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Research Article

Milk Xanthine Oxidase: Hazard or Benefit?

Pages 231-238 | Published online: 13 Jul 2009

  • Patton S, Keenan TW. The milk fat globule membrane. Biochem Biophys Acta 1975; 415: 273-309.
  • Keenan TW, Patton S. The structure of milk: implications for sampling and storage. A. The milk lipid globule membrane. In: Jensen RG (ed.) Handbook of Milk Composition. New York: Academic Press, 1995: 5-50.
  • Bray RC. Molybdenum iron sulfur flavin hydroxylases and related enzymes. In: Boyer PD (ed.) The Enzymes. New York: Academic Press, 1975: 299-419.
  • Hille R. The mononuclear molybdenum enzymes. Chem Rev 1996; 96: 2757-816.
  • McCord JM. Oxygen-derived free radicals in postischemic tissue injury. N Engl J Med 1985; 12: 159-63.
  • Finkel T. Signal transduction by reactive oxygen species in non-phagocytic cells. J Leukocyte Biol 1999; 65: 337-40.
  • Harrison R. Xanthine oxidoreductase. In: Winyard PG, Blake DR, Evans CH (eds) Free Radicals and Inflammation. Basle: Birkhauser, 2000: 65-81.
  • Hancock JT, Desikan R, Neill SJ. Role of reactive oxygen species in cell signalling pathways. Biochem Soc Trans 2001 ; 29: 345-50.
  • Davies DF. Immunology of human atheroma. In: Freed DLJ (ed.) Health Hazards of Milk. London: Balliere-Tindall, 1984: 201-12.
  • Davies DF, Davies JR, Richards MA. Antibodies to reconstituted dried milk protein in coronary heart disease. J Atheroscler Res 1969; 9: 103-7.
  • Davies DF, Rees BWG, Johnson AP, Elwood PC, Abemethy M. Food antibodies and myocardial infarction. Lancet 1974; i: 1012-14.
  • Toivanen A, Viljanen MK, Svilahti E. IgM and IgG anti-milk antibodies measured by radio-immunoassay in myocardial infarction. Lancet 1975; ii: 205-7.
  • Scott BB, Swinburne ML, McGuffin P, Losowsky MS. Dietary antibodies and myocardial infarction. Lancet 1976; ii: 125-6.
  • Gibney MJ, Gallagher PJ, Sharratt GP, Benning HS, Taylor TG, Pitts JM. Antibodies to heated milk protein in coronary heart disease. Atherosclerosis 1980; 37: 151-5.
  • Davies DF, Rees BWG, Davies PTG. Cows' milk antibodies and coronary heart disease. Lancet 1980; i: 1190-1.
  • Davies DF, Rees BWG, Davies PTG. Bovine milk fat globule and human platelets. Int Lab 1982; 12: 22-4.
  • Harrison R, Benboubetra M, Bryson S, Thomas RD, Elwood PC. Antibodies to xanthine oxidase: elevated levels in patients with acute myocardial infarction. Cardioscience 1990; 1: 183-9.
  • Oster KA. Xanthine oxidase. In: Freed DLJ (ed.) Health Hazards of Milk. London: Balliere-Tindall, 1984: 239-53.
  • Oster KA, Oster JB, Ross DJ. Immune response to bovine xanthine oxidase in atherosclerotic patients. Am Lab 1974; 6: 41-7.
  • Carr CJ, Talbot JM, Fisher KD. A review of the significance of bovine milk xanthine oxidase in the etiology of atherosclerosis. Bethesda, MD: FASEB Life Sciences Research Office; Contract No. FDA 223-75-2020 (Division of Nutrition, Bureau of Foods), 1975.
  • Walker WA, Isselbacher KJ. Uptake and transport of macromolecules by the intestine: possible role in clinical disorder. Gastroenterology 1974; 67: 531-50.
  • Rzucicflo SJ, Zikakis JP. Correlation of dairy food intake with human antibody to bovine milk xanthine oxidase. Proc R Soc Exp Biol Med 1979; 160: 477-82.
  • Paries DA, Granger DN. Xanthine oxidase: biochemistry, distribution and physiology. Acta Physiol Scand Suppl 1986; 548: 87-99.
  • Jarasch E-D, Bruder G, Heid HW. Significance of xanthine oxidase in capillary endothelial cells. Acta Physiol Scand Suppl 1986; 548: 39-46.
  • Yamamoto T, Moriwaki Y, Takahashi S et al. Determination of human plasma xanthine oxidase activity by high-performance liquid chromatography. J Chromatogr B 1996; 681: 395-400.
  • Shamma'a MH, Nasrallah SM, Al-Khalidi UAS. Serum xanthine oxidase. An experience with 2000 patients. Dig Dis 1973; 18: 15-22.
  • Miesel R, Zuber M. Elevated levels of xanthine oxidase in serum of patients with inflammatory and autoimmune rheumatic diseases. Inflammation 1993; 17: 551-61.
  • Tan S, Gelman S, Wheat JK, Parkes DA. Circulating xanthine oxidase in human ischemia-reperfusion. Southern Med J 1995; 88: 479-82.
  • Benboubetra M, Gleeson A, Harris CPD et al. Circulating anti-(xanthine oxidoreductase) antibodies in healthy human adults. Eur J Clin Invest 1997; 27: 611-19.
  • Lewis WHP, Ng YLE Human xanthine oxidase antibody levels: variation in males and females in Chinese and Europeans. Med Lab Sei 1991 ; 48: 84-8.
  • Godsland IF, Wynn V, Crook D, Miller NE. Sex, plasma lipoproteins and atherosclerosis : prevailing assumptions and outstanding questions. Am Heart J 1987; 114: 1467-503.
  • Kannel WB. Metabolic risk factors for coronary heart disease in women: perspective from the Framingham Study. Am Heart J 1987; 114: 413.
  • Gershon H. Is the sequestration of aged erythrocytes mediated by natural autoantibodies ? Israel J Med Sei 1992; 28: 818-26.
  • Clifford AJ, Ho CY, Swenerton H. Homogenized bovine milk xanthine oxidase: a critique of the hypothesis relating to plasmalogen depletion and cardiovascular disease. Am J Clin Nutr 1983; 38: 327-32.
  • Deeth HC. Homogenized milk and atherosclerotic disease: a review. J Dairy Sei 1983; 66: 1419-35.
  • Massey V, Harris CH. Milk xanthine dehydrogenase : the first one hundred years. Biochem Soc Trans 1997; 25: 750-5.
  • Green DE, Pauli R. The antibacterial action of the xanthine oxidase system. Proc Soc Exp Biol Med 1943; 54: 148-50.
  • Lipmann F, Owen CR. The antibacterial effect of enzymatic xanthine oxidation. Science 1943; 98: 246-8.
  • Bjorck L, Claesson O. Xanthine oxidase as a source of hydrogen peroxide for the lactoperoxidase system in milk. J Dairy Sci 1979; 62: 1211-15.
  • Stevens CR, Millar TM, Clinch JG, Kanczler JM, Bodamyali T, Blake DR. Antibacterial properties of xanthine oxidase in human milk. Lancet 2000; 356: 829-30.
  • Godber BLJ, Doel JJ, Sapkota GP et al. Reduction of nitrite to nitric oxide catalyzed by xanthine oxidoreductase. J Biol Chem 2000; 275: 7757-63.
  • Godber BLJ, Doel JJ, Durgan J, Eisenthal R, Harriso n R. A new route to peroxynitrite : a role for xanthine oxidoreductase. FEBS Lett 2000; 475: 93-6.
  • Brunei! i L, Crow JP, Beckman JS. The comparative toxicity of nitric oxide and peroxynitrite to Escherichia coll. Arch Biochem Biophys 1995; 316: 327-34.
  • DeMoss JA, Hsu P-Y. NarK enhances nitrate uptake and nitrite excretion in Escherichia coli. J Bacteriol 1991; 173:3303-10.
  • Cole J. Nitrate reduction to ammonia by enteric bacteria: redundancy, or a strategy for survival during oxygen starvation? FEMS Microbiol Lett 1996; 136: 1-11.
  • Adachi T, Fukushima T, Usami Y, Hirano K. Binding of human xanthine oxidase to sulphated glycosylaminoglycan s on the endothelial cell surface. Biochem J 1993; 289: 523-7.
  • Nakamura M, Yamazaki I. Preparation of bovine milk xanthine oxidase as a dehydrogenase form. J Biochem 1982; 92: 1279-86.
  • Abadeh S, Killacky J, Benboubetra M, Harrison R. Purification and partial characterizatio n of xanthine oxidase from human milk. Biochim Biophys Acta 1992; 1117: 25-32.
  • Godber B, Sanders SA, Harrison R, Eisenthal R, Bray RC. > 95% of xanthine oxidase in human milk is present as the demolybdo form, lacking molybdopterin. Biochem Soc Trans 1997; 25: 519S.
  • Bray RC, Lowe D, Godber B, Harrison R, Eisenthal R. Properties of xanthine oxidase from human milk: the enzyme is grossly deficient in molybdenum and substantially deficient in iron-sulphur centres. In: Ghisla S, Cronack P, Macheroux P, Sund H (eds) Flavins and Flavoproteins. Berlin: Agency for Scientific Publications Rudolf Weber, 1999: 775-8.
  • Harrison R. Human xanthine oxidoreductase: in search of a function. Biochem Soc Trans 1997; 25: 786-91.
  • Brown A-M, Benboubetra M, Ellison M, Powell D, Reckless JD, Harrison R. Molecular activation-deactivation of xanthine oxidase in human milk. Biochim Biophys Acta 1995; 1245: 248-54.
  • Salisbury V, Pfoest A, Wiesinger-Mayer H, Lewis R, Bowker KE, MacGowan AP. Use of a clinical Escherichia cou isolate expressing lux genes to study the antimicrobial pharmacodynamics of moxiflaxacin. J Antimicrob Chemother 1999; 43: 829-32.
  • Van den Munckhof RJM, Vreeling-Sindelarova HA, Schellens JPM, Van Noorden CJF, Frederiks WM. Ultrastructural localization of xanthine oxidase activity in the digestive tract of the rat. Histochem J 1995; 27: 897-905.
  • Kovar MG, Serdula MK, Marks JS, Fraser DW. Review of the epidemiologic evidence for an association between infant feeding and infant health. Pediatrics Suppl. 1984; 74: 615-38.
  • Beaudry M, Dufour R, Marcoux S. Relation between infant feeding and infections during the first six months of life. J Pediatr 1995; 126: 191-7.
  • Georgieff M, Piovanetti Y, Queenan J. Breast feeding and the use of human milk. Work group on breast feeding, American Academy of Pediatrics. Pediatrics 1997; 100: 1035-8.

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