Genetic and respiratory tract risk factors for aspergillosis: ABPA and asthma with fungal sensitization

References

• Greenberger PA. Allergic bronchopulmonary aspergillosis. Allergy: Principles and Practice, NF Adkinson, JW Yunginer, WW Busse, BS Bochner, ST Holgate, FER Simons. Mosby, St. Louis 2003; 1353–1371
   Google Scholar
• Stevens, DA, Moss, R, Kurup, VP, et al. Allergic bronchopulmonary aspergillosis in cystic fibrosis: Cystic Fibrosis Foundation Consensus Conference. Clin Infect Dis 2003; 37: S225–S264.
   Web of Science ®Google Scholar
• Knutsen AP. Immunopathogenesis of allergic bronchopulmonary aspergillosis. Frontiers in Bioscience 2003; 8: 589–602
   Web of Science ®Google Scholar
• Slavin RG, Bedrossian CW, Hutcheson PS, et al. A pathologic study of allergic bronchopulmonary aspergillosis. J Allergy Clin Immunol 1988; 81: 718–725
   PubMed Web of Science ®Google Scholar
• Paris S, Boisvieux-Ulrich E, Crestani B, et al. Internalization of Aspergillus fumigatus conidia by epithelial and endothelial cells. Infect Immun 1997; 65: 1510–1514
   PubMed Web of Science ®Google Scholar
• Schaffner A, Douglas H, Braude A. Selective protection against conidia by mononuclear and mycelia by polymorphonuclear phagocytes in resistance to Aspergillus: observations on these two lines of defense in vivo and in vitro with human and mouse phagocytes. J Clin Invest 1982; 69: 617–631
   PubMed Web of Science ®Google Scholar
• Roilides E, Uhlig K, Venzon D, Pizzo PA, Walsh TJ. Prevention of corticosteroid-induced suppression of human polymorphonuclear leukocyte-induced damage of Aspergillus fumigatus hyphae by granulocyte colony-stimulating factor and gamma interferon. Infect Immun 1993; 61: 4870–4877
   PubMed Web of Science ®Google Scholar
• Brummer E, Maqbool A, Stevens DA. Protection of bronchoalveolar macrophages by GM-CSF against dexamethasone suppression of fungicidal activity for Aspergillus fumigatus conidia. Med Mycol 2001; 39: 509–515
   PubMed Web of Science ®Google Scholar
• Brummer E, Maqbool A, Stevens DA. In vivo granulocyte macrophage colony-stimulating factor prevents dexamethasone suppression of killing of Aspergillus fumigatus by broncho-alveolar macrophages. J Leukocyte Biol 2001; 70: 868–872
   PubMed Web of Science ®Google Scholar
• Kauffman HF, Tomee JF. Inflammatory cells and airway defense against Aspergillus fumigatus. Immunol Allergy Clin N Am 1998; 18: 619–640
   Web of Science ®Google Scholar
• Tomee JF, Kauffman HF. Putative virulence factors of Aspergillus fumigatus. Clin Exp Allergy 2000; 30: 476–484
   Google Scholar
• Tomee JF, Kauffman HF, Klimp AH, et al. Immunologic significance of a collagen-derived culture filtrate containing proteolytic activity in Aspergillus-related diseases. J Allergy Clin Immunol 1994; 93: 768–778
   PubMed Web of Science ®Google Scholar
• Tomee JF, van der Werf TS, Latge JP, et al. Serologic monitoring of disease and treatment in a patient with pulmonary aspergilloma. Am J Respir Crit Care Med 1995; 151: 199–204
   PubMed Web of Science ®Google Scholar
• Kauffman HF, Tomee JF, van de Riet MA, Timmerman AJ, Borger P. Protease-dependent activation of epithelial cells by fungal allergens leads to morphologic changes and cytokine production. J Allergy Clin Immunol 2000; 105: 1185–1193
   PubMed Web of Science ®Google Scholar
• Robinson BW, Venaille TJ, Mendis AH, McAleer R. Allergens as proteases: an Aspergillus fumigatus proteinase directly induces human epithelial cell detachment. J Allergy Clin Immunol 1990; 86: 726–731
   PubMed Web of Science ®Google Scholar
• Herbert CA, King CM, Ring PC, et al. Augmentation of permeability in the bronchial epithelium by the house dust mite allergen Der p1. Am J Respir Cell Mol Biol 1995; 12: 369–378
   PubMed Web of Science ®Google Scholar
• Chauhan B, Santiago L, Hutcheson PS, et al. Evidence for the involvement of two different MHC class II regions in susceptibility or protection in allergic bronchopulmonary aspergillosis. J Allergy Clin Immunol 2000; 106: 723–729
   PubMed Web of Science ®Google Scholar
• Chauhan B, Santiago L, Kirschmann DA, et al. The association of HLA-DR alleles and T-cell activation with allergic bronchopulmonary aspergillosis. J Immunol 1997; 159: 4072–4076
   PubMed Web of Science ®Google Scholar
• Chauhan BA, Knutsen AP, Hutcheson PS, Slavin RG, Bellone CJ. T cell subsets, epitope mapping, and HLA-restriction in patients with allergic bronchopulmonary aspergillosis. J Clin Invest 1996; 97: 2324–2331
   PubMed Web of Science ®Google Scholar
• Verhoef A, Higgins JA, Thorpe CJ, et al. Clonal analysis of the atopic immune response to the group 2 allergen of Dermatophagoides spp.: identification of HLA-DR and -DQ restricted T cell epitopes. Inter Immunol 1993; 5: 1589–1597
   PubMed Web of Science ®Google Scholar
• Lamb JR, Higgins JA, Hetzel C, et al. The effects of changes at peptide residues contacting MHC class II T-cell receptor on antigen recognition and human Th0 cell effector function. Immunology 1995; 85: 447–454
   PubMed Web of Science ®Google Scholar
• Tsitoura DC, Verhoef A, Gelder CM, O'Hehir RE, Lamb JR. Altered T cell ligands derived from a major house dust mite allergen enhance IFN-γ but not IL-4 production by human CD4+ T cells. J Immunol 1996; 157: 2160–2165
   PubMed Web of Science ®Google Scholar
• Pfeiffer C, Stein J, Southwood S, et al. Altered peptide ligands can control CD4 T lymphocyte differentiation in vivo. J Exp Med 1995; 181: 1569–1574
   PubMed Web of Science ®Google Scholar
• Evavold BD, Sloan-Lancaster J, Hsu BL, Allen PM. Separation of T helper 1 clone cytolysis from proliferation and lymphokine production using analog peptides. J Immunol 1993; 150: 3131–3140
   PubMed Web of Science ®Google Scholar
• Racioppi L, Ronchese F, Matis LA, Germain RN. Peptide-major histocompatibility complex class II complexes with agonist/antagonist properties provide evidence for ligand related differences in T cell receptor dependent intracellular signaling. J Exp Med 1993; 177: 1047–1060
   PubMed Web of Science ®Google Scholar
• Idzko M, La Sala A, Ferrari D, et al. Expression and function of histamine receptors in human monocyte-derived dendritic cells. J Allergy Clin Immunol 2002; 109: 839–846
   PubMed Web of Science ®Google Scholar
• Reefer AJ, Carneiro RM, Custis NJ, et al. A role for IL-10-mediated HLA-DR7-restricted T cell-dependent events in development of the modified Th2 response to cat allergen. J Immunol 2004; 172: 2763–2772
   PubMed Web of Science ®Google Scholar
• Knutsen AP. Immune responses in allergic bronchopulmonary aspergillosis and fungal allergy. Mold Allergy, Biology and Pathogenesis, VP Kurup. Research Signpost, KeralaIndia 2005; 209–235
   Google Scholar
• Izuhara K, Yanagihara Y, Hamasaki N, Shirakawa T, Hopkin JM. Atopy and the human IL-4 receptor a chain. J Allergy Clin Immunol 2000; 106: S65–71
   PubMed Web of Science ®Google Scholar
• Nelms K, Keegan AD, Zamorano J, Ryan JJ, Paul WE. The IL-4 receptor: signaling mechanisms and biologic functions. Annu Rev Immunol 1999; 17: 701–738
   PubMed Web of Science ®Google Scholar
• Hershey GK. IL-13 receptors and signaling pathways: an evolving web. J Allergy Clin Immunol 2003; 111: 677–690
   PubMed Web of Science ®Google Scholar
• Walter DM, McIntire JJ, Berry G, et al. Critical role for IL-13 in the development of allergen-induced airway hyperreactivity. J Immunol 2001; 167: 4668–4675
   PubMed Web of Science ®Google Scholar
• Bernstein JA. Genetic association studies: what are they teaching clinicians. J Allergy Clin Immunol 2003; 111: 465–466
   PubMed Web of Science ®Google Scholar
• Liu X, Beaty TH, Deindl P, et al. Associations between total serum IgE levels and the 6 potentially functional variants with the genes IL-4, IL-13, and IL-4RA in German children: the German Multicenter Atopy Study. J Allergy Clin Immunol 2003; 112: 382–388
   PubMed Web of Science ®Google Scholar
• Codlin S, Soh C, Lee T, Lavender P. Characterization of a palindromic enhancer element in the promotors of IL4, IL5, and IL13 cytokine genes. J Allergy Clin Immunol 2003; 111: 826–832
   PubMed Web of Science ®Google Scholar
• Hershey GKK, Friedrich MF, Esswein LA, Thomas ML, Chatila TA. The association of atopy with a gain-of-function mutation in the α subunit of the interleukin-4 receptor. N Engl J Med 1997; 337: 1720–1725
   PubMed Web of Science ®Google Scholar
• Ober C, Leavitt SA, Tsalenko A, et al. Variation in the interleukin 4-receptor a gene confers susceptibility to asthma and atopy in ethnically diverse populations. Am J Hum Genet 2000; 66: 517–526
   PubMed Web of Science ®Google Scholar
• Chen W, Ericksen MB, Hershey GKK. Functional effect of the R110Q IL13 genetic variant alone and in combination with IL4RA genetic variants. J Allergy Clin Immunol 2004; 114: 553–560
   PubMed Web of Science ®Google Scholar
• Chen W, Daines MO, Hershey GKK. Turning off signal transducer and activator of transcription (STAT): the negative regulation of STAT signaling. J Allergy Clin Immunol 2004; 114: 476–489
   PubMed Web of Science ®Google Scholar
• Knutsen, AP, Amin, RS, Temprano, J, Wilmott, RW. Hypersensitivity pneumonitis and eosinophilic pulmonary diseases. In:. Chernick, V, Boat, T, Wilmott, R, Bush, V, (eds), Kendig's Disorders of the Respiratory Tract in Children, 7th edn. Saunders Elsevier Inc: Philadelphia, 2005, Ch. 49.
   Google Scholar
• Knutsen AP, Kariuki B, Consolino JD, Warrier MR. IL-4 alpha chain receptor (IL-4Ra) polymorphisms in allergic bronchopulmonary aspergillosis. Clin Mol Allergy 2006; 3: 1–6
   Google Scholar
• Khan SP, McClellan JS, Knutsen AP. Increased sensitivity to IL-4 in patients with allergic bronchopulmonary aspergillosis and atopy. Inter Arch Allergy Immunol 2000; 123: 319–326
   PubMed Web of Science ®Google Scholar
• Knutsen AP, Hutcheson PS, Albers GM, et al. Increased sensitivity to IL-4 in cystic fibrosis patients with allergic bronchopulmonary aspergillosis. Allergy 2003; 58: 81–87
   Google Scholar
• Knutsen AP, Chauhan B, Slavin RG. Cell-mediated immunity in allergic bronchopulmonary aspergillosis. Immunol Allergy Clin N Am 1998; 18: 575–599
   Web of Science ®Google Scholar
• Reljic R, Cosentino G, Gould HJ. Function of CD23 in the response of human B cells to antigen. Eur J Immunol 1997; 27: 572–575
   PubMed Web of Science ®Google Scholar
• Bonnefoy JY, Gauchat JF, Life P, et al. Regulation of IgE synthesis by CD23/CD21 interaction. Inter Arch Allergy Immunol 1995; 107: 40–42
   PubMed Web of Science ®Google Scholar
• Yoshimoto T, Bendelac A, Watson C, Hu-Li J, Paul WE. Role of NK1.1+ T cells in a Th2 response and in immunoglobulin E production. Science 1995; 270: 1845–1847
   PubMed Web of Science ®Google Scholar
• Bonnefoy JY, Gauchat JF, Life P, et al. Pairs of surface molecules involved in human IgE regulation: CD23-CD21 and CD40-CD40L. Eur Resp J ; : S 1996; 22: 63S–66
   Google Scholar
• Armant M, Rubio M, Delespesse G, Sarfati M. Soluble CD23 directly activates monocytes to contribute to the antigen-independent stimulation of resting T cells. J Immunol 1995; 155: 4868–4875
   PubMed Web of Science ®Google Scholar
• Jeannin P, Delneste Y, Lecoanet-Henchoz S, et al. CD86 (B7-2) on human B cells. A functional role in proliferation and selective differentiation into IgE- and IgG4-producing cells. J Biol Chem 1997; 272: 15613–15619
   PubMed Web of Science ®Google Scholar
• Nakajima A, Watanabe N, Yoshino S, et al. Requirement of CD28-CD86 co-stimulation in the interaction between antigen-primed T helper type 2 and B cells. Inter Immunol 1997; 9: 637–644
   PubMed Web of Science ®Google Scholar
• Jirapongsananuruk O, Hofer MF, Trumble AE, Norris DA, Leung DY. Enhanced expression of B7.2 (CD86) in patients with atopic dermatitis: a potential role in the modulation of IgE synthesis. J Immunol 1998; 160: 4622–4627
   PubMed Web of Science ®Google Scholar
• Haczku A, Takeda K, Redai I, et al. Anti-CD86 (B7.2) treatment abolishes allergic airway hyperresponsiveness in mice. Am J Resp Crit Care Med 1999; 159: 1638–1643
   PubMed Web of Science ®Google Scholar
• Jiang GZ, Kato Y, Sugiyama T, et al. Role of CD86 (B7-2) in triggering of antigen-specific IgE antibody response by lipopolysaccharide. FEMS Immunol Med Microbiol 1998; 21: 303–311
   PubMedGoogle Scholar
• Huang Y, Watanabe N, Ohtomo H. The involvement of CD80 and CD86 costimulatory molecules in the induction of eosinophilia in mice infected with Nippostrongylus brasiliensis. Inter Arch Allergy Immunol 1998; 117(Suppl. 1)2–4
   PubMedGoogle Scholar
• Tsuyuki T, Tsuyuki J, Einsle K, Kopf M, Coyle AJ. Costimulation through B7-2 (CD86) is required for the induction of a lung mucosal T helper cell 2 (TH2) immune response and altered airway responsiveness. J Exp Med 1997; 185: 1671–1679
   PubMed Web of Science ®Google Scholar
• Nakada M, Nishizaki K, Yoshino T, et al. CD80 (B7-1) and CD86 (B7-2) antigens on house dust mite-specific T cells in atopic disease function through T-T interactions. J Allergy Clin Immunol 1999; 104: 222–227
   PubMed Web of Science ®Google Scholar
• Gause WC, Ekkens M, Nguyen D, et al. The development of CD4+ T effector cells during the type 2 immune response. Immunol Res 1999; 20: 55–65
   PubMed Web of Science ®Google Scholar
• Jirapongsananuruk O, Leung DY. The modulation of B7.2 and B7.1 on B cells by immunosupressive agents. Clin Exp Immunol 1999; 118: 1–8
   PubMed Web of Science ®Google Scholar
• Allam J-P, Novak N, Fuchs C, et al. Characterization of dendritic cells from human oral mucosa: a new Langerhan's cell type with high constitutive FCE R1 expression. J Allergy Clin Immunol 2003; 112: 141–148
   PubMed Web of Science ®Google Scholar
• Idzko M, la Sala A, Ferrari D, et al. Expression and function of histamine receptors in human monocyte-derived dendritic cells. J Allergy Clin Immunol 2002; 109: 839–846
   PubMed Web of Science ®Google Scholar
• Hammad H, Charbonnier A-S, Dueg C, et al. Th2 polarization by Der p1-pulsed monocyte-derived dendritic cells is due to the allergic status of the donors. Blood 2001; 98: 1135–1141
   PubMed Web of Science ®Google Scholar
• Akbari O, DeKruyff RH, Umetsu DT. Pulmonary dendritic cells producing IL-10 moderate tolerance induced by respiratory exposure to antigen. Nature Immunol 2001; 2: 725–731
   PubMed Web of Science ®Google Scholar
• Akdis CA, Blaser K. Histamine in the immune regulation of allergic inflammation. J Allergy Clin Immunol 2003; 112: 15–22
   PubMed Web of Science ®Google Scholar
• Elenkov IJ, Webster E, Papanicolaou DA, Fleisher TA, Chrousos GP, Wilder RL. Histamine potently suppresses human IL-12 and stimulates IL-10 production via H2 receptors. J Immunol 1998; 161: 2586–2593
   PubMed Web of Science ®Google Scholar
• Umetsu DT, Akbari O, DeKruyff RH. Regulator T cells control the development of allergic disease and asthma. J Allergy Clin Immunol 2003; 112: 480–487
   PubMed Web of Science ®Google Scholar
• Rosenwasser LJ, Busse WW, Lizambri RG, Olejnik TA, Totoritis MC. Allergic asthma and an anti-CD23 mAb (IDEC-152): results of a phase 1, Single-dose, escalating clinical trial. J Allergy Clin Immunol 2003; 112: 563–570
   PubMed Web of Science ®Google Scholar
• Poole JA, Meng J, Reff M, Spellman MC, Rosenwasser LJ. Anti-CD23 monoclonal antibody, lumiliximab, inhibited allergen-induced responses in antigen-presenting cells and T cells from atopic subjects. J Allergy Clin Immunol 2005; 116: 780–788
   PubMed Web of Science ®Google Scholar
• Knutsen AP, Mueller KR, Hutcheson PS, Slavin RG. T- and B-cell dysregulation in cystic fibrosis patients with allergic bronchopulmonary aspergillosis. Clin Immunol Immunopath 1990; 55: 129–138
   PubMedGoogle Scholar
• Kurup VP, Pillai RR, Manickam P. Gene expression in murine model of allergic bronchopulmonary aspergillosis. Immunity Infect 2005; 73: 4381–4384
   PubMed Web of Science ®Google Scholar
• Vladich FD, Brazille SM, Stern D, et al. IL-13 R130Q, a common variant associated with allergy and asthma, enhances effector mechanisms essential for human allergic inflammation. J Clin Invest 2005; 115: 747–754
   PubMed Web of Science ®Google Scholar
• Davies DE, Wicks J, Powell RM, Puddicombe SM, Holgate ST. Airway remodeling in asthma: new insights. J Allergy Clin Immunol 2003; 111: 215–225
   PubMed Web of Science ®Google Scholar
• Chakir J, Shannon J, Molet S, et al. Airway remodeling-associated mediators in moderate to severe asthma: effect of steroids on TGF-β, IL-11, IL-17 and type I and type III collagen expression. J Allergy Clin Immunol 2003; 111: 1293–1298
   PubMed Web of Science ®Google Scholar
• Lordan JL, Davies DE, Wilson SJ, et al. The role of CD28-B7 costimulation in allergen-induced cytokine release by bronchial mucosa from patients with moderately severe asthma. J Allergy Clin Immunol 2001; 108: 976–981
   PubMed Web of Science ®Google Scholar
• Mullings RE, Wilson SJ, Puddicombe SM, et al. Singal transducer and activator of transcription (STAT-6) expression and function in asthmatic bronchial epithelium. J Allergy Clin Immunol 2001; 108: 832–838
   PubMed Web of Science ®Google Scholar
• Reed CE, Kita H. The role of protease activation of inflammation in allergic respiratory diseases. J Allergy Clin Immunol 2004; 114: 997–1008
   PubMed Web of Science ®Google Scholar
• Karjalainen J, Hulkkonen J, Nieminen MM, et al. Interleukin-10 gene promoter region polymorphism is associated with eosinophil count and circulating immunoglobulin E in adult asthma. Clin Exp Allergy 2003; 33: 78–83
   PubMed Web of Science ®Google Scholar
• Brouard J, Knauer N, Boelle P-Y, et al. Influence of interleukin-10 on airways colonization by Aspergillus fumigatus in cystic fibrosis patients. J Infect Dis 2005; 191: 1988–1991
   PubMed Web of Science ®Google Scholar
• De Waal Malefyt R, Figdor CG, de Vries JE. Regulation of human monocyte functions by Interleukin-10. Interleukin-10, JE de Vries, R de Waal-Malefyt. Springer-Verlag, Heidelberg 1995; 37–52
   Google Scholar
• Grünig G, Corry DB, Leach MW, et al. Interleukin-10 is a natural suppressor of cytokine production and inflammation in a murine model of allergic bronchopulmonary aspergillosis. J Exp Med 1997; 185: 1089–1099
   PubMed Web of Science ®Google Scholar
• Cousins DJ, Lee TH, Staynov DZ. Cytokine coexpression during human Th1/Th2 cell differentiation: direct evidence for coordinated expression of Th2 cytokines. J Immunol 2002; 169: 2498–2506
   PubMed Web of Science ®Google Scholar
• Elenkov IJ, Webster E, Papanicolaou DA, et al. Histamine potently suppresses human IL-12 and stimulates IL-10 production via H2 receptors. J Immunol 1998; 161: 2586–2593
   PubMed Web of Science ®Google Scholar
• Steele C, Rapaka RR, Metz A, et al. The beta-glucan receptor dectin-1 recognizes specific morphologies of Aspergillus fumigatus. PLoS Pathog 2005; 1: 323–334
   Web of Science ®Google Scholar