References
- Smith CE. Epidemiology of acute coccidioidomycosis with erythema nodosum. Am J Pub Health 1940; 30: 600–611.
- Dooley DP, Cox RA, Hestilow KL, Dolan MJ, Magee DM. Cytokine induction in human coccidioidomycosis. Infect Immun 1994; 62: 3980–3983.
- Einstein H, Catanzaro C. Coccidioidomycosis. In. Washington, D.C.: National Foundation for Infectious Disease; 1996: 1–426.
- Woo JH, Lee JS, Lee DW. A case of disseminated coccidioido-mycosis - autopsy report. J Korean Med Sci 1996; 11: 258–264.
- Dosanjh A, Theodore J, Pappagianis D. Probable false positive coccidioidal serologic results in patients with cystic fibrosis. Pediatr Transplant 1998; 2: 313–317.
- Logan JL, Blair JE, Galgiani JN. Coccidioidomycosis compli-cating solid organ transplantation. Semin Respir Infect 2001; 16: 251–256.
- Wright PW, Pappagianis D, Wilson M. Donor-related coccidioi-domycosis in organ transplant recipients. Clin Infect Dis 2003; 37: 1265–1269.
- Blair JE, Douglas DD, Mulligan DC. Early results of targeted prophylaxis for coccidioidomycosis in patients undergoing orthotopic liver transplantation within an endemic area. Transpl Infect Dis 2003; 5: 3–8.
- Walker MP, Brody CZ, Resnik R. Reactivation of coccidioido-mycosis in pregnancy. Obstet Gynecol 1992; 79: 815–817.
- Peterson CM, Schuppert K, Kelly PC, Pappagianis D. Cocci-dioidomycosis and pregnancy. Obstet Gynecol Surv 1993; 48: 149–156.
- Williams FM, Markides V, Edgeworth J, Williams AI Reactiva-tion of coccidioidomycosis in a fit American visitor. Thorax 1998; 53: 811–812.
- Pappagianis D. Clinical presentation of infectious entities. In: Einstein H (ed.). Coccidioidomycosis. Washington, D.C.: Na-tional Foundation for Infectious Disease, 1996: 9–11.
- Minamoto G, Armstrong D. Fungal infections in AIDS. Histoplasmosis and coccidioidomycosis. Infect Dis Clin North Am 1988; 2: 447–456.
- Bharucha NE, Ramamoorthy K, Sorabjee J, Kuruvilla T. All that caseates is not tuberculosis. Lancet 1996; 348: 1313.
- Galgiani JN Coccidioidomycosis: a regional disease of national importance. Rethinking approaches for control. Ann Intern Med 1999; 130: 293–300.
- Catanzaro A, Galgiani JN, Levine BE. Fluconazole in the treatment of chronic pulmonary and nonmeningeal disseminated coccidioidomycosis. NIAID Mycoses Study Group. Am J Med 1995; 98: 249–256.
- Sugar AM. Treatment of fungal infections in patients infected with the human immunodeficiency virus. Pharmacotherapy 1990; 10: 154S–158S.
- Kauffman CA. Endemic mycoses in patients with hematologic malignancies. Semin Respir Infect 2002; 17: 106–112.
- Caldwell JW, Welch G, Johnson RH, Einstein H. The economic impact of coccidioidomycosis in Kern County, California, 1991–1993. In: Einstein H, Catanzaro C (eds). Coccidioidomycosis. Washington, D.C.: National Foundation for Infectious Disease, 1996: 88–97.
- Barnato AE, Sanders GD, Owens DK. Cost-effectiveness of a potential vaccine for Coccidioides immitis. Emerg Infect Dis 2001; 7: 797–806.
- Cole GT, Kirkland TN. Conidia of Coccidioides immitis: their significance in disease initiation. In: Cole GT, Hoch HC (eds). The Fungal Spore and Disease Initiation in Plants and Animals. New York, NY: Plenum Press, 1991: 403–443.
- Burt A, Carter DA, Koenig GL, White TJ, Taylor JW. Molecular markers reveal cryptic sex in the human pathogen Coccidioides immitis. Proc Natl Acad Sci USA 1996; 93: 770–773.
- Pappagianis D. Epidemiology of coccidioidomycosis. Curr Top Med Mycol 1988; 2: 199–238.
- Negroni R. State of the art in the treatment of endemic systemic mycoses. Revista lberoamericana de Micologia 1996; 13: S44–S50.
- George LK, Ajello L, Gordon MA. A selective medium for the isolation of Coccidioides immitis. Science 1951; 114: 387–398.
- Egeberg RO, Elsonin A, Egeberg MC. Effect of salinity and temperature on Coccidioides immitis and three antagonistic soil saprophytes. J Bacteriol 1964; 88: 473–476.
- Greene DR, Koenig G, Fisher MC, Taylor JW. Soil isolation and molecular identification of Coccidioides immitis. Mycologia 2000; 92: 406–410.
- Saubolle MA. Life cycle and epidemiology of Coccidioides immitis. In: Einstein H, Catanzaro C (eds). Coccidioidomycosis. Washington, D.C.: National Foundation for Infectious Disease, 1996: 1–8.
- Walvoord MA, Phillips FM, Stonestrom DA. A reservoir of nitrate beneath desert soils. Science 2003; 302: 1021–1024.
- Eulalio KD, de Macedo RL, Cavalcanti MA. Coccidioides immitis isolated from armadillos (Dasypus novemcinctus) in the state of Piaui, northeast Brazil. Mycopathologia 2001; 149: 57–61.
- Johnson LR, Herrgesell EJ, Davidson AP, Pappagianis D. Clinical, clinicopathologic, and radiographic findings in dogs with coccidioidomycosis: 24 cases (1995-2000). J Am Vet Med Assoc 2003; 222: 461–466.
- Rubensohn M, Stack S. Coccidiomycosis in a dog. Canadian Vet Journal 2003; 44: 159–160.
- Harrison WR, Merbs CF, Leathers CR. Evidence of coccidioi-domycosis in the skeleton of an ancient Arizona Indian. J Infect Dis 1991; 164: 436–437.
- Fowler ME, Pappagianis D, Ingram I. Coccidioidomycosis in llamas in the United States: 19 cases (1981-1989). J Am Vet Med Assoc 1992; 201: 1609–1614.
- Timm KI, Sonn RJ, Hultgren BD. Coccidioidomycosis in a Sonoran Gopher snake Pituophismelanoleusus affinis. J Med & Vet Mycol 1988; 26: 101–104.
- Casadevall A, Pirofski L-A. Microbial virulence results from the interaction between host and microorganism. Trends Microbiol 2003; 11: 157–158.
- Fisher MC, Koenig G, White TJ, Taylor JW. A test for concordance between the multilocus genealogies of genes and microsatellites in the pathogenic fungus Coccidioides immitis. Mol Biol Evol 2000; 17: 1164–1174.
- Burt A, Dechairo BM, Koenig GL. Molecular markers reveal differentiation among isolates of Coccidioides immitis from California, Arizona and Texas. Mol Ecol 1997; 6: 781–786.
- Koufopanou V, Burt A, Taylor JW. Concordance of gene genealogies reveals reproductive isolation in the pathogenic fungus Coccidioides immitis. Proc Natl Acad Sci USA 1997; 94: 5478–5482.
- Koufopanou V, Burt A, Szaro T, Taylor JW. Gene genealogies, cryptic species, and molecular evolution in the human pathogen Coccidioides immitis and relatives (Ascomycota, Onygenales).
- Fisher MC, Koenig GL, White TJ. Biogeographic range expan-sion into South America by Coccidioides immitis mirrors New
- Currah RS. Taxonomy of the Onygenales: Arthrodermataceae, Gymnoascaceae, Myxotrichaceae and Onygenaceae. Mycotaxon 1985; 24: 1–216.
- Pan S, Sigler L, Cole GT. Evidence for a phylogenetic connection between Coccidioides immitis and Uncinocarpus reesii (Onygenaceae). Microbiology 1994; 140: 1481–1494.
- Padhye AA, Smith G, Standard PG, McLaughlin D, Kaufman L. Comparative evaluation of chemiluminescent DNA probe assays and exoantigen tests for rapid identification of Blastomyces dermatitidis and Coccidioides immitis. J Clin Microbiol 1994; 32: 867–870.
- Hayden RT, Qian X, Roberts GD, Lloyd RV. In situ hybridization for the identification of yeastlike organisms in tissue section. Diag Mol Pathol 2001; 10: 15–23.
- Pan S, Cole GT. Molecular and biochemical characterization of a Coccidioides immitis -specific antigen. Infect Immun 1995; 63: 3994–4002.
- Sandhu GS, Kline BC, Stockman L, Roberts GD. Molecular probes for diagnosis of fungal infections. J Clin Microbiol 1995; 33: 2913–2919.
- Muller FM, Groll AH, Walsh TJ. Current approaches to diagnosis and treatment of fungal infections in children infected with human immuno deficiency virus. Eur J Pediatr 1999; 158: 187–199.
- Weiden MA, Saubolle MA. The histopathology of coccidioido-coccidioidomycosis. In: Einstein HE, Catanzaro C (eds). Coccidioidomycosis. Washington D.C.: National Foundation for Infectious Disease, 1996: 12–17.
- Hagman HM, Madnick EG, D'Agostino AN. Hyphal forms in the central nervous system of patients with coccidioidomycosis.
- Levine HB. Purification of the spherule - endospore phase of Coccidioides immitis. Sabouraudia 1961; 1: 112–115.
- Polesky A, Kirsch CM, Snyder LS. Airway coccidioidomycosis-Polesky A, Kirsch CM, Snyder LS. Airway coccidioidomycosisreport of cases and review. Clin Infect Dis 1999; 28: 1273–1280.
- Nicas M, Hubbard A. A risk analysis for airborne pathogens with low infectious doses: application to respirator selection against Coccidioides immitis spores. Risk Anal 2002; 22: 1153–1163
- Shubitz L, Peng T, Perrill R. Protection of mice against Coccidioides immitis intranasal infection by vaccination with recombinant antigen 2/PRA. Infect Immun 2002; 70: 3287–3289.
- Linsangan LC, Ross LA. Coccidioides immitis infection of the neonate: two routes of infection. Ped Infect Dis J 1999; 18: 171–173.
- Fisher MC, Koenig GL, White TJ, Taylor JW. Pathogenic clones versus environmentally driven population increase: analysis of an epidemic of the human fungal pathogen Coccidioides immitis. J Clin Microbiol 2000; 38: 807–813.
- Kolivras KN, Comrie AC. Modeling valley fever (coccidioidomycosis) incidence on the basis of climate conditions. Int J Biometeorol 2003; 47: 87–101.
- Coccidioidomycosis in travelers returning from Mexico - Pennsylvania, 2000. MMWR 2000; 49: 1004–1006.
- Jones JL, Fleming PL, Ciesielski CA. Coccidioidomycosis among persons with AIDS in the United States. J Infect Dis 1995; 171: 961–966.
- Ampel NM. Delayed-type hypersensitivity, in vitro T-cell responsiveness and risk of active coccidioidomycosis among HIVinfected patients living in the coccidioidal endemic area. Med Mycol 1999; 37: 245–250.
- Rosenstein NE, Emery KW, Werner SB. Risk factors for severe pulmonary and disseminated coccidioidomycosis: Kern County, California, 1995–/1996. Clin Infect Dis 2001; 32: 708–715.
- Virgili A, Zampino MR, Mantovani L. Fungal skin infections in organ transplant recipients. Am J Clin Dermatol 2002; 3: 19–35.
- Tripathy U, Yung GL, Kriett JM. Donor transfer of pulmonary coccidioidomycosis in lung transplantation. Ann Thoracic Surgery 2002; 73: 306–308.
- Gabriel AP, Martinez-Ordaz VA, Velasco-Rodreguez VM, Lazo- Saenz JG, Cicero R. Prevalence of skin reactivity to coccidioidin and associated risks factors in subjects in a Northern city of Mexico. Arch Med Res 1999; 30: 388–392.
- Cairns L, Blythe D, Kao A. Outbreak of coccidioidomycosis in Washington state residents returning from Mexico. Clin Infect Dis 2000; 30: 61–64.
- Anonymous. Coccidioidomycosis among persons attending the world championship of model airplane flying-Kern County, California, October 2001. MMWR 2001; 50: 1106–1107.
- Anonymous. Coccidioidomycosis in workers at an archeologic site-Dinosaur National Monument, Utah, June–/July 2001. MMWR 2001; 50: 1005–1008.
- Chaturvedi V, Ramani R, Gromadzki S. Coccidioidomycosis in New York State. Emerg Infect Dis 2000; 6: 25–29.
- Ogiso A, Ito M, Koyama M. Pulmonary coccidioidomycosis in Japan: case report and review. Clin Infect Dis 1997; 25: 1260–1261.
- Zalatnai A, Zala J, Sandor G. Coccidioidomycosis in Hungary. The first import case. POR 1998; 4: 147–151.
- Jang J, Lee HJ, Lee I. The first imported case of pulmonary coccidioidomycosis in Korea. J Korean Med Sci 1999; 14: 206–209.
- Anonymous. Coccidioidomycosis –/ Arizona, 1990–/1995. MMWR 1996; 45: 1069–1073.
- Anonymous. Increase in coccidioidomycosis –/ Arizona, 1998–/ 2001. MMWR 2003; 52: 109–112.
- Ampel NM, Mosley DG, England B. Coccidioidomycosis in Arizona: increase in incidence from 1990 to 1995. Clin Infect Dis 1998; 27: 1528–1530.
- Smith C, Whiting E, Baker E. The use of coccidioidin. Am Rev Tuber 1948; 57: 330–360.
- Smith C, Saito M, Simmons S. Patterns of 39,500 serologic tests in coccidioidomycosis. JAMA 1956; 160: 546–552.
- Kirkland TN, Fierer J. Coccidioidomycosis: a reemerging infectious disease. Emerg Infect Dis 1996; 2: 192–199.
- Crum NF, Lederman ER, Hale BR, Lim ML, Wallace MR. A cluster of disseminated coccidioidomycosis cases at a US military hospital. Mil Med 2003; 168: 460–464.
- Hooper R, Poppell G, Curley R, Husted S, Schillaci R. Coccidioidomycosis among military personnel in Southern California. Mil Med 1980; 145: 620–623.
- Crum N, Lamb C, Utz G, Amundson D, Wallace M. Coccidioi-domycosis outbreak among United States Navy SEALs training in a Coccidioides immitis-endemic area-Coalinga, California. J Infect Dis 2002; 186: 865–868.
- Dixon DM. Coccidioides immitis as a Select Agent of bioterror-ism. J Appl Microbiol 2001; 91: 602–605.
- Fierer J, Kirkland T. Questioning CDC's "select agent" criteria. Science 2002; 295: 43.
- Stevens DA. Coccidioidomycosis: a text. New York, NY: Plenum Medical, 1980.
- Pappagianis D, Levin H, Smith C, Berman R, Kobayashi G. Immunization of mice with viable C. immitis. J Immunol 1961; 86: 28–34.
- Converse J. The effect of nonviable and viable vaccines in experimental coccidioidomycosis. Am Rev Resp Dis 1965; 92: 159–174.
- Sorensen KN, Clemons KY, Stevens DA. Murine models of blastomycosis, coccidioidomycosis, and histoplasmosis. Myco-pathologia 1999; 146: 53–65.
- Kirkland TN, Fierer J. Inbred mouse strains differ in resistance to lethal Coccidioides immitis infection. Infect Immun 1983; 40: 912–916.
- Harboe M, Andersen P, Colston MJ. European Commission COST/STD Initiative. Report of the expert panel IX. Vaccines against tuberculosis. Vaccine 1996; 14: 701–716.
- Rappuoli R, Del Giudice G. Identification of vaccine targets. In: Paoletti L, McInnes P (eds). Vaccine: From Concept to Clinic. Boca Raton: CRC Press, 1999: 1–17.
- Mendez S, Tabbara K, Belkaid Y. Coinjection with CpG-containing immunostimulatory oligodeoxynucleotides reduces the pathogenicity of a live vaccine against cutaneous Leishma-niasis but maintains its potency and durability. Infect Immun 2003; 71: 5121–5129.
- Okeke C, Cole GT. Morphological defects and loss of virulence of Coccidioides posadasii caused by disruption of CHS5, encoding a chitin synthase with a myosin motor-like domain. In: 103rd General Meeting of the American Society for Micro-biology, Washington, D.C., May 18–22, 2003; F23 p. 227.
- Levine HB, Cobb J, Smith C. Immunity to coccidioidomycosis induced in mice by purified spherule, arthrospore, and mycelial vaccines. Trans N Y Acad Sci 1960; 22: 436–449.
- Pappagianis D. Evaluation of the protective efficacy of the killed Coccidioides immitis spherule vaccine in humans. The Valley Fever Vaccine Study Group. Am Rev Resp Dis 1993; 148: 656–660.
- Cox RA, Magee DM. Protective immunity in coccidioidomy-cosis. Res Immunol 1998; 149: 417–428.
- Mosmann TR, Coffman RL. Heterogeneity of cytokine secretion patterns and functions of helper T cells. Adv Immunol 1989; 46: 111–147.
- Hatton RD, Weaver CT. T-bet or not T-bet. Science 2003; 302: 993–994.
- Magee DM, Cox RA. Interleukin-12 regulation of host defenses against Coccidioides immitis. Infect Immun 1996; 64: 3609–3613.
- Cox RA, Magee DM. Production of tumor necrosis factor alpha, interleukin-1 alpha, and interleukin-6 during murine coccidioi-domycosis. Infect Immun 1995; 63: 4178–4180.
- Magee DM, Cox RA. Roles of gamma interferon and inter-leukin-4 in genetically determined resistance to Coccidioides immitis. Infect Immun 1995; 63: 3514–3519.
- Munder M, Eichmann K, Moran JM. Th1/Th2-regulated expression of arginase isoforms in murine macrophages and dendritic cells. J Immunol 1999; 163: 3771–3777.
- Kirkland TN, Cole GT. Coccidioidomycosis: pathogenesis, immune response and vaccine development. In: Calderone RA, Cihlar LC (eds). Fungal Pathogenesis: Principles and Applica-tions. New York: Marcel Dekker, 2002: 365–399.
- Huffnagle GB, Deepe GS. Innate and adaptive determinants of host susceptibility to medically important fungi. Curr Opin Microbiol 2003; 6: 344–350.
- Drutz DJ, Huppert M. Coccidioidomycosis: factors affecting the host-parasite interaction. J Infect Dis 1983; 147: 372–390.
- Paananen A, Vuorimaa E, Torkkeli M. Structural hierarchy in molecular films of two class II hydrophobins. Biochemistry 2003; 42: 5253–5258.
- Paris S, Debeaupuis JP, Crameri R. Conidial hydrophobins of Aspergillus fumigatus. Appl Environ Microbiol 2003; 69: 1581–1588.
- Zhang F, Liang Z, Matsuki N. A murine locus on chromosome 18 controls NKT cell homeostasis and Th cell differentiation. J Immunol 2003; 171: 4613–4620.
- Abuodeh RO, Shubitz LF, Siegel E. Resistance to Coccidioides immitis in mice after immunization with recombinant protein or a DNA vaccine of a proline-rich antigen. Infect Immun 1999; 67: 2935–2940.
- Liu T, Matsuguchi T, Tsuboi N, Yajima T, Yoshikai Y Differences in expression of toll-like receptors and their reactiv-ities in dendritic cells in BALB/c and C57BL/6 mice. Infect Immun 2002; 70: 6638–6645.
- Richards JO, Ampel NM, Galgiani JN, Lake DF. Dendritic cells pulsed with Coccidioides immitis lysate induce antigen-specific naive T cell activation. J Infect Dis 2001; 184: 1220–1224.
- Bourke E, Bosisio D, Golay J, Polentarutti N, Mantovani A. The toll-like receptor repertoire of human B lymphocytes: inducible and selective expression of TLR9 and TLR10 in normal and transformed cells. Blood 2003; 102: 956–963.
- Traynor TR, Huffnagle GB. Role of chemokines in fungal infections. Med Mycol 2001; 39: 41–50.
- Roeder A, Kirschning CJ, Rupec R, Schaller M, Korting HC. Toll-like receptors and innate antifungal responses. Trends Microbiol 2004; 12: 44–49.
- Chandler FW, Kaplan W, Ajello L. Color Atlas and Text of the Histopathology of Mycotic Diseases. London: Library of Con-gress, 1980: 182–189.
- Shi Y, Evans JE, Rock KL. Molecular identification of a danger signal that alerts the immune system to dying cells. Nature 2003; 425: 516–521.
- Heath WR, Carbone FR. Immunology: dangerous liaisons. Nature 2003; 425: 460–461.
- Cole GT, Kirkland TN, Franco M. Immunoreactivity of a surface wall fraction produced by spherules of Coccidioides immitis. Infect Immun 1988; 56: 2695–2701.
- Cole GT, Seshan KR, Franco M. Isolation and morphology of an immunoreactive outer wall fraction produced by spherules of Coccidioides immitis. Infect Immun 1988; 56: 2686–2694.
- Hung CY, Ampel NM, Christian L, Seshan KR, Cole GT. A major cell surface antigen of Coccidioides immitis which elicits both humoral and cellular immune responses. Infect Immun 2000; 68: 584–593.
- Hung C-Y, Yu J-J, Seshan KR, Reichard U, Cole GT. A parasitic phase-specific adhesin of Coccidioides immitis contributes to the virulence of this respiratory fungal pathogen. Infect Immun 2002; 70: 3443–3456.
- Tarbet JE, Breslau AM. Histochemical investigation of the spherule of Coccidioides immitis in relation to host reaction. J Infect Dis 1953; 72: 183–190.
- Kronenberg M. Presenting fats with SAPs. Nat Immunol 2004; 5: 126–127.
- Kang S-J, Cresswell P. Saposins facilitate CD id-restricted presentation of an exogenous lipid antigen to T cells. Nat Immunol 2004; 5: 175–181.
- Kawakami K, Yamamoto N, Kinjo Y Critical role of Valphal4+ natural killer T cells in the innate phase of host protection against Streptococcus pneumoniae infection. Eur J Immunol 2003; 33: 3322–3330.
- Zhou D, Cantu Cr, Sagiv Y. Editing of CD1d-bound lipid antigens by endosomal lipid transfer proteins. Science 2004; 303: 523–527.
- Exley MA, Bigley NJ, Cheng 0. Innate immune response to encephalomyocarditis virus infection mediated by CD1d. Im-munology 2003; 110: 519–526.
- Kumar H, Belperron A, Barthold SW, Bockenstedt LK. Cutting edge: CD1d deficiency impairs murine host defense against the spirochete, Borrelia burgdorferi . J Immunol 2000; 165: 4797–4801.
- Romani L, Mencacci A, Cenci E. Neutrophil production of IL-12 and IL-10 in candidiasis and efficacy of IL-12 therapy in neutropenic mice. J Immunol 1997; 158: 5349–5356.
- Jiang C, Magee DM, Quitugua TN, Cox RA. Genetic vaccina-tion against Coccidioides immitis: comparison of vaccine efficacy of recombinant antigen 2 and antigen 2 cDNA. Infect Immun 1999; 67: 630–635.
- Arulanandam BP, O'Toole M, Metzger DW. Intranasal inter-leukin-12 is a powerful adjuvant for protective mucosal immu-nity. J Infect Dis 1999; 180: 940–949.
- Janeway C, Travers P, Walport M, Schlomchick MJ. Immuno-biology: The Immune System in Health and Disease, 5th Ed. New York: Garland Publishing 2001; 69–74: 322–325.
- Fierer J, Walls L, Eckmann L, Yamamoto T, Kirkland TN. Importance of interleukin-10 in genetic susceptibility of mice to Coccidioides immitis. Infect Immun 1998; 66: 4397–4402.
- Wille U, Villegas EN, Craig L, Peach R, Hunter CA. Contribu-tion of interleukin-12 (IL-12) and the CD28/B7 and CD40/CD40 ligand pathways to the development of a pathological T-cell response in IL-10-deficient mice. Infect Immun 2002; 70: 6940–6947.
- Petkus AF, Baum LL. Natural killer cell inhibition of young spherules and endospores of Coccidioides immitis. J Immunol 1987; 139: 3107–3111.
- Shibuya A. Development and functions of natural killer cells. Int J Hematol 2003; 78: 1–6.
- Farag SS, VanDeusen JB, Fehniger TA, Caligiuri MA. Biology and clinical impact of human natural killer cells. Int J Hematol 2003; 78: 7–17.
- Mocikat R, Braumuller H, Gumy A. Natural killer cells activated by MHC class IL°w targets prime dendritic cells to induce protective CD8 T responses. Immunity 2003; 19: 561–569.
- Cain JA, Deepe GSJ. Evolution of the primary immune response to Histoplasma capsulatum in murine lung. Infect Immun 1998; 66: 1473–1481.
- Kurup VP, Xia JQ, Rickaby DA. Aspergillus fumigatus antigen exposure results in pulmonary airway resistance in wild-type but not in IL-4 knockout mice. Clin Immunol 1999; 90: 404–410.
- Cenci E, Mencacci A, Del Sero G. Interleukin-4 causes suscept-ibility to invasive pulmonary aspergillosis through suppression of protective type I responses. J Infect Dis 1999; 180: 1957–1968.
- Harley WB, Blaser MJ. Disseminated coccidioidomycosis asso-ciated with extreme eosinophilia. Clin Infect Dis 1994; 18: 627–629.
- Simon H-U. The neutralization of interleukin-5 as a therapeutic concept in allergic inflammation. Sarcoidosis Vasculitis and Diffuse Lung Diseases 2002; 19: 25–28.
- Foster PS, Hogan SP, Yang M. Interleukin-5 and eosinophils as therapeutic targets for asthma. Trends Mol Med 2002; 8: 162–167.
- Williams TJ. The eosinophil enigma. J Clin Invest 2004; 113: 507–509.
- Hamelmann E, Cieslewicz G, Schwarze J. Anti-interleukin 5 but not anti-IgE prevents airway inflammation and airway hyperre-sponsiveness. Am J Respir Grit Care Med 1999; 160: 934–941.
- Huffnagle GB, B BM, Street NE, Lipscomb ME IL-5 is required for eosinophil recruitment, crystal deposition, and mononuclear cell recruitment during a pulmonary Cryptococcus neoformans infection in genetically susceptible mice (C57BL/6). J Immunol 1998; 160: 2393–2400.
- Barton BE. IL-6: insights into novel biological activities. Clin Immunol Immunopathol 1997; 85: 16–20.
- Diehl S, Rincon M. The two faces of IL-6 on Thl/Th2 differentiation. Mol Immunol 2002; 39: 531–536.
- Nagabhushanam V, Solache A, Ting L-M. Innate inhibition of adaptive immunity: Mycobacterium tuberculosis - induced IL-6 inhibits macrophage responses to IFN-gamma. J Immunol 2003; 171: 4750–4757.
- Pasare C, Medzhitov R. Toll pathway-dependent blockade of CD4 +CD25+ T cell-mediated suppression by dendritic cells. Science 2003; 299: 1033–1036.
- Powrie F, Maloy K. Regulating the regulators. Science 2003; 299: 1030–1031.
- Hon i S, Nomura T, Sakaguchi S. Control of regulatory T cell development by the transcription factor Foxp3. Science 2003; 299: 1057–1061.
- Nagler-Anderson C, Bhan AK, Podolsky DK, Terhorst C. Control freaks: Immune regulatory cells. Nat Immunol 2004; 5: 119–122.
- Hisaeda H, Maekawa Y, Iwakawa D. Escape of malaria parasites from host immunity requires CD4+CD25+ regulatory T cells. Nat Med 2004; 10: 29–30.
- Belkaid Y, Piccirillo CA, Mendez S, Shevach EM, Sacks DL. CD4 +CD25+ regulatory T cells control Leishmania major persistence and immunity. Nature 2002; 420: 502–507.
- Gershon RK, Eardley DD, Durum S. Contrasuppression. A novel immunoregulatory activity. J Exp Med 1981; 153: 1533–1546.
- Casadevall A, Pirofski L-A. Host-pathogen interactions: redefin-ing the basic concepts of virulence and pathogenicity. Infect Immun 1999; 67: 3703–3713.
- Casadevall A, Pirofski L-A. What is a pathogen? Ann Intern Med 2002; 34: 2–4.
- Romani L, Bistoni F, Puccetti P. Fungi, dendritic cells and receptors: a host perspective of fungal virulence. Trends Micro-biol 2002; 10: 508–514.
- Montagnoli C, Bozza S, Bacci A. A role for antibodies in the generation of memory antifungal immunity. Eur J Immunol 2003; 33: 1193–1204.
- Galgiani JN, Isenberg RA, Stevens DA. Chemotaxigenic activity of extracts from the mycelial and spherule phases of Coccidioides immitis for human polymorphonuclearleukocytes. Infect Immun 1978; 21: 862–865.
- Casadevall A. Antibody-mediated immunity against intracellular pathogens: two-dimensional thinking comes full circle. Infect Immun 2003; 71: 4225–4228.
- Casadevall A, Cassone A, Bistoni F. Antibody and/or cell-mediated immunity, protective mechanisms in fungal disease: an ongoing dilemma or an unnecessary dispute? Med Mycol 1998; 36: 95–105.
- Schuh JM, Kunkel SL, Hogaboam CM. Mice knockouts for chemokines and chemokine receptors. In: Fantuzzi G (ed.). Contemporary Immunology: Cytokine Knockouts, 2nd ed.. To-towa NJ: Humana Press, Inc, 2003: 323–345.
- Power CA. Knock-out models to dissect chemokine receptor function in vivo. J Immunol Methods 2003; 273: 73–82.
- Traynor TR, Herring AC, Dorf ME. Differential roles of CC chemokine ligand 2/monocyte chemotactic protein-1 and CCR2 in the development of Ti immunity. J Immunol 2002; 168: 4659–4666.
- Forster R, Schubel A, Breitfeld D. CCR7 coordinates the primary immune response by establishing functional microenvir-onments in secondary lymphoid organs. Cell 1999; 99: 23–33.
- Peters W, Dupuis M, Charo IF. A mechanism for the impaired IFN-gamma production in C-C chemokine receptor 2 (CCR2) knockout mice: role of CCR2 in linking the innate and adaptive immune responses. J Immunol 2000; 165: 7072–7077.
- Sato N, Ahuja SK, Quinones M. CC chemokine receptor (CCR)2 is required for langerhans cell migration and localization of T helper cell type 1 (Th1)-inducing dendritic cells. Absence of CCR2 shifts the Leishmania major-resistant phenotype to a susceptible state dominated by Th2 cytokines, b cell outgrowth, and sustained neutrophilic inflammation. J Exp Med 2000; 192: 205–218.
- Kim CH, Nagata K, Butcher EC. Dendritic cells support sequential reprogramming of chemoattractant receptor profiles during naive to effector T cell differentiation. J Immunol 2003; 171: 152–158.
- Mosmann TR, Sad S, Krishnan L. Differentiation of subsets of CD4 + and CD8+ T cells. Ciba Found Symp 1995; 195: 42–50.
- Wuthrich M, Filutowicz HI, Warner T, Deepe GSJ, Klein BS. Vaccine immunity to pathogenic fungi overcomes the require-ment for CD4+ help in exogenous antigen presentation to CD8+ T cells: implications for vaccine development in immune-deficient hosts. J Exp Med 2003; 197: 1405–1416.
- Pearce EL, Mullen AC, Martins GA. Control of effector CD8+ T cell function by the transcription factor eomesodermin. Science 2003; 302: 1041–1043.
- Donnelly JJ. New developments in adjuvants. Mech Ageing Dev 1997; 93: 171–177.
- Chen H. Recent advances in mucosal vaccine development. J Controlled Release 2000; 67: 117–128.
- O'Hagan DT, Valiante NM. Recent advances in the discovery and delivery of vaccine adjuvants. Nature Rev Drug Discov 2003; 2: 727–735.
- Kirschning CJ, Wesche H, Merrill AT, Rothe M. Human toll-like receptor 2 confers responsiveness to bacterial lipopolysaccharide. J Exp Med 1998; 188: 2091–2097.
- Bihl F, Salez L, Beaubier M. Overexpression of Toll-like receptor 4 amplifies the host response to lipopolysaccharide and provides a survival advantage in transgenic mice. J Immunol 2003; 170: 6141–6150.
- Landmann R, Muller B, Zimmerli W CD14, new aspects of ligand and signal diversity. Microbes Infect 2000; 2: 295–304.
- Baldrick P, Richardson D, Elliott G, Wheeler AW. Safety evaluation of monophosphoryl lipid A (MPL): an immunosti-mulatory adjuvant. Regulatory Toxicol Pharmacol 2002; 35: 398–413.
- Skeiky YAW, Coler RN, Brannon M. Protective efficacy of a tandemly linked, multi-subunit recombinant leishmanial vaccine (Leish-111f) formulated in MPL adjuvant. Vaccine 2002; 20: 3292–3303.
- Petersen E, Nielsen HV, Christiansen L, Spenter J. Immunization with E. coli produced recombinant T gondii SAG1 with alum as adjuvant protect mice against lethal infection with Toxoplasma gondii. Vaccine 1998; 16: 1283–1289.
- Jiang C, Magee DM, Cox RA. Construction of a single-chain interleukin-12-expressing retroviral vector and its application in cytokine gene therapy against experimental coccidioidomycosis. Infect Immun 1999; 67: 2996–3001.
- Su Z, Tam M-F, Jankovic D, Stevenson MM. Vaccination with novel immunostimulatory adjuvants against blood-stage malaria in mice. Infect Immun 2003; 71: 5178–5187.
- Bozza S, Gaziano R, Lipford GB. Vaccination of mice against invasive aspergillosis with recombinant Aspergillus proteins and CpG oligodeoxynucleotides as adjuvants. Microbes Infect 2002; 4: 1281–1290.
- Jiang W, Pisetsky DS. Enhancing immunogenicity by CpG DNA. Curr Opin Mol Ther 2003; 5: 180–185.
- Gomis S, Babiuk L, Godson DL. Protection of chickens against Escherichia coli infections by DNA containing CpG motifs. Infect Immun 2003; 71: 857–863.
- Li K, Yu JJ, Hung CY, Lehmann PF, Cole GT. Recombinant urease and urease DNA of Coccidioides immitis elicit an immunoprotective response against coccidioidomycosis in mice. Infect Immun 2001; 69: 2878–2887.
- Delgado N, Xue J, Yu J-J, Hung C-Y, Cole GT. A recombinant beta-1,3-glucanosyltransferase homolog of Coccidioides posada-sii protects mice against coccidioidomycosis. Infect Immun 2003; 71: 3010–3019.
- Hemmi H, Takeuchi 0, Kawai T. A Toll-like receptor recognizes bacterial DNA. Nature 2000; 408: 740–745.
- Krieg AM. CpG motifs in bacterial DNA and their immune effects. Annu Rev Immunol 2002; 20: 709–760.
- Walker PS, Scharton-Kersten T, Krieg AM. Immunostimulatory oligodeoxynucleotides promote protective immunity and provide systemic therapy for leishmaniasis via IL-12- and IFN-gamma-dependent mechanisms. Proc Natl Acad Sci USA 1999; 96: 6970–6975.
- Chu RS, Targoni OS, Krieg AM, Lehmann PV, Harding CV. CpG oligodeoxynucleotides act as adjuvants that switch on T helper 1 (Thl) immunity. J Exp Med 1997; 186: 1623–1631.
- Heikenwalder M, Polymenidou M, Junt T. Lymphoid follicle destruction and immunosuppression after repeated CpG oligo-deoxynucleotide administration. Nat Med 2004; 10: 187–192.
- Engers H, Kieny MP, Malhotra P, Pink JR. Third meeting on novel adjuvants currently in or close to clinical testing World Health Organization. Vaccine 2003; 21: 3503–3524.
- Kirkland TN, Thomas PW, Finley F, Cole GT. Immunogenicity of a 48-kilodalton recombinant T-cell-reactive protein of Cocci-dioides immitis. Infect Immun 1998; 66: 424–431.
- Huang RP, Huang R, Fan Y, Lin Y. Simultaneous detection of multiple cytokines from conditioned media and patient's sera by an antibody-based protein array system. Anal Biochem 2001; 294: 55–62.
- Wang CC, Huang R-P, Sommer M. Array-based multiplexed screening and quantitation of human cytokines and chemokines. J Proteome Res 2002; 1: 337–343.
- Foxman EF, Zhang M, Hurst SD. Inflammatory mediators in uveitis: differential induction of cytokines and chemokines in ml- versus Th2-mediated ocular inflammation. J Immunol 2002; 168: 2483–2492.
- Hergenhahn M, Kenzelmann M, Grone H-J. Laser-controlled microdissection of tissues opens a window of new opportunities. Pathol Res Practice 2003; 199: 419–423.
- Zhu G, Xiao H, Mohan VP. Gene expression in the tuberculous granuloma: analysis by laser capture microdissection and real-time PCR. Cell Microbiol 2003; 5: 445–453.
- Ruchel R, Schaffrinski M, Seshan KR, Cole GT. Vital staining of fungal elements in deep-seated mycotic lesions during experi-mental murine mycoses using the parenterally applied optical brightener Blankophor. Med Mycol 2000; 38: 231–237.
- Luzzi V, Mahadevappa M, Raja R, Warrington JA, Watson MA. Accurate and reproducible gene expression profiles from laser capture microdissection, transcript amplification, and high density oligonucleotide microarray analysis. J Mol Diagn 2003; 5: 9–14.
- Appleyard RC, Ghosh P, Swain MV. Biomechanical, histological and immunohistological studies of patellar cartilage in an ovine model of osteoarthritis induced by lateral meniscectomy. Os-teoarthritis and Cartilage 1999; 7: 281–294.
- Lecara G, Cox RA, Simpson RB. Coccidioides immitis vaccine: potential of an alkali-soluble, water-soluble cell wall antigen. Infect Immun 1983; 39: 473–475.
- Dugger KO, Galgiani JN, Ampel NM. An immunoreactive apoglycoprotein purified from Coccidioides immitis. Infect Im-mun 1991; 59: 2245–2251.
- Zhu Y, Yang C, Magee DM, Cox RA. Coccidioides immitis antigen 2: analysis of gene and protein. Gene 1996; 181: 121–125.
- Zhu Y, Yang C, Magee DM, Cox RA. Molecular cloning and characterization of Coccidioides immitis antigen 2 cDNA. Infect Immun 1996; 64: 2695–2699.
- Huppert M, Spratt NS, Vukovich KR, Sun SH, Rice EH. Antigenic analysis of coccidioidin and spherulin determined by two-dimensional immunoelectrophoresis. Infect Immun 1978; 20: 541–551.
- Dugger KO, Villareal KM, Ngyuen A. Cloning and sequence analysis of the cDNA for a protein from Coccidioides immitis with immunogenic potential. Biochem Biophys Res Commun 1996; 218: 485–489.
- Proft T, Hilbert H, Layh-Schmitt G, Herrmann R. The proline-rich P65 protein of Mycoplasma pneumoniae is a component of the Triton X-100-insoluble fraction and exhibits size polymorph-ism in the strains M129 and FH. J Bacteriol 1995; 177: 3370–3378.
- Galgiani JM, Peng T, Lweis ML. Cerebrospinal fluid antibodies detected by ELISA against a 33-kDa antigen from spherules of © 2004 SHAM, Medical Mycology, 42, 189-216 Coccidioides immitis in patients with coccidioidal meningitis. J Infect Dis 1996; 173: 499–502.
- Zhu Y, Tryon V, Magee DM, Cox RA. Identification of a Coccidioides immitis antigen 2 domain that expresses B-cell-reactive epitopes. Infect Immun 1997; 65: 3376–3380.
- Wieden MA, Lundergan LL, Blum J. Detection of coccidioidal antibodies by 33-kDa spherule antigen, Coccidioides EIA, and standard serologic tests in sera from patients evaluated for coccidioidomycosis. J Infect Dis 1996; 173: 1273–1277.
- Kirkland TN, Finley F, Orsbom KI, Galgiani JN. Evaluation of the proline-rich antigen of Coccidioides immitis as a vaccine candidate in mice. Infect Immun 1998; 66: 3519–3522.
- Peng T, Orsbom KI, Orbach MJ, Galgiani JN Proline-rich vaccine candidate antigen of Coccidioides immitis: conservation among isolates and differential expression with spherule matura-tion. J Infect Dis 1999; 179: 518–521.
- Galgiani JN, Sun SH, Dugger KO. An arthroconidial-spherule antigen of Coccidioides immitis: differential expression during in vitro fungal development and evidence for humoral response in humans after infection or vaccination. Infect Immun 1992; 60: 2627–2635.
- Peng T, Shubitz L, Simons J. Localization within a proline-rich antigen (Ag2/PRA) of protective antigenicity against infection with Coccidioides immitis in mice. Infect Immun 2002; 70: 3330–3335.
- Jiang C, Magee DM, Ivey FD, Cox RA. Role of signal sequence in vaccine-induced protection against experimental coccidioido-mycosis. Infect Immun 2002; 70: 3539–3545.
- Kim KI, Leung AN, Flint JD, Muller NL. Chronic pulmonary coccidioidomycosis: computed tomographic and pathologic findings in 18 patients. Can Assoc Rad J 1998; 49: 401–407.
- Jiao X, Lo-Man R, Winter N. The shift of Thl to Th2 immunodominance associated with the chronicity of Mycobac-terium bovis bacille Calmette-Guerin infection does not affect the memory response. J Immunol 2003; 170: 1392–1398.
- Yu J-J, Shubitz LF, Peng T. Protection of mice against intraperitoneal or intranasal Coccidioides infection by recombi-nant Coccidioides- specific antigen (CSA) and antigen 2/PrA (Ag2/PRA), singly and in combination. In: 103rd General Meeting of the American Society for Microbiology, Washington, D.C., May 18–22, 2003; F-111, p. 293.
- Yang W, Jackson DC, Zeng Q, McManus DR Multi-epitope schistosome vaccine candidates tested for protective immuno-genicity in mice. Vaccine 2000; 19: 103–113.
- Wyckoff EE, Pishko EJ, Kirkland TN, Cole GT. Cloning and expression of a gene encoding a T-cell reactive protein from Coccidioides immitis: homology to 4-hydroxyphenylpyruvate dioxygenase and the mammalian F antigen. Gene 1995; 161: 107–111.
- Thomas PW, Wyckoff EE, Pishko EJ. The hsp60 gene of the human pathogenic fungus Coccidioides immitis encodes a T-cell reactive protein. Gene 1997; 199: 83–91.
- Huygen K. On the use of DNA vaccines for the prophylaxis of mycobacterial diseases. Infect Immun 2003; 71: 1613–1621.
- Seder RA, Mascola JR. Immunology: Basic immunology of vaccine development. In: Bloom BR, Lambert PH (eds). The Vaccine Book. San Diego: Academic Press, 2003: 51–93.
- Ivey FD, Magee DM, Woitaske MD, Johnson SA, Cox RA. Identification of a protective antigens of Coccidioides immitis by expression library immunization. Vaccine 2003; 21: 4359–4367.
- Delgado N, Hung C-Y, Tarcha E, Cole GT. Profiling gene expression in Coccidioides posadasii. Med Mycol 2004; 42: 59–71.
- Altschul SF, Madden TL, Schaffer AA. Gapped BLAST and PSI-BLAST: A new generation of protein database search programs. Nucleic Acids Res 1997; 25: 3389–3402.
- Wheeler DL, Chappey C, Lash AE. Database resources of the National Center for Biotechnology Information. Nucleic Acids Res 2000; 28: 10–14.
- Delcher AL, Harmon D, Kasif S, White 0, Salzberg SL. Improved microbial gene identification with GLIMMER. Nu-cleic Acids Res 1999; 27: 4636–4641.
- de Groot PW, Ruiz JC, de Aldana RV. A genomic approach for the identification and classification of genes involved in cell wall formation and its regulation in Saccharomyces cerevisiae. Comp Funct Genome 2001; 2: 124–142.
- Hwang L, Hocking-Murray D, Bahrami AK. Identifying phase-specific genes in the fungal pathogen Histoplasma capsulatum using a genomic shotgun microarray. Mol Biol Cell 2003; 14: 2314–2326.
- Sampson SL, Rengarajan J, Rubin EJ. Bacterial genomics and vaccine design. Expert Rev Vaccines 2003; 2: 437–445.
- Rappuoli R, Covacci A. Reverse vaccinology and genomics. Science 2003; 302: 602.
- Zimmermann CR, Johnson SM, Martens GW. Protection against lethal murine coccidioidomycosis by a soluble vaccine from spherules. Infect Immun 1998; 66: 2342–2345.
- Bruneau JM, Magnin T, Tagat E. Proteome analysis of Aspergillus fumigatus identifies glycosylphosphatidylinositol—anchored proteins associated to the cell wall biosynthesis. Electrophoresis 2001; 22: 2812–2823.
- Johnson SM, Kerekes KM, Zimmermann CR, Williams RH, Pappagianis D. Identification and cloning of an aspartyl proteinase from Coccidioides immitis. Gene 2000; 241: 213–222.
- Reichard U, Monod M, Odds F, Ruchel R. Virulence of an aspergillopepsin-deficient mutant of Aspergillus fumigatus and evidence for another aspartic proteinase linked to the fungal cell wall. J Med Vet Mycol 1997; 35: 189–196.
- Verity CK, McManus DP, Brindley PJ. Vaccine efficacy of recombinant cathepsin D aspartic protease from Schistosoma japonicum. Parasite Immunol 2001; 23: 153–162.
- Verity CK, McManus DP, Brindley PJ. Cellular responses to Schistosoma japonicum cathepsin D aspartic protease. Parasite Immunol 2002; 24: 363–367.