3-peptide. J Neurosci 17: 4212–4222.
  • Guse AH (1998). Ca2+ signaling in T-lymphocytes. Grit Rev Immunol 18: 419–448.
  • Handler M, Yang X, Shen J (2000). Presenilin-1 regulates neuronal differentiation during neurogenesis. Develop-ment 127: 2593–2606.
  • Hardy J (1997). Amyloid, the presenilins and Alzheimer's disease. Trends Neurosci 20: 154-159. ibarreta D, Parrilla R, Ayuso MS (1997). Altered Ca2+ home-ostasis in lymphoblasts from patients with late onset Alzheimer disease. Alzheimer Dis Assoc Disord 11: 220-227. ibarreta D, Urcelay E, Parrilla R, Ayuso MS (1998). Dis-tinct pH homeostatic features in lymphoblasts from Alzheimer's disease patients. Ann Neurol 44: 216–222.
  • Janus C, Pearson J, McLaurin J, Mathews PM, Jiang Y, Schmidt SD, Chishti MA, Home P, Heslin D, French J, Mount HT, Nixon RA, Mercken M, Bergeron C, Fraser PE, St George-Hyslop P, Westaway D (2000). A beta pep-tide immunization reduces behavioural impairment and plaques in a model of Alzheimer's disease. Nature 408: 979–982.
  • Karlsson JO, Blennow K, Janson I, Blomgren K, Karlsson I, Regland B, Wallin A, Gottfries CG (1995). Increased proteolytic activity in lymphocytes from patients with early onset Alzheimer's disease. Neurobiol Aging 16: 901–906.
  • Khan AA, Soloski MJ, Sharp AH, Schilling G, Sabatini DM, Li SH, Ross CA, Snyder SH (1996). Lymphocyte apoptosis: mediation by increased type 3 inositol 1,4,5-trispho sphate receptor. Science 273: 503–507.
  • Kim WK, Ko KH (1998). Potentiation of N-methyl-D-aspartate-mediated neurotoxicity by i=unostimulated murine microglia. J Neurosci Res 54: 17–26.
  • Kruman II, Nath A, Mattson MP (1998). HIV-1 protein Tat induces apoptosis of hippocampal neurons by a mechanism involving caspase activation, calcium overload, and oxidative stress. Exp Neurol 154: 276–288.
  • Lanzrein AS, Johnston CM, Perry VH, Jobst KA, King EM, Smith AD (1998). Longitudinal study of inflammatory factors in serum, cerebrospinal fluid, and brain tissue in Alzheimer disease: interleukin-1beta, interleukin-6, interleukin-1 receptor antagonist, tumor necrosis factor-alpha, the soluble tumor necrosis factor receptors I and II, and alpha1-antichymotrypsin. Alzheimer Dis Assoc Disord 12: 215–227.
  • Lee J, Chan SL, Taub DH, Camandola S, Mattson MP (2001). Induction of inflammatory cytokines is potentiated in the brains of presenilin-1 mutant knock-in mice. Soc Neurosci Abstr 27: Program number 860.4.

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