968
Views
0
CrossRef citations to date
0
Altmetric
Infectious Diseases

Impact of Ebola epidemics on the daily operation of existing systems in Eastern Democratic Republic of the Congo: a brief review

ORCID Icon, , , &
Pages 184-192 | Received 16 Oct 2023, Accepted 10 Jan 2024, Published online: 22 Jan 2024

References

  • Mukadi-Bamuleka D, Bulabula-Penge J, Jacobs BKM, et al. Head-to-head comparison of diagnostic accuracy of four Ebola virus disease rapid diagnostic tests versus GeneXpert® in Eastern Democratic Republic of the Congo outbreaks: a prospective observational study. EBioMedicine. 2023;91:104568. doi:10.1016/j.ebiom.2023.104568.
  • Malvy D, McElroy AK, de Clerck H, et al. Ebola virus disease. Lancet. 2019;393(10174):936–948. doi:10.1016/S0140-6736(18)33132-5. Epub 2019 Feb 15. Erratum in: lancet. 2019;393(10185):2038.
  • Moran Z, Rodriguez W, Ahmadou D, et al. Comparative performance study of three Ebola rapid diagnostic tests in Guinea. BMC Infect Dis. 2020;20(1):670. doi:10.1186/s12879-020-05339-2.
  • Jacob ST, Crozier I, Fischer WA, 2nd, et al. Ebola virus disease. Nat Rev Dis Primers. 2020;6(1):13. doi:10.1038/s41572-020-0147-3.
  • World Health organization. 10th Ebola outbreak in the Democratic Republic of the Congo declared over; vigilance against flare-ups and support for survivors must continue; 2020. Available from: https://www.who.int/news/item/25-06-2020-10th-ebola-outbreak-in-the-democratic-republic-of-the-congo-declared-over-vigilance-against-flare-upsand-support-for-survivors-must-continue
  • Mukadi-Bamuleka D, Sanogo YO, Bulabula-Penge J, et al. Postmortem surveillance for Ebola virus using OraQuick Ebola rapid diagnostic tests, Eastern Democratic Republic of the Congo, 2019-2020. Emerg Infect Dis. 2022;28(2):420–424. doi:10.3201/eid2802.210981.
  • Mulangu S, Dodd LE, Davey RT, Jr, et al. A randomized, controlled trial of Ebola virus disease therapeutics. N Engl J Med. 2019;381(24):2293–2303. doi:10.1056/NEJMoa1910993.
  • Van Bortel T, Basnayake A, Wurie F, et al. Psychosocial effects of an Ebola outbreak at individual, community and international levels. Bull World Health Organ. 2016;94(3):210–214. Epub 2016 Jan 21. doi:10.2471/BLT.15.158543.
  • Mulenga-Cilundika P, Ekofo J, Kabanga C, et al. Indirect effects of Ebola virus disease epidemics on health systems in the Democratic Republic of the Congo, Guinea, Sierra Leone and Liberia: a scoping review supplemented with expert interviews. Int J Environ Res Public Health. 2022;19(20):13113. doi:10.3390/ijerph192013113.
  • Kasonia K, Tindanbil D, Kitonsa J, et al. The impact of the COVID-19 pandemic on the provision & utilisation of primary health care services in goma, Democratic Republic of the Congo, kambia district, Sierra Leone & Masaka district, Uganda. PLoS One. 2023;18(6):e0286295. doi:10.1371/journal.pone.0286295.
  • Elston JW, Cartwright C, Ndumbi P, et al. The health impact of the 2014-15 Ebola outbreak. Public Health. 2017;143:60–70. doi:10.1016/j.puhe.2016.10.020.
  • Burkle FM. Operationalizing public health skills to resource poor settings: is this the Achilles heel in the Ebola epidemic campaign? Disaster Med Public Health Prep. 2015;9(1):44–46. doi:10.1017/dmp.2014.95.
  • Mukadi-Bamuleka D, Mambu-Mbika F, De Weggheleire A, et al. Efficiency of field laboratories for Ebola virus disease outbreak during chronic insecurity, Eastern Democratic Republic of the Congo, 2018-2020. Emerg Infect Dis. 2023;29(1):1–9. doi:10.3201/2901.221025.
  • Nakiire L, Mwanja H, Pillai SK, et al. Population movement patterns among the Democratic Republic of the Congo, Rwanda, and Uganda during an outbreak of Ebola virus disease: results from community engagement in two districts - Uganda, march 2019. MMWR Morb Mortal Wkly Rep. 2020;69(1):10–13. doi:10.15585/mmwr.mm6901a3.
  • Dramé ML, Ferrinho P, Martins MRO. Impact of the recent Ebola epidemic with pandemic potential on the economies of Guinea, Liberia and Sierra Leone and other West African countries. Pan Afr Med J. 2021;40:228. doi:10.11604/pamj.2021.40.228.28391.
  • Masumbuko-Claude K, Underschultz J, Hawkes MT. Social resistance drives persistent transmission of Ebola virus disease in Eastern Democratic Republic of Congo: a mixed-methods study. PLoS One. 2019;14(9):e0223104. doi:10.1371/journal.pone.0223104.
  • James M, Mansaray A, Thige FO, et al. Continuity and rupture in crisis: from Ebola to COVID-19 in Sierra Leone and the Eastern Democratic Republic of the Congo. Glob Public Health. 2023;18(1):2259959.
  • Elmahdawy M, Elsisi GH, Carapinha J, et al. Ebola virus epidemic in west africa: global health economic challenges, lessons learned, and policy recommendations. Value Health Reg Issues. 2017;13:67–70. doi:10.1016/j.vhri.2017.08.003.
  • Bowles J, Hjort J, Melvin T, et al. Ebola, jobs and economic activity in Liberia. J Epidemiol Community Health. 2016;70(3):271–277. doi:10.1136/jech-2015-205959.
  • Nachega JB, Mbala-Kingebeni P, Otshudiema J, et al. Responding to the challenge of the dual COVID-19 and Ebola epidemics in the Democratic Republic of Congo-priorities for achieving control. Am J Trop Med Hyg. 2020;103(2):597–602. 20) doi:10.4269/ajtmh.20-0642.
  • Mbala-Kingebeni P, Aziza A, Di Paola N, et al. Medical countermeasures during the 2018 Ebola virus disease outbreak in the North kivu and ituri provinces of the Democratic Republic of the Congo: a rapid genomic assessment. Lancet Infect Dis. 2019;19(6):648–657. doi:10.1016/S1473-3099(19)30118-5.
  • Kinganda-Lusamaki E, Black A, Mukadi DB, et al. Integration of genomic sequencing into the response to the Ebola virus outbreak in Nord kivu, Democratic Republic of the Congo. Nat Med. 2021;27(4):710–716. doi:10.1038/s41591-021-01302-z.
  • Mbala-Kingebeni P, Pratt CB, Wiley MR, et al. 2018 Ebola virus disease outbreak in équateur province, Democratic Republic of the Congo: a retrospective genomic characterisation. Lancet Infect Dis. 2019;19(6):641–647. Adoi:10.1016/S1473-3099(19)30124-0.
  • Woolsey C, Geisbert TW. Current state of Ebola virus vaccines: a snapshot. PLoS Pathog. 2021;17(12):e1010078. 24) doi:10.1371/journal.ppat.1010078.
  • Tambo E, Ugwu EC, Ngogang JY. Need of surveillance response systems to combat Ebola outbreaks and other emerging infectious diseases in African countries. Infect Dis Poverty. 2014;3:29. (25) doi:10.1186/2049-9957-3-29.
  • Milligan ID, Gibani MM, Sewell R, et al. Safety and immunogenicity of novel adenovirus type 26- and modified vaccinia Ankara-vectored Ebola vaccines: a randomized clinical trial. JAMA. 2016;315(15):1610–1623. doi:10.1001/jama.2016.4218.
  • Watson-Jones D, Kavunga-Membo H, Grais RF, et al. Protocol for a phase 3 trial to evaluate the effectiveness and safety of a heterologous, two-dose vaccine for Ebola virus disease in the Democratic Republic of the Congo. BMJ Open. 2022;12(3):e055596. doi:10.1136/bmjopen-2021-055596.
  • Mukadi-Bamuleka D, Ahuka-Mundeke S, Ariën KK. Ebola virus: DRC field laboratories’ rapid response. Nature. 2022;604(7905):246. doi:10.1038/d41586-022-01005-6.
  • Mbala-Kingebeni P, Villabona-Arenas CJ, Vidal N, et al. Rapid confirmation of the Zaire Ebola virus in the outbreak of the Equateur province in the Democratic Republic of Congo: implications for public health interventions. Clin Infect Dis. 2019;68(2):330–333. doi:10.1093/cid/ciy527.
  • Mukadi-Bamuleka D. Implementation and evaluation of new tools for Ebola virus disease response during outbreaks in Eastern Democratic Republic of the Congo: Form rapid diagnostic tests to genomic sequencing [PhD thesis]. Antwerp: University of Antwerp; 2023. https://repository.uantwerpen.be/docstore/d:irua:16591.
  • World Health Organization. Dead and injured following attacks on Ebola responders in the Democratic Republic of the Congo. Available from: https://www.who.int/news/item/28-11-2019-dead-and-injured-following-attacks-on-ebola-responders-in-the-democratic-republic-of-the-congo#:∼:text=Two%20attacks%20in%20eastern%20Democratic,response%20coordination%20office%20in%20Mangina.
  • World Health Organization. Remembering Dr Richard Valery Mouzoko Kiboung. Available from: https://www.who.int/news/item/04-05-2019-remembering-dr-richard-valery-mouzoko-kiboung.
  • Seifert SN, Fischer RJ, Kuisma E, et al. Zaire Ebolavirus surveillance near the bikoro region of the Democratic Republic of the Congo during the 2018 outbreak reveals presence of seropositive bats. PLoS Negl Trop Dis. 2022;16(6):e0010504. doi:10.1371/journal.pntd.0010504.
  • Ilunga Kalenga O, Moeti M, Sparrow A, et al. The ongoing Ebola epidemic in the Democratic Republic of Congo, 2018–2019. N Engl J Med. 2019;381(4):373–383. doi:10.1056/NEJMsr1904253.
  • Ebola Outbreak Epidemiology Team. Outbreak of Ebola virus disease in the Democratic Republic of the Congo, April–May, 2018: an epidemiological study. Lancet. 2018;392(10143):213–221. doi:10.1016/S0140-6736(18)31387-4.
  • Rugarabamu S, Mboera L, Rweyemamu M, et al. Forty-two years of responding to Ebola virus outbreaks in Sub-Saharan Africa: a review. BMJ Glob Health. 2020;5(3):e001955. doi:10.1136/bmjgh-2019-001955.
  • Zwick H, Asobee MS, Mitton IK, et al. Burial workers’ perceptions of community resistance and support systems during an Ebola outbreak in the Eastern Democratic Republic of the Congo: a qualitative study. Confl Health. 2023;17(1):25. doi:10.1186/s13031-023-00521-0.
  • Lacroix A, Mbala Kingebeni P, Ndimbo Kumugo SP, et al. Investigating the circulation of Ebola viruses in bats during the Ebola virus disease outbreaks in the Equateur and North kivu provinces of the Democratic Republic of Congo from 2018. Pathogens. 2021;10(5):557. doi:10.3390/pathogens10050557.
  • Gryseels S, Mbala-Kingebeni P, Akonda I, et al. Role of wildlife in emergence of Ebola virus in Kaigbono (Likati), Democratic Republic of the Congo, 2017. Emerg Infect Dis. 2020;26(9):2205–2209. doi:10.3201/eid2609.191552.
  • Nkuba-Ndaye A, Mukadi-Bamuleka D, Bulabula-Penge J, et al. Added value of an anti-Ebola serology for the management of clinically suspected Ebola virus disease patients discharged as negative in an epidemic context. J Infect Dis. 2022;226(2):352–356. doi:10.1093/infdis/jiac057.
  • Henao-Restrepo AM, Camacho A, Longini IM, et al. Efficacy and effectiveness of an rVSV-vectored vaccine in preventing Ebola virus disease: final results from the Guinea ring vaccination, open-label, cluster-randomised trial (Ebola Ça suffit!). Lancet. 2017;389(10068):505–518. doi:10.1016/S0140-6736(16)32621-6.
  • Mukadi-Bamuleka D, Bulabula-Penge J, De Weggheleire A, et al. Field performance of three Ebola rapid diagnostic tests used during the 2018-20 outbreak in the Eastern Democratic Republic of the Congo: a retrospective, multicentre observational study. Lancet Infect Dis. 2022;22(6):891–900. doi:10.1016/S1473-3099(21)00675-7.