966
Views
4
CrossRef citations to date
0
Altmetric
Original Article

Effects of heart rate reduction with ivabradine on the international ındex of erectile function (IIEF-5) in patients with heart failure

ORCID Icon, , , &
Pages 93-98 | Received 11 Jul 2017, Accepted 17 Aug 2017, Published online: 26 Aug 2017

References

  • Hatzimouratidis K, Amar E, Eardley I, et al. Guidelines on male sexual dysfunction: erectile dysfunction and premature ejaculation. Eur Urol. 2010;57:804–814.
  • Vlachopoulos C, Ioakeimidis N, Terentes-Printzios D, et al. The triad: erectile dysfunction–endothelial dysfunction–cardiovascular disease. CPD. 2008;14:3700–3714.
  • Schwarz ER, Rastogi S, Kapur V, et al. Erectile dysfunction in heart failure patients. J Am Coll Cardiol. 2006;1948:1111–1119.
  • Baraghoush A, Phan A, Willix RD Jr, et al. Erectile dysfunction as a complication of heart failure. Curr Heart Fail Rep. 2010;7:194–201.
  • Baumhakel M, Bohm M. Erectile dysfunction correlates with left ventricular function and precedes cardiovascular events in cardiovascular high-risk patients. Int J Clin Pract. 2007;61:361–366.
  • Swedberg K, Komajda M, Böhm M, et al. Ivabradine and outcomes in chronic heart failure (SHIFT): a randomised placebo-controlled study. Lancet. 2010;376:875-885.
  • Custodis F, Baumhäkel M, Schlimmer N, et al. Heart rate reduction by ivabradine reduces oxidative stress, improves endothelial function, and prevents atherosclerosis in apolipoprotein E-deficient mice. Circulation. 2008;117:2377–2387.
  • Turunç T, Deveci S, Güvel S, et al. The assessment of Turkısh valıdatıon wıth 5 questıon versıon of international index of erectile functıon (IIEF-5). Türk Üroloji Dergisi. 2007;33:45–49.
  • Rastogi S, Rodriguez JJ, Kapur V, et al. Why do patients with heart failure suffer from erectile dysfunction? A critical review and suggestions on how to approach this problem. Int J Impot Res. 2005;17 Suppl 1:S25–S36.
  • Lue TF. Erectile dysfunction. N Engl J Med. 2000;342:1802–1813.
  • Vlachopoulos C, Jackson G, Stefanadis C, et al. Erectile dysfunction in the cardiovascular patient. Eur Heart J. 2013;34:2034–2046.
  • Baumhakel M, Custodis F, Schlimmer N, et al. Heart rate reduction with ivabradine improves erectile dysfunction in parallel to decrease in atherosclerotic plaque load in ApoE-knockout mice. Atherosclerosis. 2010;212:55–62.
  • Bohm M, Baumhakel M, Teo K, et al. Erectile dysfunction predicts cardiovascular events in high-risk patients receiving telmisartan, ramipril, or both: The ONgoing Telmisartan Alone and in combination with Ramipril Global Endpoint Trial/Telmisartan Randomized AssessmeNt Study in ACE iNtolerant subjects with cardiovascular Disease (ONTARGET/TRANSCEND) Trials. Circulation. 2010;121:1439–1446.
  • Kratz MT, Schumacher H, Sliwa K, et al. Heart rate and blood pressure interactions in the development of erectile dysfunction in high-risk cardiovascular patients. Eur J Prev Cardiolog. 2014;21:272–280.
  • Drouin A, Gendron ME, Thorin E, et al. Chronic heart rate reduction by ivabradine prevents endothelial dysfunction in dyslipidaemic mice. Br J Pharmacol. 2008;154:749–757.
  • Zugck C, Martinka P, Stockl G. Ivabradine treatment in a chronic heart failure patient cohort: symptom reduction and improvement in quality of life in clinical practice. Adv Ther. 201431:961–974.
  • Manolis A, Doumas M. Antihypertensive treatment and sexual dysfunction. Curr Hypertens Rep. 2012;14:285–292.
  • Baumhäkel M, Schlimmer N, Büyükafşar K, et al. Nebivolol, but not metoprolol, improves endothelial function of the corpus cavernosum in apolipoprotein E-knockout mice [10.1124/jpet.107.135681]. J Pharm Exp Ther. 2008;325:818.
  • Solomon H, Samarasinghe YP, Feher MD, et al. Erectile dysfunction and statin treatment in high cardiovascular risk patients. Int J Clin Pract. 2006;60:141–145.
  • Jaarsma T, Dracup K, Walden J, et al. Sexual function in patients with advanced heart failure. Heart Lung. 1996;25:262–270.
  • Apostolo A, Vignati C, Brusoni D, et al. Erectile dysfunction in heart failure: correlation with severity, exercise performance, comorbidities, and heart failure treatment. J Sex Med. 2009;6:2795–2805.
  • Ades PA, Keteyian SJ, Balady GJ, et al. Cardiac rehabilitation exercise and self care for chronic heart failure. JACC Heart Failure. 2013;241:540–547.

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.