References
- White JW Jr. Composition of honey. In: Carne E (ed.) Honey. A Comprehensive Survey. London: Heinemann, 1979, 157–207.
- White JW Jr. Honey. Adv Food Res 1978; 24: 287–375.
- Lau J. Bees and Honey, 1st edn. Melbourne: Lothian Publishing Company, 1976, 41–9.
- Salem SN. Honey regimen in gastrointestinal disorders. Proceedings of the First International Conference on Islamic Medicine, Kuwait. Bull Islam Med 1981; 1: 358–62.
- Haffejee IE, Moosa A. Honey in the treatment of infantile gastroenteritis. Br Med J 1985; 290: 1886–7.
- Bergman A, Yanai J, Weiss J, Bell D, David MP. Acceleration of wound healing by topical application of honey: an animal model. Am J Surg 1983; 145: 374–6.
- Efem SEE. Clinical observation on the wound healing properties of honey. Br J Surg 1988; 75: 679–81.
- Subrahmanyam M. Topical application of honey in the treatment of burns. Br J Surg 1991; 76: 497–8.
- Postmes TJ, Bosch MMC, Dutrieux R, Van Baare J, Hoekstra MJ. Speeding up the healing of burns with honey. In: Mizrahi, Lensky (eds) Bee Products. New York: Plenum Press, 1996, 57–65.
- Allen KL, Molan PC, Reid GM. A survey of the antibacterial activity of some New Zealand honeys. J Pharm Pharmacol 1991; 43: 817–22.
- Ali ATMM, Chowdhury MNH, Al-Humayyd MS. Inhibitory effect of natural honey onHelicobacter pylori. Trop Gastroenterol 1991; 12: 139–43.
- Efem SEE, Udoh KT, Iwara CI. The antimicrobial spectrum of honey and its clinical significance.Infection 1992; 20: 227–9.
- Somal N, Coely KE, Molan PC, Hancock BM. Susceptibility of Helicobacter pylori to the antibacterial activity of manuka honey. J R Soc Med 1994; 87: 9–12.
- Ali ATMM, Al-Humayyd MS, Madan BR. Natural honey prevents indomethacin- and ethanol- induced gastric lesions in rats. Saudi Med J 1990; 11: 275–9.
- Ali ATMM. Prevention of ethanol-induced gastric lesions in rats by natural honey, and its possible mechanism of action. Scand J Gastroenterol 1991; 26: 281–8.
- Ali ATMM. Natural honey exerts its protective effects against ethanol-induced gastric lesions in rats by preventing depletion of glandular nonprotein sulfhydryls. Trop Gastroenterol 1995; 16: 18–25.
- Ali ATMM. Natural honey accelerates healing of indomethacin-induced antral ulcers in rats. Saudi Med J 1995; 16: 161–6.
- Ali ATMM, Al-Swayeh OA. The role of nitric oxide in gastric protection by honey. Saudi Med J 1996; 17: 301–6.
- Ali ATMM, Al-Swayeh OA. Natural honey prevents ethanol-induced increased vascular permeability changes in the rat stomach. J Ethnopharmacol 1997; 55: 231–8.
- Ali ATMM, Al-Swayeh OA, Al-Humayyd MS, Mustafa AA, Al-Rashed RS, Al-Tuwaijiri AS. Natural honey prevents ischaemia-reperfusion induced gastric mucosal lesions and increased vascular permeability in rats. Eur J Gastroenterol Hepatol 1997; 9: 1101–7.
- Swayeh OA, Ali ATMM. Effect of ablation of capsaicin sensitive neurons on gastric protection by honey and sucralfate. Hepato-Gastroenterology 1998; 45: 297–302.
- Gharzouli K, Gharzouli A, Amira S, Khennouf S. Prevention of ethanol-induced gastric lesions in rats by natural honey and glucose–fructose–sucrose–maltose mixture. Pharmacol Res 1999; 39: 151–6.
- Ali ATMM, Al-Humayyd MS, Al-Swayeh OA. Does a glucose–fructose–sucrose–maltose mixture (as present in honey) really possess gastric protection effects? Pharm Res 2001; 43: 111–12.
- Mahgoub AA, El-Medany AH, Hagar HH, Sabaht DM. Protective effect of natural honey against acetic acid-induced colitis in rats. Trop Gastroent 2002; 23: 82–7.
- Aase S. Disturbances in the balance between aggressive and protective factors in the gastric and duodenal mucosa. Scand J Gastroenterol 1989; 24 (suppl 163): 17–23.
- Marshall BJ, Warren JR. Unidentified curved bacilli in the stomach of patients with gastritis and peptic ulceration. Lancet 1984; i: 1311–14.
- Colgan JG, Gilligan D, Humphries H. Campylobacter pylori and recurrence of duodenal ulcers: a 12 month follow up study. Lancet 1987; ii: 1109–11.
- Labenz J, Borsch G. Evidence for the essential role of Helicobacter pylori in gastric ulcer disease.Gut 1994; 35: 19–22.
- Marshall BJ. Helicobacter pylori. Am J Gastroenterol 1994; 89: S116–28.
- Marshall BJ, Kangton SR. Urea hydrolysis in patients with Campylobacter pyloridis infection.Lancet 1986; i: 965–6.
- Kawano S, Tsujii M, Fusamoto H, Sato N, Kamada T. Chronic effect of intragastric ammonia on gastric mucosal structures in rats. Dig Dis Sci 1991; 36: 33–8.
- Tsujii M, Kawano S, Tsuji S, Fusamoto H, Kamada T, Sato N. Mechanism of gastric mucosal damage induced by ammonia. Gastroenterology 1992; 102: 1881–8.
- Murakami M, Saita H, Teramura S et al. Gastric ammonia has a potent ulcerogenic action on the rat stomach. Gastroenterology 1993; 105: 1710–15.
- Mori S, Kaneko H, Mitsuma T, Hayakawa T, Yamaguchi C, Uruma M. Implications of gastric topical bioactive peptides in ammonia-induced acute gastric mucosal lesions in rats. Scand J Gastroenterol 1998; 33: 386–93.
- Takaishi O, Arakawa T, Yamasaki K et al. Protective effect of rebamipide against ammonia- induced gastric mucosal lesions. Dig Dis Sci 1998; 43 (suppl 9): S78–82.
- Kosower NS, Kosower EM. The glutathione status of the cells. Int Rev Cytol 1978; 54: 109–60.
- Szabo S, Trier JS, Frankel PW. Sulfhydryl compounds may mediate gastric cytoprotection. Science 1981; 214: 200–2.
- Loguercio C, Taranto D, Beneduce F et al. Glutathione prevents ethanol-induced gastric mucosal damage and depletion of sulfhydryl compounds in humans. Gut 1993; 34: 161–5.
- Szabo S, Brown A. Prevention of ethanol-induced vascular injury and gastric mucosal lesions by sucralfate and its components: possible role of endogenous sulfhydryls. Proc Soc Exp Bio Med 1987; 185: 493–7.
- Ali ATMM. The role of nitric oxide and sulphydryls in gastric mucosal protection induced by sodium cromoglycate in rats. J Pharm Pharmacol 1995; 47: 739–43.
- Ali ATMM. The role of nonprotein sulphydryls in the protective effects of antioxidants against ethanol-induced vascular permeability changes in the rat stomach. Inflammopharmacology 1998; 6: 41–51.
- Al-Swayeh OA, Al-Humayyd MS, Mustafa AA, Al-Tuwaijiri RS, Al-Rashed RS, Ali ATMM. Sucralfate attenuates gastric mucosal lesions and increased vascular permeability induced by ischaemia and reperfusion in rats. J Gastroent Hepatol 1997; 12: 481–9.
- Jankowski J, Bridges AB, Scott N, Wormsley KG, Belch JJF. Circulating free-radical markers and peptic ulcer disease. Eur J Gastroenterol Hepatol 1991; 3: 823–8.
- Murakami M, Yoo JK, Saita H, Seiki M, Inada M, Miyake T. Effects of 16,16-dimethyl- prostaglandin E2 on ammonia- and ethanol-induced mucosal lesions in the rat. J Clin Gastroenterol 1988; 10 (suppl 1): S65–71.
- Kato S, Nishiwaki H, Konaka A, Takeuchi K. Mucosal ulcerogenic action of monochloramine in rat stomachs. Effects of polaprezinc and sucralfate. Dig Dis Sci 1997; 42: 2156–63.
- Ali ATMM, Al-Swayeh OA. Probable role of nonprotein sulfhydryls (NP-SH) in the protective mechanism of natural honey against ammonia-induced gastric lesions in rats. Proceedings of the International Symposium on Complementary and Alternative Medicine, Saudi Arabia, 1–3 May 2001.
- Sedlak J, Lindsay RH. Estimation of total, protein-bound, and nonprotein sulfhydryl groups in tissue with Ellman’s reagent. Anal Biochem 1968; 25: 192–205.
- Babson JR, Abell NS, Reed DJ. Protective role of the glutathione redox cycle against adriamycin- mediated toxicity in isolated hepatocytes. Biochem Pharmacol 1981; 30: 2299–304.
- Olson CE. Glutathione modulates toxic oxygen metabolite injury of canine chief cell monolayers in primary culture. Am J Physiol 1988; 254: G49–56.
- Romano A, Razandi M, Raza A, Szabo S, Ivey J. Cysteamine protects gastric epithelial cell monolayers against drug induced damage: evidence for cellular protection by sulphydryl compound. Gut 1992; 33: 30–8.
- Karmelli F, Okon E, Rachmilewitz D. Sulphydryl blocker induced gastric damage is ameliorated by scavenging of free radicals. Gut 1996; 38: 826–31.
- Frankel S, Robinson GE, Berenbaum MR. Antioxidant capacity and correlated characteristics of 14 unifloral honeys. J Apicul Res 1998; 37: 27–31.
- Molan P. Why honey is effective as a medicine. 2. The scientific explanation of its effects. Bee World 2001; 82: 22–4.