References
- Bok JW, Balajee SA, Marr KA, et al. LaeA, a regulator of virulence determinants in Aspergillus fumigatus. Eukaryot. Cell. 2005; 4: 1574–1582
- Denning DW, Stevens DA. Antifungal and surgical treatment of invasive aspergillosis: review of 2,121 published cases. Rev Infect Dis 1990; 12: 1147–1201
- Lin SJ, Schranz J, Teutsch SM. Aspergillosis case-fatality rate: systematic review of the literature. Clin Infect Dis 2001; 32: 358–366
- Patterson TF, Kirkpatrick WR, White M, et al. Invasive aspergillosis. Disease spectrum, treatment practices, and outcomes. I3 Aspergillus Study Group. Medicine (Baltimore) 2000; 79: 250–260
- Stevens DA, Kan VL, Judson MA, et al. Practice guidelines for diseases caused by Aspergillus. Infectious Diseases Society of America. Clin Infect Dis 2000; 30: 696–709
- Hogan LH, Klein BS, Levitz SM. Virulence factors of medically important fungi. Clin Microbiol Rev 1996; 9: 469–488
- Jahn B, Boukhallouk F, Lotz J, et al. Interaction of human phagocytes with pigmentless Aspergillus conidia. Infect Immun 2000; 68: 3736–3739
- Jahn B, Koch A, Schmidt A, et al. Isolation and characterization of a pigmentless-conidium mutant of Aspergillus fumigatus with altered conidial surface and reduced virulence. Infect Immun 1997; 65: 5110–5117
- Latge JP. Aspergillus fumigatus and aspergillosis. Clin Microbiol Rev 1999; 12: 310–350
- Tsai HF, Chang YC, Washburn RG, et al. The developmentally regulated alb1 gene of Aspergillus fumigatus: its role in modulation of conidial morphology and virulence. J Bacteriol 1998; 180: 3031–3038
- Tsai HF, Washburn RG, Chang YC, et al. Aspergillus fumigatus arp1 modulates conidial pigmentation and complement deposition. Mol Microbiol 1997; 26: 175–183
- Tsai HF, Wheeler MH, Chang YC, et al. A developmentally regulated gene cluster involved in conidial pigment biosynthesis in Aspergillus fumigatus. J Bacteriol 1999; 181: 6469–6477
- Bennett JW, Klich M. Mycotoxins. Clin Microbiol Rev 2003; 16: 497–516
- Nielsen KF, Smedsgaard J. Fungal metabolite screening: database of 474 mycotoxins and fungal metabolites for dereplication by standardised liquid chromatography-UV-mass spectrometry methodology. J Chromatogr A 2003; 1002: 111–136
- Grovel O, Pouchus YF, Robiou du Pont T, et al. Ion trap MS(n) for identification of gliotoxin as the cytotoxic factor of a marine strain of Aspergillus fumigatus Fresenius. J Microbiol Methods 2002; 48: 171–179
- Nieminen SM, Maki-Paakkanen J, Hirvonen MR, et al. Genotoxicity of gliotoxin, a secondary metabolite of Aspergillus fumigatus, in a battery of short-term test systems. Mutat Res 2002; 520: 161–170
- Kweon YO, Paik YH, Schnabl B, et al. Gliotoxin-mediated apoptosis of activated human hepatic stellate cells. J Hepatol 2003; 39: 38–46
- Suen YK, Fung KP, Lee CY, et al. Gliotoxin induces apoptosis in cultured macrophages via production of reactive oxygen species and cytochrome c release without mitochondrial depolarization. Free Radic Res 2001; 35: 1–10
- Bok JW, Keller NP. LaeA, a regulator of secondary metabolism in Aspergillus spp. Eukaryot Cell 2004; 3: 527–535
- Zhang Y-Q, Wilkinson H, Keller NP, . Secondary metabolite gene clusters. Handbook of Industrial Microbiology, Z An, et al. Marcel Dekker, New York 2004; 355–386
- Fernandes M, Keller NP, Adams TH. Sequence-specific binding by Aspergillus nidulans AflR, a C6 zinc cluster protein regulating mycotoxin biosynthesis. Mol Microbiol 1998; 28: 1355–1365
- Pedley KF, Walton JD. Regulation of cyclic peptide biosynthesis in a plant pathogenic fungus by a novel transcription factor. Proc Natl Acad Sci U S A 2001; 98: 14174–14179
- Proctor RH, Hohn TM, McCormick SP, et al. Tri6 encodes an unusual zinc finger protein involved in regulation of trichothecene biosynthesis in Fusarium sporotrichioides. Appl Environ Microbiol 1995; 61: 1923–1930
- Calvo AM, Wilson RA, Bok JW, et al. Relationship between secondary metabolism and fungal development. Microbiol Mol Biol Rev 2002; 66: 447–459
- Keller NP, Turner G, Bennett JW. Fungal secondary metabolism: from biochemistry to genomics. Nat Rev Microbio 2005; 3: 937–47
- Gardiner DM, Howlett BJ. Bioinformatic and expression analysis of the putative gliotoxin biosynthetic gene cluster of Aspergillus fumigatus. FEMS Microbiol Lett 2005; 248: 241–248
- Bok J-W, Hoffmeister D, Maggio-Hall L, et al. Genomic mining for Aspergillus natural products. Chemistry & Biology 2006; 13: 31–37
- Herbert RB. The Biosynthesis of Secondary Metabolites. Chapman and Hall, London 1989
- Gardiner DM, Cozijnsen AJ, Wilson LM, et al. The sirodesmin biosynthetic gene cluster of the plant pathogenic fungus Leptosphaeria maculans. Mol Microbiol 2004; 53: 1307–1318